KR102468216B1 - Cosmetic Composition For Hair With Preventing Hair Color Separation And Dyeing Hair Containing Cassia Tora Seed Extract As Active Ingredient - Google Patents

Abstract

The present invention relates to a cosmetic composition for hair with a hair color separation prevention effect and a natural hair dyeing effect, by containing a Cassia tora seed extract as an active ingredient. More specifically, the present invention relates to a cosmetic composition for natural hair dye containing a Cassia tora seed extract. The cosmetic composition according to the present invention has a hair dyeing effect by allowing negative ionic natural components of a natural extract to adsorb to positive ions of hair cuticles through ionic bonding.

Description

Cosmetic composition for hair containing Cassia tora extract as an active ingredient and having hair color loss prevention and dyeing effects {Cosmetic Composition For Hair With Preventing Hair Color Separation And Dyeing Hair Containing Cassia Tora Seed Extract As Active Ingredient}

The present invention relates to a cosmetic composition for hair containing Cassia tora extract as an active ingredient, which prevents hair color loss and has a natural dyeing effect, and more particularly, to a cosmetic composition for hair containing Cassia tora extract.

Hair dyes are classified into temporary, semi-permanent, and permanent hair dyes according to the continuous state of the color. The most common permanent hair dyes are designed so that the hair dye penetrates the cuticle and deposits the pigment molecules in the cortex. Permanent hair dyes can be divided into oxidation, metal and vegetable hair dyes according to dyes, and the most frequently used hair dyes are oxidation hair dyes using oxidation dyes such as aromatic amino compounds.

Oxidation dyes are generally in the form of oxidation-type hair dyes in which a first agent, which is a dye, and a second agent, which is an oxidizing agent, are mixed and used. The cuticle layer is opened by the alkali agent of the first agent, and the melanin pigment in the hair is bleached by the oxidizing agent of the second agent, and the dye components, which are monomeric compounds with a small molecular weight, pass through the cuticle layer and enter the center of the hair, where a polymerization reaction occurs and the cuticle layer is closed. It becomes dyed.

Oxidative hair dyes have excellent hair dyeing power, but have the disadvantage of slow hair dyeing and discoloration due to sunlight, washing, etc., strong alkali agents that swell the hair to facilitate the penetration of dyes and dye by oxidative polymerization inside the hair, mono Since the alkali agent such as ethanolamine is used together, the gloss and luster of the hair are lost and the hair may be severely damaged, resulting in an unnatural color and causing skin irritation and skin trouble. In addition, a large amount of dye used to increase dyeing power reduces the stability of the hair dye and causes hair damage and strong skin irritation. In particular, it does not erase well when it comes to skin troubles caused by hair dye. In severe cases, redness of the skin, erythema of the skin, or erythema such as hives may occur all over the body, and it may cause eye pain, so there are more limitations in use for sensitive people.

Therefore, in order to improve the disadvantages and inconveniences of these hair dyes, the development of natural hair dye materials that contain a large amount of natural hair dye ingredients, have excellent effects such as scalp protection and hair protection, are harmless to the human body and are easy to use, and use containing the materials The development of this easy hair dye is essential. If the dyeing method of the present invention is used, the problems listed above can be solved, and after dyeing, water loss by shampoo is reduced, and nutrition is supplied to the hair roots and scalp, as well as dyeing becomes natural.

Regarding the dye, Korean Patent Registration No. 10-1108783 (2012.01.16.) discloses a hair dye containing a mixed extract of rhubarb, Haosu, and Cassia tora.

Korean Patent Registration No. 10-1458877 (October 31, 2014) discloses a one-part oxidative hair dye composition containing natural ingredients of gall nut, seaweed, and persimmon leaf mixed extract.

Korean Patent Registration No. 10-2353526 (January 17, 2022) discloses a hair dye shampoo composition containing mixed extracts of mulberry fruit, moth bark, moth leaf, and biotite as active ingredients.

In order to improve the disadvantages and inconveniences of existing oxidative hair dyes, the present invention contains a large amount of natural hair dye ingredients, has excellent effects such as scalp protection and hair protection, and develops natural hair dye materials that are harmless to the human body and easy to use, and contain the materials It is intended to provide a composition having a function of preventing hair dyeing and color loss with a composition such as a general shampoo or rinse. In particular, the cosmetic composition according to the present invention is intended to provide a cosmetic composition having a dyeing effect by ionically bonding and adsorbing anionic natural components of natural extracts to cations of hair cuticles.

The above object is achieved by a cosmetic composition for hair containing Cassia tora extract as an active ingredient and having a hair color loss prevention and dyeing effect.

Preferably, the Cassia tora extract may be included in 0.01 to 30.0% by weight based on the total weight of the cosmetic composition.

Also preferably, the Cassia tora extract may be extracted at 45° C. with an aqueous ethanol solution having a concentration of 75.0% (v/v).

Also preferably, the cosmetic composition for hair may have a pH of 4.5 to 7.5.

Also preferably, the cosmetic composition for hair may have a formulation selected from the group consisting of shampoo, rinse and hair tonic.

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1 is a response surface analysis result according to the extraction conditions of the present invention.
Figure 2 is a photograph of hair dyed according to Preparation Examples 1 to 4 and Comparative Preparation Example 1 of the present invention.
3 is a photomicrograph of hair dyed according to Experimental Example 2 of the present invention.
4 is a photograph of hair dyed according to pH according to Experimental Example 4 of the present invention.
5 is a photograph showing the effect of preventing color loss of hair according to Experimental Example 5 of the present invention.

All technical terms used in the present invention, unless otherwise defined, have the following definitions and correspond to the meanings commonly understood by those of ordinary skill in the art related to the present invention. In addition, although preferred methods or samples are described in this specification, those similar or equivalent thereto are also included in the scope of the present invention.

The term "about" means a reference amount, level, value, number, frequency, percentage, dimension, size, amount, weight or length of 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, means an amount, level, value, number, frequency, percentage, dimension, size, quantity, weight or length that varies by 4, 3, 2 or 1%.

Throughout this specification, unless the context requires otherwise, the terms "comprise" and "comprising" include a given step or component, or group of steps or components, but any other step or component, or It is to be understood that steps or groups of components are not excluded.

The present invention relates to a cosmetic composition for hair containing Cassia tora extract as an active ingredient and having a hair color loss prevention and dyeing effect.

Cassia Tora Seed is 1 to 1.5 m tall, has pinnate leaves and 2 to 4 pairs of obovate leaves, and yellow flowers bloom from the axils of the leaves in July to August. After the leaves fall, a bow-shaped pod about 10 cm long opens. There is a row of shiny seeds in the pod, which is also called gyeolmyeongja and is drunk as tea or used for medicinal purposes. Seeds are columnar with a length of 3-6mm and a diameter of 2-3.5mm, with hairs, and light yellowish brown vertical lines and bands on both sides. Seeds have curved, dark-colored cotyledons. The country of origin is the United States, and it is cultivated in various parts of Korea.

The name Gyeolmyeong is derived from the meaning of brightening the eyes. It contains emodin, obtusifolin, and obtusin as active ingredients. As a result of animal experiments, the effect of lowering blood pressure was recognized, and in experiments using toads, it was found that there was an effect of constricting blood vessels and inhibiting the growth of Staphylococcus aureus, Escherichia coli, and influenza. The medicinal properties are cool, the taste is sweet and bitter, and it is effective in treating hepatitis, used for ascites due to cirrhosis of the liver, and is also effective in eye disease caused by lesions of the liver. Therefore, it is used for symptoms of bloodshot eyes or sore eyes that cannot see sunlight or tears. It is also used for acute conjunctivitis and corneal opacity. In addition, it is effective for diuresis and constipation, so it is known as a treatment for habitual constipation and high blood pressure.

The present invention provides a natural hair dye cosmetic composition comprising a Cassia tora extract having the above characteristics.

The Cassia tora extract is selected from the group consisting of water, alcohol having 1 to 4 carbon atoms, propylene glycol, butylene glycol, glycerin, acetone, ethyl acetate, chloroform, butyl acetate, diethyl ether, dichloromethane, hexane, and mixtures thereof Using an extraction solvent that is, it can be extracted from Cassia tora through any one extraction method selected from solvent extraction, supercritical extraction and ultrasonic extraction. Preferably, extraction is preferably performed using alcohol having 1 to 4 carbon atoms, alcohol having 1 to 4 carbon atoms or water, and most preferably, extraction can be performed at 45° C. using ethanol having a concentration of 75.0% (v/v). have.

In the cosmetic composition of the present invention, the Cassia tora extract is preferably contained in an amount of 0.1 to 80% by weight, preferably 1 to 30% by weight, based on the total weight of the cosmetic composition.

On the other hand, the composition for hair of the present invention may be prepared in any formulation commonly prepared in the art, and may be formulated into, for example, shampoo, rinse, hair tonic, and the like. However, it is not necessarily limited thereto.

Hereinafter, the contents of the present invention will be described in more detail in the following examples. However, the scope of the present invention is not limited only to the following examples, and includes modifications of equivalent technical ideas.

Experimental Example 1: Confirmation of Optimal Extraction Conditions for Cassia tora Extract

The main pigment components of Cassia tora are anthraquinone-based Emodin, carotenoid-based carotin, and flavonoid-based Kaempherol. Among them, Box-Behnken design and response surface analysis, a 3-level-3-factor experimental design, were used to model and optimize the process of extracting the maximum content of emodine from Cassia tora. Factors considered as important independent variables (Xn) in the extraction process, that is, ethanol concentration (ethanol concentration (%): X1), extraction temperature (temperature: X2), and the ratio of raw material to extraction solvent (ratio: X3) are factor variables. Therefore, it was coded in three stages (-1, 0, 1), and according to the Box-behnken design, an extraction experiment was conducted by setting it to 15 sections as shown in Table 1 below. In addition, regression analysis was performed by measuring the dependent variable affected by the independent variable as the content of emodine (Y1).

In the response surface analysis, the second-order regression equation for the dependent variable of the independent variable was as follows.

[Equation 1]

Y = b0 + b1X1 + b2X2 + b3X3 + b11X12+ b21X2X1 + b22X22+ b31X3X1 + b32X3X2 + b33X32

Here, Y is the dependent variable, X1, X2, and X3 are the independent variables, b0 is the intercept, and bn is the regression coefficient. Monitoring of extraction characteristics and prediction of optimal condition range were analyzed using response surfaces of each dependent variable.

Table 1 shows the extraction conditions of 15 sections designed by the Box-behnken design with the solvent conditions, extraction temperature, and the ratio of the raw material and the extraction solvent as independent variables to set the optimal extraction conditions for Emodin from the defect. . In addition, the emodine content obtained from each extract, that is, the results of the dependent variable are shown in Table 2. Response surface regression analysis was performed using these experimental results, and regression equations for dependent variables were obtained. In addition, the optimal extraction conditions for the dependent variable and the corresponding emodine content were predicted and shown in Table 3. In addition, in order to confirm the effect of the extraction conditions, the concentration of purified water, the extraction temperature, and the ratio of raw material and extraction solvent on the emodine content, a response surface curve is shown in FIG. 1.

The Emodin content for each extraction condition according to the Box-behnken design was as shown in Table 2, and the response surface regression equation for the results is shown in Equation 2 below.

[Equation 2]

Emodin= -109.170 + 2.4600X ₁ -2.72917X ₂ + 5.34333 X ₃ -0.02577 X ₁ ² -0.00729 X ₂ ² -0.03366 X ₃ ² + 0.07750 X ₁ X ₂ - 0.00533 X ₁ X _{3 -4.50787X 2} X

The regression equation for emodine content showed a high correlation with R2 of 0.973, and significance was recognized within 5% (Table 4).

Looking at the response surface graph shown in FIG. 1, the extraction solvent (ethanol concentration) among the extraction conditions had the greatest effect on the emodine content, and the higher the ethanol concentration, that is, the lower the purified water content, the higher the emodine content. showed a trend.

The maximum value of emodine predicted according to the response surface analysis was predicted to be 143.993 ppm, and the extraction conditions at this time were determined as ethanol concentration of 75.00% (v / v), extraction temperature of 45 ° C, and extraction time of 7.00 h for the sample. . That is, it was found that the highest yield of emodin could be obtained when extraction was performed at 45° C. for 7 hours in a solvent close to 100% (v/v) ethanol.

As a result of the above, it was confirmed that the extraction process with the maximum emodin content from Cassia tora was affected by the extraction conditions, that is, the ethanol concentration, extraction temperature, and extraction time ratio, and was particularly affected by the concentration of ethanol, the extraction solvent. It became. In addition, a regression equation with significance explaining the emodine content according to the extraction conditions was established, and the optimal extraction conditions for emodine extraction could be determined.

Examples 1-4: Preparation of Cassia tora Extract (Natural Hair Hybrid)

200 g of Cassia tora was pulverized to prepare a pulverized product. After separating the pulverized product into four pieces, 2000 g of ethanol at concentrations of 30% (v/v), 50% (v/v), 75% (v/v), and 100% (v/v) was added, respectively. Then, in an extractor equipped with a cooling condenser, extraction was performed by heating at 45° C. for 7 hours. After filtering each of the above extracts with a 400 mesh filter cloth, it was filtered again with Whatman No. 2 filter paper. After that, it was concentrated under reduced pressure at a temperature of 40 ° C using a distillation apparatus equipped with a cooling condenser, and the residue was repeated once more under the same conditions to prepare Cassia tora extracts of Examples 1 to 4, respectively (Table 5).

division Example 1 Example 2 Example 3 Example 4 ethanol concentration 75% (v/v) 100% (v/v) 50% (v/v) 30% (v/v)

Experimental Example 1: Analysis of Emodin Content of Cassia tora Extract (Natural Hair Hybrid)

The content of emodin in the Cassia tora extracts prepared in Examples 1 to 4 was analyzed using HPLC (Waters 2695) for the extracts that had passed through a 0.45 μm filter. At this time, as the analysis conditions, Optimapak C18 250 - 4.6 μm was used as the column, 25% ACN and 75% DW as the mobile phase, 1.0 ml/min as the flow rate, and UV (254 nm) as the detector. Quantification was performed by creating a calibration curve using an external standard method. That is, after dissolving the standard substance Emodin in methanol to 1000 ppm, diluting this solution to prepare standard solutions for each 500, 250, and 125 ppm, analyzing by HPLC, and then preparing a calibration curve for quantification. As a result of the measurement, the emodin content of Example 1 having an ethanol concentration of 75 (v/v)% was the highest.

ingredient Example 1 Example 2 Example 3 Example 4 Emodine content (ppm) 148 127 124 98

Experimental Example 2: Analysis of staining effect

Preparation Examples 1 to 4 were prepared by diluting the Cassia tora extract obtained in Examples 1 to 4 with purified water to 1% by weight. In addition, Comparative Preparation Example 1 containing 1,000 ppm of Emodin (Sigma Aldrich, cas no. 518-82-1) was prepared.

Ingredients (% by weight) Preparation Example 1 Preparation Example 2 Preparation Example 3 Production Example 4 Comparative Preparation Example 1 Example 1 1.0 - - - - Example 2 - 1.0 - - - Example 3 - - 1.0 - - Example 4 - - - 1.0 - Emodin - - - - 1000 ppm Purified water balance balance balance balance balance total 100.0 100.0 100.0 100.0 100.0

After washing white hair (Brand TV Hair Mart, OM2LSW) with water, Preparation Examples 1 to 4 and Comparative Preparation Example 1 were applied using shampoo for about 2 minutes, then rinsed with water and dried once a day for 7 days. After repetition, the effect of dyeing gray hair was confirmed. The results are shown in FIG. 2 .

As a result, it was confirmed that the difference in dyeing effect was shown in the order of Preparation Example 1> Preparation Example 3> Preparation Example 2 = Preparation Example 4> Comparative Preparation Example 1 (Emodin 1000ppm). Although the difference was not large, the best dyeing effect was exhibited when the Cassia tora extract extracted under the condition that the most emodin content was extracted (Preparation Example 1) was included.

3 is a photomicrograph of hair after dyeing for 7 days with white horse before dyeing and Preparation Example 1. Referring to FIG. 3, after using Preparation Example 1 for 7 days, it can be confirmed that gray hair is dyed.

Experimental Example 3: Dyeing effect of Cassia tora extract (Natural Hair Hybrid) according to pH change

In order to confirm the dyeing effect according to the pH of Cassia tora extract, the dyeing effect was confirmed by adjusting the pH to be acidic, neutral, or basic. Each pH adjustment used citric acid and sodium chloride.

A composition containing 1% by weight of the Cassia tora extract of Example 1 was prepared by pH, applied to bleached hair for 2 to 3 minutes, rinsed with water, and then dried once a day for 7 days. After repeated use, the dyeing effect Confirmed. The results are shown in FIG. 4 . Referring to Figure 4, it was confirmed that the dyeing effect was the best when the pH was 7.

Ingredients (% by weight) Preparation Example 5 Preparation Example 6 Preparation Example 7 Cassia tora Extract
(Example 1) 1.0 1.0 1.0 Citric Acid/Sodium Chloride Appropriate amount Appropriate amount - Purified water balance balance balance total 100.0 100.0 100.0 pH reading 4.0 7.0 10.0

Formulation Example 1: Preparation of Shampoo Composition Containing Cassia tora Extract (Natural Hair Hybrid)

Formulation Example 1 containing 1% by weight of Cassia tora extract obtained in Example 1 and prepared as a shampoo formulation is shown in Table 9 below.

Ingredients (% by weight) Formulation example 1 Cassia tora Extract
(Example 1) 1.0 Disodium EDT 0.03 Polyquaternium-10 0.1 Ammonium Lauryl Sulfate 40.5 Ammonium Laureth Sulfate 15.5 Cocamidopropyl Betaine 6.0 propylene glycol 2.0 sodium xylene sulfonate 2.0 Glycol Distearate 3.0 Cocamide DEA 1.0 Lauramide DEA 1.0 salicylic acid 0.13 dimethicone 3.0 antiseptic Appropriate amount incense Appropriate amount Purified water balance total 100.0

Experimental Example 4: Effect of preventing color loss of hair

For hair dyeing, commercially available white hair was purchased through TV Hair Mart (catalog number, OM2LSW). Gray hair cover dark brown 3.0 (Ryo Jayangyunmo) was purchased on the market, and after mixing the first hair dye and the second oxidizing agent, which are oxidation-type hair dyes, it was applied to white hair for 15 minutes, rinsed with water, and dried to dye gray hair.

Thereafter, after washing with the general shampoo and the shampoo of Formulation Example 1, the process of rinsing with running water until clear water came out was repeated twice a day for 30 days, and then the initial color was compared with the color difference meter to confirm hair color loss. . The color loss results are shown in FIG. 5 . Referring to Figure 5, it was confirmed that there is an effect of preventing color loss in the shampoo containing 1.0% by weight of Cassia tora. General shampoo increased color loss, but in the case of shampoo containing Cassia tora extract, it was confirmed that the effect of preventing color loss due to hair coating was excellent.

Formulation Example 2: Preparation of rinse composition containing Cassia tora extract (Natural Hair Hybrid)

Formulation Example 2 containing 1.0% by weight of Cassia tora extract obtained in Example 1 and prepared as a rinse formulation is shown in Table 10 below.

Ingredients (% by weight) Formulation Example 2 Cassia tora Extract
(Example 1) 1.0 Disodium EDT 0.02 Hydroxyethyl Cellulose 0.2 panthenol 0.05 propylene glycol 1.5 glycerin 2.0 cetyl alcohol 3.5 Stearyl Alcohol 1.5 Glyceryl Stearate SE 0.5 dimethicone 1.5 antiseptic Appropriate amount incense Appropriate amount Purified water balance total 100.0

Formulation Example 3: Preparation of hair tonic composition containing Cassia tora extract (Natural Hair Hybrid)

Formulation Example 3 containing 1.0% by weight of Cassia tora extract obtained in Example 1 and prepared as a hair tonic formulation is shown in Table 11 below.

Ingredients (% by weight) Formulation Example 3 Cassia tora Extract
(Example 1) 1.0 Disodium EDT 0.02 panthenol 0.5 Butylene Glycol 10.0 ethanol 18.0 menthol 0.03 Polysorbate 80 1.0 imidazolidinyl urea 0.2 biotin 0.1 incense Appropriate amount Purified water balance total 100.0

Experimental Example 5: Investigation of Satisfaction with Dyeing Effect and Color Loss Prevention Effect

30 subjects with gray hair were divided into 2 groups, and the shampoo (experimental group) and general shampoo (control group) of Formulation Example 1 were used for 30 days, and the satisfaction with the results of the dyeing effect and the color loss prevention effect was investigated. The results are shown in Table 12 below. Referring to Table 12, a number of users in the group using the shampoo of Formulation Example 1 gave a “very good” evaluation in the dyeing effect and color loss prevention effect.

division control group experimental group dye effect very good 0 12 good 4 16 no change 26 2 Color fading prevention effect very good 2 19 good 10 10 no change 18 One

Claims (5)

A cosmetic composition for hair containing Cassia tora extract as an active ingredient, wherein the cosmetic composition for hair has a pH of 4.5 to 7.5 and has a formulation selected from the group consisting of shampoo, rinse and hair tonic, characterized in that it has a hair color loss prevention and dyeing effect A cosmetic composition for hair having a. According to claim 1,
The Cassia tora extract is a cosmetic composition for hair, characterized in that contained in 0.01 to 30.0% by weight relative to the total weight of the cosmetic composition. According to claim 1,
The Cassia tora extract is a cosmetic composition for hair, characterized in that extracted at 45 ℃ with an ethanol aqueous solution of 75.0% (v / v) concentration. delete delete

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