KR102471879B1 - Chinese medicine for treating children constipation - Google Patents
Chinese medicine for treating children constipation Download PDFInfo
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- KR102471879B1 KR102471879B1 KR1020170127462A KR20170127462A KR102471879B1 KR 102471879 B1 KR102471879 B1 KR 102471879B1 KR 1020170127462 A KR1020170127462 A KR 1020170127462A KR 20170127462 A KR20170127462 A KR 20170127462A KR 102471879 B1 KR102471879 B1 KR 102471879B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Abstract
본 발명은 민들레(Dandlion), 천우슬(Cyathula officinalis), 함소화(Michelia Figo), 소엽맥문동(Ophiopogon japonicus), 인삼(Ginseng), 관동화(Flos farfarae) 및 꿀(Honey)을 포함하는 어린이 변비 치료용 중의약이 개시되어 있다. 본 발명에서 제공된 어린이 변비 치료용 중의약은 어린이 변비 치료를 위한 특수 효과를 가지며, 치유 후 낮은 재발 가능성을 갖는다.The present invention treats constipation in children, including Dandelion, Cyathula officinalis, Michelia Figo, Ophiopogon japonicus, Ginseng, Flos farfarae and Honey. Chinese medicine for use is disclosed. The Chinese medicine for treating constipation in children provided in the present invention has a special effect for treating constipation in children and has a low recurrence possibility after healing.
Description
본 발명은 어린이 변비 치료용 중의약 및 그의 제조 방법에 관한 것이다.The present invention relates to a traditional Chinese medicine for the treatment of constipation in children and a method for preparing the same.
변비는 일반적으로 배변 규칙의 변화에 의하여 야기되며, 마르고 딱딱한 배설물 및 긴 배변 시간 간격 (>2 일)에 의하여 나타나거나 또는 배변 욕구가 있더라도 배설물을 배출하지 못하는 것에 의하여 나타난다. 어린이 변비는 일시적인 유형 또는 고질적인 유형으로 일반적으로 분류되며, 신생아의 경우 최초 태변이 배출될 때의 시점을 기록하여야 한다. 부적합한 식품의 섭식, 불충분한 식품 섭식, 과학적 및 적정한 배변 운동 없음, 장관 윤활제 및 관장에 대한 과의존, 의약의 부작용에 의하여 야기되는 해로운 자극 및 정신적 요인을 포함한 어린이 변비를 초래하는 다수의 요인이 존재한다. 어린이 변비의 임상적 징후는 어린이 환자의 감소된 배변 횟수, 마르고 딱딱한 배설물, 어려운 배변 및 항문 통증, 복부 팽만 및 하복부 둔통, 복명 및 잦은 방귀를 포함한다. 때때로, 배설물은 장 점막 또는 항문에 상처를 주어 출혈을 초래하며, 그리하여 소량의 혈액 또는 점막이 배설물 표면에 존재할 수 있게 된다. 장시간의 변비는 치질 또는 직장의 탈출증을 수반할 수 있다. 장관내에서 배설물의 장시간 체류는 반사적으로 전신 증상, 예를 들면 낙심, 식욕 부진, 허약, 현기증, 두통 등을 야기할 수 있다. 장시간 불충분한 섭취는 영양실조를 초래하여 변비를 더 악화시키며, 악순환을 형성하게 된다. 직장에서 배설물의 장시간 체류는 국소 염증을 야기하여 환자가 중압감을 느끼게 된다. 때때로, 변비를 갖는 어린이 환자는 배변 욕구를 갖지만 한번에 시원하게 배변할 수 없어서 배변 횟수가 증가하게 된다. 심각한 변비에 관하여, 배설물은 국소적으로 영향을 미치며, 장관 분비는 마른 배설물 주위에서 자동적으로 흘러나오게 될 수 있으며, 이는 정확하게는 대변 실금과 같이 된다. 변비는 장 급통증을 야기하는 흔한 원인이 된다. 때때로, 심한 변비를 앓는 어린이는 급성 복통을 겪을 수 있으며, 우선 딱딱한 배설물을 배출한 후, 악취가 풍기는 물변을 배설하며, 그러한 증상을 전통적인 중의약 분야에서는 "레 지에 팡 리우(RE JIE PANG LIU)"로 불리운다.Constipation is usually caused by a change in bowel routine and is manifested by dry, hard faeces and long intervals between bowel movements (>2 days) or by the inability to excrete faeces even when there is a desire to defecate. Constipation in children is generally classified as either a transient type or a chronic type. There are many factors that cause constipation in children, including inadequate food intake, insufficient food intake, lack of scientific and proper bowel movements, over-reliance on enteral lubricants and enemas, harmful stimuli caused by side effects of medications, and psychological factors. do. Clinical signs of constipation in children include reduced stool frequency, dry and hard stools, difficult bowel movements and anal pain, abdominal distension and dull lower abdominal pain, flatulence and frequent farts in children. Occasionally, fecal matter may damage the intestinal mucosa or anus, resulting in bleeding, so that a small amount of blood or mucous membrane may be present on the fecal surface. Prolonged constipation may accompany hemorrhoids or rectal prolapse. Prolonged retention of feces in the intestinal tract can reflexively cause systemic symptoms such as discouragement, anorexia, weakness, dizziness, and headache. Insufficient intake for a long time causes malnutrition, worsens constipation, and forms a vicious cycle. The long stay of excretions in the rectum causes local inflammation, which makes the patient feel burdened. Occasionally, a child patient with constipation has a desire to defecate but cannot defecate coolly at once, resulting in an increase in the frequency of defecation. Regarding severe constipation, the excretion is affected locally, and intestinal secretion can flow out automatically around the dry excrement, which is exactly like fecal incontinence. Constipation is a common cause of intestinal colic. Occasionally, children suffering from severe constipation may experience acute abdominal pain, first excreting hard feces and then excreting foul-smelling watery feces. is called
신체 검사 중에, 복부 고창이 발견될 수 있으며, S상 결장에 잔류하는 배설물 덩어리는 좌측 하부 사분역을 만져서 발견될 수 있으며, 배설물 덩어리는 장 세척을 실시한 후 사라질 것이다. 항문 촉진 검사에 의하면 두껍고 단단한 배설물 덩어리가 직장 변비 환자에 대하여 촉진될 수 있으며, 직장이 비어있을 때 결장 변비가 확실하게 진단된다. 종종, 촉진 검사 후, 다량의 배설물 및 가스가 항문의 팽창시 배출되며, 증상은 그와 함께 사라진 후, 기질적 장 폐색(organic intestinal obstruction)이 배제될 수 있다. 검사자는 배설강 균열(crissum crevice)이 존재하는지의 여부, 국소 피부 감염 및 기저귀 발진이 존재하는지의 여부를 검사하는데 주의를 기울여야 한다. 대변 실금은 속옷이 오염되면서 배설강 및 회음 위치에서 배설물 오염이 있는지를 입증한다. 어린이 환자가 구루병 또는 갑상선 기능저하의 징후를 갖는지의 여부에 대하여 유의하여야 한다.During physical examination, abdominal flatulence may be found, fecal masses remaining in the sigmoid colon may be found by palpation of the left lower quadrant, and fecal masses will disappear after bowel lavage is performed. According to the rectal palpation test, thick and hard excrement masses can be palpated for patients with rectal constipation, and colonic constipation is definitely diagnosed when the rectum is empty. Often, after palpation examination, large amounts of feces and gas are expelled upon dilatation of the anus, and symptoms disappear with it, after which organic intestinal obstruction can be ruled out. The examiner should pay attention to examining whether crissum crevices are present, local skin infections and diaper rash are present. Fecal incontinence demonstrates the presence of fecal contamination in the cloacal and perineal locations with contamination of undergarments. Care should be taken as to whether the child patient has signs of rickets or hypothyroidism.
종래 기술에서, 어린이 변비를 치료하는 통상의 방법은 변비 증상을 일시적으로 완화시키기 위하여 외용 약제, 예컨대 글리세린 관장제를 사용하지만, 이는 변비를 완전하게 없앨 수는 없는 반면, 외용 약제, 예컨대 글리세린 관장제의 장시간 사용은 약제 의존성을 야기할 수 있으며, 심지어 습관성 변비를 초래할 수 있다. 그러므로, 어린이 자신의 배변 능력을 자극시키고, 향상시켜 어린이 변비를 치료하는 기술적 효과를 달성하는 것이 필요하다.In the prior art, conventional methods of treating constipation in children use an external agent, such as a glycerin enema, to temporarily alleviate the symptoms of constipation, but this cannot completely eliminate constipation, while using an external agent, such as a glycerin enema, for a long time. Use can lead to drug dependence and even lead to habitual constipation. Therefore, it is necessary to achieve a technological effect of stimulating and improving children's own defecation ability to treat children's constipation.
본 발명은 어린이 변비를 근절시키며, 우수한 종합적 제약 성질 및 우수한 어린이 변비 치료 효과를 갖는 어린이 변비 치료용 중의약을 제공하는 것을 목적으로 한다. 본 발명에 의한 중의약은 민들레(Dandlion)를 주요 원재료로서 택하여 생성되며, 전통 의약 재료의 효과 및 현대 약리학의 연구 성취를 조합한다.An object of the present invention is to provide a Chinese medicine for treating constipation in children, which eradicates constipation in children, has excellent comprehensive pharmaceutical properties and excellent effects in treating constipation in children. The Chinese medicine according to the present invention is produced by taking dandelion (Dandlion) as the main raw material, and combines the effects of traditional medicinal materials and the research achievements of modern pharmacology.
한 구체예에서, 본 발명은 민들레(Dandlion), 천우슬(Cyathula officinalis), 함소화(Michelia Figo), 소엽맥문동(Ophiopogon japonicus), 인삼(Ginseng), 관동화(Flos farfarae) 및 꿀(Honey)을 포함하는 어린이 변비 치료용 중의약을 제공한다.In one embodiment, the present invention provides dandelion, Cyathula officinalis, Michelia Figo, Ophiopogon japonicus, Ginseng, Flos farfarae and Honey. It provides a Chinese medicine for the treatment of constipation in children comprising.
또 다른 구체예에서, 본 발명은 추가로In another embodiment, the present invention further
민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 해당 비에 따라 혼합하고, 85% 농도의 에틸 알콜을 첨가하고, 50-60℃에서 반복된 초음파 추출을 수행하며, 개개의 추출 용액 모두를 수집하여 추출 용액을 얻는 단계;Dandelion, cheonwooseul, hamsohwa, lobules, ginseng, gwandonghwa and honey were mixed according to the corresponding ratio, 85% concentration ethyl alcohol was added, repeated ultrasonic extraction was carried out at 50-60 ° C, and individual extractions collecting all of the solutions to obtain an extraction solution;
추출 용액을 진공 농축시키고, 건조시켜 고체 연고를 얻는 단계;vacuum concentration of the extraction solution and drying to obtain a solid ointment;
고체 연고를 분쇄시켜 350-400 메쉬의 입자 크기를 갖는 초미세 분말을 얻고, 캡슐 내용물을 얻는 단계;crushing the solid ointment to obtain an ultra-fine powder having a particle size of 350-400 mesh, and obtaining capsule contents;
캡슐 내용물을 캡슐 외피에 포장하여 어린이 변비 치료용 중의약의 완제품을 얻는 단계를 포함하는, 어린이 변비 치료용 중의약의 제조 방법을 제공한다.Provided is a method for manufacturing a Chinese medicine for treating constipation in children, comprising the step of packaging the contents of the capsule in a capsule shell to obtain a finished product of the Chinese medicine for treating constipation in children.
상기 중의약은 하기와 같이 투여된다:The traditional Chinese medicine is administered as follows:
본원에서, 그에 포장된 1 g 캡슐 내용물을 각각 갖는 캡슐은 예로서 경구 투여 방식으로 취한다.Herein, capsules each having a 1 g capsule content packed therein are taken by way of oral administration as an example.
1-3세 어린이의 경우, 캡슐 내용물을 캡슐로부터 꺼내고, 2개의 동일한 부분으로 나누고, 2개의 동일한 부분을 (따뜻한 물에 녹인 후) 아침 식사 후 및 저녁 식사 후 각각 투여한다.For children 1-3 years of age, the contents of the capsule are removed from the capsule, divided into two equal parts, and the two equal parts are administered (after dissolving in warm water) after breakfast and after dinner respectively.
3-4세 어린이의 경우, 1개의 캡슐을 식사 후 1일 1회 투여하며; 어린이가 삼키기 어려울 경우 캡슐 내용물을 캡슐로부터 꺼내고, 소량의 따뜻한 물에 녹인 후 투여한다. 소량의 설탕을 첨가하여 입맛을 좋게 할 수 있다.For children 3-4 years of age, 1 capsule once daily after meals; If it is difficult for children to swallow, take the contents of the capsule out of the capsule, dissolve in a small amount of warm water, and administer. A small amount of sugar can be added to improve the taste.
4-6세 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 1회 투여하며; 어린이가 삼키기 어려울 경우 캡슐 내용물을 캡슐로부터 꺼내고, 소량의 따뜻한 물에 녹인 후 투여한다.For children 4-6 years of age, 1-2 capsules once daily after meals; If it is difficult for children to swallow, take the contents of the capsule out of the capsule, dissolve in a small amount of warm water, and administer.
7-12세 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 2회 투여한다.For children 7-12 years of age, take 1-2 capsules twice daily after meals.
12세가 넘는 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 3회 투여한다.For children over 12 years of age, take 1-2 capsules 3 times daily after meals.
본 발명에서 제공된 어린이 변비 치료용 중의약은 어린이 변비를 치료하기 위한 특수 효과를 가지며, 치유 후 낮은 재발 가능성을 갖는다. 게다가, 본 발명은 추가로 장관을 하제시키는 기술적 효과를 갖는다.The Chinese medicine for treating constipation in children provided in the present invention has a special effect for treating constipation in children and has a low recurrence probability after healing. Besides, the present invention further has the technical effect of laxing the intestinal tract.
본 발명의 기타 특징 및 잇점은 하기 구체적인 실시양태에서 상세하게 기재될 것이다.Other features and advantages of the present invention will be described in detail in the following specific embodiments.
실시양태의 상세한 설명DETAILED DESCRIPTION OF EMBODIMENTS
일반성을 잃지 않으면서, 본 발명은 민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 포함하는 어린이 변비 치료용 중의약을 개시한다.Without loss of generality, the present invention discloses a traditional Chinese medicine for the treatment of constipation in children comprising dandelion, cheonwooseul, hamsohwa, lobulaemamundong, ginseng, guandonghwa and honey.
바람직하게는, 본 발명의 한 바람직한 기술적 해결책에 의하면, 어린이 변비 치료용 중의약은 중량부 기준으로 민들레 20-30, 천우슬 10-20, 함소화 10-20, 소엽맥문동 4-10, 인삼 4-10, 관동화 4-8 및 꿀 3-6을 포함한다.Preferably, according to a preferred technical solution of the present invention, the Chinese medicine for treating constipation in children contains 20-30 dandelion, 10-20 cheonwooseul, 10-20 hamsohwa, 4-10 lobules, 4-10 ginseng, ginseng, based on parts by weight. 10, canton flower 4-8 and honey 3-6.
바람직하게는, 본 발명의 한 바람직한 기술적 해결책에 의하면, 어린이 변비 치료용 중의약은 중량부 기준으로 민들레 25, 천우슬 12, 함소화 11, 소엽맥문동 4, 인삼 4, 관동화 5 및 꿀 4를 포함한다.Preferably, according to a preferred technical solution of the present invention, the traditional Chinese medicine for treating constipation in children comprises 25 parts by weight of dandelion, 12 parts of cheonwooseul, 11 parts of hamsohwa, 4 parts of ginseng, 5 parts of ginseng, and 4 parts of honey. .
바람직하게는, 본 발명의 한 바람직한 기술적 해결책에 의하면, 어린이 변비 치료용 중의약은 중량부 기준으로 민들레 30, 천우슬 18, 함소화 20, 소엽맥문동 9, 인삼 8, 관동화 6 및 꿀 6을 포함한다.Preferably, according to a preferred technical solution of the present invention, the traditional Chinese medicine for treating constipation in children comprises 30 dandelion, 18 cheonwooseul, 20 hamsohwa, 9 ginseng, 8 ginseng, 6 guandong flower and 6 honey. .
본 발명은 또한 민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 해당 비에 따라 혼합하고, 85% 농도의 에틸 알콜을 첨가하고, 50-60℃에서 반복된 초음파 추출을 수행하며, 개개의 추출 용액 모두를 수집하여 추출 용액을 얻는 단계;The present invention also mixes dandelion, cheonwooseul, hamsohwa, lobules, ginseng, gwandonghwa and honey according to the corresponding ratio, adds 85% concentration of ethyl alcohol, and performs repeated ultrasonic extraction at 50-60 ° C. , collecting all of the individual extraction solutions to obtain an extraction solution;
추출 용액을 진공 농축시키고, 건조시켜 고체 연고를 얻는 단계;vacuum concentration of the extraction solution and drying to obtain a solid ointment;
고체 연고를 분쇄시켜 350-400 메쉬의 입자 크기를 갖는 초미세 분말을 얻고, 캡슐 내용물을 얻는 단계;crushing the solid ointment to obtain an ultra-fine powder having a particle size of 350-400 mesh, and obtaining capsule contents;
캡슐 내용물을 캡슐 외피에 포장하여 어린이 변비 치료용 중의약의 완제품을 얻는 단계를 포함하는, 어린이 변비 치료용 중의약의 제조 방법이 개시되어 있다.A method for manufacturing a Chinese medicine for treating constipation in children is disclosed, comprising the step of packaging the contents of the capsule in a capsule shell to obtain a finished product of the Chinese medicine for treating constipation in children.
상기 중의약은 하기와 같이 경구 투여 방식으로 투여된다.The above traditional Chinese medicine is administered by oral administration as follows.
1-3세 어린이의 경우, 캡슐 내용물을 캡슐로부터 꺼내고, 2개의 동일한 부분으로 나누고, 2개의 동일한 부분을 (따뜻한 물에 녹인 후) 아침 식사 후 및 저녁 식사 후 각각 투여한다.For children 1-3 years of age, the contents of the capsule are removed from the capsule, divided into two equal parts, and the two equal parts are administered (after dissolving in warm water) after breakfast and after dinner respectively.
3-4세 어린이의 경우, 1개의 캡슐을 식사 후 1일 1회 투여하며; 어린이가 삼키기 어려울 경우 캡슐 내용물을 캡슐로부터 꺼내고, 소량의 따뜻한 물에 녹인 후 투여한다. 소량의 설탕을 첨가하여 입맛을 좋게 할 수 있다.For children 3-4 years of age, 1 capsule once daily after meals; If it is difficult for children to swallow, take the contents of the capsule out of the capsule, dissolve in a small amount of warm water, and administer. A small amount of sugar can be added to improve the taste.
4-6세 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 1회 투여하며; 어린이가 삼키기 어려울 경우 캡슐 내용물을 캡슐로부터 꺼내고, 소량의 따뜻한 물에 녹인 후 투여한다.For children 4-6 years of age, 1-2 capsules once daily after meals; If it is difficult for children to swallow, take the contents of the capsule out of the capsule, dissolve in a small amount of warm water, and administer.
7-12세 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 2회 투여한다.For children 7-12 years of age, take 1-2 capsules twice daily after meals.
12세가 넘는 어린이의 경우, 1-2개의 캡슐을 식사 후 1일 3회 투여한다.For children over 12 years of age, take 1-2 capsules 3 times daily after meals.
본 발명에서 제공된 어린이 변비 치료용 중의약은 어린이 변비를 치료하기 위한 특수 효과를 가지며, 치유 후 낮은 재발 가능성을 갖는다. 게다가, 본 발명은 추가로 장관을 하제시키는 기술적 효과를 갖는다.The Chinese medicine for treating constipation in children provided in the present invention has a special effect for treating constipation in children and has a low recurrence probability after healing. Besides, the present invention further has the technical effect of laxing the intestinal tract.
하기에서, 본 발명은 실시예를 통하여 보다 상세하게 기재될 것이다.In the following, the present invention will be described in more detail through examples.
실시예Example 1 One
적정한 배변이 없어서 야기되는 변비를 갖는 1세 미만의 어린이의 치료를 수행하였다:Treatment of children under 1 year of age with constipation caused by lack of adequate defecation was performed:
민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 어린이 변비 치료용 중의약의 제조를 위하여 하기 비에 따라 혼합하였다: 민들레 25, 천우슬 12, 함소화 11, 소엽맥문동 4, 인삼 4, 관동화 5 및 꿀 4. 어린이 변비 치료용 중의약의 제조 방법 및 투여 방법은 상기와 동일하다.Dandelion, Cheonwooseul, Hamsohwa, Soyeopmaekmundong, Ginseng, Kwandonghwa and honey were mixed according to the following ratio for the preparation of Chinese medicine for the treatment of constipation in children: Dandelion 25, Cheonwooseul 12, Hamsohwa 11, Lobemaekmundong 4, Ginseng 4 , Guandonghua 5 and honey 4. The manufacturing method and administration method of Chinese medicine for the treatment of constipation in children are the same as above.
중의약의 연속 투여의 2일 후, 변비 증상은 크게 완화되었으며, 배설물의 굳은 정도는 크게 완화되었으며, 중의약의 연속 투여의 또 다른 3일 후, 변비는 완전하게 제거되었다.After 2 days of continuous administration of Chinese medicine, the symptoms of constipation were greatly alleviated, the hardness of feces was greatly alleviated, and after another 3 days of continuous administration of Chinese medicine, constipation was completely eliminated.
실시예Example 2 2
부적절한 섭취에 의하여 야기된 변비를 갖는 2-3세 어린이의 치료:Treatment of children aged 2-3 years with constipation caused by inadequate intake:
민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 어린이 변비 치료용 중의약의 제조를 위하여 하기 비에 따라 혼합하였다: 민들레 30, 천우슬 18, 함소화 20, 소엽맥문동 9, 인삼 8, 관동화 6 및 꿀 6. 어린이 변비 치료용 중의약의 제조 방법 및 투여 방법은 상기와 동일하다.Dandelion, Cheonwooseul, Hamsohwa, Soyeopmaekmundong, Ginseng, Guandonghwa and honey were mixed according to the following ratio for the preparation of Chinese medicine for the treatment of constipation in children: Dandelion 30, Cheonwooseul 18, Hamsohwa 20, Lobemaekmundong 9, Ginseng 8 , Guan Donghua 6 and Honey 6. The manufacturing method and administration method of Chinese medicine for the treatment of constipation in children are the same as above.
중의약의 연속 투여 3일 후 변비 증상은 크게 완화되었으며, 배설물의 굳은 정도는 크게 완화되었으며, 중의약의 연속 투여의 또 다른 5일 후 변비는 완전하게 제거되었다. 어린이 변비 환자의 식사 습관은 회복 후 1개월 이내에 조절되어야만 하며, 즉 어린이는 식이요법을 따라야 하거나 또는 소화가 잘 안되는 식품을 섭취하지 않아야 한다.After 3 days of continuous administration of Chinese medicine, the symptoms of constipation were greatly alleviated, the hardness of excreta was greatly alleviated, and after another 5 days of continuous administration of Chinese medicine, constipation was completely eliminated. The eating habits of children constipated patients must be adjusted within one month after recovery, that is, children must follow a diet or not eat poorly digestible foods.
실시예Example 3 3
습관적인 변비를 갖는 4-6세 어린이의 치료:Treatment of children aged 4-6 years with habitual constipation:
민들레, 천우슬, 함소화, 소엽맥문동, 인삼, 관동화 및 꿀을 어린이 변비 치료용 중의약의 제조를 위하여 하기 비에 따라 혼합하였다: 민들레 25, 천우슬 15, 함소화 15, 소엽맥문동 6, 인삼 8, 관동화 6 및 꿀 4. 어린이 변비 치료용 중의약의 제조 방법 및 투여 방법은 상기와 동일하다.Dandelion, Cheonwooseul, Hamsohwa, Soyeopmaekmundong, Ginseng, Guandonghwa and honey were mixed according to the following ratio for the preparation of Chinese medicine for the treatment of constipation in children: Dandelion 25, Cheonwooseul 15, Hamsohwa 15, Lobemaekmundong 6, Ginseng 8 , Guandonghua 6 and honey 4. The manufacturing method and administration method of Chinese medicine for the treatment of constipation in children are the same as above.
중의약의 연속 투여 3일 후 변비 증상은 크게 완화되었으며, 배설물의 굳은 정도는 크게 완화되었으며, 중의약의 연속 투여의 또 다른 2일 후, 변비는 완전하게 제거되었다.After 3 days of continuous administration of Chinese medicine, the symptoms of constipation were greatly alleviated, and the hardness of excreta was greatly alleviated, and after another 2 days of continuous administration of Chinese medicine, constipation was completely eliminated.
Claims (5)
중량부 기준으로 민들레(Dandlion) 20-30, 천우슬(Cyathula officinalis) 10-20, 함소화(Michelia Figo) 10-20, 소엽맥문동(Ophiopogon japonicus) 4-10, 인삼(Ginseng) 4-10, 관동화(Flos farfarae) 4-8 및 꿀(Honey) 3-6을 혼합하고, 85% 농도의 에틸 알콜을 첨가하고, 50-60℃에서 반복된 초음파 추출을 수행하며, 개개의 추출 용액 모두를 수집하여 추출 용액을 얻는 단계;
추출 용액을 진공 농축시키고, 건조시켜 고체 연고를 얻는 단계;
고체 연고를 분쇄시켜 350-400 메쉬의 입자 크기를 갖는 초미세 분말을 얻고, 캡슐 내용물을 얻는 단계;
캡슐 내용물을 캡슐 외피에 포장하여 어린이 변비 치료용 중의약의 완제품을 얻는 단계를 포함하는, 어린이 변비 치료용 중의약의 제조 방법.As a method for preparing a Chinese medicine for the treatment of constipation in children,
Based on parts by weight, Dandlion 20-30, Cyathula officinalis 10-20, Michelia Figo 10-20, Ophiopogon japonicus 4-10, Ginseng 4-10, Mix Flos farfarae 4-8 and Honey 3-6, add 85% concentration ethyl alcohol, conduct repeated ultrasonic extraction at 50-60 ° C, collect all individual extraction solutions to obtain an extraction solution;
vacuum concentration of the extraction solution and drying to obtain a solid ointment;
crushing the solid ointment to obtain an ultra-fine powder having a particle size of 350-400 mesh, and obtaining capsule contents;
A method for producing a Chinese medicine for treating constipation in children, comprising the step of packaging the contents of the capsule in a capsule shell to obtain a finished product of the Chinese medicine for treating constipation in children.
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