KR102398465B1 - 종양의 심층 서열분석 프로파일링 - Google Patents

종양의 심층 서열분석 프로파일링 Download PDF

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KR102398465B1
KR102398465B1 KR1020187023352A KR20187023352A KR102398465B1 KR 102398465 B1 KR102398465 B1 KR 102398465B1 KR 1020187023352 A KR1020187023352 A KR 1020187023352A KR 20187023352 A KR20187023352 A KR 20187023352A KR 102398465 B1 KR102398465 B1 KR 102398465B1
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sample
sequencing
genomic material
capture
amplification
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KR20180098412A (ko
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넬슨 알렉산더
다니엘 버지스
스테이시 스타니슬라프
헤이디 로젠바움
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벤타나 메디컬 시스템즈, 인코포레이티드
에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/146—Concentration of target or template
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Prostheses (AREA)
KR1020187023352A 2016-01-15 2016-11-07 종양의 심층 서열분석 프로파일링 Active KR102398465B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662279126P 2016-01-15 2016-01-15
US62/279,126 2016-01-15
US201662415952P 2016-11-01 2016-11-01
US62/415,952 2016-11-01
PCT/US2016/060835 WO2017123316A1 (en) 2016-01-15 2016-11-07 Deep sequencing profiling of tumors

Publications (2)

Publication Number Publication Date
KR20180098412A KR20180098412A (ko) 2018-09-03
KR102398465B1 true KR102398465B1 (ko) 2022-05-13

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KR1020187023352A Active KR102398465B1 (ko) 2016-01-15 2016-11-07 종양의 심층 서열분석 프로파일링

Country Status (12)

Country Link
US (2) US11649492B2 (https=)
EP (1) EP3402896B1 (https=)
JP (2) JP7232643B2 (https=)
KR (1) KR102398465B1 (https=)
CN (1) CN108463559A (https=)
AU (1) AU2016386032B2 (https=)
CA (1) CA3011342C (https=)
IL (1) IL260304B2 (https=)
SA (1) SA518392005B1 (https=)
SG (1) SG11201805600VA (https=)
WO (1) WO2017123316A1 (https=)
ZA (1) ZA201804322B (https=)

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ES2986436T3 (es) 2011-04-15 2024-11-11 Univ Johns Hopkins Sistema de secuenciación segura
ES2886507T5 (es) 2012-10-29 2024-11-15 Univ Johns Hopkins Prueba de Papanicolaou para cánceres de ovario y de endometrio
US11286531B2 (en) 2015-08-11 2022-03-29 The Johns Hopkins University Assaying ovarian cyst fluid
SG11201805600VA (en) * 2016-01-15 2018-07-30 Ventana Med Syst Inc Deep sequencing profiling of tumors
CN111868260B (zh) 2017-08-07 2025-02-21 约翰斯霍普金斯大学 用于评估和治疗癌症的方法和材料
US20200004928A1 (en) 2018-06-29 2020-01-02 Roche Sequencing Solutions, Inc. Computing device with improved user interface for interpreting and visualizing data
CN109234356B (zh) * 2018-09-18 2021-10-08 南京迪康金诺生物技术有限公司 一种构建杂交捕获测序文库的方法及应用
CN113383089A (zh) * 2018-11-29 2021-09-10 文塔纳医疗系统公司 经由代表性DNA测序进行个性化ctDNA疾病监测
WO2020136133A1 (en) 2018-12-23 2020-07-02 F. Hoffmann-La Roche Ag Tumor classification based on predicted tumor mutational burden
WO2020249704A1 (en) 2019-06-13 2020-12-17 F. Hoffmann-La Roche Ag Systems and methods with improved user interface for interpreting and visualizing longitudinal data
EP4103748A4 (en) 2020-02-14 2024-03-13 The Johns Hopkins University METHOD AND MATERIALS FOR ASSESSING NUCLEIC ACIDS
JPWO2022244856A1 (https=) 2021-05-20 2022-11-24

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WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
US20150126379A1 (en) 2013-10-28 2015-05-07 The Translational Genomics Research Institute Long insert-based whole genome sequencing
WO2017123316A1 (en) 2016-01-15 2017-07-20 Ventana Medical Systems, Inc. Deep sequencing profiling of tumors

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US5176995A (en) 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US20080119367A1 (en) * 2004-12-17 2008-05-22 Mayo Foundation For Medical Education And Research Prognosis of Renal Cell Carcinoma
WO2009061840A1 (en) * 2007-11-05 2009-05-14 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
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WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
US20150126379A1 (en) 2013-10-28 2015-05-07 The Translational Genomics Research Institute Long insert-based whole genome sequencing
WO2017123316A1 (en) 2016-01-15 2017-07-20 Ventana Medical Systems, Inc. Deep sequencing profiling of tumors

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Also Published As

Publication number Publication date
IL260304A (en) 2018-08-30
US11649492B2 (en) 2023-05-16
EP3402896B1 (en) 2021-03-31
JP2019503182A (ja) 2019-02-07
EP3402896A1 (en) 2018-11-21
US20230250476A1 (en) 2023-08-10
AU2016386032B2 (en) 2021-08-12
WO2017123316A1 (en) 2017-07-20
KR20180098412A (ko) 2018-09-03
CA3011342A1 (en) 2017-07-20
AU2016386032A1 (en) 2018-07-12
BR112018014349A2 (pt) 2019-02-12
JP7232643B2 (ja) 2023-03-03
ZA201804322B (en) 2022-10-26
SA518392005B1 (ar) 2022-02-08
CA3011342C (en) 2023-03-14
US20180320229A1 (en) 2018-11-08
IL260304B2 (en) 2025-04-01
CN108463559A (zh) 2018-08-28
SG11201805600VA (en) 2018-07-30
JP7379418B2 (ja) 2023-11-14
JP2021176302A (ja) 2021-11-11
IL260304B1 (en) 2024-12-01

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