KR102200656B1 - 마이크로스피어를 포함하는 개선된 창상 치료 조성물 - Google Patents

마이크로스피어를 포함하는 개선된 창상 치료 조성물 Download PDF

Info

Publication number
KR102200656B1
KR102200656B1 KR1020157009202A KR20157009202A KR102200656B1 KR 102200656 B1 KR102200656 B1 KR 102200656B1 KR 1020157009202 A KR1020157009202 A KR 1020157009202A KR 20157009202 A KR20157009202 A KR 20157009202A KR 102200656 B1 KR102200656 B1 KR 102200656B1
Authority
KR
South Korea
Prior art keywords
microspheres
wound
pharmaceutical composition
wounds
delete delete
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020157009202A
Other languages
English (en)
Korean (ko)
Other versions
KR20150082207A (ko
Inventor
블라디미르 리터
메리 클레이만
데보라 하나 바르트펠트
에일론 아스쿨라이
Original Assignee
폴리힐 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 폴리힐 리미티드 filed Critical 폴리힐 리미티드
Publication of KR20150082207A publication Critical patent/KR20150082207A/ko
Application granted granted Critical
Publication of KR102200656B1 publication Critical patent/KR102200656B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020157009202A 2012-09-13 2013-09-12 마이크로스피어를 포함하는 개선된 창상 치료 조성물 Active KR102200656B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261700362P 2012-09-13 2012-09-13
US61/700,362 2012-09-13
PCT/IL2013/050774 WO2014041543A1 (en) 2012-09-13 2013-09-12 Improved wound healing compositions comprising microspheres

Publications (2)

Publication Number Publication Date
KR20150082207A KR20150082207A (ko) 2015-07-15
KR102200656B1 true KR102200656B1 (ko) 2021-01-11

Family

ID=50277729

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020157009202A Active KR102200656B1 (ko) 2012-09-13 2013-09-12 마이크로스피어를 포함하는 개선된 창상 치료 조성물

Country Status (17)

Country Link
US (1) US9370533B2 (cg-RX-API-DMAC10.html)
EP (1) EP2895209B1 (cg-RX-API-DMAC10.html)
JP (1) JP6104390B2 (cg-RX-API-DMAC10.html)
KR (1) KR102200656B1 (cg-RX-API-DMAC10.html)
AU (1) AU2013316718B2 (cg-RX-API-DMAC10.html)
BR (1) BR112015005335B1 (cg-RX-API-DMAC10.html)
CA (1) CA2883455C (cg-RX-API-DMAC10.html)
DK (1) DK2895209T3 (cg-RX-API-DMAC10.html)
ES (1) ES2748805T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20191804T1 (cg-RX-API-DMAC10.html)
HU (1) HUE047212T2 (cg-RX-API-DMAC10.html)
LT (1) LT2895209T (cg-RX-API-DMAC10.html)
MX (1) MX359713B (cg-RX-API-DMAC10.html)
PL (1) PL2895209T3 (cg-RX-API-DMAC10.html)
PT (1) PT2895209T (cg-RX-API-DMAC10.html)
RS (1) RS59410B1 (cg-RX-API-DMAC10.html)
WO (1) WO2014041543A1 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6893877B2 (ja) * 2014-10-29 2021-06-23 スペクトラル エムディー, インコーポレイテッドSpectral Md, Inc. 組織を分類するための反射モードマルチスペクトル時間分解型光学イメージングの方法および装置
CN110573066A (zh) 2017-03-02 2019-12-13 光谱Md公司 用于多光谱截肢部位分析的机器学习系统和技术
JP7186298B2 (ja) 2018-12-14 2022-12-08 スペクトラル エムディー,インコーポレイテッド 高精度マルチアパーチャスペクトルイメージングのためのシステムおよび方法
WO2020123724A1 (en) 2018-12-14 2020-06-18 Spectral Md, Inc. Machine learning systems and methods for assessment, healing prediction, and treatment of wounds
EP4314739A4 (en) 2021-03-30 2025-02-19 Spectral MD, Inc. SYSTEM AND METHOD FOR MULTISPECTRAL IMAGING WITH HIGH-PRECISION SNAPSHOT BASED ON MULTIPLEXED ILLUMINATION

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614310A (en) * 1994-11-04 1997-03-25 Minnesota Mining And Manufacturing Company Low trauma wound dressing with improved moisture vapor permeability
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
AU752255B2 (en) 1998-10-23 2002-09-12 Polyheal Ltd. Compositions of microspheres for wound healing
WO2002070523A1 (en) * 2001-03-07 2002-09-12 Pfizer Products Inc. Modulators of chemokine receptor activity
US7465463B2 (en) * 2002-09-04 2008-12-16 Polyheal, Ltd. Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues
JP2009525975A (ja) * 2006-01-31 2009-07-16 ヴァション,デイビッド 多細胞生物の組織の治癒を促進するための組成物及びその方法
GB0607774D0 (en) * 2006-04-20 2006-05-31 Renovo Group Plc Medicaments

Also Published As

Publication number Publication date
JP2015528492A (ja) 2015-09-28
BR112015005335A2 (pt) 2017-07-04
PL2895209T3 (pl) 2020-01-31
HRP20191804T1 (hr) 2019-12-27
JP6104390B2 (ja) 2017-03-29
KR20150082207A (ko) 2015-07-15
WO2014041543A1 (en) 2014-03-20
BR112015005335B1 (pt) 2020-03-10
ES2748805T3 (es) 2020-03-18
HK1212638A1 (en) 2016-06-17
EP2895209A1 (en) 2015-07-22
CA2883455A1 (en) 2014-03-20
EP2895209B1 (en) 2019-07-17
US20150231170A1 (en) 2015-08-20
US9370533B2 (en) 2016-06-21
PT2895209T (pt) 2019-10-28
BR112015005335A8 (pt) 2018-01-30
CA2883455C (en) 2020-01-28
HUE047212T2 (hu) 2020-04-28
MX359713B (es) 2018-10-08
LT2895209T (lt) 2019-10-25
DK2895209T3 (da) 2019-10-21
RS59410B1 (sr) 2019-11-29
MX2015002816A (es) 2015-05-15
AU2013316718B2 (en) 2016-09-29
EP2895209A4 (en) 2016-04-20
AU2013316718A1 (en) 2015-03-12

Similar Documents

Publication Publication Date Title
KR102132543B1 (ko) 양이온성 살생물제를 포함하는 페트롤라툼-계 조성물
Khorasani et al. Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study
JP6778219B2 (ja) 皮膚の炎症を抑制するイガイ接着タンパク質製品及びその適用
JP2021520373A (ja) Cgrpを阻害する際に使用するための神経毒素
US20260137839A1 (en) Controlled hydrogel delivery of focal adhesion kinase inhibitor for decreased scar formation
AU2013316718B2 (en) Improved wound healing compositions comprising microspheres
JP2019206544A (ja) 次亜塩素酸ナトリウムを含む抗炎症溶液
CN116531369A (zh) 一种化合物在促进伤口愈合药物中的应用
Serafini et al. Recent patents on medicinal plants/natural products as a therapeutic approach to wounds and burns healing
US20220249734A1 (en) Powdered collagen wound care compositions
EP3087990B1 (en) Gel-forming powder comprising sulfamonomethoxine and chitosan for treating wounds
RU2286781C2 (ru) Способ лечения химических ожогов пищевода у детей
RU2173155C1 (ru) Ранозаживляющий, противовоспалительный и противоинфекционный лекарственный препарат
HK1212638B (en) Improved wound healing compositions comprising microspheres
US20250367224A1 (en) Galactose and fucose monosaccharides for re-epithelialization and treating lesions
EP4659751A1 (en) Galactose and fucose monosaccharides for re-epithelialization and treating lesions
CN115245502B (zh) 滴喷剂型纳米脂质体凝胶三伏贴
CN112316108A (zh) 促进及治疗慢性伤口愈合的组合物和方法
Palácio et al. Wound healing effects of β-lapachone-loaded liposomal hydrogel based on bacterial cellulose and hydroxyethylcellulose
KR101607229B1 (ko) 말기름을 함유하는 상처 치료용 조성물
KR102644156B1 (ko) 피부 상처 또는 화상 치료 작용제
Sar Development and characterisation of metformin loaded film with flaxseed gel for acceleration of healing process of burn wounds: an approach for tissue regeneration
CN117617500A (zh) 一种适用于术后恢复的功能型配方粉及其制备方法和用法

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 6