KR102212680B1 - Material for stabilization of cosmetic compositon comprising meadowfoam delta-lactone, and cosmetic composition comprising the same - Google Patents

Abstract

The present specification discloses a material for stabilizing a cosmetic composition containing Meadowfoam delta-lactone and a cosmetic composition comprising the same. The material as an aspect of the present invention maximizes the stability of the meadow foam delta-lactone-containing cosmetic, thereby minimizing precipitation or precipitation of components in the cosmetic composition. In addition, the cosmetic composition, which is an aspect of the present invention, is capable of stably delivering meadowdelta-lactone to the skin by impregnating meadowfoam delta-lactone in porous silica, thereby maximizing skin moisturizing effect, and at the same time, meadowfoam delta -Since lactone can absorb sebum through the leaked silica pores, it can effectively balance the moisture and oil of the skin.

Description

A material for stabilizing a cosmetic composition containing meadowfoam delta-lactone, and a cosmetic composition comprising the same

The present specification discloses a material for stabilizing a cosmetic composition containing Meadowfoam delta-lactone and a cosmetic composition comprising the same.

The skin is largely composed of three layers: epidermis, dermis, and subcutaneous fat. Among them, a stratum corneum is present in the epidermis located at the outermost part of the skin, which serves as a skin barrier that primarily protects the human body from external irritants. The skin barrier maintains homeostasis through various mechanisms such as skin moisturization, pH control, and antibacterial.

On the other hand, the skin barrier function may be disrupted due to physical and environmental factors. Due to the breakdown of the skin's barrier function, the skin becomes alkalized, and it changes into water-deficient skin in a chain. In addition, an imbalance between moisture and oil content occurs due to lack of moisture in the skin, resulting in excessive proliferation of skin flora, leading to skin diseases such as adult acne onset.

In order to improve this problem, it is necessary to maintain the oil and moisture balance by supplying moisture to the alkaline skin and removing excess sebum that has been excessively eluted. Accordingly, various moisturizing substances have been studied so far, but no substances that effectively moisturize and absorb sebum to alkalized skin have been found.

KR 10-2010-0087522 A

In one aspect, it is an object of the present invention to stably deliver meadowfoam delta-lactone to the skin.

In one aspect, it is an object of the present invention to effectively deliver moisture to alkalized skin such as lesioned skin.

In one aspect, an object of the present invention is to effectively remove sebum accumulated on the skin.

In one aspect, an object of the present invention is to improve the condition of moisture-deficient lipid/combination skin.

In one aspect, the object of the present invention is to fundamentally improve the skin barrier function.

In one aspect, an object of the present invention is to improve the stability of a cosmetic composition comprising meadow delta-lactone.

In one aspect, the present invention provides a cosmetic composition comprising a complex of silica and meadowfoam delta-lactone as an active ingredient.

The material as an aspect of the present invention maximizes the stability of the meadow foam delta-lactone-containing cosmetic, thereby minimizing precipitation or precipitation of components in the cosmetic composition. In addition, the cosmetic composition, which is an aspect of the present invention, is capable of stably delivering meadowdelta-lactone to the skin by impregnating meadowfoam delta-lactone in porous silica, thereby maximizing skin moisturizing effect, and at the same time, meadowfoam delta -Silica pores from which lactone has been leaked can absorb sebum, so it can effectively balance the moisture and oil of the skin.

1 is a diagram showing the operating principle of a complex of silica and meadowfoam delta-lactone according to the present invention.
Figure 2 is a diagram confirming the formulation stability of a lotion prepared using Meadowfoam delta-lactone.
3 is a diagram confirming the formulation stability of a lotion prepared using a complex of silica and meadowfoam delta-lactone.
4 is a diagram showing the skin moisturizing power of the lotion when a lotion prepared using a complex of silica and meadowfoam delta-lactone is applied to the skin.
5 is a diagram illustrating an effect of improving skin moisture loss when a lotion prepared using a complex of silica and meadowfoam delta-lactone is applied to the skin.
6 is a diagram illustrating the sebum adsorption effect of a lotion prepared using a complex of silica and meadowfoam delta-lactone.

Hereinafter, the present invention will be described in detail.

In one aspect, the present invention is a material for stabilizing a cosmetic composition, wherein the cosmetic composition includes meadowfoam delta-lactone, and the material includes a complex of silica and meadowfoam delta-lactone It is a material for stabilizing a cosmetic composition.

The stabilization may include chemical stability. For example, the stabilization may mean minimizing a phenomenon in which some of the components are precipitated or separated by a chemical action between components in the composition.

In the present specification, the complex may mean a material formed by physically or chemically gathering two or more materials. In one embodiment, the composite may further include a material other than the meadowfoam delta-lactone and silicon.

In one aspect, the silica may include porous silica.

In one aspect, the meadowfoam delta-lactone may include those impregnated with the silica. In one embodiment, the meadowfoam delta-lactone may include those impregnated in the pores of the silica.

Meadowfoam delta-lactone has an amphiphilic property, and when included in a cosmetic composition alone, there is a problem of deteriorating the stability of a cosmetic composition containing an emulsifier through interfacial collapse.

In addition, the meadowfoam delta-lactone may be included in an amount of 0.01 to 10% by weight based on the total weight of the composition. The meadowfoam delta-lactone may be included in preferably 0.01 to 7.0% by weight, more preferably 0.1 to 5.0% by weight.

In addition, in the above aspect, the silica may be included in an amount of 0.009 to 9.0% by weight, based on the total weight of the composition. The silica may preferably be contained in an amount of 0.09 to 6.3% by weight, more preferably 0.9 to 4.5% by weight.

When the silica is included in the above content range, the loading efficiency of meadowfoam delta-lactone is maximized.In particular, when it is included in less than 0.009% by weight, there may be a problem that an effective amount cannot be impregnated to impregnate the meadowform delta-lactone, If the content exceeds 9.0% by weight, the silica component may cause a problem of lowering the feeling of use of the cosmetic.

In one aspect, the present invention is a cosmetic composition comprising the complex as an active ingredient.

In one aspect, the cosmetic composition may be for skin moisturizing or sebum absorption.

In one aspect, the cosmetic composition, skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutrition lotion, massage cream, nutrition cream, moisture cream, hand cream, foundation, essence, nutrition essence, It may be any one or more selected from the group consisting of a pack, soap, cleansing foam, cleansing lotion, cleansing cream, body lotion, and body cleanser. In one embodiment, lotion formulations may be desirable.

In the composition, in addition to the essential ingredients described above in each formulation, other ingredients may be appropriately selected and blended by a person skilled in the art without difficulty depending on the type or purpose of use of other external preparations. For example, it may further include a sunscreen agent, a hair conditioning agent, fragrance, and the like.

The cosmetic composition may contain a cosmetically acceptable medium or base. These are all formulations suitable for topical application, for example solutions, gels, solid or paste anhydrous products, emulsions obtained by dispersing the oil phase in an aqueous phase, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) and/or It may be provided in the form of a nonionic vesicle dispersant, or in the form of a cream, skin, lotion, powder, ointment, spray or conceal stick. These compositions can be prepared according to conventional methods in the art.

When the formulation of the present invention is a solution or emulsion, a solvent, a solubilizing agent or an emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 ,3-butylglycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid ester of sorbitan.

When the formulation of the present invention is a suspension, liquid diluents such as water, ethanol or propylene glycol as carrier components, ethoxylated isostearyl alcohol, suspending agents such as polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, crystallites Sex cellulose, aluminum metahydroxide, bentonite, agar or tracant, and the like can be used.

When the formulation of the present invention is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracanth, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, or zinc oxide may be used as carrier components. I can.

When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder may be used as a carrier component. In particular, in the case of a spray, additionally chlorofluorohydrocarbon, propane / May contain propellants such as butane or dimethyl ether.

In one embodiment of the present invention, a thickener may be additionally included in the cosmetic composition. Thickeners included in the cosmetic composition of the present invention are methyl cellulose, carboxy methyl cellulose, carboxy methyl hydroxy guanine, hydroxy methyl cellulose, hydroxyethyl cellulose, carboxy vinyl polymer, polyquaternium, cetearyl alcohol, stearic acid, One or more selected from carrageenan and the like may be used.

In one embodiment, the composition may further include a stabilizer. Specifically, the stabilizer may include at least one selected from the group consisting of cholesterol, hydrogenated lecithin, glyceryl stearates, behayl alcohol, and cetearyl alcohol.

In one embodiment of the present invention, the cosmetic composition may contain a variety of suitable bases and additives as needed, and the types and amounts of these ingredients may be easily selected by the inventor. It may contain acceptable additives as needed, and for example, it may further include components such as preservatives, colors, flavors, and other additives conventional in the art.

Specifically, the preservative may be phenoxyethanol or 1,2-hexanediol, and the fragrance may be an artificial fragrance.

Hereinafter, the present invention will be described in more detail through examples. These examples are for illustrative purposes only, and it will be apparent to those of ordinary skill in the art that the scope of the present invention is not construed as being limited by these examples.

[Production Example] Preparation of composite

After heating the mesoporous porous silky car to an appropriate amount of mesoporous and liquefied by heating at 30 ~ 50 ℃, then gradually stirred at 50 ~ 3000 rpm using a stirrer to impregnate the silica with the meadow foam delta-lactone To prepare a composite. The content ratio of silica and meadow delta-lactone in the prepared composite was about 9:1.

[Experimental Example]

[Experimental Example 1]

[Experimental Example 1-1] Meadowform Delta-Lactone Stability Evaluation

Meadowfoam delta-lactone was not stabilized on silica, but was directly added to the lotion formulation, and the stability of the lotion was measured.

Stability was measured by the instability index, and instability (creaming or sedimentation) was confirmed by measuring the transmittance. Specifically, an accelerated stability test was performed using LUMiSizer (L.U.M. GmbH, Berlin, Germany), and the sample was accelerated at 4,000 rpm at 40°C and measured at 865 nm wavelength for 12 hours at 60 second intervals.

The instability index value is expressed as a value of 0 to 1, and a value closer to 0 means that there is no change in the transmittance of the composition and the composition is stable, and a value closer to 1 means that the stability of the composition decreases.

When meadow delta-lactone is not stabilized with silica and is directly administered to the composition, the instability index becomes 0.6 when administered at 0.01%, and the instability index becomes 0.95 when administered at 0.05%, and the meadow delta-lactone is administered directly to the composition. When doing so, it was confirmed that the stability of the cosmetic composition was greatly reduced (FIG. 2).

On the other hand, when silica and meadowfoam delta-lactone are added to each lotion without stabilizing meadowfoam delta-lactone, even when the concentration of added meadowfoam delta-lactone is very low (about 0.001%), the above Similarly, it was confirmed that the stability of the lotion was lowered.

[Experimental Example 1-2] Stability Evaluation of Meadowfoam Delta-Lactone Stabilized on Silica

The instability index was measured in the same manner as in Experimental Example 1-1 using the meadowfoam delta-lactone stabilized on silica prepared by the method of Preparation Example 1.

As a result, when the complex of silica and meadow delta-lactone containing 10% by weight of the total weight of the composition was administered to the lotion, the instability index was 0.35, and the meadowfoam delta-lactone was not stabilized. It was possible to confirm the stability of the composition significantly improved compared to.

In addition, when the meadow delta-lactone was included in 15% by weight, the instability index was measured as 0.64, and when it was included in 20%, the instability index was confirmed to deteriorate to 0.8 (FIG. 3).

In conclusion, it was confirmed that when the meadowfoam delta-lactone is stabilized in silica and administered to the cosmetic composition, the stability of the cosmetic composition including the meadowfoam delta-lactone can be improved.

[Experimental Example 2] Measurement of the moisturizing effect of a composite obtained by stabilizing meadowfoam delta-lactone in silica

[Experimental Example 2-1] Measurement of skin moisture retention

In order to find out the effect of the complex with Meadowfoam delta-lactone stabilized on silica on the skin moisturizing, the lotion of the general O/W formulation was set as a control, and Meadowfoam Delta-lactone was stabilized on silica in the lotion used as a control. 5.0% by weight of the composite was added (test group), and the moisturizing effect was measured.

Moisturizing effect was measured using a Corneometer to measure the amount of moisture in the skin, and 10 subjects were tested for 4 weeks.

As a result, it was confirmed that when a composite obtained by stabilizing Meadowfoam delta-lactone in silica was used, the moisture retention was improved by 24% or more compared to the case where it was not, thereby improving moisturizing effect (FIG. 4).

[Experimental Example 2-2] Confirmation of the effect of improving the skin barrier function of the complex obtained by stabilizing meadowfoam delta-lactone in silica

To find out the effect of the complex of Meadowfoam delta-lactone stabilized on silica on skin TEWL (Transepidermal water loss), a lotion of a general O/W formulation was used as a control, and Meadowfoam delta-lactone was used as a control lotion. 5.0% of the complex stabilized on silica was administered (test group), and skin moisture evaporation was measured using a Tewameter. The experiment was conducted with 10 subjects for 4 weeks. The higher the value, the greater the loss of moisture.

As a result, it was found that when the complex in which the meadowfoam delta-lactone was stabilized in silica was used, the amount of water evaporated in the skin was less than that in the case where it was not, and it was confirmed that there is an effect of strengthening the skin barrier function (Fig. ).

[Experimental Example 3] Confirmation of sebum adsorption effect of a composite obtained by stabilizing meadowfoam delta-lactone on silica

In order to confirm the effect on the skin sebum adsorption of the complex with Meadowfoam delta-lactone stabilized on silica, a lotion of a general O/W formulation was used as a control, and Meadowfoam delta-lactone was stabilized on silica in the lotion used as a control. 5.0% of the complex was administered (test group), and the amount of skin sebum reduction was measured using a sebum meter. The experiment was conducted with 10 subjects for 4 weeks. The higher the value, the greater the sebum adsorption amount.

As a result, it was confirmed that when a complex in which the meadowfoam delta-lactone was stabilized in silica was used, the sebum adsorption power (removal power) in the skin was excellent (Fig. 6).

Claims (6)

As a material for stabilizing cosmetic compositions,
The cosmetic composition includes meadowfoam delta-lactone,
The material includes a complex of silica and meadowfoam delta-lactone,
The cosmetic composition comprises a complex of silica and meadowfoam delta-lactone in an amount of 0.01 to 10% by weight based on the total weight of the composition,
The silica and meadowfoam delta-lactone are contained in a weight ratio of 9:1, a material for stabilization of a cosmetic composition. The method of claim 1,
The meadowfoam delta-lactone,
A material for stabilizing a cosmetic composition, including those impregnated with the silica. delete delete A cosmetic composition comprising the material of any one of claims 1 and 2. The cosmetic composition according to claim 5, wherein the cosmetic composition is for moisturizing skin or absorbing sebum.

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