KR102491439B1 - 아비라테론 아세테이트 제제 및 사용 방법 - Google Patents

아비라테론 아세테이트 제제 및 사용 방법 Download PDF

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KR102491439B1
KR102491439B1 KR1020177008938A KR20177008938A KR102491439B1 KR 102491439 B1 KR102491439 B1 KR 102491439B1 KR 1020177008938 A KR1020177008938 A KR 1020177008938A KR 20177008938 A KR20177008938 A KR 20177008938A KR 102491439 B1 KR102491439 B1 KR 102491439B1
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abiraterone acetate
dosage form
unit dosage
dose
sodium
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English (en)
Korean (ko)
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KR20170070025A (ko
Inventor
마우라 머피
폴 네메스
에이치. 윌리엄 보쉬
매튜 칼라한
사티야 바미디파티
제이슨 콜먼
크리스토퍼 힐
마르크 노렛
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썬 파마슈티칼 인더스트리스 리미티드
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Priority claimed from US14/707,922 external-priority patent/US20150246060A1/en
Application filed by 썬 파마슈티칼 인더스트리스 리미티드 filed Critical 썬 파마슈티칼 인더스트리스 리미티드
Priority to KR1020237001893A priority Critical patent/KR102617537B1/ko
Publication of KR20170070025A publication Critical patent/KR20170070025A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
KR1020177008938A 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법 Active KR102491439B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237001893A KR102617537B1 (ko) 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462052294P 2014-09-18 2014-09-18
US62/052,294 2014-09-18
US14/707,922 US20150246060A1 (en) 2013-03-15 2015-05-08 Abiraterone Acetate Formulation and Methods of Use
US14/707,922 2015-05-08
PCT/US2015/050889 WO2016044701A1 (en) 2014-09-18 2015-09-18 Abiraterone acetate formulation and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020237001893A Division KR102617537B1 (ko) 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법

Publications (2)

Publication Number Publication Date
KR20170070025A KR20170070025A (ko) 2017-06-21
KR102491439B1 true KR102491439B1 (ko) 2023-01-25

Family

ID=55533897

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020237001893A Active KR102617537B1 (ko) 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법
KR1020177008938A Active KR102491439B1 (ko) 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법

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KR1020237001893A Active KR102617537B1 (ko) 2014-09-18 2015-09-18 아비라테론 아세테이트 제제 및 사용 방법

Country Status (17)

Country Link
EP (1) EP3193857A4 (enrdf_load_stackoverflow)
JP (1) JP2017528457A (enrdf_load_stackoverflow)
KR (2) KR102617537B1 (enrdf_load_stackoverflow)
CN (1) CN106687112A (enrdf_load_stackoverflow)
AP (1) AP2017009804A0 (enrdf_load_stackoverflow)
AU (1) AU2015317466A1 (enrdf_load_stackoverflow)
BR (1) BR112017003219A2 (enrdf_load_stackoverflow)
CA (1) CA2958316A1 (enrdf_load_stackoverflow)
CO (1) CO2017002472A2 (enrdf_load_stackoverflow)
EA (1) EA201790650A1 (enrdf_load_stackoverflow)
IL (1) IL250270B (enrdf_load_stackoverflow)
MD (1) MD20170048A2 (enrdf_load_stackoverflow)
MX (1) MX2017003525A (enrdf_load_stackoverflow)
PH (1) PH12017500239A1 (enrdf_load_stackoverflow)
SG (1) SG11201701139YA (enrdf_load_stackoverflow)
TN (2) TN2017000098A1 (enrdf_load_stackoverflow)
WO (1) WO2016044701A1 (enrdf_load_stackoverflow)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3280448B1 (en) 2015-04-10 2020-12-30 Capsugel Belgium NV Abiraterone acetate lipid formulations
CN110891549A (zh) 2017-04-07 2020-03-17 玛亚实验室公司 改善治疗剂的溶解度和生物利用度的方法
CN113473974A (zh) * 2019-01-25 2021-10-01 深圳市药欣生物科技有限公司 药物组合物
CA3131034A1 (en) 2019-03-06 2020-09-10 Matthew J. Sharp Abiraterone prodrugs
CN110742870B (zh) * 2019-12-04 2021-04-20 武汉大学 醋酸阿比特龙制剂及其制备方法
CN111110646A (zh) * 2020-02-19 2020-05-08 纳兰迦(上海)生物医药科技有限公司 一种低规格醋酸阿比特龙口服制剂的处方及制备方法
CN113384542B (zh) * 2020-03-14 2024-03-29 鲁南制药集团股份有限公司 一种甾体cyp17抑制剂固体分散体的片剂及其制备方法
KR20220166856A (ko) * 2020-04-16 2022-12-19 타반타 테라퓨틱스 헝가리 인코포레이티드 전립선암을 치료하기 위한 방법 및 조성물
CA3177094A1 (en) * 2020-05-08 2021-11-11 Janssen Pharmaceutica Nv Treatment of prostate cancer with a combination of abiraterone acetate and niraparib
EP3944860A1 (en) 2020-07-30 2022-02-02 Galenicum Health S.L.U. Abiraterone for use in a method of treating cancer
CA3207282A1 (en) 2021-02-15 2022-08-18 Matthew J. Sharp Abiraterone prodrugs
KR20240044329A (ko) 2022-09-28 2024-04-04 한미약품 주식회사 아비라테론 아세테이트 및 프레드니솔론을 포함하는 경구용 복합정제
KR20240145412A (ko) 2023-03-27 2024-10-07 한미약품 주식회사 아비라테론 아세테이트 및 프레드니솔론을 포함하는 약제학적 제제 및 이의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102743393A (zh) 2012-07-27 2012-10-24 海南盛科生命科学研究院 一种含有醋酸阿比特龙的药物组合物及制备工艺
WO2014009436A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Nanosuspension of abiraterone acetate
WO2014009434A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Self-microemulsifying drug delivery system of abiraterone or abiraterone acetate
WO2014145813A1 (en) 2013-03-15 2014-09-18 Iceutica Inc. Abiraterone acetate formulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6141013B2 (ja) * 2009-04-24 2017-06-07 イシューティカ ピーティーワイ リミテッド 商業的規模での封入ナノ粒子の製造
GB201207886D0 (en) * 2012-05-04 2012-06-20 Jagotec Ag Improvements in or relating to organic compounds
WO2014009437A1 (en) * 2012-07-11 2014-01-16 Sandoz Ag Oxidation stability of abiraterone acetate

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014009436A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Nanosuspension of abiraterone acetate
WO2014009434A1 (en) 2012-07-11 2014-01-16 Sandoz Ag Self-microemulsifying drug delivery system of abiraterone or abiraterone acetate
CN102743393A (zh) 2012-07-27 2012-10-24 海南盛科生命科学研究院 一种含有醋酸阿比特龙的药物组合物及制备工艺
WO2014145813A1 (en) 2013-03-15 2014-09-18 Iceutica Inc. Abiraterone acetate formulation
KR102121404B1 (ko) 2013-03-15 2020-06-11 썬 파마 글로벌 에프제트이 아비라테론 아세테이트 제제

Also Published As

Publication number Publication date
KR20230014878A (ko) 2023-01-30
TN2017000098A1 (en) 2018-10-19
KR20170070025A (ko) 2017-06-21
KR102617537B1 (ko) 2023-12-22
IL250270A0 (en) 2017-03-30
JP2017528457A (ja) 2017-09-28
IL250270B (en) 2021-02-28
CO2017002472A2 (es) 2017-07-11
EP3193857A4 (en) 2018-04-11
MX2017003525A (es) 2017-06-21
BR112017003219A2 (pt) 2017-11-28
CA2958316A1 (en) 2016-03-24
WO2016044701A1 (en) 2016-03-24
AP2017009804A0 (en) 2017-03-31
AU2015317466A1 (en) 2017-02-23
PH12017500239A1 (en) 2017-07-03
SG11201701139YA (en) 2017-03-30
MD20170048A2 (ro) 2017-08-31
EA201790650A1 (ru) 2017-07-31
CN106687112A (zh) 2017-05-17
EP3193857A1 (en) 2017-07-26
TN2018000318A1 (en) 2020-01-16

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