KR102309611B1 - Methode for health functional food including ingredients in ginseng and health functional food produced by the same and oral disintegrating film produced by the same - Google Patents

Abstract

The present invention provides a method for manufacturing fine powder including an active ingredient in ginseng, a method for manufacturing a health functional food, and an oral disintegrating film manufactured by a method for manufacturing a health functional food. The method for manufacturing fine powder including an active ingredient in ginseng comprises: a step of a two-year-old ginseng seedling; a step of cultivating the two-year-old ginseng seedling by a spray-type hydroponic cultivating method; a step of separating cultivated ginseng from a first part consisting of leaves and stems and a second part consisting of a head and a root; a step of separately drying the first part and the second part of the ginseng with microwaves; and a step of finely powdering the first part and the second part of the dried ginseng into 1000-1100 mesh. The cultivating step includes: a first step of freezing and storing the two-year-old ginseng seedling in a temperature range of -4 to -1℃; a second step of aging the two-year-old ginseng seedling in a temperature range of 4 to 6℃ after the first step; a third step of washing the ginseng seedling after the two step; a fourth step of planting the ginseng seedling on a planting plate after the three step; a fifth step of turning on an LED when a sprout of the ginseng seedling is germinated after the fourth step and growing the same; and a step of harvesting ginseng grown after the fifth step. The present invention can minimize remaining of harmful components.

Description

A method for manufacturing a health functional food containing ginseng active ingredient, and a health functional food and an oral disintegrating film manufactured thereby }

The present invention relates to a method for manufacturing a health functional food containing ginseng active ingredient, and to a health functional food and an orally disintegrating film produced thereby.

Recently, as the economy develops and the standard of living improves, the demand for various health functional foods that can improve health functions in addition to basic food, clothing and shelter has increased. It is released and sold.

Among them, ginseng has a large amount of saponin useful for the human body, and many modern people consume ginseng itself or various health functional foods using ginseng. am. Therefore, research is continuously being conducted to process ginseng to make it easier to consume or to maximize the effect even when a small amount of health functional food is consumed by maximizing the active ingredient. In addition, in the case of ginseng, since ginseng itself is an expensive product due to its efficacy, technology to extract the active ingredients of ginseng as much as possible is continuously being developed.

On the other hand, in the conventional case, in the process of extracting the active ingredient from ginseng, most of the active ingredients are dissolved in water or extracted using drugs or solvents. There was a problem.

As such, the need for health functional foods containing useful ingredients for the human body is increasing according to the increasingly poor environment and modern people's interest in health. There is a need for research on health functional foods containing ginseng active ingredients that make it possible.

Korean Patent Publication No. 10-2005-0120444 (published on Dec. 22, 2005)

Accordingly, the problem to be solved by the present invention is to maximize the utilization of the ginseng active ingredient, and to provide a method for manufacturing a fine powder containing the ginseng active ingredient that can be consumed conveniently and without burden, and a method for manufacturing a health functional food using the same want to

In addition, by containing various useful ingredients, it is easy to consume while enjoying effects such as improvement of blood circulation in the human body, improvement of brain health, antioxidant effect, immunity function and various functions of the human body, and harmful ingredients such as heavy metals An object of the present invention is to provide a method for manufacturing a fine powder containing an active ginseng ingredient that can minimize the residual of ginseng and a method for manufacturing a health functional food using the same.

In addition, an object of the present invention is to provide an orally disintegrating film containing ginseng active ingredient that is easy to ingest and easy to store while being prepared by the above-described manufacturing method.

The subject of this invention is not limited to the above-mentioned content. The subject of the present invention will be understood from the overall content of the present specification, and those of ordinary skill in the art to which the present invention pertains will have no difficulty in understanding the additional subject of the present invention.

The method for producing fine powder comprising ginseng active ingredient according to an embodiment of the present invention for solving the above problems includes the steps of preparing two-year-old seedlings, cultivating the two-year-old seedlings by a spray-watering hydroponics method, cultivation separating the first part composed of leaves and stems and the second part composed of brain heads and roots of the ginseng, drying the first part and the second part of the ginseng separately with microwaves, and the dried Comprising the step of finely pulverizing the first part and the second part of ginseng to 1000mesh to 1100mesh, the cultivating step is to freeze and store the two-year-old seedlings in a temperature range of -4°C to -1°C. The first step, the second step of aging in a temperature range of 4°C to 6°C after the first step, the third step of washing the seedlings after the second step, and planting the seedlings on the planting plate after the third step The fourth step, a fifth step of growing by lighting an LED when the sprouts germinate on the seedlings after the fourth step, and harvesting the grown ginseng after the fifth step.

In addition, the first step may be performed for 2 to 8 months, and the second step may be performed for 3 to 7 days.

In addition, the third step is a first washing step of high-pressure washing using water, a second washing step of immersing in water in a temperature range of 20°C to 30°C for 15 minutes to 35 minutes, and water of the second washing step It may be characterized in that it comprises a third washing step of immersion in water in the temperature range of 20 ° C to 30 ° C for 1 hour to 2 hours by exchange.

In addition, it may further include spraying the seedlings in the fifth step after storing the water used in the third washing step at a temperature range of 4 ℃ to 6 ℃.

In addition, in the fourth step, after fixing the planting plate upside down, the brain heads of the seedlings are planted in the grooves formed on the planting plate so that the seedlings are planted, and water is sprayed on the whole seedlings after planting, characterized in that can do.

In addition, the fifth step is the 5-1 step, the 5-1 step of continuously supplying moisture to the seedlings in the dark state and stopping the supply of moisture when the sprouts of the seedlings germinate to a size of 8 cm to 12 cm After stopping the supply of moisture to the sprout part of the seedlings, step 5-2 of turning on the LED for 19 hours to 21 hours a day in a state of supplying moisture in a temperature range of 12 ° C to 15 ° C only to the root part of the seed ginseng , and may be characterized in that it comprises a step 5-3 of repeating the step 5-2 for 23 to 27 days.

In addition, the drying with the microwave includes a first drying step of drying the first portion of the cultivated ginseng, and a second drying step of drying the second portion, the first drying step is the For a total weight of 4 kg of leaves and stems of ginseng, which is one part, it is dried in two parts at a current of 40A for a time of 70 to 90 minutes, and the second drying step is the brain head and root of the second part, ginseng. It can be characterized in that the drying is divided into two times for a time of 70 minutes to 90 minutes at a current of 40A for a total weight of 8kg.

On the other hand, the health functional food manufacturing method comprising ginseng active ingredient according to an embodiment of the present invention for solving the above problems is a step of preparing two-year-old seedlings, cultivating the two-year-old seedlings by a spray-watering hydroponics method. Step, separating the cultivated ginseng from the first part consisting of leaves and stems and the second part consisting of the brain head and the root, drying the first part and the second part of the ginseng separately with microwaves, The first part and the second part of dried ginseng are finely powdered to 1000 mesh to 1100 mesh to prepare a fine ginseng powder, and the fine ginseng powder, zinc oxide, tocopherol, vitamin B12, solvent and other additives are mixed However, the step of culturing, the first step of freezing the two-year-old seedlings at a temperature range of -4 ° C to -1 ° C, and aging at a temperature range of 4 ° C to 6 ° C after the first step After the second step, the third step of washing the seedlings after the second step, the fourth step of planting the seedlings on the planting plate after the third step, the LED is turned on when the seedlings germinate after the fourth step to the fifth step of growing and harvesting the ginseng grown after the fifth step.

In addition, the mixing step may be characterized in that it further comprises a film-forming component, and after the mixing step, the mixture is applied on a release film and dried to prepare an orally disintegrating film substrate.

In addition, in the mixing step, the fine ginseng powder in the range of 22 wt% to 27 wt%, zinc oxide in the range of 0.2 wt% to 0.6 wt%, tocopherol in the range of 0.7 wt% to 1.1 wt%, relative to the total weight of the mixed mixture, Vitamin B12 in the range of 0.1 wt% to 0.2 wt%, a solvent in the range of 55 wt% to 65 wt% and other additives may be included.

In addition, the fine ginseng powder in the range of 55% to 65% by weight, zinc oxide in the range of 0.5% to 1.5% by weight, 1.5% by weight to 2.5% by weight relative to the total weight of the dried solid content of the prepared orally disintegrating film base of tocopherol, vitamin B12 in the range of 0.2 wt% to 0.4 wt%, and other additives and film-forming components.

On the other hand, an orally disintegrating film according to an embodiment of the present invention for solving the above problems is manufactured by the method for manufacturing a health functional food, and the orally disintegrating film is formed on a release film, and the release film and inside Including an orally disintegrating film substrate dried by including the active ingredient of the mixture, the orally disintegrating film substrate is formed in a plurality of spaced apart from each other on the release film on a horizontal cross-section, between adjacent oral disintegrating film substrates is separated by a diagonal line.

In addition, the orally disintegrating film may be characterized in that the release film and the orally disintegrating film substrate are configured in a roll form.

In addition, the orally disintegrating film substrate has a horizontal cross-sectional shape of a single orally disintegrating film substrate while a plurality of orally disintegrating film substrates are spaced apart from each other on the release film, respectively, in the shape of a parallelogram, and a long diagonal of a parallelogram All of these may be characterized in that the orally disintegrating film substrate is disposed so as to face in parallel in the same direction.

According to the method for manufacturing fine powder and health functional food containing the ginseng active ingredient of the present invention, it is possible to maximize the utilization of the ginseng active ingredient, and the fine powder that can be consumed easily and without burden, and health functional food containing the same , an orally disintegrating film can be prepared.

In addition, by containing various useful ingredients, it is possible to enjoy effects such as improvement of blood circulation of the human body, improvement of brain health, antioxidant effect, immunity function and various functions of the human body, and the residual of harmful components such as heavy metals can be enjoyed. can be minimized

In addition, the orally disintegrating film prepared by the above-described manufacturing method can be easily ingested and easily stored.

1 is a flowchart schematically illustrating a method for producing a fine powder including ginseng active ingredient according to an embodiment of the present invention.
2 is a flowchart specifically showing the step of cultivating seedlings of ginseng as ginseng according to an embodiment of the present invention.
3 is a flowchart schematically illustrating a method for manufacturing a health functional food including ginseng active ingredient according to an embodiment of the present invention.
4 is a schematic plan view of an orally disintegrating film according to an embodiment of the present invention.

Advantages and features of the present invention and methods of achieving them will become apparent with reference to the embodiments described below in detail in conjunction with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but will be implemented in a variety of different forms, and only these embodiments allow the disclosure of the present invention to be complete, and common knowledge in the technical field to which the present invention belongs It is provided to fully inform the possessor of the scope of the invention, and the present invention is only defined by the scope of the claims. Like reference numerals refer to like elements throughout. Sizes and relative sizes of layers and regions in the drawings may be exaggerated for clarity of description.

Spatially relative terms "below", "beneath", "lower", "above", "upper", etc. refer to one element or component and another. It can be used to easily describe a correlation with an element or components. In addition, in the present specification, "one side" means a surface in one direction spatially, and "the other side" may mean a surface opposite to the "one surface" spatially, but these are also one element or components and can be used to easily describe the correlation with other devices or components.

Although the first, second, etc. are used to describe various elements, of course, these elements are not limited by these terms. These terms are only used to distinguish one component from another. Accordingly, it goes without saying that the first component mentioned below may be the second component within the spirit of the present invention.

Hereinafter, embodiments of the present invention will be described with reference to the drawings. However, the embodiment of the present invention may be modified in various other forms, and the scope of the present invention is not limited to the embodiments described below. Further, the embodiments of the present invention are provided in order to more completely explain the present invention to those of ordinary skill in the art.

1 is a flowchart schematically illustrating a method for producing a fine powder including ginseng active ingredient according to an embodiment of the present invention. In addition, FIG. 2 is a flowchart specifically showing the step of cultivating seedlings of ginseng into ginseng according to an embodiment of the present invention.

1 and 2, the method for producing a fine powder containing ginseng active ingredient includes the steps of preparing two-year-old seedlings (S10), cultivating the two-year-old seedlings by a spray-watering hydroponics method (S20), cultivation Separating the first part consisting of leaves and stems of the ginseng and the second part consisting of brain heads and roots (S30), drying the first part and the second part of the ginseng separately with microwaves ( S40) and a step (S50) of finely pulverizing the first part and the second part of the dried ginseng to 1000mesh to 1100mesh, wherein the cultivating step (S20), the two-year-old seedlings at -4 ℃ The first step (S201) of refrigerated storage at a temperature range of to -1°C, the second step (S202) of aging at a temperature range of 4°C to 6°C after the first step (S202), and washing the seedlings after the second step A third step (S203), a fourth step of planting the seedlings on a planting plate after the third step (S204), and a fifth step (S205) of growing by lighting an LED when the seedlings germinate after the fourth step (S205) ) and harvesting the ginseng grown after the fifth step (S206).

In the step (S10) of preparing two-year-old seedlings, for example, 200 to 300 roots of seedlings per one (750g) may be used. An average of about 2 g to 3 g of seedlings per root is used, for example, lotus, geumpung, and K1 seedlings can be used. For seedlings, seedlings with thick trunks and large brains can be used, and seedlings with yellowing or wounds can be filtered out and not used.

It is possible to completely remove the residual pesticide components and heavy metal components present in the seedlings by the step (S20) of cultivating two-year-old seedlings by a spray-watering hydroponics method. The hydroponics method is not a method of immersing seedlings in water when planting, but a method of floating in the air and spraying water to supply moisture, so that heavy metals and residual pesticides remaining in existing seedlings are completely removed during the rapid cultivation period and can not be detected. As a result, all parts such as leaves and stems that were difficult to use in the past can be used. In other words, it is possible to remove heavy metals and residual pesticides that were present in leaves and stems by spraying hydroponics. The spraying hydroponics method will be described later, but after planting the seedlings on the planting plate, it can be floated in the air to spray water differentially on the top and bottom of the seedlings. It will be explained through explanation.

The step of separating the cultivated ginseng from the first part consisting of leaves and stems and the second part consisting of the head and roots (S30) is to divide the first part and the second part, respectively, and to dry them under different conditions through microwaves. For this purpose, when ginseng is harvested from cultivated ginseng, the top of the brain head is partially cut, and the first part composed of leaves and stems and the second part composed of leaves and roots are separated and collected, washed and stored separately. . In the case of the present invention, as described above, in order to maximize the efficiency of ginseng, the first part divided into leaves and stems can also be used for health functional foods, which have conventionally been used only with the brain head and root of ginseng. The first part and the second part are separated for drying. In the case of ginseng, in terms of the saponin content, the root has a content of 14.3 to 15.8 mg/g, and the leaf contains 140.8 to 180 mg/g of saponin, which shows a 9 times higher saponin content in the leaf than in the root. Similarly, by separating the first part and the second part and using all of them, it is possible to utilize all of the high content of saponins in one ginseng.

In the microwave drying step (S40), the first part and the second part may be separately divided and dried. Specifically, the microwave drying step (S40) includes a first drying step of drying the first part of the cultivated ginseng, and a second drying step of drying the second part, and the first The drying step is divided into two parts for a time of 70 to 90 minutes at a current of 40A for a total weight of 4 kg of leaves and stems of ginseng, which is the first part, and the second drying step is the second part. It can be characterized in that it is divided into two parts and dried for a time of 70 to 90 minutes at a current of 40A for a total weight of 8 kg of the brain head and root of ginseng. It may be possible to form an optimal drying condition in the current and temperature range, and to be finely powdered to 1000mesh to 1100mesh.

The step of fine-powdering (S50) may be a fine-powdering of each of the first part and the second part of the dried ginseng to 1000mesh to 1100mesh. When it is finely powdered as described above, it is finely powdered having an average particle size of about 13 μm, and may be powdered to a size suitable for production as an orally disintegrating film or suitable for absorption into the human body.

The fine powdering step (S50) can be made by putting the raw material into a rotary container and pulverizing it using an ultrafine particle grinder, a cyclone, a rotary bag filter, and the like. Preferably, an ultra-fine grinder may be most suitable for preventing the incorporation of impurities (iron powder) that may occur during fine grinding and grinding with 1,000 mesh to 1100 mesh. If the ginseng powder is not refined in the production of an oral disintegrating film by adding ginseng fine powder and other raw materials, the film may have a rough surface in terms of physical properties and a foreign body sensation may be felt in the mouth. It can be finely powdered. In the case of the present invention, by producing fine ginseng powder in the range of 1,000 mesh to 1100 mesh, it is possible to increase marketability by facilitating absorption into the human body while maximally adding a soft feeling in the mouth.

In the case of the present invention, it is possible to increase the absorption rate in the human body by pulverizing the ginseng cultivated as described above, and since it does not use a separate extraction method, most of the active ingredients of ginseng can be utilized. For example, when ginseng is finely powdered to the same size as described above, the absorption power can be increased by about 2.5 times compared to when simply taking the whole ginseng itself.

On the other hand, with reference to FIG. 2, when specifically explaining the culturing step (S20) of the present invention, the first step (S201) of freezing the two-year-old seedlings in a temperature range of -4 ℃ to -1 ℃, After the first step, the second step (S202) of aging in a temperature range of 4°C to 6°C, the third step (S203) of washing the seedlings after the second step (S203), and after the third step, the seedlings are placed on a plate A fourth step of planting (S204), a fifth step (S205) of growing by lighting an LED when the sprouts germinate on the seedlings after the fourth step (S205), and a step (S206) of harvesting the grown ginseng after the fifth step (S206) characterized in that

In the first step (S201), the two-year-old ginseng seedlings are stored frozen in a temperature range of -4°C to -1°C, and can be frozen by spreading evenly so that there is no compression during freezing. Meanwhile, the first step (S201) may be performed for 2 to 8 months. By going through the freezing step of the first step (S201) as described above, it is possible to force the seedlings to take winter hibernation, and to promote growth to maintain an optimal state during cultivation of seedlings.

In the second step (S202), the frozen seedlings are taken out and aged in a temperature range of 4°C to 6°C. By freezing the seedlings as described above, it is possible to forcibly produce the same effect as wintering, and by going through the step of aging in the above temperature range, plant growth hormones are evenly generated, thereby helping the seedlings to germinate. Meanwhile, the second step ( S202 ) may be performed for 3 to 7 days.

The third step (S203) is a step of washing the seedlings, and heavy metals, fungi, viruses, pesticides, etc. present in the seedlings can be removed by the third step (S203). The third step (S203) is a first washing step of high-pressure washing using water, a second washing step of immersing in water in a temperature range of 20°C to 30°C for 15 minutes to 35 minutes, and the water of the second washing step It may be characterized in that it comprises a third washing step of immersing in water in the temperature range of 20 ℃ to 30 ℃ for 1 hour to 2 hours to exchange the. As described above, heavy metals, fungi, viruses, pesticides, etc. present in seedlings can be substantially completely removed by washing in three steps as described above. On the other hand, it may further comprise spraying the seedlings in the fifth step after storing the water used in the third washing step at a temperature range of 4 ℃ to 6 ℃. The water used in the third washing step may have practically no impurities present in the seedlings, and the active ingredients of the seedlings may remain in the third washing step. It can help with growth.

In the fourth step (S204), after fixing the planting plate upside down, the brain heads of the seedlings are planted in the grooves formed in the planting plate with the brain heads facing down, and water is sprayed on the whole seedlings after planting, characterized in that can do. When planting ginseng seedlings on the planting plate, a planting sponge is inserted into the groove formed in the planting farm, and a partially cut portion may be included so that the seedlings can be placed. When the seedlings are planted on the planting plate, the brain head of the seedlings is exposed to the outside of the planting plate while facing downward, and the remaining part, the root part, is exposed to the outside while facing the top, so that the sprayed moisture can be contained.

On the other hand, after the seedlings are planted on the planting plate, the root part is directed downward, and the planting plate is mounted on the chamber bed to perform cultivation of the seedlings. To this end, water is sprayed on both the root part and the brain head part of the seedlings every 3 hours for about 1 minute 30 seconds to 2 minutes 30 seconds using a sprayer, so that the sprouts of the seedlings can germinate.

Next, the fifth step (S205) is a step 5-1 of continuously supplying moisture to the seedlings in a dark state and stopping the supply of moisture when the sprouts of the seedlings germinate to a size of 8 cm to 12 cm. After step -1, the supply of moisture to the sprout of the seedlings is stopped and the LED is turned on for 19 to 21 hours a day in a state of supplying moisture in a temperature range of 12° C. to 15° C. only to the root part of the seedlings. -Step 2, and Step 5-3 repeating Step 5-2 for 23 to 27 days.

In step 5-1, water can be sprayed on both the root and brain head parts of the seedlings every 3 hours for about 1 minute 30 seconds to 2 minutes 30 seconds using a sprayer, and the sprouts of seedlings germinate to a size of 8 cm to 12 cm. This can stop the supply of moisture. In step 5-2, the LED is turned on for 19 to 21 hours a day in a state of stopping the supply of moisture to the sprout part of the seedling and supplying moisture in the temperature range of 12°C to 15°C only to the root part of the seedling. can In addition, the LED may not be turned on for 3 to 5 hours a day. During this period, both the sprout and the root of seedlings can be supplied with moisture, but while the LED is turned on, water is supplied to the sprout of seedlings. It is preferable not to If moisture is supplied to the sprout of ginseng while the LED is turned on, the light is irradiated as the moisture is supplied to the leaves of the ginseng, and leaf blight may occur.

On the other hand, when supplying moisture in a temperature range of 12 ° C to 15 ° C to the root part of seedlings, if moisture is supplied in a temperature range of less than 12 ° C, it may suffer cold damage, and moisture is supplied in a temperature range of more than 15 ° C. In this case, root diseases such as soft blight or mold may occur in the root of seedlings. Therefore, the temperature range of the moisture supplied to the root part of seedlings is most preferably in a temperature range of 12°C to 15°C.

On the other hand, by going through the cultivation step (S20) as described above, it is possible to perform the step of harvesting the cultivated ginseng by going through a cultivation period of 25 to 45 days after starting cultivation for two-year-old seedlings. When ginseng is harvested, cut about 1 cm above the brain head, and the first part composed of leaves and stems and the second part composed of brain heads and roots can be separated.

Meanwhile, FIG. 3 is a flowchart schematically illustrating a method for manufacturing a health functional food including ginseng active ingredient according to an embodiment of the present invention.

Referring to Figure 3, the health functional food manufacturing method according to an embodiment of the present invention comprises the steps of preparing two-year-old seedlings (S10), cultivating the two-year-old seedlings by a spray-watering hydroponics method (S20), Separating the cultivated ginseng with a first part composed of leaves and stems and a second part composed of brain heads and roots (S30), and drying the first part and the second part of the ginseng separately with microwaves, respectively. (S40), finely pulverizing the first part and the second part of dried ginseng to 1000mesh to 1100mesh to prepare a fine ginseng powder (S50) and the fine ginseng powder, zinc oxide, tocopherol and vitamin B12 Including the step of mixing (S60), but the culturing step, the first step of freezing the two-year-old ginseng seedlings in a temperature range of -4 ℃ to -1 ℃, after the first step 4 ℃ to 6 ℃ The second step of aging in the temperature range, the third step of washing the seedlings after the second step, the fourth step of planting the seedlings on a planting plate after the third step, and the sprouts germinate on the seedlings after the fourth step It is characterized in that it comprises a fifth step of growing by turning on the LED and harvesting the grown ginseng after the fifth step.

In the mixing step (S60), the zinc oxide may be absorbed into the human body to reinforce immunity. Zinc is present in the brain, heart, muscle, liver and bone tissue in the human body, and is an essential trace mineral for various functions in the body such as cell growth, reproductive maturity, and immunity. contains about 60%. Zinc deficiency can cause immune diseases such as atodermatitis, asthma, allergic rhinitis, allergic conjunctivitis, and urticaria. may play a deterrent role. Infectious diseases as described above are closely related to T cells. Zinc plays a major role in cellular immunity and is related to these thymus and T cells. Therefore, zinc intake can be said to be the key to immune health.

In addition, zinc is involved not only in immunity but also in cell metabolism, energy metabolism, and synthesis of various hormones. For example, zinc helps the action of antioxidant enzymes in the body that suppress free radicals, protects cell tissues from oxidative stress and helps repair DNA. Most research papers show that zinc, calcium, and magnesium are relatively deficient in minerals such as zinc, calcium, and magnesium when testing minerals for chronic diseases such as atopic dermatitis and rheumatoid arthritis, suggesting that zinc plays a very important role in our body. In addition, NF-Kb, which is mainly synthesized in the liver, is a key conductor of the natural immune/inflammatory response. Zinc supplementation reduces the activity of this protein complex, so it can be effective in rheumatoid arthritis, atopy, asthma, and acne, which are hypersensitive inflammatory reactions. As such, zinc is involved in the activity of 200 kinds of enzymes and protein synthesis, so it has a useful function for hair health, hair loss, and growth. Zinc also helps male sexual function and muscle building. There is 10 times more zinc in the prostate than other tissues. The prostate is an organ that produces and secretes a large amount of citric acid, and zinc plays a role in preventing the oxidation of citric acid. For example, in patients with prostate cancer, zinc intake is important because a decrease in zinc can promote the growth of cancer cells.

In addition, zinc activates sperm motility, helps to promote spermatogenesis, and improves immune function in diabetic patients. For example, in diabetic patients, the urine excretion amount of zinc increases and the blood zinc concentration is reduced, and it promotes autoimmune destruction of beta cells in juvenile diabetic patients, thereby reducing the zinc concentration or reducing the antioxidant enzyme. Zinc intake is important because it can develop into diabetes complications caused by an increase in the back.

For all of the above reasons, the intake of zinc, which is not produced in the body, must be taken from the outside, but there is a limit to ingestion of vitamins, minerals, minerals, etc. as food. In other words, it can be seen that there is a limit to the intake of zinc, which has a low absorption rate in the body through food due to the depletion of food nutrients. In the present invention, by mixing the fine ginseng powder and zinc oxide as described above, zinc that is not produced in the human body and is essential for health, immunity, and antioxidant effects can be supplemented. The zinc oxide may be, for example, zinc gluconate.

On the other hand, the tocopherol is a kind of antioxidant, it can have an effect similar to vitamin C, thereby preventing aging and improving blood circulation. However, in the case of vitamin C, side effects and gastrointestinal disturbances may occur to people with a cold intestine, but tocopherol is very effective because it can work without such side effects. The representative pharmacological action of tocopherol is to inhibit the action of free radicals that cause body aging and cancer. In addition, it acts as a powerful antioxidant that inhibits the oxidation of various cells, reduces damage to the skin and hair in our body, helps blood circulation, and helps to keep skin capillaries strong. Symptoms of hormonal imbalance include premenstrual syndrome, weight gain, allergies, urinary tract infections, and fatigue.

In addition, tocopherol lowers the level of LDL cholesterol, which has a harmful effect on the body, and at the same time increases the level of HDL, thereby preventing cardiovascular diseases such as arteriosclerosis and heart disease. In the case of women, when the balance of hormones is disturbed, there is a problem with blood circulation. Intake of tocopherol can help maintain body temperature, help blood circulation, and help hormone production to relieve menstrual pain and menstrual irregularities. In addition, it protects brain cells from damage caused by oxidation and prevents the brain from aging, helping brain health and helping to treat Alzheimer's. In addition, it inhibits macular degeneration and has the effect of preventing cataracts and improving eyesight. In the case of the present invention, by mixing the fine ginseng powder and tocopherol as described above, it is possible to produce useful effects on the human body as described above.

On the other hand, the vitamin B12 can suppress damage to the nervous system, relieve numbness in the hands and feet, neuralgia, and prevent the depletion of vitamin B12 in patients with gastrointestinal or diabetes mellitus while supplementing the vitamin B12. Vitamin B12 is a coenzyme involved in DNA synthesis, amino acid and fat metabolism, and is indirectly involved in the synthesis of intracerebral messengers. For example, patients who have had their stomach resected or who have developed stomach cancer need vitamin B12 because vitamin B12 is not absorbed into the body when the stomach is resected. Vitamin B12 is also effective for sleep disorders as it stimulates the production of the sleep-regulating hormone melatonin. The daily requirement is 3~5 ug, which is a very small amount, but extreme vegetarians who do not eat meat can easily be deficient. Deficiency can cause neurological damage as well as pernicious anemia. As such, vitamin B12 may play an important role in the function and maintenance of nerve cells. The vitamin B12 may be, for example, cyanocobalamin.

In the present invention, by mixing the fine ginseng powder as described above with zinc oxide, tocopherol and vitamin B12, various effects useful for the human body as described above can be produced.

The mixing step further comprises a film-forming component, and after the mixing step, the mixture is applied on a release film and dried to prepare an orally disintegrating film substrate. Accordingly, it is possible to prepare an orally disintegrating film that is easily ingested. In the case of the present invention, it is not a method of extracting active ingredients from ginseng, but using all of the brain heads, roots, stems, and leaves of ginseng, drying and fine powdering them through microwaves to utilize most of the active ingredients without loss of active ingredients. Orally disintegrating film can be prepared. In addition, it is possible to increase the absorption rate in the human body by the orally disintegrating film, and to be easily ingested. In order to prepare the orally disintegrating film, the fine ginseng powder can be prepared by finely pulverizing the first part and the second part of ginseng into 1000mesh to 1100mesh, and when the amount is less than 1000mesh, when preparing an orally disintegrating film The uniformity may be lowered, and the absorption rate may be lowered. In addition, in the case of 1100 mesh or more, a large amount of fine ginseng powder may be lost due to the flying of the powder during the oral disintegration film manufacturing process, or agglomeration may occur during the preparation of the mixture, which may not be suitable for the mass production process.

When preparing an orally disintegrating film base, the mixing step (S60) includes fine ginseng powder in the range of 22 wt% to 27 wt%, zinc oxide in the range of 0.2 wt% to 0.6 wt%, 0.7 based on the total weight of the mixed mixture Tocopherol in the range of weight % to 1.1% by weight, vitamin B12 in the range of 0.1% to 0.2% by weight, solvent and other additives in the range of 55% to 65% by weight.

In the content range of the fine ginseng powder, it may have a saponin content that can have a useful effect on the human body, and while increasing the compatibility in the content range of zinc oxide, it can have a useful effect on the human body. When the content of zinc oxide is less than 0.2% by weight, functions such as immunity and antioxidant effects obtained from zinc oxide may not be obtained. In addition, while increasing the compatibility in the content range of the tocopherol, it is possible to produce a useful effect on the human body. When the content of tocopherol is less than 0.1% by weight, functions such as blood circulation obtained from tocopherol may not be obtained, and if it exceeds 1.1% by weight, compatibility is deteriorated, and unnecessary excessive intake may occur. In addition, while increasing the compatibility in the content range of the vitamin B12, it is possible to produce a useful effect on the human body. If the content of the vitamin B12 is less than 0.1% by weight, it may not be able to function and maintain the function of nerve cells obtained from vitamin B12. . In addition, in the content range of the solvent, it is possible to uniformly mix the above components.

In the case of preparing an orally disintegrating film base, fine ginseng powder in the range of 55 wt% to 65 wt%, zinc oxide in the range of 0.5 wt% to 1.5 wt%, 1.5 to the total weight of the dried solids of the prepared orally disintegrating film base It may be characterized as comprising tocopherol in the range of weight % to 2.5% by weight, vitamin B12 in the range of 0.2% by weight to 0.4% by weight, other additives and film-forming ingredients.

On the other hand, the method of producing the orally disintegrating film is, for example, hydroxypropylmethylcellulose, pullulan, polyvinyl acetate, polyethylene oxide, gelatin, alginic acid, pectin, starch, casein, gluten, acacia gum, etc. A variety of polymers can be used. In addition, other additives may include thickeners, emulsifiers, plasticizers, solubilizers, sweeteners, flavoring agents, defoamers, preservatives, pH adjusters, lubricants, and the like. It can be prepared by mixing these components and the above mixture, homogenizing, discharging these mixtures on a release film, molding the mixture, and then drying.

The plasticizer may be at least one selected from the group consisting of D-sorbitol, glycerin, glycerol oleate, polyethylene glycol, propylene glycol, saccharides, sugar alcohols and triacetin. In addition, the sweetener may be at least one selected from the group consisting of enzyme-treated stevia, sorbitol solution, sucralose, sodium chloride, mannitol, aspartame, acesulfame salt, saccharin salt, neotime, cyclamate salt, and thaumatin. In addition, the flavoring agent may be herbal flavor, ginseng flavor, etc., for example, may be a natural flavor, artificial flavor, or a mixture thereof. In addition, the solubilizing agent may be polysorbate 80. The solvent is purified water, alcohol, alkyl acetate, dimethylformamide, dimethyl sulfoxide, acetone, anisole, acetic acid, butylmethyl ether, ethyl ether, ethyl formate, formic acid, pentane, heptane, methyl ethyl ketone and methyl isobutyl ketone. It may be at least one selected from the group consisting of. The solvent may be included in the range of 50 wt% to 70 wt% with respect to the total mixture of the solvents.

The antifoaming agent removes air bubbles, and may be decanoic acid, lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, or the like. In addition, the preservative may be hydrogen peroxide, sodium hypochlorite, high bleaching powder, bleaching powder, benzoic acid or its sodium salt, sorbic acid or its sodium or potassium salt, sodium dihydroacetate, propionic acid or its calcium or sodium salt. In addition, the pH adjusting agent, the lubricant is at least one selected from the group consisting of talc, stearic acid, magnesium stearate, colloidal silicon dioxide and sodium stearyl fumarate, glyceryl behenate, and glyceryl distearate. can Without limitation, solvents and other additives may use various components widely used in the art in addition to the above components.

Meanwhile, the above-described film-forming components and other additives are well known in the art, and detailed descriptions thereof will be omitted.

Figure 4 is a schematic plan view of the orally disintegrating film according to an embodiment of the present invention is shown. Referring to FIG. 4, it is an orally disintegrating film prepared by the above-described health functional food manufacturing method, wherein the orally disintegrating film is formed on the release film 100 and the release film 100, and the mixture of the mixture is formed therein. Including an oral disintegrating film base 200 that contains an active ingredient and dried, the orally disintegrating film base 200 is formed in a plurality of spaced apart from each other on the release film 100 on a horizontal cross-section, and adjacent to each other oral cavity It is characterized in that between the disintegrating film substrate 200 is separated by an oblique line (300).

In the case of the orally disintegrating film of the present invention, a plurality of orally disintegrating film substrates 200 containing the above-described active ingredients are formed in one release film 100, and the orally disintegrating film substrate 200 is formed into a plurality of pieces. They are spaced apart to improve productivity. In addition, by being separated (300) by an oblique line between the adjacent orally disintegrating film substrate 200, the user can easily separate and use one orally disintegrating film substrate 200. That is, as shown in FIG. 4, when the gap between the orally disintegrating film substrate 200 is separated (300) by an oblique line, one orally disintegrating film substrate 200 is separated from the release film 100 and ingested. By peeling off by applying force to the sharp part, the orally disintegrating film substrate 200 can be separated more easily.

Specifically, the orally disintegrating film substrate 200 is a horizontal cross-sectional shape of a single orally disintegrating film substrate 200 while a plurality of orally disintegrating film substrates 200 are spaced apart from each other on the release film 100, respectively. The shape of this parallelogram may be characterized in that the orally disintegrating film base 200 is disposed so that all long diagonals of the parallelogram are parallel to the same direction. When disposed in this way, the release film 100 is disposed long and the oral disintegration film can be formed in the form of a roll, which will be described below, while orally disintegrating from the release film 100 through the corner portion of the parallelogram. The film base 200 can be easily separated and ingested.

The orally disintegrating film may be characterized in that the release film 100 and the orally disintegrating film base 200 are configured in a roll form. By rolling the orally disintegrating film in the form of a roll, the orally disintegrating film base 200 can be interposed on both the upper and lower surfaces of the release film 100, and the orally disintegrating film base 200 You can use it by peeling off the roll as you consume it gradually. Therefore, it is easy to store, and it is possible to effectively prevent the orally disintegrating film base 200 from being damaged.

Non-limitingly, the preparation of the orally disintegrating film is prepared by preparing the release film 100, and applying the mixture according to the shape of the orally disintegrating film base 200 by dividing it on the release film 100 and drying, or releasing it. It may be manufactured by disposing a mask having an empty space formed thereon according to the shape separated by an oblique line 300 on the upper portion of the film 100 in advance, and applying a mixture thereon. In addition, it may be manufactured by, without limitation, applying the mixture to the release film 100 and then drying the mixture after undergoing a process of removing it according to the shape of the spaced diagonal line 300 .

Although the embodiments of the present invention have been described in detail above, the scope of the present invention is not limited thereto, and it is understood that various modifications and variations are possible within the scope without departing from the technical spirit of the present invention described in the claims. It will be apparent to those of ordinary skill in the art.

100: release film
200: Orally disintegrating film base
300: spaced part between the orally disintegrating film substrates

Claims (14)

delete delete delete delete delete delete delete Preparing two-year-old seedlings;
Cultivating the two-year-old seedlings by a spray-watering hydroponics method;
separating the cultivated ginseng from a first part composed of leaves and stems and a second part composed of brain heads and roots;
drying the first part and the second part of the ginseng separately with microwaves;
preparing a fine ginseng powder by finely pulverizing the first part and the second part of dried ginseng to 1000mesh to 1100mesh;
mixing the fine ginseng powder, zinc oxide, tocopherol, vitamin B12, a solvent, a film forming component and other additives; and
After the mixing step, the mixture is applied on a release film and dried to prepare an orally disintegrating film substrate,
The cultivating step is
A first step of freezing the two-year-old ginseng seedlings in a temperature range of -4 ℃ to -1 ℃; a second step of aging in a temperature range of 4°C to 6°C after the first step; a third step of washing the seedlings after the second step; a fourth step of planting the seedlings on a planting plate after the third step; A fifth step of growing by lighting an LED when the sprouts germinate in the seedlings after the fourth step; and a ginseng active ingredient comprising the step of harvesting the ginseng grown after the fifth step,
The first step is performed for 2 to 8 months, the second step is performed for 3 to 7 days,
The third step is a first washing step of high-pressure washing using water, a second washing step of immersing in water in a temperature range of 20°C to 30°C for 15 minutes to 35 minutes, and exchanging the water of the second washing step. A third washing step of immersing in water in a temperature range of 20 ° C to 30 ° C for 1 hour to 2 hours,
It further comprises spraying the seedlings in the fifth step after storing the water used in the third washing step at a temperature range of 4°C to 6°C,
In the fourth step, after fixing the planting plate upside down, the brain heads of the seedlings are planted in the grooves formed in the planting plate, and water is sprayed on the whole seedlings after planting, characterized in that,
The fifth step is a 5-1 step of continuously supplying moisture to the seedlings in a dark state and stopping the supply of moisture when the sprouts of the seedlings germinate to a size of 8 cm to 12 cm; After the 5-1 step, the LED is turned on for 19 to 21 hours a day in a state in which the supply of moisture to the sprout of the seedlings is stopped and moisture in the temperature range of 12°C to 15°C is supplied only to the root part of the seedlings. Step 5-2; and a 5-3 step of repeating the 5-2 step for 23 to 27 days.
The film-forming component includes at least one component selected from hydroxypropylmethylcellulose, pullulan, polyvinyl acetate, polyethylene oxide, gelatin, alginic acid, pectin, starch, casein, gluten and acacia gum,
The other additives are thickeners, emulsifiers, plasticizers, solubilizers, sweeteners, flavoring agents, defoamers, preservatives, health functional food manufacturing method comprising at least one component selected from a pH adjuster and a lubricant. delete 9. The method of claim 8,
The mixing step includes fine ginseng powder in the range of 22 wt% to 27 wt%, zinc oxide in the range of 0.2 wt% to 0.6 wt%, tocopherol in the range of 0.7 wt% to 1.1 wt%, 0.1 wt% relative to the total weight of the mixed mixture % to 0.2% by weight of vitamin B12, a solvent in the range of 55% to 65% by weight, and a film-forming component and other additives in the remaining amount A method for manufacturing a health functional food comprising an active ginseng ingredient. 11. The method of claim 10,
Fine ginseng powder in the range of 55 wt% to 65 wt%, zinc oxide in the range of 0.5 wt% to 1.5 wt%, tocopherol in the range of 1.5 wt% to 2.5 wt%, based on the total weight of the dried solid content of the prepared orally disintegrating film base , A method of manufacturing a health functional food comprising an active ingredient in ginseng, characterized in that it contains vitamin B12 in the range of 0.2% by weight to 0.4% by weight and the remaining amount of the film forming component and other additives. It is an orally disintegrating film comprising an orally disintegrating film base prepared by the method of any one of claims 8, 10 and 11,
The orally disintegrating film is a release film; and an orally disintegrating film base formed on the release film and dried by including the active ingredient of the mixture therein,
Orally disintegrating film comprising ginseng active ingredient, characterized in that the orally disintegrating film substrate is formed in a plurality of spaced apart from each other on the release film in a horizontal cross-section, and is separated by an oblique line between adjacent orally disintegrating film substrates . 13. The method of claim 12,
The orally disintegrating film is an orally disintegrating film, characterized in that the release film and the orally disintegrating film substrate are configured in a roll form. 14. The method of claim 13,
The orally disintegrating film substrate is a horizontal cross-sectional shape of a single orally disintegrating film substrate while a plurality of orally disintegrating film substrates are spaced apart from each other on the release film and each has a parallelogram shape,
Oral disintegrating film, characterized in that the orally disintegrating film substrate is disposed so that the long diagonals of the equilibrium quadrilateral are all directed in parallel in the same direction.

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