KR102512899B1 - 고형 종양의 치료를 위한 투약 요법 - Google Patents
고형 종양의 치료를 위한 투약 요법 Download PDFInfo
- Publication number
- KR102512899B1 KR102512899B1 KR1020197005847A KR20197005847A KR102512899B1 KR 102512899 B1 KR102512899 B1 KR 102512899B1 KR 1020197005847 A KR1020197005847 A KR 1020197005847A KR 20197005847 A KR20197005847 A KR 20197005847A KR 102512899 B1 KR102512899 B1 KR 102512899B1
- Authority
- KR
- South Korea
- Prior art keywords
- cancer
- dose
- pharmaceutical composition
- day
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381911P | 2016-08-31 | 2016-08-31 | |
| US62/381,911 | 2016-08-31 | ||
| PCT/US2017/048308 WO2018044662A1 (en) | 2016-08-31 | 2017-08-24 | Dosage regimen for treatment of solid tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190042591A KR20190042591A (ko) | 2019-04-24 |
| KR102512899B1 true KR102512899B1 (ko) | 2023-03-23 |
Family
ID=59772787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197005847A Active KR102512899B1 (ko) | 2016-08-31 | 2017-08-24 | 고형 종양의 치료를 위한 투약 요법 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190209581A1 (enExample) |
| EP (1) | EP3506905B1 (enExample) |
| JP (2) | JP2019526632A (enExample) |
| KR (1) | KR102512899B1 (enExample) |
| CN (2) | CN109562114A (enExample) |
| AU (1) | AU2017321011B2 (enExample) |
| BR (1) | BR112019002461A2 (enExample) |
| CA (1) | CA3035616A1 (enExample) |
| ES (1) | ES2977556T3 (enExample) |
| IL (2) | IL305136A (enExample) |
| MA (1) | MA46086A (enExample) |
| MX (1) | MX387397B (enExample) |
| SG (2) | SG10202107832UA (enExample) |
| WO (1) | WO2018044662A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI609687B (zh) | 2015-04-14 | 2018-01-01 | 美國禮來大藥廠 | 平滑肌肉瘤之標靶性治療 |
| RU2754452C2 (ru) | 2016-04-12 | 2021-09-02 | Эли Лилли Энд Компани | Комбинированная терапия ингибиторами notch и pi3k/mtor для применения в лечении рака |
| ES2881801T3 (es) | 2016-04-12 | 2021-11-30 | Lilly Co Eli | Terapia de combinación con inhibidores de Notch y CDK4/6 para su uso en el tratamiento de cáncer de pulmón |
| KR102463617B1 (ko) | 2016-05-20 | 2022-11-03 | 일라이 릴리 앤드 캄파니 | Notch 및 PD-1 또는 PD-L1 억제제를 이용한 조합 요법 |
| EP3525796A1 (en) | 2016-10-12 | 2019-08-21 | Eli Lilly and Company | Targeted treatment of mature t-cell lymphoma |
| SG11201907580SA (en) | 2017-02-17 | 2019-09-27 | Hutchinson Fred Cancer Res | Combination therapies for treatment of bcma-related cancers and autoimmune disorders |
| AU2018359907A1 (en) | 2017-11-06 | 2020-05-07 | Fred Hutchinson Cancer Center | Combination of a cell therapy and a gamma secretase inhibitor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014527042A (ja) * | 2011-07-27 | 2014-10-09 | イーライ リリー アンド カンパニー | ノッチ経路シグナリングインヒビター化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US46206A (en) | 1865-02-07 | Improved vessel for holding petroleum | ||
| WO2008112249A1 (en) * | 2007-03-13 | 2008-09-18 | Trustees Of Columbia University In The City Of New York | Synergistic interaction of notch-1 inhibitors with glucocorticoids |
| KR101245604B1 (ko) * | 2007-11-13 | 2013-03-21 | 메리테이지 파마, 인크. | 코르티코스테로이드 조성물 |
| KR20170029490A (ko) * | 2014-07-11 | 2017-03-15 | 제넨테크, 인크. | 노치 경로 억제 |
| TWI609687B (zh) * | 2015-04-14 | 2018-01-01 | 美國禮來大藥廠 | 平滑肌肉瘤之標靶性治療 |
-
2017
- 2017-08-24 SG SG10202107832UA patent/SG10202107832UA/en unknown
- 2017-08-24 CA CA3035616A patent/CA3035616A1/en active Pending
- 2017-08-24 WO PCT/US2017/048308 patent/WO2018044662A1/en not_active Ceased
- 2017-08-24 KR KR1020197005847A patent/KR102512899B1/ko active Active
- 2017-08-24 IL IL305136A patent/IL305136A/en unknown
- 2017-08-24 MX MX2019002066A patent/MX387397B/es unknown
- 2017-08-24 SG SG11201901325UA patent/SG11201901325UA/en unknown
- 2017-08-24 IL IL264924A patent/IL264924B2/en unknown
- 2017-08-24 AU AU2017321011A patent/AU2017321011B2/en active Active
- 2017-08-24 MA MA046086A patent/MA46086A/fr unknown
- 2017-08-24 US US16/328,267 patent/US20190209581A1/en not_active Abandoned
- 2017-08-24 CN CN201780052146.2A patent/CN109562114A/zh active Pending
- 2017-08-24 ES ES17761723T patent/ES2977556T3/es active Active
- 2017-08-24 CN CN202310314953.4A patent/CN116473978A/zh active Pending
- 2017-08-24 BR BR112019002461A patent/BR112019002461A2/pt not_active Application Discontinuation
- 2017-08-24 EP EP17761723.0A patent/EP3506905B1/en active Active
- 2017-08-24 JP JP2019531873A patent/JP2019526632A/ja active Pending
-
2022
- 2022-12-27 JP JP2022209634A patent/JP2023052108A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014527042A (ja) * | 2011-07-27 | 2014-10-09 | イーライ リリー アンド カンパニー | ノッチ経路シグナリングインヒビター化合物 |
Non-Patent Citations (1)
| Title |
|---|
| Journal of Clinical Oncology, 2015년, 33 (15 suppl), p.2533-2533 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023052108A (ja) | 2023-04-11 |
| MX387397B (es) | 2025-03-18 |
| IL264924B1 (en) | 2023-09-01 |
| MA46086A (fr) | 2019-07-10 |
| IL305136A (en) | 2023-10-01 |
| AU2017321011A1 (en) | 2019-02-21 |
| US20190209581A1 (en) | 2019-07-11 |
| CN109562114A (zh) | 2019-04-02 |
| WO2018044662A1 (en) | 2018-03-08 |
| CA3035616A1 (en) | 2018-03-08 |
| ES2977556T3 (es) | 2024-08-26 |
| BR112019002461A2 (pt) | 2019-05-14 |
| EP3506905B1 (en) | 2024-03-20 |
| IL264924A (enExample) | 2019-04-30 |
| JP2019526632A (ja) | 2019-09-19 |
| AU2017321011B2 (en) | 2023-08-03 |
| EP3506905A1 (en) | 2019-07-10 |
| SG11201901325UA (en) | 2019-03-28 |
| IL264924B2 (en) | 2024-01-01 |
| KR20190042591A (ko) | 2019-04-24 |
| MX2019002066A (es) | 2019-06-03 |
| CN116473978A (zh) | 2023-07-25 |
| SG10202107832UA (en) | 2021-09-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |