KR102304645B1 - A shampoo composition for preventing hair loss using nanocapsule - Google Patents

Abstract

The present invention relates to a shampoo composition for preventing hair loss, and more particularly, to a shampoo composition for preventing hair loss comprising a shampoo base, jojoba oil, panthenol, peppermint, licorice extract, green tea extract, grapefruit seed extract and cinnamon extract capsule.
The present invention can provide a shampoo composition for preventing hair loss that is skin-friendly and non-irritating, can alleviate the progress of hair loss and promote hair growth.
In addition, the present invention provides a shampoo composition for preventing hair loss that can inhibit the growth of hair loss-causing bacteria and prevent excessive secretion of sebum because the nanocapsules penetrate into the pores of the scalp and the useful components of the nanocapsules can be efficiently absorbed into the scalp. can provide

Description

A shampoo composition for preventing hair loss using nanocapsules {A shampoo composition for preventing hair loss using nanocapsule}

The present invention relates to a shampoo composition for preventing hair loss, and more particularly, to a shampoo composition for preventing hair loss comprising a shampoo base, jojoba oil, panthenol, peppermint, licorice extract, green tea extract, grapefruit seed extract and cinnamon extract capsule.

Hair loss is known to be caused by an unbalanced diet, excessive drinking and smoking, drug use, lack of sleep, stress, childbirth, menopausal disorders, frequent perms and dyeing, and hormonal imbalance.

Androgenetic alopecia, which is caused by male hormones and heredity, usually begins in the 40s and 50s, but in severe cases, it starts right after puberty and may last for several decades. Hair loss mainly starts at the parietal region and gradually progresses to the entire head. In men, hair loss on both sides of the temporal region is predominant and hair loss is predominantly at the parietal region, and in women, the borders of facial scalp and hair are generally well preserved. It is rare for a complete bald patch to form.

As the hair loss proceeds due to these various causes, the number of hair loss increases as the hair on the crown and forehead begins to thin and lose strength, and if this phenomenon continues, the hair loss becomes severe enough to be observed directly with the naked eye.

As a treatment method for hair loss, there are topical application agents, oral medications, health supplements, gene transplantation surgery, hair transplantation surgery, etc., but these methods have a limited scope of use and do not prevent continuous hair loss.

In addition, the effect of drug treatment is temporary, and there is a side effect of accelerating the production of the scalp or sebum.

In order to solve the above problems, it is necessary to develop a shampoo that not only prevents hair loss, but also generates new hair, makes fine hair thick, and has a normal hair cycle once the hair comes out.

Korean Patent Publication No. 10-2006-0010035

An object of the present invention is to provide a shampoo composition for preventing hair loss that is skin-friendly and non-irritating, and can alleviate the progress of hair loss and promote hair growth.

In addition, the present invention provides a shampoo composition for preventing hair loss that can inhibit the growth of hair loss-causing bacteria and prevent excessive secretion of sebum because the nanocapsules penetrate into the pores of the scalp and the useful components of the nanocapsules can be efficiently absorbed into the scalp. intended to provide

The present invention provides a shampoo composition for preventing hair loss comprising a shampoo base, jojoba oil, panthenol, peppermint, licorice extract, green tea extract, grapefruit seed extract and cinnamon extract capsule.

In one embodiment of the present invention, the shampoo composition comprises 1 to 5 parts by weight of jojoba oil, 1 to 5 parts by weight of panthenol, 0.1 to 2 parts by weight of peppermint, 0.2 to 3 parts by weight of licorice extract, based on 100 parts by weight of the shampoo base, 0.2 to 3 parts by weight of green tea extract, 0.3 to 5 parts by weight of grapefruit seed extract, and 1 to 5 parts by weight of cinnamon extract capsules.

In one embodiment of the present invention, the cinnamon extract capsule consists of a core containing the cinnamon extract and a shell surrounding the core, wherein the shell comprises an emulsifier.

In one embodiment of the present invention, the emulsifier is a mixture of a fatty acid ester of sorbitan and a fatty acid ester of polyoxyethylene sorbitan.

The present invention also provides a shampoo for preventing hair loss comprising the shampoo composition for preventing hair loss.

The present invention can provide a shampoo composition for preventing hair loss that is skin-friendly and non-irritating, and can alleviate the progress of hair loss and promote hair growth.

In addition, the present invention provides a shampoo composition for preventing hair loss that can inhibit the growth of hair loss-causing bacteria and prevent excessive secretion of sebum because the nanocapsules penetrate into the pores of the scalp and the useful components of the nanocapsules can be efficiently absorbed into the scalp. can provide

Hereinafter, the shampoo composition for preventing hair loss of the present invention will be described in detail, but unless otherwise defined in technical terms and scientific terms used at this time, those of ordinary skill in the art to which this invention pertains have a meaning commonly understood, In the following description, descriptions of well-known functions and configurations that may unnecessarily obscure the gist of the present invention will be omitted.

The present invention relates to a shampoo composition for preventing hair loss comprising a shampoo base, jojoba oil, panthenol, peppermint, licorice extract, green tea extract, grapefruit seed extract and cinnamon extract capsule.

The shampoo composition is based on 100 parts by weight of the shampoo base, jojoba oil 1-5 parts by weight, panthenol 1-5 parts by weight, peppermint 0.1-2 parts by weight, licorice extract 0.2-3 parts by weight, green tea extract 0.2-3 parts by weight, grapefruit It may contain 0.3 to 5 parts by weight of the seed extract and 1 to 5 parts by weight of the cinnamon extract capsule.

The shampoo base is a mixture of basic materials used to prepare a shampoo, and refers to a composition including a surfactant. Any shampoo base may be used as long as it is a shampoo base commonly used in the art. For example, it may contain only 10 to 20% by weight of the surfactant and the remaining amount of purified water, and in addition to the surfactant and purified water, glycerin, betaine, propylene glycol, and the like may be included in the range of 0.5 to 3% by weight, respectively.

The jojoba oil is a vegetable oil, and it can easily penetrate into the skin in combination with other ingredients in the composition, thus facilitating the absorption of active ingredients, giving elasticity and luster to the skin, and making the skin texture soft and supple. have.

The content of the jojoba oil is preferably 1 to 5 parts by weight based on 100 parts by weight of the shampoo base, and when the content is less than 1 part by weight, wettability and elasticity are reduced, and when the content exceeds 5 parts by weight, the hair loss prevention properties are reduced.

The panthenol is used to improve moisturizing power, conditioning properties and skin elasticity.

The content of the panthenol is preferably 1 to 5 parts by weight based on 100 parts by weight of the shampoo base. When the content is less than 1 part by weight, the moisturizing power is reduced, and when it exceeds 5 parts by weight, the hair loss prevention properties are reduced.

The peppermint emits a unique scent, and is used to impart antibacterial properties and improve skin.

The content of peppermint is preferably 0.1 to 2 parts by weight based on 100 parts by weight of the shampoo base. If the content is less than 0.1 parts by weight, the fragrance is reduced, and when it exceeds 2 parts by weight, the hair loss prevention properties are reduced.

The licorice extract, green tea extract and grapefruit seed extract are used to improve the storage stability, moisturizing power and anti-hair loss properties of the composition.

The licorice extract may be prepared by heating and extracting licorice with a solvent such as water or ethanol, filtering the extract, and then concentrating under reduced pressure.

In addition, green tea extract and grapefruit seed extract may be prepared in the same manner as in the preparation method of the licorice extract.

The content of the licorice extract is preferably 0.2 to 3 parts by weight based on 100 parts by weight of the shampoo base, and when the content is less than 0.2 parts by weight, the storage stability is reduced, and when it exceeds 3 parts by weight, the hair loss prevention properties are reduced.

The content of the green tea extract is preferably 0.2 to 3 parts by weight based on 100 parts by weight of the shampoo base, and when the content is less than 0.2 parts by weight, the storage stability is reduced, and when it exceeds 3 parts by weight, the hair loss prevention properties are reduced.

The content of the grapefruit seed extract is preferably 0.3 to 5 parts by weight based on 100 parts by weight of the shampoo base, and when the content is less than 0.3 parts by weight, the storage stability is reduced, and when it exceeds 5 parts by weight, the hair loss prevention properties are lowered.

The cinnamon extract capsule is prepared as a nanocapsule of cinnamon extract, and the nanocapsule easily penetrates into the pores of the scalp so that the useful components of the nanocapsule can be efficiently absorbed into the scalp, thereby inhibiting the growth of hair loss-causing bacteria and sebum can prevent excessive secretion of

The content of the cinnamon extract capsules is preferably 1 to 5 parts by weight based on 100 parts by weight of the shampoo base, and when the content is less than 1 part by weight, the anti-hair loss property is lowered, and when the content exceeds 5 parts by weight, the dispersibility is lowered.

The cinnamon extract capsule consists of a core containing the cinnamon extract and a shell surrounding the core, and the shell may include an emulsifier.

The emulsifier may be a mixture of a fatty acid ester of sorbitan and a fatty acid ester of polyoxyethylene sorbitan.

The cinnamon extract nanocapsules can be prepared by adjusting the homogenization of the specific emulsifier and the cinnamon extract to prepare a capsule having a nano-sized particle size. The cinnamon extract is stably dispersed by controlling the difference in affinity between the cinnamon extract and the emulsifier and the affinity between the cinnamon extract and water on the surface of the cinnamon extract, and inducing the electrostatic repulsion between the emulsifier polymer materials surrounding the cinnamon extract is encapsulated.

The nanocapsules are prepared by mixing distilled water and cinnamon extract to prepare a cinnamon extract solution; Preparing an emulsifier solution by mixing distilled water and an emulsifier; preparing a mixed solution by mixing the cinnamon extract solution and the emulsifier solution; and homogenizing the mixed solution.

More specifically, the mixed solution includes a cinnamon extract solution obtained by mixing powdered cinnamon extract in distilled water, and an emulsifying agent solution obtained by mixing an emulsifier in distilled water. At this time, the cinnamon extract solution and the emulsifier solution are prepared separately from each other, and it is preferable to mix them while performing a homogenization process. This is preferable because it promotes encapsulation and can produce uniform nanocapsules.

The emulsifier facilitates dispersion through the encapsulation process, and allows the surface of the cinnamon extract to be wrapped by using a high affinity with the cinnamon extract compared to the affinity between the cinnamon extract and water in the aqueous phase.

That is, in the encapsulation process according to the present invention, the affinity between the cinnamon extract and the polymer is adjusted to be higher than that of the cinnamon extract and water so that the emulsifier polymer is well adsorbed on the surface layer of the cinnamon extract. At this time, the emulsifier polymer is formed as an adsorption layer surrounding the cinnamon extract, so that the nanocapsules can be stabilized by the electrostatic repulsion of individual particles.

The emulsifier is preferably a mixture of a fatty acid ester of sorbitan and a fatty acid ester of polyoxyethylene sorbitan.

The fatty acid ester of sorbitan is sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan monooleate, etc., and the fatty acid ester of polyoxyethylene sorbitan is polyoxyethylene sorbitan monolaurate, Polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, and the like can be used without limitation.

As a specific example, the fatty acid ester of sorbitan may include span 80, and the fatty acid ester of polyoxyethylene sorbitan may include polysorbate 80.

The emulsifier may be used in an amount of 1 to 10% by weight, preferably 2 to 8% by weight, based on the total weight of the mixed solution. If it is out of the above range, the desired encapsulation may not be performed smoothly and dispersibility and uniformity may be deteriorated.

In addition, the weight ratio of the fatty acid ester of sorbitan and the fatty acid ester of polyoxyethylene sorbitan is preferably 10 to 30:70 to 90. When the above range is satisfied, the dispersibility of the nanocapsules is excellent.

The cinnamon extract in the mixed solution may be contained in an amount of preferably 60 to 90% by weight, more preferably 65 to 85% by weight. When the above range is satisfied, dispersibility and uniformity are excellent.

The weight ratio of the emulsifier and the cinnamon extract is preferably 1:8 to 1:20, more preferably 1:9 to 1:15. That is, the cinnamon extract and the emulsifier are better by increasing the dispersibility through the weight mixing ratio at the same time as each content and enabling more stable nanoencapsulation.

In addition, the present invention may further include a lycopene extract capsule, the lycopene extract contains a carotenoid as an useful ingredient.

The content of the lycopene extract capsules is preferably 1 to 5 parts by weight based on 100 parts by weight of the shampoo base. If the content is less than 1 part by weight, the anti-hair loss property is lowered, and when the content exceeds 5 parts by weight, the dispersibility is lowered.

The lycopene extract capsule may be prepared in the same way as the manufacturing method of the cinnamon extract capsule.

In addition, the present invention may further include a cinnamon extract, and the content of the cinnamon extract is preferably 0.2 to 3 parts by weight based on 100 parts by weight of the shampoo base.

At this time, when the cinnamon extract capsule and the cinnamon extract are used at the same time, the weight ratio of the cinnamon extract capsule and the cinnamon extract is preferably 70-90:10-30, and when the weight ratio satisfies the above numerical range, the hair loss prevention properties can be maximized. have.

In addition, the present invention relates to a shampoo for preventing hair loss comprising the shampoo composition for preventing hair loss.

The shampoo is skin-friendly and non-irritating, and can alleviate the progress of hair loss and promote hair growth.

In addition, as the nanocapsules of the present invention penetrate into the pores of the scalp, useful components of the nanocapsules can be efficiently absorbed into the scalp, thereby inhibiting the growth of hair loss-causing bacteria and preventing excessive secretion of sebum.

Hereinafter, the present invention will be described in detail with reference to specific examples, but the scope of the present invention is not limited by these examples.

(Example 1)

A mixed solution was prepared by mixing an emulsifier solution in which 6.4 g of polyoxyethylene sorbitan monooleate and 1.6 g of sorbitan monooleate were mixed with 3 g of distilled water, and a cinnamon extract solution in which 12 g of distilled water was added to 80 g of cinnamon extract. The mixed solution was ball milled.

At this time, the ball mill treatment was carried out at 25° C. for 30 minutes at 300 rpm after putting 116 g of 0.3 mm beads and 9 g of the mixed solution into a 60 ml plastic bottle, and then adding 16 g of distilled water to prepare cinnamon extract nanocapsules (particle diameter 128 nm).

Shampoo using 100 parts by weight of shampoo base, 2 parts by weight of jojoba oil, 2 parts by weight of panthenol, 0.5 parts by weight of peppermint, 1 part by weight of licorice extract, 1 part by weight of green tea extract, 1 part by weight of grapefruit seed extract and 3 parts by weight of cinnamon extract capsule A composition was prepared.

(Example 2)

A shampoo composition was prepared in the same manner as in Example 1, except that 0.5 parts by weight of the cinnamon extract capsule was used.

(Example 3)

A shampoo composition was prepared in the same manner as in Example 1, except that 8 parts by weight of the cinnamon extract capsule was used.

(Example 4)

A shampoo composition was prepared in the same manner as in Example 1, except that 3 parts by weight of the lycopene extract capsule was additionally used.

(Example 5)

A shampoo composition was prepared in the same manner as in Example 1, except that 0.8 parts by weight of the cinnamon extract was additionally used.

(Comparative Example 1)

A shampoo composition was prepared in the same manner as in Example 1, except that the cinnamon extract capsule was not used.

(Comparative Example 2)

A shampoo composition was prepared in the same manner as in Example 1, except that cinnamon extract was used instead of the cinnamon extract capsule.

(sensory test)

A shampoo was prepared from the composition of the present invention, tested for 50 subjects for 16 weeks, and then visual evaluation, hair richness, number of hairs falling out, improvement of bangs, etc. were performed.

Each subject shampooed once a day, and the visual evaluation, hair abundance, number of hair loss, and improvement of bangs were measured on a 5-point scale (5: very good, 4: excellent, 3: average, 2: bad, 1). : very bad), and after examining the above characteristics, it was arithmetic averaged.

Visual evaluation fullness of hair number of hairs falling out improvement of bangs Example 1 3.8 3.9 3.7 3.9 Example 2 3.2 3.1 3.2 3.1 Example 3 3.1 3.3 3.2 3.2 Example 4 4.2 3.9 4.2 4.2 Example 5 4.5 4.5 4.5 4.6 Comparative Example 1 2.5 2.5 2.6 2.5 Comparative Example 2 2.6 2.7 2.5 2.6

As can be seen from Table 1, Examples 1 to 5 are excellent in visual evaluation, hair richness, number of hairs falling out, and improvement of bangs. In particular, Examples 1, 4 and 5 have the best properties.

On the other hand, it can be seen that Comparative Examples 1 and 2 are inferior in the above properties to those of Examples.

(Measure the thickness of hair)

After immersing the hair in the prepared shampoo for 20 minutes, the thickness of the hair was measured. In this case, the thickness of the hair was measured using a hair thickness meter (ID-C112BS), and the rate of increase in the thickness of the hair before and after immersion in shampoo was calculated.

Increase in hair thickness (%) Example 1 2.7 Example 2 2.2 Example 3 2.1 Example 4 3.2 Example 5 3.5 Comparative Example 1 0.3 Comparative Example 2 0.6

As can be seen from Table 2, it can be seen that Examples 1 to 5 increase the hair thickness, and in particular, Examples 1, 4 and 5 have the best properties.

On the other hand, it can be seen that Comparative Examples 1 and 2 are inferior in the above properties to those of Examples.

Claims (5)

In the shampoo composition for preventing hair loss comprising a shampoo base, jojoba oil, panthenol, peppermint, licorice extract, green tea extract, grapefruit seed extract, cinnamon extract capsule and cinnamon extract,
The shampoo composition contains 1 to 5 parts by weight of jojoba oil, 1 to 5 parts by weight of panthenol, 0.1 to 2 parts by weight of peppermint, 0.2 to 3 parts by weight of licorice extract, 0.2 to 3 parts by weight of green tea extract, grapefruit based on 100 parts by weight of the shampoo base. 0.3 to 5 parts by weight of seed extract, 1 to 5 parts by weight of cinnamon extract capsule, and 0.2 to 3 parts by weight of cinnamon extract,
The weight ratio of the cinnamon extract capsule and the cinnamon extract is 70-90:10-30,
The cinnamon extract capsule consists of a core containing cinnamon extract and an emulsifier surrounding the core,
Shampoo composition for preventing hair loss, characterized in that the weight ratio of the emulsifier and the cinnamon extract constituting the cinnamon extract capsule is 1:8 to 1:20.
delete delete According to claim 1,
The emulsifier is a shampoo composition for preventing hair loss, characterized in that it is a mixture of a fatty acid ester of sorbitan and a fatty acid ester of polyoxyethylene sorbitan.
A shampoo for preventing hair loss comprising the shampoo composition for preventing hair loss of claim 1.