KR102551075B1 - Porous fragrance-releasing molding for improving sleep containing natural ingredients - Google Patents

Abstract

The present invention relates to a scent-emitting body for improving sleep containing natural ingredients, and more particularly, to a porous aromatic body containing a composition for improving sleep containing a conifer extract as an active ingredient. The present invention is a fragrance healing product for improving sleep with natural scent conditions, which is provided as a sleep aid for patients with delayed sleep phase syndrome or depression and insomnia to help improve sleep and obtain the effect of forest bathing. A scent diffusing agent product for improvement is provided.

Description

Porous fragrance-releasing molding for improving sleep containing natural ingredients}

The present invention relates to a scent-emitting body for improving sleep containing natural ingredients, and more particularly, to a porous aromatic body containing a composition for improving sleep containing a conifer extract as an active ingredient.

The present invention is a study conducted with the support of Gyeonggi-do Economic Science Promotion Agency (foundation) with financial resources of Gyeonggi-do in 2020 [research project name: 2020 Gyeonggi-do sleep products and service commercialization support project additional implementation plan announcement (R&D field), research project name: Development of a source introduction for sleep-inducing forest healing products from ingredients derived from pine trees in Gapyeong, Gyeonggi-do, Host organization: Microbiome Life Science Co., Ltd., contribution rate: 100/100, research period: 2020.04.01 ~ 2020.11.30].

In general, a person's sleep is a valuable time that occupies one third of 24 hours a day. However, most people know that sleeping time is a time to rest.

However, sleep is not a time to rest, but a time to recharge for the next activity of human beings. It helps the activity of the brain as well as the five sense organs of the human body to promote metabolism, recharge energy, regenerate, strengthen immunity, and relieve the body's fatigue by concentrating. Sleep is the time to detoxify toxins and self-heal from disease.

Therefore, it is not an exaggeration to say that depending on how deep and comfortable a person sleeps, it becomes vitality for human production activities.

It is well known that sleep has a very important effect on health. Sleep is an active state in which important physiological functions are operated by the brain for the brain. In particular, for humans with a developed brain, the quality of sleep has a great influence on the quality of life, so getting a good night's sleep is very important in improving the quality of life.

In the meantime, as it is known that sleep disorders have a very negative effect on health, various types of drugs for the treatment of sleep disorders have been proposed.

As conventional techniques for improving sleep disorders, screen extracts, jade calligraphy extracts, and citrus peel extracts have been developed as compositions for improving or treating sleep disorders. (Korean Patent Registration No. 10-2157248, Korean Patent Publication No. 10- 2019-0106782, Korea Patent Registration No. 10-2139253, etc.)

In addition, a composition for treating sleep disorders using chemical substances (Korean Patent Publication No. 10-2019-0024593) or a composition for treating sleep disorders using poly-gamma-glutamic acid obtained from fermented Bacillus subtilis has also been proposed. ( Korea Patent Registration No. 10-2149404)

However, these existing compositions have a problem in that they are difficult to apply for treatment of sleep disorders due to high manufacturing cost or insignificant effect.

Therefore, in a situation where the population complaining of sleep disorders is increasing day by day as various causes of stress have recently increased, it is urgent to develop products for improving sleep that can be widely used in various classes through practical use as they are easy to supply and have excellent sleep disorder effects. The situation is.

Korean Patent Registration No. 10-2157248 Korean Patent Publication No. 10-2019-0106782 Korean Patent Registration No. 10-2139253 Korean Patent Publication No. 10-2019-0024593 Korean Patent Registration No. 10-2149404

In order to improve the problems of the prior art as described above, in the present invention, the development of a sleep improvement product that is easy to use while having excellent sleep improvement effect with natural ingredients is a challenge.

Accordingly, an object of the present invention is to provide a fragrance healing product containing a composition for improving sleep or sleep disorder containing a conifer extract.

Another object of the present invention is to provide a scent balm for sleep improvement containing natural ingredients in which alpha-pinene-containing conifer extract is contained in a porous molded article.

In order to solve the above problems, the present invention provides a scent balm for improving sleep containing natural ingredients, which contains a composition for preventing and improving sleep disorders or sleep disorder-related diseases or symptoms containing a conifer extract as an active ingredient in a porous molded body. do.

According to a preferred embodiment of the present invention, the porous molded body may be formed of a membrane film, sheet or matrix having small pores with breathable and waterproof properties and selective gas permeability.

According to a preferred embodiment of the present invention, the membrane film, sheet or matrix may be thermally bonded in a cylindrical or tetrahedral shape.

According to a preferred embodiment of the present invention, the porous molded body may be formed in the form of a tablet made by tableting small-pore powder, porous particles, granules, pellets, microspheres, or powder in a state in which pores are maintained.

According to a preferred embodiment of the present invention, the conifer extract may be supported in the pores of the porous molded body so that the active ingredient for improving sleep is diffused in a sustained release form from the conifer extract.

According to a preferred embodiment of the present invention, the porous molded article may be made of any one or more of wood, fiber, or synthetic resin that is harmless to the human body and the environment.

According to a preferred embodiment of the present invention, the porous molded article may further include a support or form a three-dimensional skeletal structure.

According to a preferred embodiment of the present invention, the scent diffuser may contain 0.01 to 80% by weight of coniferous extract.

The scent diffuser of the present invention can be used in various containers while containing a composition for improving sleep, and can be used as a scent diffuser itself, so it can be used as a scent healing product in a convenient way, and various gaseous components such as phytoncide gradually It emits a scent healing effect similar to forest bathing.

In particular, the present invention provides a phytoncide contact effect by using a coniferous extract, which also serves as a forest bathing action to purify the mind and body. By continuously obtaining the phytoncide effect, not only induces an optimal sound sleep environment, but also induces a long sleep to reduce fatigue and stress. It has the effect of solving the problem and giving vitality to life.

1 is a graph showing the superiority of the smoking lag time reduction effect of the pine nut extract of the present invention compared to the control group.
Figure 2 is a graph showing that the sleep efficiency of the pine nut extract of the present invention is superior to that of the control group.
Figure 3 is a graph showing the comparison of the degree of tension during sleep for the pine nut extract of the present invention is superior to the control group.
Figure 4 is a graph showing the degree of tossing during sleep for the pine nut extract of the present invention compared to the control group.
Figure 5 is a graph showing the overall feeling of sleep for the pine nut extract of the present invention compared to the control group.

Hereinafter, the present invention will be described in more detail as one embodiment.

The present invention relates to a product for improving people's sleep, and is intended to manufacture a product for improving sleep to allow people to feel forest bathing through a sleeping product that has a natural smelling condition in order to induce an optimal sleeping environment.

The product of the present invention can reduce sleep induction period and extend sleep time by improving low sleep quality, irregular sleep time, sleep disorders such as insomnia, and sleep discomfort by using the scent diffusing effect, and can see side effects from chemicals or environmental pollution. It relates to an excellent natural scent treatment or scent healing product for improving sleep that can be safely used by the whole family without worrying about it.

In the case of existing products with a high scent smell provided for a purpose similar to the sleep improvement products of the present invention, they have been provided in various forms such as liquid, solid, and gel to emit fragrance.

However, first of all, although the liquid type is easy to manufacture, the container must be safely fixed because the liquid may flow out and contaminate the surroundings during transportation. Unlike the liquid type, the solid type has no fluidity and does not overflow, so it is relatively easy to move and store. However, in the case of a solid type, a problem of powder scattering may occur, and since the content of aromatic substances is low, the fragrance quickly disappears, so the use time is very low, so there is a problem of poor marketability.

The present invention is a solid product manufactured by improving these problems. A molded body is composed of porous particles having a plurality of pores, and a solid fragrance healing product for improving sleep comprising a conifer extract contained in the pores of the porous particles. Provides a scent diffusing body as

According to a preferred embodiment of the present invention, the phytoncide effect can be given by immersing the coniferous extract in the scent diffuser for improving sleep, so that the phytoncide effect can be continuously obtained by combining the action of forest bathing to purify the mind and body. Therefore, it not only induces an optimal sleep environment, but also extends sleep time to relieve fatigue and relieve stress, thereby giving vitality to life.

Regarding the efficacy of phytoncide, it was long ago known that it was effective in the treatment of pulmonary tuberculosis, etc., and it was thought that health could be restored only by resting while breathing good air in the forest where phytoncide comes out. When you take a forest bath, phytoncide, which refers to various antibacterial substances from plants, enters the body and plays a role in eliminating bad pathogens, pests, and fungi. Components of phytoncide include turpentine oil, phenolic compounds, alkaloids, and glycosides.

These phytoncides are aromatic substances with sterilizing and insecticidal power that trees emit to protect themselves from various bacteria and pests. Therefore, it is used as a raw material for air fresheners, cosmetics, and disinfectants. In addition, phytoncide naturally penetrates into the human body and tries to kill germs like antibiotics. However, since it is a natural substance, it has no side effects that cause resistance, unlike artificially made antibiotics. In addition, since it activates each part of the body, it maintains elastic skin, has an anti-aging effect, stabilizes the nerves, and relieves mental fatigue. Among phytoncides, turpentine oil is representative, and turpentine is the scent that can be smelled when rubbing pine or arborvitae leaves.

These phytoncides invigorate blood activity, quickly discharge waste products from the body and supply fresh nutrients, helping all functions to be active. When the blood is purified and each cell is strengthened, the resistance to germs becomes stronger. As a result, physical strength is strengthened and the body's natural healing power is revived. Forest bathing is a natural health method that relieves physical and mental fatigue and stress through volatile fragrances (phytoncide) emitted by trees.

Phytoncide has an excellent effect that can relieve up to 25-60% of stress experienced in urban space.

The present invention is able to provide a new type of scent diffuser that can simply and easily emit components beneficial to the human body, such as phytoncide, and is particularly effective in improving sleep.

According to the present invention, the amount of phytoncide generally emitted is higher in conifers than in broad-leaved trees and in summer than in winter.

According to a preferred embodiment of the present invention, in order to obtain the above excellent functions, the coniferous extract containing a large amount of phytoncide can be used by being supported on a scent diffuser for improving sleep having conditions for natural scent diffusion.

According to a preferred embodiment of the present invention, instead of inserting a liquid or gel-like material into a selective gas permeable membrane film, sheet, or matrix having breathability and waterproofness to form a scent diffuser, through small pores of the membrane It can be configured so that only gas can be transmitted and emitted. Therefore, when the coniferous extract is supported and used in the scent diffuser of the present invention, the indoor air is purified by deodorization, sterilization, and insect repellent of contaminated air, or the effect of preventing or treating diseases to indoor residents with a therapy effect through fragrance Improving indoor air quality can improve quality of life.

In addition, according to a preferred embodiment of the present invention, it is characterized in that the fragrance emitted from the scent diffuser is continuously diffused for a long time and supplied to the room. In addition, it is manufactured as an aromatherapy product for sleep improvement formed after thermally bonding the slopes, but the initial fragrance can be maintained for a long period of time through the application of a porous molded body having controlled slow-release of coniferous extract. And preferably, such a scent diffusing effect may be composed of a solid scent diffuser to improve the persistence of a scent with a certain intensity.

According to a preferred embodiment of the present invention, it is preferable to use a material that is harmless to the human body and the environment as the porous particles constituting the smell diffuser, which may be made of a porous molded body, and may further include an additional carrier.

According to a preferred embodiment of the present invention, since the porous particles have a porous structure in which pores are formed, the surface area is very large, a three-dimensional skeletal structure is formed, and the coniferous extract, which is helpful in improving sleep, is stably maintained without denaturation of the unique fragrance. can be supported.

In addition, the porous particle of the present invention is a main component containing the coniferous extract helpful for improving sleep, and can play a role in preventing deterioration of the inherent fragrance of the coniferous extract by slowly releasing the supported coniferous extract.

According to a preferred embodiment of the present invention, the average pore diameter of the porous particles for effective support, release, and odor deterioration prevention may be 1 to 100 nm, for example, 10 to 100 nm, for example, 20 to 50 nm. And, the average particle diameter (diameter) may be 1 to 100 nm, for example, 10 to 100 nm.

In addition, according to a preferred embodiment of the present invention, the porosity of the porous particles may be, for example, 70% or more, for example, 80% or more, for example, 90%, in order to improve the carrying rate.

According to a preferred embodiment of the present invention, when the porous particles are used in the form of fine powder, when the coniferous extract helpful for improving sleep is supported, disadvantages such as harmfulness to the human body may occur due to powder scattering after the fragrance is completely emitted. can

Therefore, according to a preferred embodiment of the present invention, in order to improve high-temperature stability and freely process the shape, it is good to use a molded body formed by molding porous particles into a form of microspheres, granules, pellets, tablets, etc. by using a tableting method. The scent-diffusing body of the present invention may include such a molded body.

In addition, it can be used by filling a container such as a membrane with liquid, solid, gel, etc.

According to a preferred embodiment of the present invention, a scent diffuser can be manufactured by supporting a natural material for sleep improvement containing alpha-pinene-containing conifer extract as an active ingredient on the molded article of the present invention.

According to a preferred embodiment of the present invention, conifers used in the conifer extract may be a by-product of conifers.

According to a preferred embodiment of the present invention, the conifers for obtaining the coniferous extract include, for example, pine, metasequoia, blue globose, fir, pine, pine tree, larch tree, Japanese larch tree, birch tree, black birch tree, snow cypress. , one or more of cypress trees may be used. More preferably, a more excellent effect can be obtained when using a pine tree as a coniferous tree.

Therefore, according to a preferred embodiment of the present invention, conifer extract is particularly excellent as a component for improving sleep, and more preferably, pine nut extract can exhibit a more excellent effect. In particular, according to the present invention, it was confirmed that the conifer extract exhibits very excellent effects on lifespan improvement effect, sleep disorder improvement effect, diseases caused therefrom, and diseases caused by improvement of concentration or decrease in concentration.

According to a preferred embodiment of the present invention, as a by-product of conifers used in the conifer extract, at least one of stems, leaves, roots, immature conifers, and mature conifers can be used as an extract. More preferably, extracts of by-products of pine nuts may be used, and preferably, immature conifers, mature conifers extracts, or conifers remaining after removal of pine nuts from pine nuts may be used.

According to one embodiment of the present invention, it was found that pine nuts produced less phytoncide than general conifers, but had no toxicity to the human body. In particular, the phytoncide of pine trees has the highest content of alpha-pinene, which stimulates the cerebral cortex to increase concentration and exercise, and also contains 3-carene and bornyl-acetate, which are known to give unique effects of forest fragrance.

In particular, according to a preferred embodiment of the present invention, among coniferous extracts, pine nut extract has a soothing effect on the central nervous system to give a pleasant feeling, extends sleep time, and helps to have a comfortable sleep. In addition, pine nut extract has a strong antibacterial action that does not cause resistance in the human body, and pine nut extract, a natural substance, has up to 90% of house dust mite repelling effect, so there are no side effects and it is also very effective in preventing allergies.

In the present invention, while conducting continuous research to verify whether various substances have a sound sleep effect, it was found that alpha-pinene contained in pine nut extract had a sedative effect when administered to mice. However, it is surprising that alpha-pinene exhibits a sedative effect at a low concentration, for example, at a concentration of about 25-80 mg/kg, but has a superior effect on improving sleep at a high concentration of about 100 mg/kg or more. confirmed

As described above, according to a preferred embodiment of the present invention, it was confirmed that the sleep improvement effect was very excellent in the coniferous extract containing alpha-pinene, and more preferably, the excellent effect in the pine nut extract.

According to a preferred embodiment of the present invention, the conifer extract of the present invention can be used as a component obtained by extracting using any one of immature conifers and mature conifers, leaves, branches, roots, bark, and the like. More specifically, it is a component obtained using conifers, which contains various physiologically active substances such as alpha-pinene, beta-pinene, di-limonene, and 3-carene, and reduces stress from active oxygen, eliminates insomnia, or improves sleep quality. There is a function.

According to a preferred embodiment of the present invention, the sleep-improving effect of the coniferous extract has an effect of increasing the amount of sleep without impairing the intensity of sleep by, for example, extending the duration of sleep, improving the quality of sleep, Sleep disorders can be prevented or treated.

The coniferous extract of the present invention has been confirmed to be superior to zolpidem, which is widely known for sleep improvement or sleep disorder treatment, and unlike existing drugs, it is a natural material, so it is related to sleep improvement, sleep disorder or unstable life, poor concentration, etc. without side effects. It is confirmed that it can be applied very preferably to the prevention and treatment of diseases.

According to a preferred embodiment of the present invention, as a composition capable of inducing quality sleep and improving sleep disorder or anxiety, a natural material for improving sleep containing an alpha-pinene-containing conifer extract is supported on a porous molded body to release the sustained release. It is possible to provide a scent diffuser that induces scent diffusion.

According to a preferred embodiment of the present invention, the content ratio of the porous molded article and the coniferous extract helpful for improving sleep can affect the supporting ratio and molding stability. Specifically, if the weight ratio of the coniferous extract that helps improve sleep is excessively increased, the concentration of the porous molded body, which is the main material to be supported, exceeds the concentration, so the loading rate may decrease. If the content ratio of the extract is too small, the scent diffusing effect is also insignificant, but the bonding force with the microparticles or microparticles constituting the porous molded body is weakened, and the fragrance may be consumed quickly.

Therefore, according to a preferred embodiment of the present invention, the weight ratio of the coniferous extract helpful for improving sleep and the porous molded article may be preferably 2:8 to 4:6.

According to a preferred embodiment of the present invention, the porous particles constituting the porous molded article may include at least one selected from the group consisting of silica, zeolite, activated carbon and acrylic resin particles, starch, tapioca starch, dextrin, and modified dextrin. there is. For example, beta-cyclodextrin.

According to a preferred embodiment of the present invention, the porous molded article preferably uses a material harmless to the human body and the environment, and may further include an additional carrier.

According to a preferred embodiment of the present invention, the coniferous extract helpful for improving sleep can be stably supported without deterioration of the inherent fragrance due to the configuration of the porous molded body. In addition, the porous molded article can play a role of preventing deterioration of the inherent fragrance of the conifer extract by gradually releasing the supported conifer extract to help improve sleep.

In addition, according to a preferred embodiment of the present invention, the porosity of the porous molded body is, for example, 70% or more, for example, 80% or more, for example, 90%, in order to improve the carrying rate of the coniferous extract supported on the porous molded body. can

According to a preferred embodiment of the present invention, the present invention is a scent treatment product for improving sleep with a natural scent diffusing condition, which is composed of a fragrance healing method for patients with delayed sleep phase syndrome or depression and insomnia, and is a sleep aid product can be provided with

According to a preferred embodiment of the present invention, the scent diffuser may include 0.01 to 80% by weight of the conifer extract.

According to a preferred embodiment of the present invention, the coniferous tree extract may additionally contain aromatic essential oil or essential oil, for example, an extract by a water-soluble solvent.

According to a preferred embodiment of the present invention, specific examples of essential oils include lavender, grapefruit, geranium, cinnamon leaf, tea tree, cedarwood, orange, eucalyptus, and bergamot. , lemon, lime, mandarin, myrrh, neroli, niaouli, peppermint, pine, rosemary, chamomile, ylang ylang, neem, frankincence, benzo Contains an oil obtained from at least one selected from the group consisting of benzoin, helichrysum, phytoncide, conifer extract, cypress extract, pine conifer oil, rosewood, sandalwood, etc. can do.

In addition, according to a preferred embodiment of the present invention, the conifer extract may further include a solvent and an additive, and the solvent may include ethanol, water, glycerin, silicone oil, and the like, and may further include an additive such as color can do.

The coniferous extract used in the present invention is not limited to the main flavoring substances described above, and may include any general vegetable oil without limitation, and may include solvents and additives commonly used for other fragrances without particular limitation. there is.

According to a preferred embodiment of the present invention, the manufacturing method of the solid-type aromatherapy product for improving sleep according to the present invention is described as an example,

1) mixing porous particles with a coniferous extract that helps improve sleep;

2) Injecting the mixture of 1) into a casting, cooling, and applying high pressure to form a porous molded body in which the conifer extract is supported.

According to a preferred embodiment of the present invention, in the manufacturing method of the solid fragrance treatment product for improving sleep according to the above method, the conifer extract helpful for improving sleep is uniformly distributed in the porous particles composed of the porous molded body. It can have a structure in the form of

In addition, the present invention can provide a solid fragrance treatment product for improving sleep having a sustained release type by supporting the coniferous extract helpful for improving sleep in the pores of porous particles, improving the durability of the fragrance, and deteriorating early odor. can prevent

According to the present invention, a liquid or gel material is inserted into a selective gas permeable membrane film, sheet, or matrix having breathability and waterproof properties, so that only gas is permeated through small pores of the membrane and released.

According to a preferred embodiment of the present invention, conventionally developed products such as the selective gas permeable membrane film, sheet, and matrix having breathability and waterproofness may be used.

According to a preferred embodiment of the present invention, for example, 60 to 80% by weight of gel, 0.01 to 20% by weight of coniferous extract, and 5 to 20% by weight of purified water are included, and 60 days or more in the case of a jelly or gel at room temperature of 20 to 25 ° C. It can be sustainable, so it can be made into a scent diffuser for improving sleep that can maintain optimal sleep.

According to another aspect of the present invention a) mixing the gel phase and purified water; b) mixing the coniferous extract with the mixture of step a); c) it can be prepared as an aromatherapy product for improving sleep, which includes the step of putting the mixture prepared through steps a)-b) in a hermetically sealed container to form a gel or jelly.

If the gel phase is less than 30% by weight, it may be difficult to form a gel phase or jelly phase in a semi-liquid state, and if it exceeds 80% by weight, it is not flowable like a solid and cannot be moved to a container for making a gel phase or jelly phase.

According to a preferred embodiment of the present invention, the gel or jelly phase may be one or more selected from the group of starch, tapioca, mung bean, potato, sweet potato, corn, cellulose, CMC, carbomer, carrageenan, KEPCO, gelatin, and gellan gum. More specifically, carbomers are preferred.

According to the present invention, the carbomer can be used as a gelling agent. A gelling agent generally refers to a substance or composition that changes a liquid into a semi-solid gel when mixed with a liquid. Conventional gel-like products mostly use gelatin or gellan gum as a gelling agent. However, in the case of a product made of gelatin or gellan gum, when a certain period of time elapses at room temperature, the gel evaporates and contracts, and the shape is distorted or the initial shape is not maintained. In addition, the product gelled with gelatin or gellan gum has a disadvantage in that the volatilization of the gel proceeds rapidly at a high temperature of 40 ° C. or more, and thus the stability regarding durability is poor.

On the other hand, the gelatin has a disadvantage in that manufacturing cost increases due to the addition of a process of alkali or acid treatment of cow or pork skins.

The purified water is used as a solvent and is used for uniform mixing and gelation of each of the above-described compositions.

According to a preferred embodiment of the present invention, if the conifer extract is less than 0.01% by weight, fragrance treatment is impossible because it does not have a fragrance, and if it exceeds 20% by weight, it cannot be mixed with the gel compositions and oil is separated.

Hereinafter, a scent therapy product for improving sleep that can maintain optimal sleep by replacing the gel or jelly after a cycle of 60 days according to one embodiment of the present invention will be described in detail.

However, the present invention may be embodied in many different forms and is not limited to the embodiments described herein.

(1) First mixing step

First, a first mixture is prepared by mixing a gel or jelly phase and purified water. In one embodiment, the first mixture may include 30 to 80% by weight of gel or jelly, and 5 to 20% by weight of purified water. The gel phase may be at least one selected from the group of starch, tapioca, mung bean, potato, sweet potato, corn, cellulose, CMC, carbomer, carrageenan, KEPCO, gelatin, and gellan gum. More specifically, carbomers are preferred.

In another embodiment, the carbomer may be evenly dispersed in purified water in powder form. Injecting the carbomer at the beginning of the manufacturing step of the gel-like or jelly-like fragrance treatment product for improving sleep is to uniformly disperse the carbomer in the gel-like or jelly-like composition.

In this step, the first mixture is prepared by mixing for 30 minutes or more and 60 minutes or less at a speed of 20 rpm or more and 60 rpm or less using a known stirrer. If the speed of the agitator is less than 20 rpm, the first mixture may not be uniformly mixed, and agglomeration may occur in which some powders form lumps. On the other hand, if the speed of the stirrer exceeds 60 rpm, a phenomenon in which the gel phase or jelly phase becomes hard may occur.

In addition, if it is less than 30 minutes, a phenomenon of separation occurs after a long time in a mixed state, and if it exceeds 60 minutes, a phenomenon in which the coniferous extract is lost due to frictional heat during stirring may occur.

(2) Second mixing step

It is prepared by adding coniferous extract to the first mixture. Coniferous extract contains 0.01-20% by weight. The conifer extract uses an extract extracted using by-products such as immature and mature conifers, branches, and leaves. More specifically, mature conifers are preferred.

(3) Gelation step

Next, a step of terminating the mixing process of the second mixture and making it into a gel or jelly state. In one embodiment, after the second mixture is placed in a container through the above-described steps, the selective gas permeable membrane is hot-pressed, and then the silver foil wrapper is thermally bonded to the four sides to form a gel or jelly-like fragrance treatment product for improving sleep. Sealing the container is to prevent the coniferous extract from flying away while the second mixture is in a gel or jelly state.

Example 1

It relates to a fragrance treatment product for improving sleep in a gel or jelly form containing carbomer.

First, a first mixture was prepared by mixing carbomer and purified water. In one embodiment, 80% by weight of the carbomer was used, and 19% by weight of purified water was used.

Next, the coniferous extract was added to the first mixture and mixed for 30 minutes at 60 rpm using an agitator to prepare a second mixture. In one embodiment, 1% by weight of coniferous extract was used.

The second mixture is put in an airtight container and stored at room temperature for one day to finally complete a gel or jelly scent treatment product for sleep improvement containing carbomer.

Example 2

In order to manufacture a fragrance treatment product for sleep improvement with conditions of natural direction in the solid phase containing conifer extract that is helpful for sleep improvement, first, porous particles, beta-cyclodextrin, and conifer extract are mixed at a ratio of 2:8, and then sieved. After making it homogeneous using a tablet was prepared using a tablet press.

Test Example: Measurement of Sleep Effect of Pine Extract Sleep Improvement Composition Material

In order to objectively evaluate the sound sleep effect of the pine nut extract (conifer extract from which pine nuts have been removed) sleep improvement composition according to the present invention, using the pine nut extract sleep improvement composition material prepared in Table 1, brainwaves and safety during sleep , electrocardiogram was measured to conduct polysomnography and subjective evaluation of sleep. The specific method is as follows.

1. Subject

The subjects of the survey were 200 women in their 10s to 40s who were healthy, not currently taking drugs, and who were not drunk.

Subjects were asked to refrain from excessive exercise or excessive drinking on the day before the experiment, and on the day of the experiment, they were asked to refrain from smoking, drinks, drugs, and chewing gum that could affect the central nervous system and olfactory sense. As an experiment targeting adult women, it was reported that there was a correlation between the change in the sense of fragrance according to the woman's sexual cycle, and the menstrual cycle and mood of the woman, so it was conducted considering the menstrual cycle of the research subject.

2. Experimental samples

For the experimental sample, as a comparative example, a non-scented condition and a pine nut extract sleep improvement composition material were used. Incense was constantly presented to the sleep laboratory, and polysomnography was performed by measuring brain waves (EEG), safety level (EOG), and electrocardiogram (ECG) while sleeping.

3. Experiment site

The experiment was conducted in a sleep laboratory (4.8 m x 3 m x 2.4 m) built by the Institute of Standards and Science, and a soundproofing device was installed inside to exclude the influence of the external environment during the experiment. The sleeping laboratory was maintained at constant temperature and humidity, and the temperature was 24 ℃ and the humidity was 40%.

4. Measurement method

Physiological signals during sleep were measured by electroencephalogram (EEG), safety level (EOG), and electrocardiogram (ECG) using a polysomnography device. The subjective evaluation of sleep was written after the experiment about the sleep felt by the subjects.

5. Experimental sequence

Polysomnography was performed three times under the conditions of the control example and the example.

In order to exclude the effect on sleep, samples were randomly conducted for each subject, and before conducting this experiment, they were asked to sleep in the sleep laboratory once or twice to adapt to the sleep laboratory. The sleeping time was to be taken for 2 hours during the week, and each subject was allowed to sleep at the same time. In addition, subjective evaluation of sleep was collected through a questionnaire after sleep.

6. Analysis method

While the subjects were sleeping, physiological signals were measured using a polysomnography device, and sleep stages were analyzed using the measured signals. The international standard method of Rechtschaffen and Kales (1968) was used to determine the sleep stage.

Using the divided sleep stages, sleep latency and sleep efficiency were compared. In addition, after performing sleep under given conditions, subjective feelings were collected through questionnaires and statistical analysis was performed using t-test using SPSS program.

7. Experimental results

go. sleep latency

condition control group 1 control group 2 control group 3 Experiment group 1 experimental group 2 Experiment group 3 Average value of elevation delay time (minutes) 35.12 34.89 35.77 29.21 29.45 29.33

As can be seen in Table 1 and FIG. 1, the average of the elevation delay time was shorter in the experimental group containing the pine nut extract than in the control group without the pine extract, which means that the experimental group containing the pine nut extract fell to the surface in a short time. means lifting

me. sleep efficiency

Sleep efficiency is the ratio of the total sleep time to the time in bed, and the ratio of the time spent sleeping during the experiment period was compared.

The results of the sleep efficiency are shown in Table 2 and FIG. 2 below.

condition control group 1 control group 2 control group 3 Experiment group 1 experimental group 2 Experiment group 3 Sleep efficiency (%) 55.40 56.22 55.20 63.70 63.0 63.2

As can be seen in Table 2 and FIG. 2, when looking at the average of sleep efficiency, the experimental group containing the pine nut extract had higher sleep efficiency than the control group, which was longer than the experimental group containing the pine nut extract without fragrance. means to fall asleep while

all. subjective evaluation

① Tension level

Table 3 and FIG. 3 below are charts showing the degree of tension during sleep compared to normal sleep.

condition control group 1 control group 2 control group 3 Experiment group 1 experimental group 2 Experiment group 3 Tension level compared to usual (points) 0.92 0.65 0.52 1.12 1.04 1.17

As can be seen in Table 3 and FIG. 3, the average sleep efficiency was higher in the experimental group containing the pine nut extract sleep improvement composition material than in the control group, which indicates that the experimental example containing the pine nut extract sleep improvement composition material has a fragrance This means that you sleep for a longer period of time than when you are not.

② Degree of toss and turn

Table 4 and FIG. 4 below are charts showing the degree of tossing during sleep compared to usual.

condition control group 1 control group 2 control group 3 Experiment group 1 experimental group 2 Experiment group 3 Degree of tossing and turning compared to usual (points) -0.14 -0.20 -0.18 0.85 0.88 0.84

As can be seen in Table 4 and FIG. 4, the control group responded that they tossed more than usual, and the experimental group responded that they tossed less than usual.

③ Overall sleep level

Table 5 and FIG. 5 below are charts showing the overall feeling of sleep compared to usual.

condition control group 1 control group 2 control group 3 Experiment group 1 experimental group 2 Experiment group 3 Overall sleep satisfaction (points) 0.32 0.52 0.48 0.96 0.94 0.97

As can be seen in Table 5 and FIG. 5, in the control condition, a similar level of sleep was obtained compared to usual, but in the experimental group condition, the answer was that he had a good sleep as usual. Sleep satisfaction was found to be very good.

Claims (8)

A composition for improving sleep or preventing and improving sleep disorder-related diseases or symptoms containing a conifer extract as an active ingredient is contained in a porous molded body made of a membrane film, sheet or matrix having small pores having selective gas permeability and breathability and waterproofness. In the porous molded body, a gel phase containing carbomer is inserted,
The porous molded body is made of a cylindrical or tetrahedral shape thermally bonded; The average pore diameter of the porous molded body is 50 to 100 nm; The alpha-pinene concentration of the coniferous extract is 30 mg/kg or more; The weight ratio of the conifer extract and the porous molded article is 2:8 to 4:6; containing beta-cyclodextrin in the porous molded body; The porous molded article is immersed in the gel phase 60-80% by weight, coniferous extract 0.01-20% by weight and purified water 5-20% by weight, so that the coniferous extract is porous so that the active ingredient for improving sleep from the coniferous extract is released in a sustained release form. A scent diffuser for improving sleep containing natural ingredients, characterized in that supported in the pores of the molded body.
delete delete delete delete The scent diffuser for improving sleep containing natural ingredients according to claim 1, wherein the porous molded body is made of at least one of wood, fiber, and synthetic resin that is harmless to the human body and the environment. The smell diffuser for improving sleep containing natural ingredients according to claim 1, wherein the porous molded body further includes a carrier or has a three-dimensional skeletal structure. delete

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