KR102207507B1 - 내시경 진단용 염료를 함유하는 고체 경구용 조성물 - Google Patents

내시경 진단용 염료를 함유하는 고체 경구용 조성물 Download PDF

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Publication number
KR102207507B1
KR102207507B1 KR1020157010942A KR20157010942A KR102207507B1 KR 102207507 B1 KR102207507 B1 KR 102207507B1 KR 1020157010942 A KR1020157010942 A KR 1020157010942A KR 20157010942 A KR20157010942 A KR 20157010942A KR 102207507 B1 KR102207507 B1 KR 102207507B1
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dye
liter
solid composition
solid
intestinal
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Korean (ko)
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KR20150068412A (ko
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루이기 모로
알레산드로 레피시
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코스모 테크놀러지스 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/003—Thiazine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0084—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion liposome, i.e. bilayered vesicular structure
    • A61K49/0086—Polymersome, i.e. liposome with polymerisable or polymerized bilayered-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020157010942A 2012-10-19 2013-09-26 내시경 진단용 염료를 함유하는 고체 경구용 조성물 Active KR102207507B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261715981P 2012-10-19 2012-10-19
EP12189206.1 2012-10-19
EP12189206.1A EP2722058A1 (en) 2012-10-19 2012-10-19 Solid oral composition containing dyes for use in endoscopic diagnosis
US61/715,981 2012-10-19
PCT/EP2013/070060 WO2014060199A1 (en) 2012-10-19 2013-09-26 Solid oral composition containing dyes for use in endoscopic diagnosis

Publications (2)

Publication Number Publication Date
KR20150068412A KR20150068412A (ko) 2015-06-19
KR102207507B1 true KR102207507B1 (ko) 2021-01-27

Family

ID=47137560

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157010942A Active KR102207507B1 (ko) 2012-10-19 2013-09-26 내시경 진단용 염료를 함유하는 고체 경구용 조성물

Country Status (27)

Country Link
US (4) US20150283268A1 (https=)
EP (3) EP2722058A1 (https=)
JP (1) JP6267210B2 (https=)
KR (1) KR102207507B1 (https=)
CN (3) CN117462704A (https=)
AR (1) AR091984A1 (https=)
AU (1) AU2013331964B2 (https=)
BR (1) BR112015008772A2 (https=)
CA (1) CA2886201C (https=)
DK (2) DK2908866T3 (https=)
ES (2) ES2721916T3 (https=)
FI (1) FI3650048T3 (https=)
HR (1) HRP20190710T1 (https=)
HU (1) HUE043112T2 (https=)
IL (1) IL237907A (https=)
IN (1) IN2015DN02818A (https=)
LT (1) LT2908866T (https=)
MX (1) MX361737B (https=)
NZ (1) NZ706363A (https=)
PL (1) PL2908866T3 (https=)
PT (1) PT2908866T (https=)
RS (1) RS59152B1 (https=)
RU (1) RU2649783C2 (https=)
TR (1) TR201905800T4 (https=)
TW (1) TWI651102B (https=)
WO (1) WO2014060199A1 (https=)
ZA (1) ZA201502370B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3544638A1 (en) * 2016-11-28 2019-10-02 Cosmo Technologies Ltd. Solid oral composition containing dyes
IT201900003113A1 (it) * 2019-03-04 2020-09-04 Azienda Ospedaliero Univ Policlinico S Orsola Malpighi Bologna Bevanda coadiuvante

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070077202A1 (en) 2005-06-12 2007-04-05 Pentax Corporation Histostain composition for endoscope
WO2011107945A1 (en) * 2010-03-04 2011-09-09 Cosmo Technologies Ltd. Solid composition for the oral administration of dyes and diagnostic use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2129273C1 (ru) * 1997-11-26 1999-04-20 Московский научно-исследовательский онкологический институт им.П.А.Герцена Способ эндоскопической флюоресцентной диагностики злокачественных опухолей полых органов
EP1183014B1 (en) 1999-06-14 2003-10-08 Cosmo S.p.A. Controlled release and taste masking oral pharmaceutical compositions
ITMI991316A1 (it) 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
US7230088B2 (en) * 2001-07-03 2007-06-12 Mallinckrodt, Inc. Compounds for dual photodiagnosis and therapy
GB0224909D0 (en) * 2002-10-25 2002-12-04 Norgine Europe Bv Colon cleansing compositions
RU2253350C2 (ru) * 2003-06-30 2005-06-10 Государственное учреждение здравоохранения Иркутский Областной Диагностический Центр Способ эндоскопического исследования желудка
US20050244368A1 (en) * 2004-04-29 2005-11-03 Pashankar Dinesh S Pre-endoscopic use of polyethylene glycol compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070077202A1 (en) 2005-06-12 2007-04-05 Pentax Corporation Histostain composition for endoscope
WO2011107945A1 (en) * 2010-03-04 2011-09-09 Cosmo Technologies Ltd. Solid composition for the oral administration of dyes and diagnostic use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Mitooka 외. Gastrointestinal endoscopy, Vol. 41(5), 1995, pp. 454

Also Published As

Publication number Publication date
RU2649783C2 (ru) 2018-04-04
LT2908866T (lt) 2019-06-10
KR20150068412A (ko) 2015-06-19
CN112891563A (zh) 2021-06-04
AR091984A1 (es) 2015-03-18
US20230130628A1 (en) 2023-04-27
CA2886201A1 (en) 2014-04-24
TR201905800T4 (tr) 2019-05-21
AU2013331964A1 (en) 2015-04-09
PT2908866T (pt) 2019-05-24
FI3650048T3 (fi) 2025-05-26
MX361737B (es) 2018-12-14
ZA201502370B (en) 2016-11-30
HK1211465A1 (en) 2016-05-27
WO2014060199A1 (en) 2014-04-24
JP2015534956A (ja) 2015-12-07
JP6267210B2 (ja) 2018-01-24
IL237907A (en) 2017-06-29
HUE043112T2 (hu) 2019-08-28
DK3650048T3 (da) 2025-05-26
TW201420131A (zh) 2014-06-01
RS59152B1 (sr) 2019-10-31
EP2908866A1 (en) 2015-08-26
AU2013331964B2 (en) 2018-03-29
MX2015004935A (es) 2015-12-01
US20200129643A1 (en) 2020-04-30
EP3650048A1 (en) 2020-05-13
HRP20190710T1 (hr) 2019-08-23
BR112015008772A2 (pt) 2017-07-04
ES2721916T3 (es) 2019-08-06
US20250186626A1 (en) 2025-06-12
NZ706363A (en) 2019-03-29
CA2886201C (en) 2021-03-23
US20150283268A1 (en) 2015-10-08
RU2015118584A (ru) 2016-12-10
PL2908866T3 (pl) 2019-10-31
EP3650048B1 (en) 2025-03-05
IN2015DN02818A (https=) 2015-09-11
TWI651102B (zh) 2019-02-21
CN117462704A (zh) 2024-01-30
EP2908866B1 (en) 2019-02-27
ES3030697T3 (en) 2025-07-01
DK2908866T3 (da) 2019-05-06
EP2722058A1 (en) 2014-04-23
CN104755107A (zh) 2015-07-01

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