KR102154810B1 - The Method for Photochromic soft Contact Lens and Photochromic soft Contact Lens - Google Patents
The Method for Photochromic soft Contact Lens and Photochromic soft Contact Lens Download PDFInfo
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- KR102154810B1 KR102154810B1 KR1020180148439A KR20180148439A KR102154810B1 KR 102154810 B1 KR102154810 B1 KR 102154810B1 KR 1020180148439 A KR1020180148439 A KR 1020180148439A KR 20180148439 A KR20180148439 A KR 20180148439A KR 102154810 B1 KR102154810 B1 KR 102154810B1
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- 238000000576 coating method Methods 0.000 claims abstract description 16
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- 238000002845 discoloration Methods 0.000 claims abstract description 11
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 8
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- 238000007649 pad printing Methods 0.000 claims abstract description 7
- 238000001035 drying Methods 0.000 claims abstract description 5
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- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 6
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- CQTRKDFIQFOAQV-UHFFFAOYSA-N 1',3',3'-trimethylspiro[benzo[f][1,4]benzoxazine-3,2'-indole] Chemical compound C1=CC=CC2=C(N=CC3(C(C)(C)C4=CC=CC=C4N3C)O3)C3=CC=C21 CQTRKDFIQFOAQV-UHFFFAOYSA-N 0.000 claims description 3
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- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
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- B29D11/00009—Production of simple or compound lenses
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- B29D11/00048—Production of contact lenses composed of parts with dissimilar composition
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- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00634—Production of filters
- B29D11/00653—Production of filters photochromic
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B29D11/00009—Production of simple or compound lenses
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- B29D11/00009—Production of simple or compound lenses
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- B29D11/00125—Auxiliary operations, e.g. removing oxygen from the mould, conveying moulds from a storage to the production line in an inert atmosphere
- B29D11/00134—Curing of the contact lens material
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- B29D11/00009—Production of simple or compound lenses
- B29D11/00317—Production of lenses with markings or patterns
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00865—Applying coatings; tinting; colouring
- B29D11/00894—Applying coatings; tinting; colouring colouring or tinting
- B29D11/00903—Applying coatings; tinting; colouring colouring or tinting on the surface
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- C—CHEMISTRY; METALLURGY
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/04—Homopolymers or copolymers of esters
- C08L33/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
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- C—CHEMISTRY; METALLURGY
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- C08L39/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions of derivatives of such polymers
- C08L39/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
- C08L39/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
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- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D175/00—Coating compositions based on polyureas or polyurethanes; Coating compositions based on derivatives of such polymers
- C09D175/04—Polyurethanes
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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- C09D4/00—Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond ; Coating compositions, based on monomers of macromolecular compounds of groups C09D183/00 - C09D183/16
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- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/26—Thermosensitive paints
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- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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- G—PHYSICS
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- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
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Abstract
본 발명은 광변색 소프트 콘택트렌즈 및 이의 제조 방법에 관한 것으로, 하형 몰드에 교반한 렌즈원료를 넣는 제 1단계와 상형몰드와 하형몰드를 압착하여 120℃의 열 오븐에 넣고 60~90분 동안 중합하는 제 2단계와 상형몰드와 하형몰드를 분리하여 상기 상형몰드에 압착되어 안착된 렌즈를 건조시켜 드라이 렌즈를 얻는 제 3단계와 변색염료가 도포된 실리콘 패드를 이용하여 상기 드라이 렌즈 외측부 동공부분으로 찍어 도포하는 제 4단계와 상기 변색염료가 도포된 렌즈 부분에 코팅액이 도포된 실리콘 패드를 이용하여 추가적으로 코팅액을 덮어 씌우는 제 5단계와 코팅액이 씌워진 렌즈를 120℃의 열 오븐에 넣고 60~90분 동안 건조한 후 상기 상형몰드에서 분리하여 취득한 후 염화나트륨 0.9중량% 생리 식염수에 20~25시간 동안 수화 시킨 후 콘택트렌즈 보존액에 보관하는 제 6단계로 구성되어, 변색염료를 소프트 콘택트렌즈 외측부 동공 예상 위치에 패드 프린팅하여 햇빛에 노출되었을 때 해당 부위가 변색되면서 색상이 어두워지게 함으로써 편안한 시야를 제공하여 눈의 피로감을 줄일 수 있게 하고, 또한 변색염료가 눈에 직접 닿지 않게 제조되어 신체적 안전성을 현저하게 높일 수 있는 효과를 제공한다.The present invention relates to a photochromic soft contact lens and a method of manufacturing the same, and the first step of putting the agitated lens material into the lower mold, and the upper mold and the lower mold are compressed and put into a heat oven at 120° C. and polymerized for 60 to 90 minutes. The second step of separating the upper mold and the lower mold, and the third step of drying the lens pressed and seated on the upper mold to obtain a dry lens, and the outer pupil of the dry lens using a silicone pad coated with a color change dye. The fourth step of dipping and applying, the fifth step of additionally covering the coating liquid using a silicone pad coated with the coating liquid on the lens portion coated with the discoloration dye, and placing the lens covered with the coating liquid in a heat oven at 120℃ for 60 to 90 minutes After drying for a period of time, it is separated from the upper mold, obtained, hydrated in sodium chloride 0.9% by weight physiological saline for 20 to 25 hours, and then stored in a contact lens preservative solution.The discoloration dye is placed in the expected position of the pupil in the outer part of the soft contact lens. When exposed to sunlight through pad printing, the area becomes discolored and the color darkens, providing a comfortable view to reduce eye fatigue.Also, it is manufactured so that the discoloration dye does not come into direct contact with the eyes, thus significantly enhancing physical safety. It provides a good effect.
Description
본 발명은 광변색 소프트 콘택트렌즈 및 이의 제조 방법에 관한 것으로, 보다 상세하게는 변색염료를 소프트 콘택트렌즈 외측부 동공 예상 위치에 패드 프린팅하여 자외선에 노출 시 해당 부위가 변색되면서 색상이 어두워지게 함으로써 편안한 시야를 제공하여 눈의 피로감을 줄일 수 있고, 또한 변색염료가 눈에 직접 닿지 않게 하여 신체적 안전성을 높일 수 있는 광변색 소프트 콘택트렌즈 및 이의 제조 방법에 관한 것이다.The present invention relates to a photochromic soft contact lens and a method of manufacturing the same, and more particularly, by pad-printing a color change dye at the expected position of the pupil on the outer side of the soft contact lens, and when exposed to ultraviolet rays, the corresponding part is discolored and the color becomes dark. The present invention relates to a photochromic soft contact lens and a method of manufacturing the same, which can reduce eye fatigue by providing a photochromic soft contact lens and improve physical safety by preventing a discoloration dye from directly contacting the eye.
일반적으로 빛은 파장에 따라서 자외선, 가시광선, 적외선으로 나눌 수 있고 이는 실외에서 끊임없는 빛의 변화에 따라 적응해야하기 때문에 눈의 피로는 점점 커지고 시력이 떨어지는 악순환이 발생될 수 있다. 급격한 빛의 변화에 따른 자극으로부터 눈을 보호하고 편안한 시야를 제공하기 위한 기능성 렌즈로써 변색 렌즈가 제공되고 있다. 변색렌즈는 실외에서 활동 시나 실내에서 실외로 이동 시 자외선량과 같은 환경 조건에 따라 렌즈의 농도가 변화되면서 눈으로 들어오는 빛의 양을 조절하고 자외선을 차단하여 눈의 스트레스와 자극을 줄여줄 수 있게 된다. 즉 햇빛에 노출되면 렌즈가 변색되고 햇빛이 차단되면 원상태로 복귀되는 광화학적가역반을을 일으키는 화합물을 이용하여 기능을 제공하게 된다.In general, light can be divided into ultraviolet light, visible light, and infrared light depending on the wavelength, and since it must be adapted according to the constant change of light outdoors, eye fatigue may increase and a vicious cycle may occur that eyesight decreases. A color-changing lens is being provided as a functional lens to protect the eyes from irritation caused by rapid light changes and to provide a comfortable view. Color-changing lenses are designed to reduce eye stress and irritation by controlling the amount of light entering the eyes and blocking ultraviolet rays as the concentration of the lens changes according to environmental conditions such as the amount of ultraviolet rays when active outdoors or when moving from indoors to outdoors. do. In other words, when exposed to sunlight, the lens is discolored, and when sunlight is blocked, the function is provided by using a compound that causes photochemical reversibility that returns to its original state.
이와 관련하여, 대한민국 등록특허공보 제10-0779990호에서는 미러 코팅된 광변색 선글라스 렌즈에 있어서 하드 코팅된 광변색 렌즈 앞면은 서로 다른 두께의 SiO2 유전체 박막이 전후면으로 둘러싸인 크롬(Cr) 금속 박막을 증착하고, 뒷면은 반사방지 코팅(anti-reflection coating) 처리하고, 최종적으로 렌즈 양면을 수막 코팅 처리하는 구성을 게시하고 있다.In this regard, in Korean Patent Publication No. 10-0779990, in the mirror-coated photochromic sunglasses lens, the front surface of the hard-coated photochromic lens is a chromium (Cr) metal thin film surrounded by SiO2 dielectric thin films of different thicknesses. It has been evaporated, the back side is treated with anti-reflection coating, and finally both sides of the lens are treated with a water film.
그러나 상기한 미러 코팅된 광변색 선글라스 렌즈는 일반 안경에 적용될 수 있는 렌즈에 관한 발명으로써 광변색이 가능한 콘택트렌즈 제조 방법으로의 사용이 어려운 문제점이 있다.However, the above-described mirror-coated photochromic sunglasses lens is an invention for a lens that can be applied to general eyeglasses, and it is difficult to use it as a method of manufacturing a photochromic contact lens.
상기한 바와 같은 문제점을 해결하기 위하여 일반 안경렌즈용이 아닌 콘택트렌즈를 대상으로 소프트 콘택트렌즈에 변색염료를 렌즈 동공이 위치되는 외측부에 패드 프린팅하여 눈에 직접 닿지 않게 하여 신체적 안전성을 확보하고 변색염료 함량에 따라 변색 농도가 변화될 수 있는 광변색 소프트 콘택트렌즈 및 이의 제조 방법을 제공하는 것을 목적으로 한다.In order to solve the above problems, a color change dye is applied to the soft contact lens for contact lenses that are not for general spectacle lenses, and the color change dye is printed on the outer part where the lens pupil is located so that it does not come into direct contact with the eyes to ensure physical safety, and the color change dye content. An object of the present invention is to provide a photochromic soft contact lens and a method of manufacturing the same, in which the color change density can be changed according to the present invention.
목적을 달성하기 위한 구성으로는 광변색 소프트 콘택트렌즈 제조방법에 있어서, 하형 몰드에 교반한 렌즈원료를 넣는 제 1단계와 상형몰드와 하형몰드를 압착하여 120℃의 열 오븐에 넣고 60~90분 동안 중합하는 제 2단계와 상형몰드와 하형몰드를 분리하여 상기 상형몰드에 압착되어 안착된 렌즈를 건조시켜 드라이 렌즈를 얻는 제 3단계와 변색염료가 도포된 실리콘 패드를 이용하여 상기 드라이 렌즈 외측부 동공부분으로 찍어 도포하는 제 4단계와 상기 변색염료가 도포된 렌즈 부분에 코팅액이 도포된 실리콘 패드를 이용하여 코팅액을 변색염료 위에 덮어씌우는 제 5단계와 코팅액이 씌워진 렌즈를 120℃의 열 오븐에 넣고 60~90분 동안 건조한 후, 상기 상형몰드에서 분리하여 취득한 후 염화나트륨 0.9중량% 생리 식염수에 20~25시간 동안 수화 시킨 후 콘택트렌즈 보존액에 보관하는 제 6단계로 구성된다. 상기 렌즈원료는 친수성 모노머 2-Hydroxyethyl methacrylate(HEMA) 96.20중량%와 Methacrylic acid(MA) 1.80 중량%, 가교제 Ethylene glycol Dimethacrylate(EGDMA) 0.4중량%, 개시제 2,5-Dimethyl-2,5-di(2-ethylhexanoylperoxy)hexane(LUPEROX 256) 0.60중량%와 UV차단제 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00중량%의 구성으로 혼합하여 30분 동안 200rpm으로 교반하여 이루어진다.To achieve the purpose, in the photochromic soft contact lens manufacturing method, the first step of putting the agitated lens material into the lower mold, the upper mold and the lower mold are compressed and put in a heat oven at 120°C for 60 to 90 minutes. During the second step of polymerization, the third step of obtaining a dry lens by separating the upper mold and the lower mold, and drying the lens pressed and seated on the upper mold, and the outer pupil of the dry lens using a silicone pad coated with a color change dye. The fourth step of dipping and applying the part and the fifth step of covering the coating liquid over the color-changing dye using a silicone pad coated with the coating liquid on the lens part coated with the color-changing dye, and putting the lens covered with the coating liquid in a heat oven at 120°C. After drying for 60 to 90 minutes, it is separated from the upper mold, obtained, hydrated in 0.9 wt% sodium chloride physiological saline for 20 to 25 hours, and then stored in a contact lens preservation solution. The lens material is a hydrophilic monomer 2-Hydroxyethyl methacrylate (HEMA) 96.20% by weight and Methacrylic acid (MA) 1.80% by weight, crosslinking agent Ethylene glycol Dimethacrylate (EGDMA) 0.4% by weight, initiator 2,5-Dimethyl-2,5-di ( 2-ethylhexanoylperoxy)hexane (LUPEROX 256) 0.60% by weight and UV blocking agent 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00% by weight of the mixture and stirred at 200rpm for 30 minutes It is done by doing.
본 발명의 다른 특징으로는 렌즈 앞부분에 광변색 기능을 위한 변색염료 동공크기로 패드 프린팅하여 눈과 직접적으로 닿지 않게 하여 안전성을 확보한다.Another feature of the present invention is to secure safety by printing a pad on the front of the lens with a pupil size of a color change dye for a photochromic function so that it does not come into direct contact with the eyes.
본 발명의 또 다른 특징으로는 변색원료의 혼합 중량 비율에 따른 광변색 농도를 조절할 수 있으며, 패드 프린팅 시 패드 모양에 따라 여러 가지 모양으로 제조가 가능하다.As another feature of the present invention, it is possible to adjust the photochromic density according to the mixing weight ratio of the discoloring raw material, and it is possible to manufacture various shapes according to the shape of the pad during pad printing.
상기한 바와 같이, 광변색 소프트 콘택트렌즈 및 이의 제조 방법을 통해 변색염료를 소프트 콘택트렌즈 외측부 동공 예상 위치에 패드 프린팅하여 햇빛에 노출되었을 때 해당 부위가 변색되면서 색상이 어두워지게 함으로써 편안한 시야를 제공하여 눈의 피로감을 줄일 수 있게 하고, 또한 자외선을 차단하는 기능과 함께 변색염료가 눈에 직접 닿지 않게 제조되어 신체적 안전성을 현저하게 높일 수 있는 효과를 제공한다.As described above, through the photochromic soft contact lens and its manufacturing method, the color change dye is pad-printed on the expected position of the pupil on the outer side of the soft contact lens, and the color becomes dark when the area is discolored when exposed to sunlight, thereby providing a comfortable view. It is possible to reduce eye fatigue and also provides an effect that can significantly increase physical safety as it is manufactured not to directly contact the eyes with discoloration dyes along with the function of blocking ultraviolet rays.
도 1은 본 발명의 바람직한 실시 예에 따른 광변색 소프트 콘택트렌즈 제조 방법 순서도.
도 2는 본 발명의 바람직한 실시 예에 따른 콘택트렌즈 크기 및 광변색 기능 부분 크기를 나타내는 표시도.
도 3은 본 발명의 광변색 소프트 콘택트렌즈 제조 방법으로 제조된 광변색 소프트 콘택트렌즈의 가시광선 투과율 결과.1 is a flow chart of a method of manufacturing a photochromic soft contact lens according to a preferred embodiment of the present invention.
2 is a display diagram showing the size of a contact lens and the size of a photochromic function part according to a preferred embodiment of the present invention.
3 is a result of visible light transmittance of a photochromic soft contact lens manufactured by the method of manufacturing a photochromic soft contact lens of the present invention.
이하, 본 발명의 실시 예를 첨부된 도면을 참조로 상세히 설명한다. Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
도 1은 본 발명에 따른 바람직한 실시 예에 따른 광변색 소프트 콘택트렌즈 제조 방법 순서도로써, 이를 참고하여 본원발명의 상세 구성을 설명하면 아래와 같다.1 is a flowchart illustrating a method of manufacturing a photochromic soft contact lens according to a preferred embodiment of the present invention, and a detailed configuration of the present invention will be described with reference to this.
광변색 소프트 콘택트렌즈 제조 방법에 있어서, 하형 몰드에 교반한 렌즈원료를 넣는 제 1단계(S10)와 상형몰드와 하형몰드를 압착하여 120℃의 열 오븐에 넣고 60~90분 동안 중합하는 제 2단계(S20)와 상형몰드와 하형몰드를 분리하여 상기 상형몰드에 압착되어 안착된 렌즈를 건조시켜 드라이 렌즈를 얻는 제 3단계(S30)와 변색염료가 도포된 실리콘 패드를 이용하여 상기 드라이 렌즈 외측부 동공부분으로 찍어 도포하는 제 4단계(S40)와 상기 변색염료가 도포된 렌즈 부분에 코팅액이 도포된 실리콘 패드를 이용하여 코팅액을 변색염료 위에 덮어씌우는 제 5단계(S50)와 코팅액이 씌워진 렌즈를 120℃의 열 오븐에 넣고 60~90분 동안 건조한 후 상기 상형몰드에서 분리하여 취득한 후 염화나트륨 0.9중량% 생리 식염수에 20~25시간 동안 수화 시킨 후 콘택트렌즈 보존액에 보관하는 제 6단계(S60)로 이루어지게 된다.In the photochromic soft contact lens manufacturing method, the first step (S10) of putting the stirred lens material into the lower mold, and the second step of compressing the upper mold and the lower mold, putting them in a heat oven at 120°C, and polymerizing them for 60 to 90 minutes. Step (S20) and the third step (S30) of obtaining a dry lens by separating the upper mold and the lower mold to dry the lens pressed and seated on the upper mold, and the outer portion of the dry lens using a silicone pad coated with a color change dye. The fourth step (S40) of dipping into the pupil and applying the coating liquid over the color-changing dye using a silicone pad coated with the coating liquid on the lens portion coated with the color-changing dye (S50), and the lens covered with the coating liquid. Put in a heat oven at 120°C, dry for 60 to 90 minutes, separate and obtain from the upper mold, hydrate in sodium chloride 0.9% by weight physiological saline for 20 to 25 hours, and store in a contact lens preservation solution to step 6 (S60). Will come true.
상기 렌즈원료는 친수성 모노머 2-Hydroxyethyl methacrylate(HEMA) 96.20중량%와 Methacrylic acid(MA) 1.80 중량%, 가교제 Ethylene glycol Dimethacrylate(EGDMA) 0.4중량%, 개시제 2,5-Dimethyl-2,5-di(2-ethylhexanoylperoxy)hexane(LUPEROX 256) 0.60중량%와 UV차단제 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00중량%의 구성으로 혼합하여 30분 동안 200rpm으로 교반하여 이루어지고, 상기 변색염료는 렌즈에 탄성을 부여하며 수분을 흡수하는 습윤성 우레탄 35중량%와 함께 습윤성 폴리머로 수분을 머금을 수 있는 PVP(Polyvinyl pirrolidone) 25중량%와 변색원료인 1,3,3-Trimethylindolinonaphthospirooxazine 10중량%를 첨가하며 패드 프린팅에 적당한 점도를 부여하는 용제로 Cyclohexanone와 Cyclopentanone 중 하나를 30중량%로 구성하여 사용하게 된다. 광변색 변색원료로는 spiropyran, spirooxazine, chromenes, diarylethene과 같은 유기 광변색 염료 분자를 이용할 수 있는데, 본원발명에서는 spirooxazine 유형의 염료를 활용한다.The lens material is a hydrophilic monomer 2-Hydroxyethyl methacrylate (HEMA) 96.20% by weight and Methacrylic acid (MA) 1.80% by weight, crosslinking agent Ethylene glycol Dimethacrylate (EGDMA) 0.4% by weight, initiator 2,5-Dimethyl-2,5-di ( 2-ethylhexanoylperoxy)hexane (LUPEROX 256) 0.60% by weight and UV blocking agent 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00% by weight of the mixture and stirred at 200rpm for 30 minutes The discoloration dye includes 35% by weight of wettable urethane that imparts elasticity to the lens and absorbs moisture, 25% by weight of PVP (Polyvinyl pirrolidone) capable of retaining moisture with a wettable polymer, and 1,3, which is a color change material, 10% by weight of 3-Trimethylindolinonaphthospirooxazine is added, and one of Cyclohexanone and Cyclopentanone is used in 30% by weight as a solvent that provides a suitable viscosity for pad printing. Organic photochromic dye molecules such as spiropyran, spirooxazine, chromenes, and diarylethene can be used as the photochromic discoloration raw material, and spirooxazine-type dyes are used in the present invention.
도 2는 본 발명에 따른 본 발명의 바람직한 실시 예에 따른 콘택트렌즈 크기 및 광변색 기능 부분 크기를 나타내는 것으로, 상기 변색염료가 패드 프린팅 되는 렌즈 외측부의 범위는 사람의 동공 위치와 크기에 대응될 수 있는 부위로 직경이 2mm~10mm의 범위가 될 수 있도록 구성된다. 콘택트렌즈 동공 부분으로 광변색 기능이 제공되는 특징을 위해서 소프트 콘택트렌즈 크기를 14.0~14.5mm로 제조하고, 광변색 기능을 위해 콘택트렌즈를 착용하였을 시 동공이 위치하는 부위의 콘택트렌즈 외측부에 변색염료를 패드 프린팅 하는데 이는 평균 사람의 동공 크기가 2~6mm이지만 환한 공간에서 갑자기 어두운 공간으로 갔을 때 시각적으로 적응하기 위한 암순응의 과정을 거칠 시 동공이 10mm까지 커질 수 있는 범위에 대응하기 위한 크기로 제작될 수 있다. 패드 프린팅을 통해 변색염료를 제조된 렌즈 외측부에 전사할 시, 패드 모양에 따라 원형, 타원형, 네모, 세모, 별 모양 중에서 선택적으로 제조될 수 있는 것을 특징으로 한다. 2 is a view showing the size of the contact lens and the size of the photochromic function part according to a preferred embodiment of the present invention. The range of the outer part of the lens on which the color change dye is pad-printed may correspond to the position and size of a human pupil. It is configured so that the diameter can be in the range of 2mm to 10mm. The soft contact lens size is 14.0~14.5mm for the feature that the photochromic function is provided to the pupil of the contact lens.When the contact lens is worn for the photochromic function, a discoloration dye on the outer part of the contact lens where the pupil is located. The average person's pupil size is 2~6mm, but it is made to respond to the range in which the pupil can grow up to 10mm when going through a dark adaptation process to visually adapt when going from a bright space to a dark space. Can be. When the discoloration dye is transferred to the outer part of the manufactured lens through pad printing, it is characterized in that it can be selectively manufactured from a circle, an oval, a square, a triangle, and a star according to the shape of the pad.
상기 코팅액은 에틸렌옥사이드(Ethylene oxide)를 포함하는 올리고머(oligomer) 44중량%에 열가소성 우레탄(thermoplastic urethane) 28중량%와 솔벤트(solvent) 28중량%를 첨가하여 기본 혼합물을 생성하고, 상기 혼합물을 50 ~ 70℃로 가열 후 교반기를 사용하여 50 ~ 80rpm으로 28 ~ 32분간 교반한 후 상온으로 냉각하여 제조되어 콘택트렌즈의 변색염료 층 위에 코팅되어 색감을 유지하고 컬러 콘택트렌즈의 투명성을 확보할 수 있다. 코팅액 또한 변색염료와 동일하게 패드 프린팅 기법으로 소프트 콘택트렌즈에 씌우게 된다,The coating solution was prepared by adding 28% by weight of a thermoplastic urethane and 28% by weight of a solvent to 44% by weight of an oligomer containing ethylene oxide to form a basic mixture. It is manufactured by heating to ~70℃ and then stirring at 50~80rpm for 28~32 minutes using a stirrer and then cooling to room temperature.It is coated on the color change dye layer of contact lenses to maintain color and secure transparency of color contact lenses. . The coating solution is also applied to the soft contact lenses by pad printing technique in the same way as the color change dye.
변색염료로 구성되는 바인더와 변색원료, 용제의 성분조성 중량%는 사용자에게 최적화 된 기능과 안전성을 제공할 수 있도록 실시 예와 다른 비율로 조정될 수 있다. 성분 조성에 대해 상세히 설명하면 렌즈에 탄성을 부여하며 수분을 흡수하는 습윤성 우레탄은 10~50중량%의 범위를 가질 수 있고 이와 함께 PVP(Polyvinyl pirrolidone)는 5~30중량%로 혼합되어 바인더로 사용될 수 있다. 또한 변색원료인 1,3,3-Trimethylindolinonaphthospirooxazine는 10~50중량%의 범위를 가질 수 있고 패드 프리닝에 점도를 부여할 수 있는 Cyclohexanone 또는 Cyclopentanone은 5~40중량%로 구성될 수 있다. 이는 전체 100중량%를 이룰 수 있도록 구성성분의 중량비 범위 내에서 선택적으로 혼합하여 변색염료를 제조할 수 있다.The weight percent of the composition of the binder, the color change material, and the solvent composed of the color change dye may be adjusted in a different ratio than that of the embodiment so as to provide the user with optimized functions and safety. If the component composition is described in detail, the wettability urethane that imparts elasticity to the lens and absorbs moisture may have a range of 10 to 50% by weight, and PVP (Polyvinyl pirrolidone) is mixed in 5 to 30% by weight to be used as a binder. I can. In addition, 1,3,3-Trimethylindolinonaphthospirooxazine, which is a discoloration material, may have a range of 10 to 50% by weight, and Cyclohexanone or Cyclopentanone, which can impart viscosity to the pad frying, may be composed of 5 to 40% by weight. This can be selectively mixed within the range of the weight ratio of the constituents so as to achieve a total of 100% by weight to prepare a color change dye.
도 3은 본 발명의 광변색 소프트 콘택트렌즈 제조 방법으로 제조된 광변색 소프트 콘택트렌즈의 가시광선 투과율 결과를 나타낸 것으로 381~780nm 파장의 가시광선 투과율에 대해 FDA 기준을 만족하는 90% 이상의 결과 값을 획득하였고, 또한 자외선 차단율의 경우에도 FDA 기준의 Class 2등급을 만족하게 된다. 이에 대한 상세 자료는 아래 표와 같다.Figure 3 shows the visible light transmittance results of the photochromic soft contact lens manufactured by the method of manufacturing a photochromic soft contact lens of the present invention. The result value of 90% or more satisfying FDA standards for visible light transmittance of 381 to 780 nm wavelength. It was obtained, and also satisfies the class 2 of the FDA standard in the case of UV blocking rate. Detailed data for this are shown in the table below.
구분
division
가시광선투과율
Visible light transmittance
UV-A 차단율
UV-A blocking rate
UV-B 차단율
UV-B blocking rate
파장
wavelength
381~780nm
381~780nm
316~380nm
316~380nm
280~315nm
280~315nm
FDA 기준
FDA standard
90 이상
over 90
Class 2등급
70% 이상
Class 2
70% or more
Class 2등급
70% 이상
Class 2
70% or more
결과값
Result
99.7448
99.7448
87.20
87.20
98.79
98.79
본 발명은 특정의 실시 예 및 적용 예와 관련하여 도시 및 설명하였지만, 첨부된 특허청구범위에 의해 나타난 발명의 사상 및 영역으로부터 벗어나지 않는 한도 내에서 다양한 개조 및 변화 가능하다는 것을 당 업계에서 통상의 지식을 가진 자라면 누구나 쉽게 알 수 있을 것이다.Although the present invention has been shown and described in connection with specific embodiments and application examples, it is common knowledge in the art that various modifications and changes are possible within the limit without departing from the spirit and scope of the invention indicated by the appended claims. Anyone who possesses will know it easily.
S10. 제 1단계 S20. 제 2단계
S30. 제 3단계 S40. 제 4단계
S50. 제 5단계 S60. 제 6단계S10. The first step S20. Step 2
S30. The third step S40. Step 4
S50. The fifth step S60. Step 6
Claims (7)
하형 몰드에 교반한 렌즈원료를 넣는 제 1단계(S10);와
상형몰드와 하형몰드를 압착하여 120℃의 열 오븐에 넣고 60~90분 동안 중합하는 제 2단계(S20);와
상형몰드와 하형몰드를 분리하여 상기 상형몰드에 압착되어 안착된 렌즈를 건조시켜 드라이 렌즈를 얻는 제 3단계(S30);와
변색염료가 도포된 실리콘 패드를 이용하여 상기 드라이 렌즈 외측부 동공부분으로 찍어 도포하는 제 4단계(S40);와
상기 변색염료가 도포된 렌즈 부분에 코팅액이 도포된 실리콘 패드를 이용하여 코팅액를 변색염료 위에 덮어씌우는 제 5단계(S50);와
코팅액이 씌워진 렌즈를 120℃의 열 오븐에 넣고 60~90분 동안 건조한 후 상기 상형몰드에서 분리하여 취득한 후 염화나트륨 0.9중량% 생리 식염수에 20~25시간 동안 수화 시킨 후 콘택트렌즈 보존액에 보관하는 제 6단계(S60);로 이루어지고,
상기 렌즈원료는 친수성 모노머 2-Hydroxyethyl methacrylate(HEMA) 96.20중량%와 Methacrylic acid(MA) 1.80 중량%, 가교제 Ethylene glycol Dimethacrylate(EGDMA) 0.4중량%, 개시제 2,5-Dimethyl-2,5-di(2-ethylhexanoylperoxy)hexane(LUPEROX 256) 0.60중량%와 UV차단제 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00중량%의 구성으로 혼합하여 30분 동안 200rpm으로 교반하는 것을 특징으로 하며,
상기 변색염료는 렌즈에 탄성을 부여하며 수분을 흡수하는 습윤성 우레탄 35중량%와 함께 습윤성 폴리머로 수분을 머금을 수 있는 PVP(Polyvinyl pirrolidone) 25중량%와 변색원료인 1,3,3-Trimethylindolinonaphthospirooxazine 10중량%를 첨가하며 패드 프린팅에 적당한 점도를 부여하는 용제로 Cyclohexanone와 Cyclopentanone 중 하나를 30중량%로 구성되는 것을 특징으로 하는 광변색 소프트 콘택트렌즈 제조 방법. In the photochromic soft contact lens manufacturing method,
A first step (S10) of adding the stirred lens material to the lower mold; and
A second step (S20) of compressing the upper mold and the lower mold and putting them in a heat oven at 120° C. for 60 to 90 minutes; And
A third step (S30) of separating the upper mold and the lower mold and drying the lens pressed and seated on the upper mold to obtain a dry lens; and
A fourth step (S40) of dipping and applying the dry lens outer pupil using a silicone pad coated with a color change dye; and
A fifth step (S50) of overlying the color-changing dye with a coating liquid using a silicone pad coated with a coating liquid on the lens portion coated with the color-changing dye; And
Put the lens covered with the coating solution in a heat oven at 120°C, dry it for 60 to 90 minutes, separate it from the upper mold, obtain it, hydrate in 0.9 wt% sodium chloride physiological saline for 20 to 25 hours, and store it in the contact lens preservation solution. It consists of step (S60);,
The lens material is a hydrophilic monomer 2-Hydroxyethyl methacrylate (HEMA) 96.20% by weight and Methacrylic acid (MA) 1.80% by weight, crosslinking agent Ethylene glycol Dimethacrylate (EGDMA) 0.4% by weight, initiator 2,5-Dimethyl-2,5-di ( 2-ethylhexanoylperoxy)hexane (LUPEROX 256) 0.60% by weight and UV blocking agent 2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate 1.00% by weight of the mixture and stirred at 200rpm for 30 minutes Characterized in that,
The color change dye provides elasticity to the lens and absorbs moisture, along with 35% by weight of wettable urethane, 25% by weight of PVP (Polyvinyl pirrolidone) that can hold moisture with a wettable polymer, and 1,3,3-Trimethylindolinonaphthospirooxazine 10, which is a color change material. A photochromic soft contact lens manufacturing method comprising 30% by weight of one of Cyclohexanone and Cyclopentanone as a solvent that adds weight% and imparts an appropriate viscosity for pad printing.
상기 변색염료가 패드 프린팅 되는 렌즈 외측부의 범위는 사람의 동공 위치와 크기에 대응될 수 있도록 직경이 2mm~10mm의 범위로 구성되되,
패드 모양에 따라 원형, 타원형, 네모, 세모, 별 모양중에서 선택적으로 프린팅 하는 것을 특징으로 하는 광변색 소프트 콘택트렌즈 제조 방법.The method of claim 1,
The range of the outer part of the lens on which the color change dye is pad-printed is composed of a range of 2mm to 10mm in diameter so as to correspond to the position and size of the pupil of a person,
A photochromic soft contact lens manufacturing method, characterized in that the printing is performed selectively among circular, oval, square, triangular, and star shapes according to the shape of the pad.
상기 변색원료인 1,3,3-Trimethylindolinonaphthospirooxazine의 성분조성을 10~50중량%로 달리하여 변색염료를 구성하는 것을 특징으로 하는 광변색 소프트 콘택트렌즈 제조 방법.The method of claim 1,
A photochromic soft contact lens manufacturing method, characterized in that the composition of the discoloration raw material 1,3,3-Trimethylindolinonaphthospirooxazine is changed to 10 to 50% by weight to constitute a color change dye.
상기 코팅액은 에틸렌옥사이드(Ethylene oxide)를 포함하는 올리고머(oligomer) 44중량%에 열가소성 우레탄(thermoplastic urethane) 28중량%와 솔벤트(solvent) 28중량%를 첨가하여 기본 혼합물을 생성하고,
상기 혼합물을 50 ~ 70℃로 가열 후 교반기를 사용하여 50 ~ 80rpm으로 28 ~ 32분간 교반한 후 상온으로 냉각하여 이루어지는 것을 특징으로 하는 광변색 소프트 콘택트렌즈 제조 방법.The method of claim 1,
The coating solution was prepared by adding 28% by weight of thermoplastic urethane and 28% by weight of a solvent to 44% by weight of an oligomer containing ethylene oxide,
The method of manufacturing a photochromic soft contact lens, characterized in that the mixture is heated to 50 to 70° C. and then stirred at 50 to 80 rpm for 28 to 32 minutes using a stirrer and then cooled to room temperature.
해당 제조방법에 따라 제조 된 것을 특징으로 하는 광변색 소프트 콘택트렌즈.
The method according to any one of claims 1 and 4 to 6,
Photochromic soft contact lens, characterized in that manufactured according to the manufacturing method.
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| KR20220159095A (en) * | 2021-05-25 | 2022-12-02 | (주)비젼사이언스 | Blue light blocking multi-porousity color contact lens manufacturing method |
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| KR102449121B1 (en) * | 2020-12-24 | 2022-09-29 | (주)비젼사이언스 | Blue light blocking contact lens manufacturing method |
| KR20220096526A (en) * | 2020-12-31 | 2022-07-07 | (주)메디오스 | Method for manufacturing color wavelength contact lenses |
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| JP2009014977A (en) * | 2007-07-04 | 2009-01-22 | Seed Co Ltd | Water-containing ophthalmic lens |
| KR101820696B1 (en) * | 2017-03-16 | 2018-01-23 | 주식회사 인터로조 | Coating Solution for Color Contact Lens and Manufacturing Method Thereof |
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| KR20020064267A (en) * | 2002-07-22 | 2002-08-07 | 조경래 | Contact lens that color changed and manufacturing process thereof |
| KR100779990B1 (en) | 2006-02-02 | 2007-11-28 | 이명규 | Photochromic Lens Mirror Coated |
| KR101123643B1 (en) * | 2010-01-13 | 2012-03-20 | 김태훈 | Contact lens comprising ultraviolet rays absorption material and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009014977A (en) * | 2007-07-04 | 2009-01-22 | Seed Co Ltd | Water-containing ophthalmic lens |
| KR101820696B1 (en) * | 2017-03-16 | 2018-01-23 | 주식회사 인터로조 | Coating Solution for Color Contact Lens and Manufacturing Method Thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20220159095A (en) * | 2021-05-25 | 2022-12-02 | (주)비젼사이언스 | Blue light blocking multi-porousity color contact lens manufacturing method |
| KR102504785B1 (en) | 2021-05-25 | 2023-02-28 | (주)비젼사이언스 | Blue light blocking multi-porousity color contact lens manufacturing method |
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