KR20240106523A - A multi-functional microcapsule shampoo additives - Google Patents

Abstract

The present invention relates to a multifunctional microcapsule shampoo additive, and more specifically, the steps of preparing a core solution by mixing distilled water, a core material, and a surfactant; Preparing a shell solution by mixing distilled water and a polymer; and mixing the core solution and the shell solution to produce microcapsules. The present invention relates to a method for producing microcapsules including a method, microcapsules, and anti-hair loss shampoos produced therefrom.

Description

{A multi-functional microcapsule shampoo additives}

The present invention relates to a multifunctional microcapsule shampoo additive, and more specifically, the steps of preparing a core solution by mixing distilled water, a core material, and a surfactant; Preparing a shell solution by mixing distilled water and a polymer; and mixing the core solution and the shell solution to produce microcapsules. The present invention relates to a method for producing microcapsules including a method, microcapsules, and anti-hair loss shampoos produced therefrom.

Hair loss is known to be caused by unbalanced diet, excessive drinking and smoking, drug use, lack of sleep, stress, childbirth, menopausal disorders, frequent perms and dyeing, and hormonal imbalance.

Androgenetic alopecia, which is caused by male hormones and genetics, generally begins in the 40s and 50s, but in severe cases, it begins immediately after puberty and can last for decades. Hair loss mainly starts in the parietal region and gradually progresses to the entire head. In men, recession of the hairline on both sides of the head and hair loss predominates in the parietal region, and in women, the border of facial scalp hair is generally well preserved. It is rare for a complete bald spot to form.

Hair loss that occurs due to these various causes increases in number as the hair on the crown and forehead begins to become thinner and weaker. If this phenomenon continues, hair loss becomes severe enough to be directly observed with the naked eye.

Treatment methods for hair loss include topical application, oral medication, health supplements, gene transplant surgery, and hair transplant surgery, but these methods have a limited range of use and do not provide continuous hair loss prevention.

Additionally, the effects of drug treatment are temporary and have the side effect of accelerating the production of scalp or sebum.

In order to solve the above problems, it is necessary to develop a shampoo that not only prevents hair loss, but also generates new hair, makes fine hair thicker, and allows the hair to have a normal hair cycle once it has grown.

Korean Patent Publication No. 10-2006-0010035

The purpose of the present invention is to provide microcapsules for preventing hair loss that are friendly to the skin, are not irritating, and can alleviate the progression of hair loss and promote hair growth.

In addition, the present invention allows microcapsules to penetrate into the pores of the scalp and the useful ingredients of the microcapsules can be efficiently absorbed into the scalp, thereby suppressing the growth of hair loss-causing bacteria, reducing heat sensation in the scalp, and preventing excessive secretion of sebum. The purpose is to provide shampoo for preventing hair loss.

The present invention includes the steps of preparing a core solution by mixing distilled water, a core material, and a surfactant;

Preparing a shell solution by mixing distilled water and a polymer; and

It provides a method for manufacturing microcapsules including: manufacturing microcapsules by mixing the core solution and the shell solution.

In one embodiment of the present invention, the core solution is characterized in that it contains 5 to 30 parts by weight of the core material and 5 to 30 parts by weight of the surfactant based on 100 parts by weight of distilled water.

In one embodiment of the present invention, the core material is characterized in that one or more of menthol and cinnamon oil are used.

In one embodiment of the present invention, the polymer is characterized in that one or more of melamine-formaldehyde and lecithin are used.

The present invention also provides microcapsules prepared from the above production method.

In addition, the present invention provides a shampoo for preventing hair loss containing the microcapsules.

The present invention can provide microcapsules for preventing hair loss that are friendly to the skin, are not irritating, and can alleviate the progression of hair loss and promote hair growth.

In addition, the present invention allows microcapsules to penetrate into the pores of the scalp and the useful ingredients of the microcapsules can be efficiently absorbed into the scalp, thereby suppressing the growth of hair loss-causing bacteria, reducing heat sensation in the scalp, and preventing excessive secretion of sebum. Shampoo for preventing hair loss can be provided.

Figure 1 shows the OM image and DLS analysis results of the microcapsule (No. 1) of the present invention.
Figure 2 shows the OM image and DLS analysis results of the microcapsule (No. 2) of the present invention.
Figure 3 shows the OM image and DLS analysis results of the microcapsule (No. 3) of the present invention.
Figure 4 shows the TGA results of the microcapsule (No. 3) of the present invention.
Figure 5 shows an SEM image of the microcapsule (No. 3) of the present invention.
Figure 6 shows the manufacturing conditions for the shampoo of the present invention.
Figure 7 shows the results of thermal change in the scalp analyzed with an IR camera (FLUKE TiS20+ Thermal Imager) after washing the scalp using a regular shampoo and a functional shampoo made with microcapsules (No. 3) of the present invention.
Figure 8 shows an OM image of the microcapsule (No. 4) of the present invention.
Figure 9 shows an SEM image of the microcapsule (No. 4) of the present invention.
Figure 10 shows the results of thermal change in the scalp analyzed with an IR camera (FLUKE TiS20+ Thermal Imager) after washing the scalp using a regular shampoo and a functional shampoo made with microcapsules (No. 4) of the present invention.

Hereinafter, the shampoo composition for preventing hair loss of the present invention will be described in detail. However, if there is no other definition in the technical and scientific terms used herein, they have the meaning commonly understood by those skilled in the art to which this invention pertains, In the following description, descriptions of known functions and configurations that may unnecessarily obscure the gist of the present invention are omitted.

The present invention includes the steps of preparing a core solution by mixing distilled water, a core material, and a surfactant;

Preparing a shell solution by mixing distilled water and a polymer; and

It relates to a method of manufacturing microcapsules comprising: manufacturing microcapsules by mixing the core solution and the shell solution.

In the step of preparing the core solution, the core solution can be prepared by mixing distilled water, a core material, and a surfactant.

The core solution may include 5 to 30 parts by weight of core material and 5 to 30 parts by weight of surfactant based on 100 parts by weight of distilled water. When the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized. .

The core material may be one or more from menthol, dexpanthenol, salicylic acid, niacinamide, biotin, zinc pyrithione, cinnamon oil and essential oils.

The essential oil may include lavender, rose, rosemary, basil, cypress, cinnamon, eucalyptus, jasmine, chamomile, peppermint, cinnamon, clove, thyme, oregano, etc.

The core material can be used by dissolving one or more selected from menthol, dexpanthenol, salicylic acid, niacinamide, biotin, and zinc pyrithione in cinnamon oil.

Additionally, the core material can be used by dissolving at least one selected from menthol, dexpanthenol, salicylic acid, niacinamide, biotin, and zinc pyrithione in cinnamon oil and essential oil.

In addition, the present invention can be used as a core material by mixing menthol and cinnamon oil, and in this case, the weight ratio of the menthol and cinnamon oil is preferably 20 to 40:60 to 80.

When the weight ratio satisfies the above numerical range, dispersibility and hair loss prevention properties can be maximized.

In addition, the present invention can be used as a core material by mixing menthol and essential oil. In this case, the weight ratio of menthol and essential oil is preferably 20 to 40:60 to 80.

In addition, the present invention can be used as a core material by mixing menthol, cinnamon oil, and essential oil. In this case, the weight ratio of menthol, cinnamon oil, and essential oil is preferably 30 to 50:100:10 to 30.

In addition, the present invention can be used as a core material by mixing menthol, dexpanthenol, and cinnamon oil. In this case, the weight ratio of menthol, dexpanthenol, and cinnamon oil is preferably 20 to 40:5 to 20:100.

The surfactant is a fatty acid ester of polyoxyethylene sorbitan such as polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, and polyoxyethylene sorbitan monooleate. It can be used without restrictions.

Additionally, the core solution may additionally contain ethyl acetate to improve dispersibility.

The content of ethyl acetate is preferably 10 to 35 parts by weight based on 100 parts by weight of distilled water, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

In addition, the core solution may additionally contain polyols such as glycerin, polyethylene glycol, polypropylene glycol, dipropylene glycol, propylene glycol, butylene glycol, propanediol, ethylhexanediol, and pentylene glycol to improve dispersibility. there is.

The content of polyol is preferably 1 to 10 parts by weight based on 100 parts by weight of distilled water, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

In addition, the present invention can be used as a polyol mixed with glycerin and dipropylene glycol, and in this case, the weight ratio of glycerin and dipropylene glycol is preferably 60 to 80:20 to 40.

In addition, the present invention can be used as a polyol by mixing glycerin, dipropylene glycol, and propylene glycol. In this case, the weight ratio of glycerin, dipropylene glycol, and propylene glycol is preferably 100:20 to 50:5 to 20.

In the step of preparing the shell solution, the shell solution can be prepared by mixing distilled water and polymer.

The shell solution may contain 60 to 140 parts by weight of polymer based on 100 parts by weight of distilled water, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

The polymer may be one or more from melamine-formaldehyde and lecithin.

In addition, the present invention can be used as a polymer by mixing melamine-formaldehyde and lecithin. In this case, the weight ratio of melamine-formaldehyde and lecithin is preferably 20 to 40:60 to 80.

When the weight ratio satisfies the above numerical range, dispersibility and hair loss prevention properties can be maximized.

Additionally, the shell solution may additionally contain ethyl acetate to improve dispersibility.

The content of ethyl acetate is preferably 10 to 35 parts by weight based on 100 parts by weight of distilled water, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

In addition, the shell solution may additionally contain polyols such as glycerin, polyethylene glycol, polypropylene glycol, dipropylene glycol, propylene glycol, butylene glycol, propanediol, ethylhexanediol, and pentylene glycol to improve dispersibility. there is.

The content of polyol is preferably 1 to 10 parts by weight based on 100 parts by weight of distilled water, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

In addition, the present invention can be used as a polyol mixed with glycerin and dipropylene glycol, and in this case, the weight ratio of glycerin and dipropylene glycol is preferably 60 to 80:20 to 40.

In addition, the present invention can be used as a polyol by mixing glycerin, dipropylene glycol, and propylene glycol. In this case, the weight ratio of glycerin, dipropylene glycol, and propylene glycol is preferably 100:20 to 50:5 to 20.

In the step of manufacturing the microcapsule, the microcapsule may be produced by mixing the core solution and the shell solution.

The step may include 10 to 40 parts by weight of the shell solution based on 100 parts by weight of the core solution, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

Additionally, this step may additionally include cellulose to prevent agglomeration of microcapsules.

The content of cellulose is preferably 2 to 10 parts by weight based on 100 parts by weight of the core solution, and when the content satisfies the above numerical range, dispersibility and anti-hair loss properties can be maximized.

The cellulose may be natural cellulose, crystalline cellulose, regenerated cellulose, etc. without limitation.

Additionally, the cellulose can be surface treated with an acid compound, and acid compounds used for the surface treatment include glycolic acid, lactic acid, tartaric acid, citric acid, malic acid, and salicylic acid.

The acid compound may react with the hydroxyl group of cellulose to modify the surface of cellulose.

At this time, the cellulose may be cellulose surface-treated with glycolic acid, lactic acid, tartaric acid, citric acid, or malic acid; It is preferable to use a mixture of cellulose surface-treated with salicylic acid.

Cellulose surface treated with glycolic acid, lactic acid, tartaric acid, citric acid or malic acid; and the weight ratio of cellulose surface-treated with salicylic acid is preferably 10 to 30:70 to 90.

The present invention also relates to microcapsules produced from the above production method.

The microcapsule consists of a core containing a core material and a shell surrounding the core, and the shell may contain a polymer.

In addition, the present invention relates to a shampoo for preventing hair loss containing the microcapsules.

The shampoo is friendly to the skin and is not irritating, and can alleviate the progression of hair loss and promote hair growth.

In addition, the microcapsules of the present invention penetrate into the pores of the scalp and the useful ingredients of the microcapsules can be efficiently absorbed into the scalp, thereby suppressing the growth of hair loss-causing bacteria, reducing heat sensation in the scalp, and preventing excessive secretion of sebum. .

The present invention will be described in detail below with reference to specific examples, but the scope of the present invention is not limited by these examples.

(Example 1)

A core solution was prepared by mixing 100 parts by weight of distilled water, 15 parts by weight of menthol, and 15 parts by weight of polyoxyethylene sorbitan monooleate.

A shell solution was prepared by mixing 100 parts by weight of distilled water and 100 parts by weight of melamine-formaldehyde.

Microcapsules (No. 1) were prepared by mixing 100 parts by weight of the core solution and 20 parts by weight of the shell solution.

Figure 1 shows the OM image and DLS analysis results of the microcapsule (No. 1).

In case of No. 1, the microcapsule was successfully formed, and it can be confirmed that the size of the microcapsule was 0.22㎛.

(Example 2)

A core solution was prepared by mixing 100 parts by weight of distilled water, 15 parts by weight of menthol, and 15 parts by weight of polyoxyethylene sorbitan monooleate.

A shell solution was prepared by mixing 100 parts by weight of distilled water and 100 parts by weight of lecithin.

Microcapsules (No. 2) were prepared by mixing 100 parts by weight of the core solution and 20 parts by weight of the shell solution.

Figure 2 shows the OM image and DLS analysis results of the microcapsule (No. 2).

In case of No. 2, the microcapsule was successfully formed, and the size of the microcapsule was confirmed to be 0.23㎛.

(Example 3)

A core solution was prepared by mixing 100 parts by weight of distilled water, 15 parts by weight of cinnamon oil, and 15 parts by weight of polyoxyethylene sorbitan monooleate.

A shell solution was prepared by mixing 100 parts by weight of distilled water and 100 parts by weight of lecithin.

Microcapsules (No. 3) were prepared by mixing 100 parts by weight of the core solution and 20 parts by weight of the shell solution.

Figure 3 shows the OM image and DLS analysis results of the microcapsule (No. 3).

In case of No. 3, the microcapsule was successfully formed, and the size of the microcapsule was confirmed to be 0.21㎛.

Figure 4 shows the TGA results of microcapsule (No. 3).

Around 100℃, the weight loss due to moisture is 39.9%, and at 110~200℃, there is a 19.61% weight loss, which appears to be a decrease in the weight of the shell, and the weight loss (24.2%) above 400℃ is a decrease in the weight of the core. It looks like

Figure 5 shows an SEM image of microcapsule (No. 3).

In the case of No. 3, it can be seen that the microcapsule has a spherical shape surrounding the core material.

Figure 6 shows the manufacturing conditions for the shampoo of the present invention.

Phase A is an oil phase, Phase B is an aqueous phase, Phase C is used to adjust pH, and Phase D represents a solution containing the microcapsules.

Figure 7 shows the results of thermal change in the scalp analyzed with an IR camera (FLUKE TiS20+ Thermal Imager) after washing the scalp using a regular shampoo and a functional shampoo made with microcapsules (No. 3) of the present invention.

When the functional shampoo of the present invention is used, a temperature drop of 5°C can be found compared to when a regular shampoo is used. This is because the scalp temperature was lowered due to the volatile nature of the core material, cinnamon oil. When the scalp temperature drops, pores shrink and hair loss can be prevented.

(Example 4)

A core solution was prepared by mixing 100 parts by weight of distilled water, 5 parts by weight of menthol, 10 parts by weight of cinnamon oil, and 15 parts by weight of polyoxyethylene sorbitan monooleate.

A shell solution was prepared by mixing 100 parts by weight of distilled water and 100 parts by weight of lecithin.

Microcapsules (No. 4) were prepared by mixing 100 parts by weight of the core solution and 20 parts by weight of the shell solution.

Figure 8 shows the OM image of microcapsule (No. 4).

In case of No. 4, it can be confirmed that microcapsules were successfully formed.

Figure 9 shows an SEM image of microcapsule (No. 4).

In the case of No. 4, it can be seen that the microcapsules were manufactured uniformly in a spherical shape.

Figure 10 shows the results of thermal change in the scalp analyzed with an IR camera (FLUKE TiS20+ Thermal Imager) after washing the scalp using a regular shampoo and a functional shampoo made with microcapsules (No. 4) of the present invention.

When the functional shampoo of the present invention is used, it can be found that the temperature drops by 4.2°C compared to when a regular shampoo is used. This is because the scalp temperature was lowered due to the volatile nature of the core substances, menthol and cinnamon oil. When the scalp temperature drops, pores shrink and hair loss can be prevented.

(Example 5)

Microcapsules were prepared in the same manner as in Example 3, except that a core solution was prepared by adding 20 parts by weight of ethyl acetate.

(Example 6)

Microcapsules were prepared in the same manner as in Example 3, except that 5 parts by weight of glycerin was added to prepare the core solution.

(Example 7)

Microcapsules were prepared in the same manner as in Example 3, except that instead of 100 parts by weight of lecithin, 70 parts by weight of lecithin and 30 parts by weight of melamine-formaldehyde were used to prepare the shell solution.

(Comparative Example 1)

A regular shampoo that did not contain microcapsules was used.

(Sensory test)

A shampoo containing the microcapsules of the present invention was prepared and tested on 10 subjects for 4 weeks, and then visual evaluation, hair abundance, number of fallen hairs, improvement of bangs line, etc. were performed.

Each subject shampooed once a day, and visual evaluation, hair abundance, number of fallen hairs, and improvement of frontal hairline were assessed using a 5-point scale (5: excellent, 4: excellent, 3: average, 2: bad, 1) : Very bad), and after examining the above characteristics, the arithmetic average was taken.

visual evaluation abundance of hair number of hairs shed Improvement of bangs line Example 3 3.6 3.5 3.6 3.6 Example 4 4.2 4.3 4.2 4.3 Example 5 4.3 4.3 4.2 4.2 Example 6 4.2 4.4 4.2 4.3 Example 7 4.5 4.5 4.5 4.6 Comparative Example 1 2.5 2.4 2.6 2.6

As can be seen in Table 1, Examples 3 to 7 are excellent in visual evaluation, hair abundance, number of hairs falling out, and improvement in bangs line. In particular, Examples 4 to 7 have the best properties.

On the other hand, it can be confirmed that the characteristics of Comparative Example 1 are inferior to those of the Example.

(Temperature change of scalp)

A shampoo containing the microcapsules of the present invention was prepared, the scalp was washed, and the temperature change of the scalp was measured using an IR camera (FLUKE TiS20+ Thermal Imager).

The degree of reduction in scalp temperature when using the shampoo of the present invention was calculated compared to the temperature of the scalp when using the general shampoo of Comparative Example 1.

Decrease in scalp temperature (℃) Example 3 5.0 Example 4 4.2 Example 5 5.4 Example 6 5.5 Example 7 5.5 Comparative Example 1 -

As can be seen in Table 2, it can be seen that the temperature of the scalp decreases when using a shampoo containing microcapsules in Examples 3 to 7.

Claims (8)

Preparing a core solution by mixing distilled water, a core material, and a surfactant;
Preparing a shell solution by mixing distilled water and a polymer; and
Manufacturing a microcapsule comprising: mixing the core solution and the shell solution to produce a microcapsule.
According to paragraph 1,
The core solution is a method of producing microcapsules, characterized in that it contains 5 to 30 parts by weight of core material and 5 to 30 parts by weight of surfactant based on 100 parts by weight of distilled water.
According to paragraph 2,
A method for producing microcapsules, characterized in that the core material is used by dissolving menthol in cinnamon oil.
According to paragraph 2,
A method for producing microcapsules, characterized in that the core material is used by dissolving one or more selected from dexpanthenol, salicylic acid, niacinamide, biotin, and zinc pyrithione in cinnamon oil.
According to paragraph 2,
A method for producing microcapsules, characterized in that the core material is one or more selected from menthol, dexpanthenol, salicylic acid, niacinamide, biotin and zinc pyrithione, dissolved in cinnamon oil and essential oil.
According to paragraph 3,
A method for producing microcapsules, characterized in that the polymer is used at least one from melamine-formaldehyde and lecithin.
A microcapsule manufactured from the manufacturing method of any one of claims 1 to 6.
A shampoo for preventing hair loss containing the microcapsules of claim 7.