KR102306745B1 - Moisturizing composition comprising ardisia crenata extract and aneilema keisak extract as an effective ingredient - Google Patents

Abstract

The present invention relates to a moisturizing composition comprising a platinum extract and a mantis plant extract as active ingredients. A moisturizing composition comprising, as an active ingredient, a platinum extract and a mantis plant extract, which are an aspect of the present invention, may exhibit an excellent skin moisturizing effect by enhancing the skin's moisture retention and skin barrier function. In addition, the composition contains a plant extract, which is a natural product harmless to the human body, as an active ingredient, and does not cause skin trouble.

Description

Moisturizing composition comprising platinum extract and mantis plant extract as active ingredients

The present invention relates to a moisturizing composition comprising a platinum extract and a mantis plant extract as active ingredients.

The skin is the outermost part of the body and has the function of protecting the human body. Specifically, the skin plays a role in preventing the loss of water and electrolytes in our body and protecting it from the penetration of foreign substances.

The skin is divided into an epidermal layer, a dermis layer, and a subcutaneous fat layer. In relation to the function of preventing moisture loss of the skin, the outermost stratum corneum of the epidermis is composed of keratinocytes and intercellular lipids, and the stratum corneum prevents moisture loss to the outside. In addition, the skin barrier located in the stratum corneum is composed of ceramide, fatty acid, and cholesterol, and has a function of inhibiting the penetration of foreign substances and preventing transepidermal water loss (TEWL). In addition, it is known that Natural Moisturizing Factor (NMF) is present in the stratum corneum and plays an important role in moisturizing the skin.

On the other hand, a person's skin generally becomes dry gradually with age. However, in recent years, despite the young age, chronic exposure to air pollution, dry environment, ultraviolet rays, chemicals, etc., the number of people suffering from chronic dry skin symptoms is increasing.

In order to solve this problem, various types of moisturizing substances have been developed. For example, artificial moisturizing substances such as lithium chloride, sodium hexametaphosphate, polydextrose, and alpha hydroxy acid, and natural moisturizing agents such as aloe extract, honey, and hyaluronic acid are being developed. In the past, artificial moisturizing substances were commonly used, but recently, as research results that artificial chemical substances cause skin troubles follow, preference for substances derived from natural substances is increasing. However, the moisturizing substances derived from natural substances developed so far have a limitation in that the moisturizing effect is inferior to that of the artificial moisturizing substances. Accordingly, there is a need to develop a moisturizing substance derived from a natural product having an excellent moisturizing effect.

KR 10-2032873 B1

In one aspect, an object of the present invention is to provide a moisturizing composition having an excellent moisturizing effect.

In one aspect, an object of the present invention is to provide a safe moisturizing composition without skin toxicity.

In order to achieve the above object, the present invention, in one aspect, provides a moisturizing composition comprising a platinum extract and a mantis plant extract as active ingredients.

A moisturizing composition comprising, as an active ingredient, a platinum extract and a mantis plant extract, which are an aspect of the present invention, may exhibit an excellent skin moisturizing effect by enhancing the skin's moisture retention and skin barrier function. In addition, the composition contains a plant extract, which is a natural product harmless to the human body, as an active ingredient, and does not cause skin trouble.

Hereinafter, the present invention will be described in detail.

Hereinafter, each configuration will be described in more detail, but this is only an example, and the scope of the present invention is not limited by the following content.

In one aspect, the present invention is platinum ( Ardisia crenata ) extract; And mantis grass ( Murdannia keisak ) It is a moisturizing composition comprising an extract as an active ingredient.

Platinum ( Ardisia crenata ) is a vascular plant of the genus Rhododendron Primaceae. Baekryanggeum is widely distributed from southeast Asia to India, and in Korea, it is mainly grown on islands in the southern provinces. The height of Platinum is about 60cm, and the flowers are white, and small flowers run in coaxial inflorescences at the tip of small branches in summer. The fruits are ball-shaped and ripen with a red color in winter. The root of platinum is known to have the effect of inhibiting E. coli and Pseudomonas aeruginosa and having a contraceptive effect.

Mantis grass ( Murdannia keisak ) is a plant of the genus Mantis. It grows near water or wetlands, the stem is about 20cm high, branches are split at the bottom, and lobe, and the root of the beard comes out from each node. The stem is yellow and has one hairline, and the leaves are alternate phyllotaxis, narrow lanceolate, and the lower part has a short sheath. Flowers are light reddish-purple, hanging one at a time from the leaf axil in August-September, with stems, and three calyx pieces, membranous, and green. The fruit is produced around October and is about 1cm long and has an oval shape. It splits into 3 parts and a small seed comes out. Mantis grass is known to have the effect of improving inflammation such as sore throat and hepatitis, diuretic action, and tumor improvement effect.

As used herein, the term "extract" includes all substances obtained by extracting components therein from natural products, irrespective of the extraction method or types of components. For example, it is a concept in a broad sense including all of those obtained by extracting a component soluble in a solvent from a natural product using water or an organic solvent, and a product obtained by extracting only a specific component of a natural product.

In one aspect, the extract of platinum and mantis grass may include each of a fruit extract, a stem extract, a leaf extract, or an underground extract, and may include an extract of a whole plant.

By including a combination of platinum extract and mantis grass, the composition may exhibit a significantly superior moisturizing effect compared to the case where only one of them is included.

In one aspect, the platinum extract and the mantis grass extract, when the platinum extract is 100 parts by weight, the mantis extract may be included in an amount of 10 to 500 parts by weight. Preferably, when the platinum extract is 100 parts by weight, the mantis grass extract is 30 to 400 parts by weight, more preferably 50 to 350 parts by weight, more preferably 70 to 330 parts by weight, and more preferably 100 parts by weight. It may be included in ~300 parts by weight.

When the platinum extract and the mantis plant extract are included in the same weight ratio as described above, the most excellent moisturizing effect can be obtained from the platinum extract and mantis plant extract combination.

The platinum extract and mantis grass extract may be included in an amount of 0.0001 to 10% by weight, based on the total weight of the composition.

As the extraction method of the extract, physical, chemical, enzymatic methods, etc. may be used, for example, steam extraction method, steam distillation method, solvent extraction method, supercritical fluid extraction method, mechanical compression extraction method, microwave application extraction method, enzyme extraction method, etc. can be used. have.

In the above aspect, the extraction method of the extract may preferably be a solvent extraction method.

In addition, the extraction solvent of the extract may include water, an organic solvent or an organic solvent aqueous solution.

When the solvent of the extract is water, it may include a cold water extract or a hot water extract.

_{The organic solvent is not particularly limited, and C 1-5} lower alcohols such as methanol, ethanol, isopropyl alcohol, n-propyl alcohol, n-butanol and isobutanol, glycerol, ethylene glycol, propylene glycol, 1, Polyhydric alcohols such as 3-butylene glycol, hydrocarbon solvents such as methyl acetate, ethyl acetate, benzene, n-hexane, diethyl ether, dichloromethane, chloroform, petroleum ether, methyl acetate, benzene, hexane, chloroform, methylene It may be a non-polar organic solvent such as chloride, dimethyl ether, ethyl acetate, and the like.

In one aspect, the concentration of the organic solvent aqueous solution may be 1 ~ 90% (v / v).

In one embodiment, when the organic solvent is alcohol, the concentration of the organic solvent is 50 to 90% (v/v), preferably 60 to 80% (v/v), more preferably 65 to 75% (v). /v). When the concentration of the organic solvent is the same as above, it is possible to most effectively extract the active ingredient from the extraction target platinum and mantis grass.

In one aspect, the composition may be a cosmetic composition.

In one aspect, the cosmetic composition is, skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nourishing lotion, massage cream, nourishing cream, moisture cream, hand cream, foundation, essence, nourishing lotion, It may be any one or more selected from the group consisting of packs, soaps, cleansing foams, cleansing lotions, cleansing creams, body lotions and body cleansers.

The cosmetic composition may contain a cosmetically acceptable medium or base. It is in any formulation suitable for topical application, for example solutions, gels, solid or kneaded dry products, emulsions obtained by dispersing the oily phase in an aqueous phase, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) and/or It may be provided in the form of a non-ionic vesicular dispersant, or in the form of a cream, skin, lotion, powder, ointment, spray or concealer stick. These compositions can be prepared according to conventional methods in the art.

When the formulation of the present invention is a solution or emulsion, a solvent, solubilizer or emulsifier is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 ,3-butylglycol oil, glycerol fatty esters, fatty acid esters of polyethylene glycol or sorbitan.

When the formulation of the present invention is a suspension, as a carrier component, a liquid diluent such as water, ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, microcrystals Adult cellulose, aluminum metahydroxide, bentonite, agar or tracanth may be used.

When the formulation of the present invention is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as a carrier component. can

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component, and in particular, in the case of a spray, additional chlorofluorohydrocarbon, propane /may contain propellants such as butane or dimethyl ether.

The cosmetic composition may additionally contain a thickener. The thickener included in the cosmetic composition of the present invention is, for example, methyl cellulose, carboxy methyl cellulose, carboxy methyl hydroxy guanine, hydroxy methyl cellulose, hydroxyethyl cellulose, carboxy vinyl polymer, polyquaternium, cetearyl alcohol, stearate Ric acid, carrageenan, etc. can be used.

In addition, the cosmetic composition may contain various suitable bases and additives as necessary, and the types and amounts of these components can be easily selected by the inventor. If necessary, it may contain acceptable additives, for example, may further include components such as preservatives and pigments conventional in the art.

In addition, the compounding component which may be added other than this is not limited to this, Moreover, any said component can be mix|blended within the range which does not impair the objective and effect of this invention.

Hereinafter, a formulation example of the composition according to the present invention will be described, but the cosmetic composition can be applied in various formulations, which is not intended to limit the present invention, but merely to describe it in detail.

<Formulation Example 1> Preparation of essence

Essence was prepared using the following formulation.

[Table 1]

<Formulation Example 2> Preparation of softening lotion

Sodium hyaluronate was prepared as a 1% solution by dispersing it in purified water with a propeller mixer (3000 rpm). Raw materials 1 to 8, excluding sodium hyaluronate, were homogenized at 500 rpm in an aqueous dissolution tank using a propeller mixer, heated at 75° C. to completely dissolve, and then cooled to room temperature. Then, after completely dissolving the raw materials 9 to 11 in a separate dissolution tank, it was put into the aqueous dissolution tank and stirred and mixed. Here, the platinum extract and mantis grass extract of Example were added and thoroughly stirred and mixed to prepare a softened lotion.

[Table 2]

<Formulation Example 3> Preparation of nutrient lotion

The carbomer was dispersed at 4000 rpm using a propeller mixer to prepare a 2% solution. Raw materials 1 to 6 were added to an aqueous dissolution tank, stirred and dispersed with a homomixer (2000 rpm), and then heated to 75°C. Raw materials 7 to 14 were put into an oil phase dissolution tank and dissolved by heating to 75°C. Then, the dissolved oil phase was put into the aqueous dissolution tank to emulsify (3000 rpm/5 min), and then cooled to room temperature. Here, the mixed extract of Example was added and sufficiently stirred and mixed to prepare a nutrient lotion.

[Table 3]

<Formulation Example 4> Preparation of pack

Raw materials 1 to 8 were completely dissolved in a separate dissolution tank, stirred and mixed, and platinum extract and mantis grass extract were added thereto, followed by sufficiently stirring and mixing to prepare a pack.

[Table 4]

<Formulation Example 5> Preparation of cleansing foam

After dispersing and dissolving the aqueous phase and the oil phase, respectively, mixing and saponification, and cooling to room temperature, a cleansing foam was prepared.

[Table 5]

Hereinafter, the present invention will be described in more detail through examples. These examples are only for illustrating the present invention, and it will be apparent to those of ordinary skill in the art that the scope of the present invention is not to be construed as being limited by these examples.

[Production Example]

[Preparation Example 1] Preparation of Platinum extract, Mantis grass extract

500 ml of 70% ethanol was added to 50 g of each of the washed Platinum and Mantis grass, and immersed at room temperature for 24 hours, and the extract was filtered with filter paper. The filtered filtrate was evaporated through a concentrator and then freeze-dried to prepare extracts of platinum and mantis grass, respectively.

[Preparation Example 2] Preparation of essence

Essences were prepared using the formulations described in Table 6.

[Table 6]

[Experimental example]

The moisturizing effect of Platinum and Mantis plant extract was confirmed through an experiment to confirm the skin moisture increase rate and skin barrier improvement effect.

The content ratios of the platinum extract and mantis grass extract used in the experiment were as described in Tables 7 and 8 below. What is shown in Tables 7 and 8 means the content ratio of the Platinum extract and Mantis grass extract, and the total weight of the two extracts is 3% by weight.

In addition, when only the platinum extract was included, it was set as Comparative Example 3, and when only the Mantis grass extract was included, it was set as Comparative Example 4.

[Table 7]

[Table 8]

[Experimental Example 1] Measurement of skin moisture increase rate

10 women aged 20 to 40 years with similar skin condition (moisture) were selected for each group (Example and Comparative Example), and the essence prepared by adding Examples and Comparative Examples according to the formulation in Table 5 was administered twice daily ( evening) and applied to the entire face for 15 days. At this time, before applying the essence, the dryness of the skin is measured using a moisture meter (corneometer, CM820 courage Khazaka electronic GmbHtk, Germany) under constant temperature and humidity conditions (24℃, 40% humidity) in advance, and this is set as a default value, After 15 days had elapsed, the amount of skin moisture was measured to evaluate the amount of change.

As a result, it was found that the skin moisture increase rate was excellent when both the Platinum extract and the Mantis plant extract were used. was confirmed (Table 9).

[Table 9]

[Experimental Example 2] TEWL (Transepidermal water loss) experiment to confirm the skin barrier improvement effect

The experiment was conducted on 25 healthy women indoors at 25℃, 45% relative humidity, and no air flow.

Skin barrier damage was induced by using a 1% aqueous solution of sodium lauryl sulfate (SLS), which is known to deteriorate the skin barrier due to its strong toxicity as a surfactant, in Examples 1 to 5 and Comparative Examples 1 to 4 After applying the cosmetic composition to the upper arm of the arm, the amount of transdermal water loss (TEWL) was measured using TEWAMETER TM210 (C+K eletronic GmhH. Germany). That is, the skin barrier recovery rate was confirmed by measuring the TEWL value change according to the TEWL value over time (2, 4, 6, and 8 days). The experimental results are shown in Table 10 below.

As a result, it was found that the amount of percutaneous moisture loss was small when both the Platinum extract and Mantis plant extract were used. effect could be confirmed.

[Table 10]

[Experimental Example 3] Skin stability test

A human skin patch test was performed to check whether the cosmetic compositions including Examples 1 to 5 and Comparative Examples 1 to 4 were irritating to the skin. The test was conducted on 20 women in their 20s and 30s who have never had a skin irritation hypersensitivity reaction in their past history, and do not currently have skin diseases or skin allergies. First, the test site was wiped with 70% ethanol and dried. The prepared test material was dropped into the Finn chamber (100X10, EPITEST) and then sealed and applied to the back of the test subject. The patch was applied for 24 hours, and 1 hour and 24 hours after the patch was removed, the presence or absence of erythema and edema at the test site was observed using a magnifying glass (8MC-150, DAZOR).

The skin reaction was determined according to the regulations (Table 11) of the International Contact Dermatitis Research Group (ICDRG), and the average skin reactivity was calculated and expressed by Equation 1 below.

[Table 11]

[Equation 1]

Mean score = (score × number of responders)/(maximum score × total number of subjects) × 100

As a result, it was found that each of the Platinum extract and Mantis grass extract and its mixture was completely harmless to the skin (Table 12).

[Table 12]

Claims (5)

Platinum extract; And, a composition for moisturizing, comprising a mantis grass extract as an active ingredient. According to claim 1,
The platinum extract and mantis grass extract are,
When the platinum extract is 100 parts by weight, the mantis grass extract is included in 10 to 500 parts by weight, a moisturizing composition. According to claim 1,
The platinum extract and mantis grass extract are,
When the platinum extract is 100 parts by weight, the mantis grass extract is included in 50 to 350 parts by weight, a moisturizing composition. According to claim 1,
The platinum extract and mantis grass extract are,
Based on the total weight of the composition, which is included in an amount of 0.0001 to 10% by weight, a moisturizing composition. 5. The method according to any one of claims 1 to 4,
The composition is a cosmetic composition, moisturizing composition.