KR20220071434A - Porous fragrance-releasing molding for improving sleep containing natural ingredients - Google Patents

Abstract

The present invention relates to a sleep improving fragrance-releasing member containing natural ingredients and, more specifically, relates to a porous aromatic member including a sleep improving composition containing a Pinophyta extract as an active ingredient. In addition, provided are a sleep aid for patients with delayed sleep phase syndrome, depression and insomnia as a fragrance healing product for improving sleep with natural fragrance-releasing conditions, and a sleep improving fragrance-releasing member product which helps improve sleep quality and obtains a forest bathing effect.

Description

Fragrance for improving sleep containing natural ingredients {Porous fragrance-releasing molding for improving sleep containing natural ingredients}

The present invention relates to a sleep-improving fragrance containing natural ingredients, and more particularly, to a porous fragrance containing a sleep-improving composition containing a conifer extract as an active ingredient.

The present invention is a research carried out with the support of Gyeonggi Provincial Economic Science Promotion Agency with the resources of Gyeonggi Province in 2020 [Research project name: Announcement of additional implementation plan for the 2020 Gyeonggi Province sleep products and services commercialization support project (R&D field), research project name: Development of a source introduction for sleep-inducing forest healing products from ingredients derived from pine trees in Gapyeong, Gyeonggi-do.

In general, human sleep is a precious time, accounting for one-third of the 24 hours a day. However, most people think of sleeping time as rest time.

However, sleep is not a time to rest, but a time to recharge for the next activity of humans. Sleep is the time to detoxify toxins and self-heal from disease.

Therefore, it is not an exaggeration to say that depending on how deep and comfortable you get a good night's sleep, it becomes vital to human productive activities.

It is well known that sleep has a very important effect on health. Sleep is an active state in which important physiological functions are operated by the brain for the brain. It is an adaptive behavior maintained as a high level of physiological function rather than a simple downtime, and is a biological defense technology. In particular, for humans with a developed cerebrum, the quality of sleep has a large influence on the quality of life, so getting a good night's sleep is very important for improving the quality of life.

As it is known that sleep disorders have a very negative effect on health, various types of drugs for the treatment of sleep disorders have been proposed.

As a conventional technique for improving sleep disorders, folding screen extract, octopus calligraphy extract, citrus peel extract, etc. have been developed as compositions for improving or treating sleep disorders. (Korean Patent Registration No. 10-2157248, Korean Patent Publication No. 10- See 2019-0106782, Korean Patent Registration No. 10-2139253, etc.)

In addition, a composition for treating sleep disorder using a chemical (Korean Patent Publication No. 10-2019-0024593) or a composition for treating sleep disorder using polygamma glutamic acid obtained from a fermented product of Bacillus subtilis has also been proposed. ( Korean Patent Registration No. 10-2149404)

However, these existing compositions have a problem in that they are difficult to apply for the treatment of sleep disorders because the manufacturing cost is high or the effect is insignificant.

Therefore, in a situation in which the number of people complaining of sleep disorders is increasing day by day due to the increasing number of causes of various stresses, it is urgent to develop a sleep improvement product that can be widely used in various classes through practical use due to the easy supply of raw materials and excellent sleep disorder effect. the current situation.

Korean Patent Registration No. 10-2157248 Korean Patent Publication No. 10-2019-0106782 Korean Patent Registration No. 10-2139253 Korean Patent Publication No. 10-2019-0024593 Korean Patent Registration No. 10-2149404

In order to improve the problems of the prior art as described above, in the present invention, it is a problem to develop a product for improving sleep that is convenient to use while having excellent sleep improvement effect with natural ingredients.

Accordingly, it is an object of the present invention to provide a fragrance healing product containing a composition for improving sleep or sleep disorders containing a conifer extract.

Another object of the present invention is to provide a sleep-improving fragrance containing natural ingredients in which an alpha-pinene-containing conifer extract is contained in a porous molded article.

In order to solve the above problems, the present invention provides a sleep-improving fragrance containing a natural ingredient comprising a composition for improving sleep or preventing and improving sleep disorder-related diseases or symptoms containing a conifer extract as an active ingredient in a porous molded article do.

According to a preferred embodiment of the present invention, the porous molded article may be formed of a membrane film, sheet or matrix having small pores having air permeability and selective gas permeability having breathability and water resistance.

According to a preferred embodiment of the present invention, the membrane film, sheet or matrix may be formed in a cylindrical or tetrahedral heat-bonded form.

According to a preferred embodiment of the present invention, the porous molded body may be in the form of a tablet made by tableting a powder having small pores, porous particles, granules, pellets, microspheres, or powder with the pores maintained.

According to a preferred embodiment of the present invention, the coniferous extract may be supported in the pores of the porous molded body so that the active ingredient for improving sleep is released from the coniferous extract in a sustained-release manner.

According to a preferred embodiment of the present invention, the porous molded body may be made of any one or more of wood, fiber, and synthetic resin harmless to the human body and the environment.

According to a preferred embodiment of the present invention, the porous molded body may further include a support or form a three-dimensional skeletal structure.

According to a preferred embodiment of the present invention, the fragrance may contain 0.01 to 80% by weight of the conifer extract.

The fragrance of the present invention can be used in various containers with the composition for improving sleep, and can be used as a fragrance itself, so it can be used as a fragrance healing product in a convenient way, and various gaseous components such as phytoncide are gradually released. It is emitted, and a scent healing effect similar to forest bathing can be obtained.

In particular, the present invention provides a phytoncide contact effect by using a coniferous extract, which serves as a forest bath to purify mind and body and continuously obtains a phytoncide effect, thereby inducing an optimal sleep environment as well as taking a long deep sleep to reduce fatigue and stress It has the effect of releasing energy and giving vitality to life.

1 is a graph showing the superiority of the effect of reducing smoking delay time for an extract of pine needles of the present invention compared to that of a control group.
Figure 2 is a graph showing that the sleep efficiency of the pine pine extract of the present invention is superior to that of the control group by comparison.
3 is a graph showing the superiority of the sleep tension for the pine pine extract of the present invention compared to the control group.
4 is a graph showing that the degree of toss and downs during sleep for the Pine pine extract of the present invention is superior to that of the control group.
5 is a graph showing that the overall feeling of sleep for the pine nut extract of the present invention is superior to that of the control group.

Hereinafter, the present invention will be described in more detail as one embodiment as follows.

The present invention relates to a product for improving human sleep, and to manufacture a product for improving sleep so that one can feel forest bathing through a sleeping product having a natural scented condition in order to induce an optimal sleep environment.

The product of the present invention can reduce sleep induction period and extend sleep time by improving low sleep quality, irregular sleep time, sleep disorders such as insomnia and sleep discomfort by using the fragrance effect, and side effects from chemicals or environmental pollution It relates to an excellent natural fragrance treatment or fragrance treatment product for improving sleep that can be safely used by the whole family without worrying about it.

The present invention has been provided in various forms, such as liquid, solid, gel, and the like, in order to emit a fragrance in the case of a product having a high fragrance in the past, which is provided for a similar purpose to the product for improving sleep.

However, first, the liquid type is easy to manufacture, but the container must be securely fixed because the liquid may flow out during transportation and contaminate the surroundings. Unlike the liquid type, the solid type has no fluidity and does not overflow, so it is relatively easy to move and store. However, in the case of the solid type, there may be a problem of flying powder, and since the content of the aromatic substance is low and the fragrance is quickly dissipated, the use time is very short, and there is a problem that the commercial property is deteriorated.

The present invention is a solid product manufactured by improving these problems, comprising a molded body made of porous particles having a plurality of pores, and comprising a conifer extract contained in the pores of the porous particles. It provides a scent diffusing body as

According to a preferred embodiment of the present invention, a phytoncide effect can be given by immersing a conifer extract in a sleep-improving fragrance, so that the phytoncide effect can be continuously obtained while also serving as a forest bath to purify the mind and body. Therefore, it not only induces an optimal sleep environment, but also relieves fatigue by extending sleep time, relieves stress, and gives vitality to life.

As for the efficacy of phytoncide, it has long been known to be effective in the treatment of pulmonary tuberculosis, and it was thought that health could be restored only by recuperating while breathing in the good air in the forest where phytoncide came out. When you take a forest bath, phytoncides, which are various antibacterial substances from plants, enter your body and play a role in getting rid of bad pathogens, pests, and fungi. The constituent substances of phytoncide are phenolic compounds including turpentine, alkaloids, glycosides, and the like.

These phytoncides are aromatic substances with bactericidal and insecticidal power that trees emit to protect themselves from various bacteria and pests. Therefore, it is used as a raw material for air fresheners, cosmetics, and disinfectants. Also, phytoncides naturally penetrate the human body and try to kill bacteria like antibiotics. However, as it is a natural substance, it is characterized by no side effects that cause resistance, unlike artificially made antibiotics. In addition, it activates each part of the body, so it maintains elastic skin, has an anti-aging effect, stabilizes nerves, and relieves mental fatigue. Among the phytoncides, turpentine oil is representative, and turpentine is the scent that can be smelled when rubbing the leaves of pine or arborvitae.

These phytoncides help the blood to be active, wastes from the body are quickly discharged, and fresh nutrients are supplied, so all functions are active. When the blood is purified and each cell becomes strong, the resistance to germs becomes stronger. Therefore, the physical strength is strengthened and the body's natural healing power is revived. Forest bathing is a natural health method that relieves mental and physical fatigue and stress through volatile aromatic substances (phytoncide) emitted by trees.

Phytoncide has an excellent effect of relieving 25 to 60% of the stress received in an urban space.

The present invention can provide a new type of scent emitting body that is effective in improving sleep while being able to easily and easily radiate components beneficial to the human body, such as phytoncide.

According to the present invention, generally, the amount of phytoncide emitted by conifers is larger than that of broad-leaved trees, and is larger in summer than in winter.

According to a preferred embodiment of the present invention, in order to obtain the excellent functions as described above, a conifer extract containing a large amount of phytoncide can be used by supporting it in a scenting body for improving sleep having a condition of natural scenting.

According to a preferred embodiment of the present invention, a liquid or gel-like material is inserted into a selective gas permeable membrane film, sheet, or matrix having breathability and waterproofness to constitute the perfume, instead of coming out through the small pores of the membrane. It can be configured so that only gas can permeate and diverge. Therefore, when the coniferous extract of the present invention is supported and used, the indoor air is purified by deodorizing, sterilizing, and insect repellent of polluted air, or the effect of preventing or treating diseases for indoor residents through the therapeutic effect through incense and It can improve the quality of life by improving indoor air quality.

In addition, according to a preferred embodiment of the present invention, it is characterized in that the scent emitted from the scent diffusing body is configured to be continuously scented for a long time to be supplied to the room. In addition, it is manufactured as a sleep improvement fragrance treatment article formed after thermal bonding of the slopes, but the initial fragrance can be maintained for a long period of time through application of a porous molded article with controlled sustained release of the conifer extract. And preferably, such a scent diffusing effect may be made of a solid scent diffusing body so as to improve the scent persistence of a certain strength.

According to a preferred embodiment of the present invention, it is preferable to use a material harmless to the human body and the environment as the porous particles constituting the scent diffusing body that can be made of the porous molded body, and may further include an additional carrier.

According to a preferred embodiment of the present invention, since the porous particles have a porous structure in which pores are formed, they have a very large surface area, form a three-dimensional skeletal structure, and are stable without denaturing the unique odor of the conifer extract which helps to improve sleep. can be supported.

In addition, the porous particle of the present invention is a main component for supporting the coniferous extract that helps to improve sleep, and by slowly releasing the supported coniferous extract, it can serve to prevent denaturation of the unique smell of the coniferous extract.

According to a preferred embodiment of the present invention, the average pore diameter of the porous particles for effective loading, release, and prevention of odor change as described above may be 1 to 100 nm, for example 10 to 100 nm, for example 20 to 50 nm. and the average particle diameter (diameter) may be 1 to 100 nm, for example, 10 to 100 nm.

Further, according to a preferred embodiment of the present invention, the porosity of the porous particles may be, for example, 70% or more, for example, 80% or more, for example, 90% in order to improve the loading ratio.

According to a preferred embodiment of the present invention, when the porous particles are used in the form of fine powder, when the conifer extract, which helps to improve sleep, is supported, the fragrance is completely emitted and then there are disadvantages such as harm to the human body due to the powder flying, etc. can

Therefore, according to a preferred embodiment of the present invention, in order to improve high temperature stability and freely process the shape, it is preferable to use a molded article formed in the form of microspheres, granules, pellets, tablets, etc. by using a tableting method of porous particles. The scent emitting body of the present invention may include such a molded body.

In addition, it can be used by filling liquid, solid, gel, etc. in containers such as membranes.

According to a preferred embodiment of the present invention, a scent emitting body can be manufactured by supporting a natural material for improving sleep containing a conifer extract containing alpha pinene as an active ingredient in the molded body of the present invention.

According to a preferred embodiment of the present invention, the conifers used in the extract of conifers may be byproducts of conifers.

According to a preferred embodiment of the present invention, as the conifers for obtaining the conifer extract, for example, pine, metasequoia, blue globular, fir, pine, cypress, Japanese cedar, birch, birch, and arborvitae. , at least one of cypress trees may be used. More preferably, when a cypress tree is used as a conifer, a more excellent effect can be obtained.

Therefore, according to a preferred embodiment of the present invention, as a component for improving sleep, the conifer extract is particularly excellent, and more preferably, the pine pine extract can exhibit a more excellent effect. In particular, according to the present invention, it was confirmed that the conifer extract exhibits very excellent effects on life improvement effect, sleep disorder improvement effect, diseases resulting from them, and diseases caused by improvement of concentration or decreased concentration.

According to a preferred embodiment of the present invention, as a by-product of conifers used in the coniferous extract, one or more of stems, leaves, roots, immature conifers and mature conifers may be used as an extract. More preferably, an extract of a by-product of pine nuts may be used, and preferably, an immature conifer, an extract of a mature conifer, or a conifer remaining after removing the pine nuts from a pine tree may be used.

According to one embodiment of the present invention, it has been found that cypress has no toxicity to the human body, but produces less phytoncide than general conifers. In particular, the phytoncide of Pine pine has the highest content of alpha-pinene, which stimulates the cerebral cortex to increase concentration and exercise, and also contains 3-carene, bonyl-acetate, etc., which are known to give a unique effect of forest incense.

In particular, according to a preferred embodiment of the present invention, among the conifer extracts, the pine pine extract calms the central nervous system and gives a pleasant feeling, and helps to extend the sleep time and take a comfortable sleep. In addition, pine pine extract has a strong antibacterial effect that does not cause resistance in the human body, and the natural substance pine pine extract has a house dust mite repellent effect of up to 90%, so there are no side effects and it is very effective in preventing allergies.

In the present invention, while conducting continuous research to verify whether various substances have a deep sleep effect, it was found that alpha-pinene contained in pine pine extract had a sedative effect when administered to experimental mice. However, it is surprising that although alpha-pinene has a sedative effect at a low concentration, for example, about 25-80 mg/kg, the effect of improving sleep is significantly superior at a high concentration of about 100 mg/kg or more. confirmed

As such, according to a preferred embodiment of the present invention, it was confirmed that the sleep improvement effect was very excellent in the conifer extract containing alpha pinene, and more preferably, the pine pine extract was significantly superior.

According to a preferred embodiment of the present invention, the coniferous extract of the present invention may be used as a component obtained by extraction using any one of immature conifers, mature conifers, leaves, branches, roots, and bark. More specifically, it contains various physiologically active substances such as alpha-pinene, beta-pinene, di-limonene, 3-carene, etc. as a component obtained using conifers, and reduces stress from free radicals, eliminates insomnia, or improves sleep quality. There is a function.

According to a preferred embodiment of the present invention, the sleep improvement effect of the conifer extract has the effect of increasing the amount of sleep without impairing sleep intensity by, for example, extending the sleep duration, improving the quality of sleep, Sleep disorders can be prevented or treated.

The conifer extract of the present invention has been confirmed to be superior to zolpidem, which is widely known for sleep improvement or treatment of sleep disorders, and unlike existing drugs, since it is a natural material, it is associated with improved sleep, sleep disorders or unstable life, reduced concentration, etc. without side effects. It is confirmed that it can be very preferably applied to the prevention and treatment of diseases.

According to a preferred embodiment of the present invention, as a composition capable of inducing quality sleep and improving sleep disorders or anxiety, a natural material for improving sleep containing a conifer extract containing alpha pinene is supported on a porous molded body for sustained release. It is possible to provide a scent diffusing body that induces scent diffusing.

According to a preferred embodiment of the present invention, the content ratio of the porous molded body and the conifer extract helpful for improving sleep may affect the loading rate and molding stability. Specifically, if the weight ratio of the conifer extract helpful for sleep improvement is excessively increased, the loading rate may be lowered because the concentration that can be accommodated by the porous molded body, which is the main material to be supported, is exceeded. When the content ratio of the extract is too small, although the fragrance effect is insignificant, the bonding force with the fine particles or microparticles constituting the porous molded body is weakened, so that the fragrance is quickly consumed.

Therefore, according to a preferred embodiment of the present invention, it may be preferable that the weight ratio of the conifer extract useful for sleep improvement and the porous molded body is 2:8 to 4:6.

According to a preferred embodiment of the present invention, the porous particles constituting the porous molded article may include at least one selected from the group consisting of silica, zeolite, activated carbon and acrylic resin particles, starch, tapioca starch, dextrin, and modified dextrin. have. For example, beta-cyclodextrin may be included.

According to a preferred embodiment of the present invention, the porous molded body preferably uses a material harmless to the human body and the environment, and may further include an additional carrier.

According to a preferred embodiment of the present invention, due to the configuration of the porous molded body, the conifer extract, which helps to improve sleep, can be stably supported without alteration of its inherent odor. In addition, the porous molded body may serve to prevent denaturation of the scent inherent in the conifer extract by gradually releasing the supported conifer extract to help improve sleep.

Further, according to a preferred embodiment of the present invention, in order to improve the loading rate of the conifer extract supported on the porous molded body, the porosity of the porous molded body is, for example, 70% or more, for example, 80% or more, for example, 90%. can

According to a preferred embodiment of the present invention, the present invention is a fragrance treatment product for improving sleep having conditions of natural scent, and a sleep aid product composed of a scent-healing agent for patients with delayed sleep phase syndrome or depression and insomnia. can be provided as

According to a preferred embodiment of the present invention, the fragrance may contain 0.01 to 80% by weight of the conifer extract.

According to a preferred embodiment of the present invention, the conifer extract may additionally contain aromatic essential oil or essential oil, for example, an extract using an aqueous solvent.

According to a preferred embodiment of the present invention, specific examples of essential oil types include lavender, grapefruit, geranium, cinnamon leaf, tea tree, cedarwood, orange, eucalyptus, bergamot. , lemon, lime, mandarin, myrrh, neroli, niaouli, peppermint, pine, rosemary, chamomile, ylang-ylang, neem, frankincence, benzo Including oil obtained from at least one selected from the group consisting of benzoin, helichrysum, phytoncide, conifer extract, cypress extract, pine conifer oil, rosewood, sandalwood, etc. can do.

Further, according to a preferred embodiment of the present invention, the conifer extract may further include a solvent and an additive, and the solvent may include ethanol, water, glycerin, silicone oil, etc., and further include an additive such as color. can do.

The conifer extract used in the present invention is not limited to the main fragrance substances described above, and may include, but is not limited to, common vegetable oils, and other solvents and additives generally used for fragrance are not particularly limited and may include. have.

According to a preferred embodiment of the present invention, when the method of manufacturing the solid type fragrance therapy product for improving sleep of the present invention is described as an example,

1) mixing porous particles with coniferous extracts that help improve sleep;

2) injecting the mixture of 1) into the casting, cooling and high pressure to form a molded body in which the conifer extract is supported on the porous molded body.

According to a preferred embodiment of the present invention, in the method for manufacturing a solid type fragrance treatment product for sleep improvement of the present invention according to the above method, the conifer extract helpful for sleep improvement is uniformly distributed in the porous particles composed of the porous molded body It may have a structured structure.

In addition, the present invention can provide a solid type scent treatment product for sleep improvement having a sustained release type by loading a conifer extract helpful for sleep improvement in the pores of the porous particles, improving the durability of the scent, and altering the early odor can prevent

In the present invention, instead of inserting a liquid or gel-like material into a selectively gas permeable membrane film, sheet or matrix having breathability and water resistance, it is possible to allow only gas to permeate through the small pores of the membrane and be emitted.

According to a preferred embodiment of the present invention, as the selective gas permeable membrane film, sheet, matrix, etc. having the ventilation and waterproof properties, conventionally developed products may be used.

According to a preferred embodiment of the present invention, it contains, for example, 30 to 80% by weight of a gel, 0.01 to 20% by weight of a coniferous extract, and 5 to 20% by weight of purified water, and is in the form of a jelly or gel at room temperature of 20 to 25 ℃ for 60 days or more Since it can be sustainable, it can be manufactured as a sleep-improving fragrance that can maintain optimal deep sleep.

According to another aspect of the present invention a) mixing the gel phase and purified water; b) mixing the coniferous extract with the mixture of step a); c) It can be prepared as a sleep improvement fragrance treatment product comprising the step of putting the mixture prepared through steps a)-b) in a sealed container to form a gel or jelly.

If the gel phase is less than 30% by weight, it may be difficult to form a gel or jelly phase in a semi-liquid state.

According to a preferred embodiment of the present invention, the gel or jelly phase may be one or more selected from the group consisting of starch, tapioca, mung bean, potato, sweet potato, corn, cellulose, CMC, carbomer, carrageenan, KEPCO and gelatin, gellan gum. More specifically, a carbomer is preferred.

According to the present invention, the carbomer can be used as a gelling agent. The gelling agent generally refers to a substance or composition that changes a liquid into a semi-solid gel when mixed with a liquid. Most gelatinous products use gelatin or gellan gum as a gelling agent. However, in the case of the gelatinized product or gellan gum, when a certain period of time has elapsed at room temperature, the gel volatilizes and contracts, and the shape is distorted or cannot be maintained in its initial form. In addition, the gelatin or gellan gum product has a disadvantage in that stability in terms of durability is poor because the gel volatilizes rapidly at a high temperature of 40° C. or more.

On the other hand, the gelatin has a disadvantage in that the production cost is increased because a process of alkali or acid treatment of cow or pork skin is added.

The purified water is used as a solvent and is used to uniformly mix and form a gel of each of the above-described compositions.

According to a preferred embodiment of the present invention, when the amount of the conifer extract is less than 0.01% by weight, fragrance treatment is impossible because it does not smell, and when it exceeds 20% by weight, the oil cannot be mixed with the gel-like compositions and separation of the oil may occur.

Hereinafter, the gel or jelly phase according to an embodiment of the present invention can be replaced after a cycle of 60 days, and a fragrance treatment product for improving sleep that can maintain optimal sleep will be described in detail.

However, the present invention may be embodied in several different forms and is not limited to the embodiments described herein.

(1) First mixing step

First, a first mixture is prepared by mixing the gel phase or the jelly phase with purified water. In one embodiment, the first mixture may contain 30 to 80% by weight of a gel or jelly, and 5 to 20% by weight of purified water. The gel phase may be one or more selected from the group consisting of starch, tapioca, mung bean, potato, sweet potato, corn, cellulose, CMC, carbomer, carrageenan, KEPCO and gelatin, and gellan gum. More specifically, a carbomer is preferred.

In another embodiment, the carbomer may be uniformly dispersed in purified water in the form of a powder. In order to uniformly disperse the carbomer in the gel or jellied composition, the carbomer is introduced at the initial stage of the manufacturing step of the gel or jelly-like fragrance therapy product for improving sleep.

In this step, the first mixture is prepared by mixing for a time of 30 minutes or more and 60 minutes or less at a speed of 20 rpm or more and 60 rpm or less using a known stirrer. If the speed of the stirrer is less than 20 rpm, the first mixture may not be uniformly mixed and agglomeration may occur in which some powders form lumps. On the other hand, when the speed of the stirrer exceeds 60 rpm, the gel-like or jelly-like phenomenon may be hardened.

In addition, if it is less than 30 minutes, separation may occur after a long time in the mixed state, and if it exceeds 60 minutes, the conifer extract may be lost due to frictional heat during stirring.

(2) second mixing step

It is prepared by adding a conifer extract to the first mixture. The conifer extract contains 0.01 to 20% by weight. The conifer extract uses an extract extracted using by-products such as immature conifers, mature conifers, branches, and leaves. More specifically, mature conifers are preferable.

(3) gelation step

Next, it is a step of terminating the mixing process of the second mixture to form a gel or jelly. In one embodiment, after each of the steps described above, the second mixture is placed in a container, the selective gas-permeable membrane is hot-pressed, and the silver foil wrapping paper is thermally bonded on all sides to obtain a gel-like or jelly-like scent treatment product for improving sleep. The sealing of the container is to prevent the coniferous extract from flying off while the second mixture becomes a gel or a jelly.

Example 1

It relates to a fragrance therapy product for improving sleep in gel or jelly form containing carbomer.

First, a first mixture was prepared by mixing carbomer and purified water. In one embodiment, 80% by weight of the carbomer was used, and 19% by weight of purified water was used.

Next, the conifer extract was added to the first mixture and mixed at 60 rpm for 30 minutes using a stirrer to prepare a second mixture. In one embodiment, 1 wt% of the conifer extract was used.

The second mixture is placed in a sealed container and stored at room temperature for one day, and finally, a gel or jelly-like fragrance therapy product for improving sleep containing carbomer is completed.

Example 2

In order to produce a fragrance therapy product for sleep improvement with a solid natural fragrance containing conifer extract that helps to improve sleep, first, porous particles beta-cyclodextrin and conifer extract are mixed in a 2:8 ratio and then sieved. After making it homogeneous using a tablet press, tablets were prepared.

Test Example: Measurement of sleep effect of pine pine extract sleep improvement composition material

In order to objectively evaluate the sound sleep effect of the pine pine extract (conifer extract with pine nuts removed) sleep improvement composition material according to the present invention, using the pine pine extract sleep improvement composition material prepared in Table 1 above, EEG, safety level during sleep , an electrocardiogram was measured to conduct polysomnography and subjective evaluation of sleep. The specific method is as follows.

1. Subject

The subjects of the study were 200 women in their 10s to 40s who were healthy, currently not taking drugs, and were not intoxicated.

Subjects were instructed to refrain from excessive exercise or excessive drinking on the day before the experiment, and to refrain from smoking, beverages, drugs, and gum that could affect the central nervous system and sense of smell on the day of the experiment. As an experiment targeting adult women, it was reported that there is a correlation between changes in the sense of smell according to a woman's sexual cycle, and a woman's menstrual cycle and mood.

2. Experimental sample

As a comparative example, a non-scented condition and pine pine extract sleep improvement composition material were used as comparative examples. A constant scent was presented to the sleep laboratory, and polysomnography was performed by measuring brain waves (EEG), safety level (EOG), and electrocardiogram (ECG) during sleep.

3. Experiment site

The experiment was carried out in the sleep laboratory (4.8 m x 3 m x 2.4 m) built by the Institute of Standards and Science, and a soundproof device is installed inside to exclude the influence of the external environment during the experiment. In the sleep laboratory, constant temperature and constant humidity were maintained, and the temperature was 24 ℃ and the humidity was 40%.

4. Measurement method

For physiological signals during sleep, electroencephalogram (EEG), safety level (EOG), and electrocardiogram (ECG) were measured using a polysomnography device. Subjective evaluation of sleep was to be written after the experiment was completed with respect to the sleep felt by the subjects.

5. Experiment sequence

The polysomnography test was conducted three times under the conditions of the control example and the example.

In order to exclude the effect on sleep, samples were randomly conducted for each subject, and before this experiment, they were asked to sleep in the sleep laboratory 1 to 2 times in order to adapt to the sleep laboratory. The sleep time was to be taken for 2 hours during the day, and each subject was to sleep at the same time. In addition, subjective evaluation of sleep after sleep was collected through questionnaire.

6. Analysis method

While the subject was sleeping, physiological signals were measured using a polysomnography device, and sleep stages were analyzed using the measured signals. The sleep stage was determined using the international standard method of Rechtschaffen and Kales (1968).

Using the divided sleep stages, sleep latency and sleep efficiency were compared. In addition, after sleeping under the given conditions, subjective feelings were collected through a questionnaire and statistical analysis was performed using the t-test using the SPSS program.

7. Experimental results

go. sleep latency

Condition control group 1 control group 2 control group 3 Experimental group 1 Experimental group 2 Experimental group 3 Elevation delay time average value (minutes) 35.12 34.89 35.77 29.21 29.45 29.33

As can be seen in Table 1 and FIG. 1, the average of the elevation delay time was shorter in the experimental group containing the pine tree extract than in the control group not containing the pine pine extract, which means that the experimental group containing the pine nut extract returned to sleep within a short time. means to lift

me. sleep efficiency

Sleep efficiency is the ratio of total sleep time to time in bed, and the ratio of sleep time during the experimental period was compared.

The results for the sleep efficiency are shown in Table 2 and FIG. 2 below.

Condition control group 1 control group 2 control group 3 Experimental group 1 Experimental group 2 Experimental group 3 Sleep efficiency (%) 55.40 56.22 55.20 63.70 63.0 63.2

As can be seen in Table 2 and FIG. 2, when looking at the average of sleep efficiency, the experimental group containing the pine tree extract had higher sleep efficiency than the control group, which was a longer time than when the experimental group containing the pine tree extract had no fragrance. means to go to sleep while

All. subjective evaluation

① level of tension

Table 3 and FIG. 3 are charts showing the degree of tension during sleep compared to normal sleep.

Condition control group 1 control group 2 control group 3 Experimental group 1 Experimental group 2 Experimental group 3 Tension level compared to usual (points) 0.92 0.65 0.52 1.12 1.04 1.17

As can be seen in Table 3 and FIG. 3, the average sleep efficiency was higher in the experimental group including the pine nut extract sleep improvement composition material than in the control group, which was found in the experimental example containing the pine pine extract sleep improvement composition material. It means going to sleep for a longer period of time than when you are not.

② Degree of tossing

Table 4 and Figure 4 below are charts showing the degree of tossing and turning during sleep compared to usual.

Condition control group 1 control group 2 control group 3 Experimental group 1 Experimental group 2 Experimental group 3 Degree of tossing and turning compared to usual (points) -0.14 -0.20 -0.18 0.85 0.88 0.84

As can be seen in Table 4 and FIG. 4, in the control condition, they answered that they tossed and turned more than usual, and in the experimental group conditions, they answered that they tossed and turned less than usual.

③ Overall sleep level

Table 5 and FIG. 5 are charts showing the overall feeling of sleep compared to usual.

Condition control group 1 control group 2 control group 3 Experimental group 1 Experimental group 2 Experimental group 3 Overall sleep satisfaction (points) 0.32 0.52 0.48 0.96 0.94 0.97

As can be seen in Table 5 and FIG. 5, in the control condition, a similar level of sleep was taken compared to usual, but in the experimental group condition, it was answered that they had a good sleep as usual. Sleep satisfaction was found to be very good.

Claims (8)

A fragrance for improving sleep containing natural ingredients, comprising a composition for improving sleep or preventing and improving diseases or symptoms related to sleep disorders, containing a conifer extract as an active ingredient, in a porous molded body. [Claim 2] The fragrance for improving sleep containing natural ingredients according to claim 1, wherein the porous molded body is made of a membrane film, sheet or matrix having small pores having air permeability and selective gas permeability having breathability and waterproof properties. The fragrance for improving sleep containing natural ingredients according to claim 2, wherein the membrane film, sheet or matrix is thermally bonded in a cylindrical or tetrahedral shape. The method according to claim 1, wherein the porous molded body is a powder, porous particles, granules, pellets, microspheres, or powder having small pores in the form of tablets made by tableting in a state of maintaining the pores, the natural ingredient-containing perfume for improving sleep. The method according to claim 1, wherein the scent scenting body contains a natural ingredient-containing scent scenting body for improving sleep in which the conifer extract is supported in the pores of the porous molded body so that the active ingredient for improving sleep is released from the conifer extract in a sustained-release manner. The method according to claim 1, wherein the porous molded body is made of any one or more of wood, fiber, and synthetic resin harmless to the human body and the environment. The method according to claim 1, wherein the porous molded body further comprises a support or is formed in a three-dimensional skeletal structure containing a natural ingredient-containing fragrance for improving sleep. The method according to claim 1, wherein the scent scenting body contains a natural ingredient containing a conifer extract in an amount of 0.01 to 80% by weight.

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