KR102382930B1 - 항균 내성을 회피하는 항-설사 제형물 - Google Patents

항균 내성을 회피하는 항-설사 제형물 Download PDF

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KR102382930B1
KR102382930B1 KR1020177008106A KR20177008106A KR102382930B1 KR 102382930 B1 KR102382930 B1 KR 102382930B1 KR 1020177008106 A KR1020177008106 A KR 1020177008106A KR 20177008106 A KR20177008106 A KR 20177008106A KR 102382930 B1 KR102382930 B1 KR 102382930B1
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South Korea
Prior art keywords
formulation
piglets
diarrhea
bromelain
weaning
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Expired - Fee Related
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KR1020177008106A
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English (en)
Korean (ko)
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KR20170082149A (ko
Inventor
트래시 엘 미노트
죤 왈시
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아나타라 라이프사이언시즈 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22032—Stem bromelain (3.4.22.32)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22033—Fruit bromelain (3.4.22.33), i.e. juice bromelain
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020177008106A 2014-08-25 2015-08-24 항균 내성을 회피하는 항-설사 제형물 Expired - Fee Related KR102382930B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462041175P 2014-08-25 2014-08-25
US62/041,175 2014-08-25
PCT/US2015/046509 WO2016032944A1 (en) 2014-08-25 2015-08-24 Anti-diarrhea formulation which avoids antimicrobial resistance

Publications (2)

Publication Number Publication Date
KR20170082149A KR20170082149A (ko) 2017-07-13
KR102382930B1 true KR102382930B1 (ko) 2022-04-04

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KR1020177008106A Expired - Fee Related KR102382930B1 (ko) 2014-08-25 2015-08-24 항균 내성을 회피하는 항-설사 제형물

Country Status (11)

Country Link
US (1) US20170239334A1 (https=)
EP (1) EP3193629B1 (https=)
JP (1) JP6920199B2 (https=)
KR (1) KR102382930B1 (https=)
CN (2) CN114711336A (https=)
AU (2) AU2015306904A1 (https=)
CA (1) CA2959361A1 (https=)
DK (1) DK3193629T3 (https=)
ES (1) ES2938347T3 (https=)
PH (1) PH12017500338B1 (https=)
WO (1) WO2016032944A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4041285B1 (en) * 2019-10-11 2024-09-18 Anatara Lifesciences Limited Gastrointestinal health composition
MX2022011112A (es) * 2020-03-12 2022-10-07 Abbott Lab Metodos para tratar la diarrea o afecciones inflamatorias del intestino.
CN112618579B (zh) * 2020-12-24 2022-02-15 南京农业大学 一种防治仔猪腹泻复合益生菌制剂和制备方法及应用
EP4294426A1 (en) * 2021-02-16 2023-12-27 DSM IP Assets B.V. Methods for reducing pathogenic e coli by selective feed additive intervention comprising enzymes such as muramidase
PL246387B1 (pl) * 2022-08-16 2025-01-20 Nutropharma Spolka Z Ograniczona Odpowiedzialnoscia Kompozycja doustna i jej zastosowanie
KR102592953B1 (ko) * 2023-01-30 2023-10-20 박예성 휴지기 없이 급여 가능한 반려동물용 영양제 제조공법
CN116889261B (zh) * 2023-07-22 2025-07-04 广东加大实业有限公司 一种防治腹泻乳猪饲料及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1548154A (zh) * 2003-05-22 2004-11-24 维奥（四川）生物技术有限公司 用于治疗哺乳动物腹泻的菠萝蛋白酶微胶囊化药物组合物
US20060052438A1 (en) 2004-04-30 2006-03-09 Chi-Tang Ho Bioactive compounds and methods of uses thereof

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
JP2798248B2 (ja) * 1986-08-28 1998-09-17 コーテックス リミテッド 生物学的活性物質の動物の腸管部位へのデリバリーに有効なマイクロ顆粒状製剤
HUT67007A (en) * 1991-07-24 1995-01-30 Enzacor Pty Ltd Preparations containing biologically activ agent wich are absorbed in the superior intestinal tract of animals
US6054261A (en) * 1998-05-20 2000-04-25 Q-Pharma, Inc. Coenzyme Q10 compositions for organ protection during perfusion
US6080403A (en) * 1998-06-18 2000-06-27 Star-Kist Foods, Inc. Protease containing hairball remedy and use thereof
AU2003205738A1 (en) * 2002-02-14 2003-09-04 Dsm Ip Assets B.V. Water-dispersible coenzyme q10 dry powders
WO2008049437A1 (en) * 2006-10-26 2008-05-02 Biofiber-Damino A/S Composition comprising lignin and antidi arrheal component
WO2009009879A1 (en) * 2007-07-13 2009-01-22 Aquience Inc. Beverage composition for non-human animals
AT506095A1 (de) * 2007-12-03 2009-06-15 Volopharm Gmbh Verwendung von proteasen
CN102300989B (zh) * 2009-01-06 2015-12-09 柯尔朗恩有限责任公司 用于治疗或预防金黄色葡萄球菌感染以及用于根除或减少表面上金黄色葡萄球菌的组合物和方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1548154A (zh) * 2003-05-22 2004-11-24 维奥（四川）生物技术有限公司 用于治疗哺乳动物腹泻的菠萝蛋白酶微胶囊化药物组合物
US20060052438A1 (en) 2004-04-30 2006-03-09 Chi-Tang Ho Bioactive compounds and methods of uses thereof

Also Published As

Publication number Publication date
CA2959361A1 (en) 2016-03-03
EP3193629A4 (en) 2018-07-11
JP2017532369A (ja) 2017-11-02
DK3193629T3 (da) 2023-03-13
KR20170082149A (ko) 2017-07-13
PH12017500338B1 (en) 2023-01-13
AU2019204496A1 (en) 2019-07-18
US20170239334A1 (en) 2017-08-24
AU2015306904A1 (en) 2017-04-06
JP6920199B2 (ja) 2021-08-18
PH12017500338A1 (en) 2017-07-17
AU2019204496B2 (en) 2020-12-24
CN114711336A (zh) 2022-07-08
WO2016032944A4 (en) 2016-04-28
CN106998749A (zh) 2017-08-01
ES2938347T3 (es) 2023-04-10
WO2016032944A1 (en) 2016-03-03
EP3193629B1 (en) 2023-01-25
EP3193629A1 (en) 2017-07-26

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