KR102167464B1 - 마이크로 니들 시트 및 경피 투여용 첩부제 - Google Patents
마이크로 니들 시트 및 경피 투여용 첩부제 Download PDFInfo
- Publication number
- KR102167464B1 KR102167464B1 KR1020167034984A KR20167034984A KR102167464B1 KR 102167464 B1 KR102167464 B1 KR 102167464B1 KR 1020167034984 A KR1020167034984 A KR 1020167034984A KR 20167034984 A KR20167034984 A KR 20167034984A KR 102167464 B1 KR102167464 B1 KR 102167464B1
- Authority
- KR
- South Korea
- Prior art keywords
- skin
- sheet
- stratum corneum
- microneedle
- microneedles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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- 239000010410 layer Substances 0.000 description 21
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- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
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- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
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- 239000004373 Pullulan Substances 0.000 description 1
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- 238000012661 block copolymerization Methods 0.000 description 1
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
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- 230000001815 facial effect Effects 0.000 description 1
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- 229940096919 glycogen Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
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- 230000009993 protective function Effects 0.000 description 1
- 235000019423 pullulan Nutrition 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- BTURAGWYSMTVOW-UHFFFAOYSA-M sodium dodecanoate Chemical compound [Na+].CCCCCCCCCCCC([O-])=O BTURAGWYSMTVOW-UHFFFAOYSA-M 0.000 description 1
- 229940082004 sodium laurate Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2014-119370 | 2014-06-10 | ||
| JP2014119370A JP6023752B2 (ja) | 2014-06-10 | 2014-06-10 | マイクロニードルシート及び経皮投与用貼付剤 |
| PCT/JP2015/065842 WO2015190344A1 (ja) | 2014-06-10 | 2015-06-02 | マイクロニードルシート及び経皮投与用貼付剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20170019357A KR20170019357A (ko) | 2017-02-21 |
| KR102167464B1 true KR102167464B1 (ko) | 2020-10-19 |
Family
ID=54833440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167034984A Active KR102167464B1 (ko) | 2014-06-10 | 2015-06-02 | 마이크로 니들 시트 및 경피 투여용 첩부제 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20170106180A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3156097A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6023752B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102167464B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN106456955B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015190344A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210322746A1 (en) * | 2018-08-28 | 2021-10-21 | Nissha Co., Ltd. | Skin quality-improving sheet |
| WO2020092229A1 (en) * | 2018-10-31 | 2020-05-07 | The Regents Of The University Of California | Biodegradable microneedles for transdermal therapeutic agent delivery |
| CN111408032A (zh) * | 2020-03-05 | 2020-07-14 | 优微（珠海）生物科技有限公司 | 一种透气透水微针贴片及其使用方法 |
| CN112618945B (zh) * | 2020-12-14 | 2022-06-21 | 北京航空航天大学 | 中空封闭型微针及其制备方法和包括该微针的操作装置 |
| GB2622416B (en) * | 2022-09-15 | 2025-04-02 | Ndm Tech Ltd | Skin preparation device |
| TWI824724B (zh) * | 2022-09-16 | 2023-12-01 | 達運精密工業股份有限公司 | 微針貼片、其製造模具、以及其製造方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007089792A (ja) | 2005-09-28 | 2007-04-12 | Nano Device & System Research Inc | 経皮投与装置 |
| JP2014079557A (ja) | 2012-09-28 | 2014-05-08 | Kosumedei Seiyaku Kk | 段差に薬物を保持したマイクロニードル |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2563450T (pt) * | 2010-04-28 | 2017-08-28 | Kimberly Clark Co | Dispositivo para entrega de medicação para a artrite reumatóide |
| JP6121734B2 (ja) * | 2012-02-09 | 2017-04-26 | 久光製薬株式会社 | マイクロニードル用ゾルミトリプタン含有コーティング組成物及びマイクロニードルデバイス |
| ES2730735T3 (es) * | 2012-04-25 | 2019-11-12 | Medrx Co Ltd | Microaguja y matriz de microagujas |
| CN203355123U (zh) * | 2013-06-13 | 2013-12-25 | 陈彦彪 | 一种超微针片 |
-
2014
- 2014-06-10 JP JP2014119370A patent/JP6023752B2/ja active Active
-
2015
- 2015-06-02 CN CN201580031084.8A patent/CN106456955B/zh active Active
- 2015-06-02 WO PCT/JP2015/065842 patent/WO2015190344A1/ja not_active Ceased
- 2015-06-02 US US15/317,906 patent/US20170106180A1/en not_active Abandoned
- 2015-06-02 EP EP15806520.1A patent/EP3156097A1/en not_active Withdrawn
- 2015-06-02 KR KR1020167034984A patent/KR102167464B1/ko active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007089792A (ja) | 2005-09-28 | 2007-04-12 | Nano Device & System Research Inc | 経皮投与装置 |
| JP2014079557A (ja) | 2012-09-28 | 2014-05-08 | Kosumedei Seiyaku Kk | 段差に薬物を保持したマイクロニードル |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3156097A1 (en) | 2017-04-19 |
| CN106456955B (zh) | 2018-09-25 |
| CN106456955A (zh) | 2017-02-22 |
| JP2015231466A (ja) | 2015-12-24 |
| WO2015190344A1 (ja) | 2015-12-17 |
| US20170106180A1 (en) | 2017-04-20 |
| JP6023752B2 (ja) | 2016-11-09 |
| KR20170019357A (ko) | 2017-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20161214 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| A302 | Request for accelerated examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20200427 Comment text: Request for Examination of Application |
|
| PA0302 | Request for accelerated examination |
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