KR102149838B1 - Method of manufacture for contact lenses blocking blue light - Google Patents

Abstract

The present invention relates to a method for manufacturing a blue light blocking contact lens by forming the contact lens to be laminated while a blue light blocking layer is included therein, the method comprising: a first step for supplying a blue light blocking layer-forming material to the upper molding frame; a second step for injecting a contact lens molding material into the lower molding frame; a third step for forming a blue light blocking contact lens (L) by combining the upper and lower molding frames, heating and pressing the contact lenses to be laminated while the blue light blocking layer is included in the contact lenses; and the fourth step for separating the blue light blocking contact lens (L) by opening the upper and lower molding frames. A method for manufacturing a blue light blocking contact lens according to the present invention, has a simple manufacturing process, and in which the affinity between a blue light blocking layer and a contact lens is good, so that the blue light blocking layer is stably formed thereby exhibiting a uniform blocking effect, and thus having an effect of keeping the lifespan of the blue light blocking layer in the long term.

Description

Method of manufacture for contact lenses blocking blue light

The present invention relates to a method of manufacturing a blue light blocking contact lens, and more particularly, to a method of manufacturing a blue light blocking contact lens by molding a blue light blocking layer of the contact lens to be included and stacked inside the contact lens.

In general, green and red parts of visible light, and electromagnetic waves with long wavelengths such as infrared, microwave, and radio waves are not significantly harmful to the human eye, but blue light with a wavelength of 380 to 500 nm within visible light. (blue light) is very harmful to the human body, especially the eyes.

The blue light (blue light) has a higher refractive index than other visible light bands, so the image is formed in front of the network of the eye, so the eye is not recognized as an accurate image. Focal length exercise is attempted, which causes problems such as eye fatigue, dry eye syndrome, decreased vision, and shoulder and back pain.

In the displays of TVs, computer monitors, smartphones, tablet PCs, and portable game consoles, which are widely used in recent years, CCFL (cold cathode fluorescent lamps) or LEDs (light emitting diodes) have bright light as a light source to increase resolution. ), and these CCFLs and LEDs contain as much blue light instead of bright light, so modern people's vision is inevitably lowered compared to the past, so to protect vision, glasses that block blue light It is desirable to wear it.

As a blue light blocking technology for eyesight protection, for example, in Patent Document 1, blue light is dispersed and diffused in 100 parts by weight of a monomer of a plastic lens to reduce the lens transmittance of blue light by dispersing and diffusing blue light in the region of 380 nm to 500 nm. A blue light-emitting agent consisting of a compound of thiophene and benzene to block the transmission of 0.01 ~ 0.05 parts by weight, and a 2-(2-) having a function of preventing the lens from being deformed by ultraviolet rays while having a blocking function by absorption of ultraviolet rays. 0.18 parts by weight of UV-5411 sunscreen of hydroxy-5-t-octylphenyl)benzotriazole, 0.44 parts by weight of the first pigment called BL-1, which gives a blue light when the dose is increased, and the lens becomes red when the dose is increased. It discloses a blue light blocking lens characterized in that 0.16 parts by weight of a second pigment called BL-2 that emits light and 3 parts by weight of a polymerization initiator called IPP that reacts a monomer into a polymer are mixed. Patent Document 2 discloses an acrylic discoloration lens. A method for manufacturing a sunglasses lens for blocking blue light comprising a lens substrate manufacturing step of manufacturing a substrate and a coloring step of immersing the acrylic color-changing lens substrate in a dye, wherein the lens substrate manufacturing step includes heat polymerization at 75 to 110°C. It includes a polymerization step, wherein the coloring step is sequentially immersed in 3 to 5 kinds of colored dyes having different color wavelengths, but the colored dye is a monochromatic colored dye in which two or more dyes are not mixed, and an orange dye is used as a blue light blocking agent. Disclosed is a method of manufacturing a sunglasses lens for blocking blue light, characterized in that immersion is performed in the first to second order for each colored color.

In addition, in Patent Document 3, the first step of dipping the blue light blocking dye into the shape of a pupil on the silicone pad, the second step of putting the stirred lens material into the lower mold, and the upper mold and the lower mold are compressed into a heat oven at 120°C. The third step of adding and polymerizing for 60 to 90 minutes, and the fourth step of separating the upper mold and the lower mold to obtain a contact lens, hydrating in sodium chloride 0.9% physiological saline for 20 to 25 hours, and then storing it in the contact lens preservative solution Disclosed is a method of manufacturing a blue light blocking contact lens composed of, and the prior arts manufacture a blue light blocking contact lens by mixing a blocking agent with a lens material or coating a complexing agent on the surface of the lens.

The inventor of the present application completed the present invention by improving the manufacturing process of the blue light blocking contact lens by forming the blue light blocking layer to be laminated to be included in the contact lens.

KR 10-1540114 B KR 10-1877212 B KR 10-2008138 B

The problem to be solved in the present invention relates to the provision of a method for manufacturing a blue light blocking contact lens, and more particularly, a method of manufacturing a blue light blocking contact lens by molding a blue light blocking layer to be laminated while being included in the contact lens. It is intended to provide.

The method of manufacturing a blue light blocking contact lens as a solution to the subject of the present invention is a). A first step of supplying a blue light blocking layer forming material containing a blue light blocking agent to an upper molding mold to form a blue light blocking layer of a contact lens, and b) injecting a contact lens molding material into the lower molding mold. The second step, c). A third step of forming a blue light blocking contact lens by inverting the upper molding frame, and forming a blue light blocking contact lens by combining it with the lower molding frame, heating, and compressing the contact lens to be laminated with the blue light blocking layer included therein, and d), And a fourth process of separating the blue light blocking contact lens by opening the upper and lower molding frames.

A method of manufacturing a blue light blocking contact lens according to an embodiment of the present invention a). In order to form the blue light blocking layer of the contact lens, the blue light blocking layer forming material containing 0.5 to 15% by weight of the blue light blocking agent is supplied to the upper molding frame (1) based on the total weight of the blue light blocking layer forming material. A first step, b) a second step of injecting a contact lens molding material containing 2-hydroxyethyl methacrylate (2-HEMA) as a polymerizable monomer into the lower molding mold 2, c). After inverting the upper mold (1), it is combined with the lower mold (2), heated at 100 to 130°C for 30 to 60 minutes, and pressurized to be laminated while the blue light blocking layer is included in the contact lens. The third step of forming the blue light blocking contact lens (L) and d). And a fourth process of separating the blue light blocking contact lens L by opening the upper and lower molding frames 1 and 2.

The blue light blocking layer forming material of the present invention is 2,2'4,4'-tetrahydroxybenzophenone as a blue light blocking agent, 2-hydroxyethyl methacrylate (2-HEMA) as a polymerizable monomer, and co-monomer , An initiator and a solvent, etc., and a colorant may be blended if necessary.

The contact lens molding material of the present invention contains, as a main component, 2-hydroxyethyl methacrylate (2-HEMA), which is a polymerizable monomer, and is composed of a crosslinking agent, an initiator, and an accelerator.

In the method of manufacturing a blue light blocking contact lens according to the present invention, the blue light blocking layer forming material and the contact lens molding material both commonly select 2-hydroxyethyl methacrylate (2-HEMA), which is a polymerizable monomer. During the molding process, the blue light blocking layer and the contact lens have good affinity, so that the blue light blocking layer is incorporated into the contact lens and is stably formed into a stacked structure.

The manufacturing method of the blue light blocking contact lens of the present invention has a simple manufacturing process, and since the blue light blocking layer and the type contact lens are made of the same molding material, the blue light blocking layer is included inside the contact lens and is stable in a stacked structure. It has an effect of maintaining the life of the blue light blocking layer for a long period of time, and has the effect of easily adjusting the concentration of the blue light blocking agent.

1 is a schematic view showing a manufacturing process of a blue light blocking contact lens according to the present invention
2 is a schematic view showing a blue light blocking contact lens according to the present invention

Hereinafter, the present invention will be specifically described with reference to specific details for carrying out the present invention, but the present invention is not limited by the following description.

1 is a view schematically showing the manufacturing process of the blue light blocking contact lens (L) according to the present invention, Figure 2 is a view schematically showing the blue light blocking contact lens according to the present invention, Figs. Referring to the method of manufacturing the blue light blocking contact lens of the present invention will be described in more detail,

1 and 2, in the blue light blocking contact lens L of the present invention, a blue light blocking layer A is disposed at the center of the contact lens body B and the inner side of the contact lens. It consists of a stacked structure while being included.

And as shown in Figure 1, the method of manufacturing the blue light blocking contact lens of the present invention is a). Blocking blue light containing 0.5 to 15% by weight of a blue light blocking agent based on the total weight of the blue light blocking layer forming material (A1) on the upper molding frame (1) to form the blue light blocking layer (A) of the contact lens The first step of supplying the layer forming material (A1), and b) a contact lens molding material (B1) containing 2-hydroxyethyl methacrylate (2-HEMA) as a polymerizable monomer in the lower molding mold (2) A second step of injecting and c). After inverting the upper mold (1), it is combined with the lower mold (2), heated and pressed at 100 to 130°C for 30 to 60 minutes, and a blue light blocking layer is included inside the contact lens (B). The third step of forming the blue light blocking contact lens L in a stacked structure and d). It consists of including a fourth step of separating the blue light blocking contact lens (L) by opening the upper and lower molding frames (1, 2).

The first process according to the present invention comprises a process of supplying a blue light blocking layer forming material (A1) to the upper surface of the upper molding mold (1) to form the blue light blocking layer (A) of the contact lens.

The blue light blocking layer (A) is formed by a screen printing method on the upper frame so as to be located in the center of the lens, and considering that the pupil size of the eye is 3 to 4 mm, the coloration diameter is 7 mm or more and the thickness is 10 to 20. A blue light blocking layer (A) is formed about µm.

The blue light blocking layer forming material (A1) is 2,2'4,4'-tetrahydroxybenzophenone as a blue light blocking agent, and 2-hydroxyethyl methacrylate (2-HEMA) as a polymerizable monomer as a binder component It is composed of an auxiliary monomer, an initiator, and a solvent as the main component.

The blue light blocking agent, 2,2'4,4'-tetrahydroxybenzophenone, is a widely known material on the market and has a characteristic of blocking blue light in the 380 nm to 500 nm region, and a blocking layer forming material ( It is preferable to contain 0.5 to 15% by weight based on the total weight of A).

In addition, the blue light blocking layer forming material (A1) may contain a dye, and as a dye, DNC Yellow 10 (CAS NO:8004-92-0), which is widely marketed, is preferable.

The 2-hydroxyethyl methacrylate (2-HEMA) is a hydrophilic polymerizable monomer and is a binder component of the blue light blocking layer forming material (A1), based on the total weight of the blue light blocking layer forming material (A1). It is preferable to contain ~ 40% by weight.

The co-monomer is selected from at least one component selected from N-vinylpyrrolidone, methyl methacrylate, glycidyl methacrylate and methacrylic acid, and 0.5 based on the total weight of the barrier layer forming material (A1). It contains ~ 1% by weight.

The initiators are benzoylperoxide, cumylperoxide, butylperoxide, butylperoxybenzoate, 2,2'-azobis(2,4-dimethylpentanenitrile) and 2,2'-azobis(2-methylpropane). Nitrile) is selected from at least one component, and preferably contains 1 to 1.5% by weight based on the total weight of the blue light blocking layer forming material (A1).

As the solvent, a single or mixed solvent is composed of 2-ethoxyethanol and N-butyl acetate, and the solvent is a blue light blocking layer forming material according to the mixing ratio of the blue light blocking agent, binder component, auxiliary monomer, initiator, etc. It is formulated within a range showing a viscosity suitable for supplying A1) to the upper surface of the upper mold 1.

The second process according to the present invention is a process of injecting (supplying) a contact lens molding material (B1) into the lower molding mold (2) for forming a contact lens, and the contact lens molding material (B1) into the lower molding mold (2). The injection (supply) amount of is injected (supplied) so as to be suitable for molding according to the standard of a conventional contact lens.In general, contact lenses have a total diameter of 13.8 ~ 15.0 mm, and the thickness of the optical zone of the lens is 5 ~ It is manufactured with 7㎜ and a radius of curvature of 8.4 ~ 8.8㎜.

The contact lens molding material (B1) is composed of 2-hydroxyethyl methacrylate (2-HEMA), a crosslinking agent, an initiator, and an accelerator, and a contact lens molding material known in the art may be selected. .

The initiator is as listed in the blue light blocking layer forming material (A1), and the crosslinking agent is ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, trimethylolpropane trimethacrylate, and arylmethacrylate. One or more components are selected from acrylates.

2-hydroxyethyl methacrylate (2-HEMA), a hydrophilic polymerizable monomer composed of the contact lens molding material (B1), contains 80 to 89% by weight based on the total weight of the contact lens molding material (B1) And, the crosslinking agent and initiator are each composed of 0.2 to 0.5% by weight

In addition, the contact lens molding material (B1) may further contain a polymerizable monomer, 2-methacrylooxyethylphosphorylcholine, and 1 to 10% by weight based on the total weight of the contact lens molding material (B1). It is desirable

The 2-methacrylooxyethylphosphorylcholine is a polymerizable material and is additionally formulated in the contact lens molding material (B1) to improve the wettability of the contact lens, thereby improving the fit of the contact lens.

The third process according to the present invention is a structure in which the upper mold 1 in the first process is inverted and then combined with the lower mold 2 to be stacked to include a blue light blocking layer inside the contact lens. It consists of a process of molding the light blocking contact lens (L).

In the third process, the upper molding mold 1 for forming a contact lens in which the blue light blocking layer forming material (A1) is applied on the upper surface is inverted, and then the upper part for forming the contact lens into which the contact lens molding material (B1) is injected. It consists of combining with the molding mold (2) and heating and pressing at 100 to 130 °C for 30 to 60 minutes.

The blue light blocking layer forming material (A1) and the contact lens forming material (B1) are polymerized and cured in the process of combining the upper and lower molding molds for contact lens molding, heating, and pressing, and the blue light blocking layer (A) is contacted. It is incorporated into the interior of the lens B and has a laminated structure, and is molded into a blue light blocking contact lens L.

The blue light blocking contact lens (L) manufactured according to the manufacturing method of the present invention is mainly composed of 2-hydroxyethyl methacrylate (2-HEMA) in which the blue light blocking layer (A) and the contact lens (B) are the same component. The blue light blocking layer (A) is formed stably and has a uniform blocking effect because the blue light blocking layer (A) is formed with good affinity with the lens. In particular, the blue light blocking layer (A) is a contact lens. Since it is made of a stacked structure included in the interior of (B), the life of the blocking layer (A) is maintained for a long time.

Hereinafter, a method of manufacturing the blue light blocking contact lens L of the present invention will be described in more detail through <Example> and <Test Example>.

<Example 1> and <Example 2>

The blue light blocking layer forming material (A1) and the contact lens forming material (B1) were prepared by uniformly mixing the components according to the composition and ratio shown in [Table 1] below, and then the blue light blocking contact lens manufacturing method of the present invention The lens was molded and processed according to the following: The total diameter of the lens is 14.0 mm, the thickness of the optical zone is 6 mm, the diameter of the blue light blocking layer is 7 mm, the thickness of the blue light blocking layer is 20 microns, and the radius of curvature is 8.6 mm. A light blocking contact lens (L) was produced.

ingredient Barrier layer forming material (A1) (wt%) Lens molding material (B1) (wt%) Example 1 Example 2 Example 1 Example 2 2,2'4,4'-tetrahydroxybenzophenone One 10 - - 2-hydroxyethyl methacrylate 35 32 89 89 Ethyleneglycol dimethacrylate 0.7 0.7 2,2'-Azobis(2-methylpropionitrile) 0.3 0.3 Methyl methacrylate 0.01 0.01 Glycidyl methacrylate 0.7 0.7 Methacrylic acid 0.09 0.09 Benzoyl Peroxide 1.2 1.2 2-Ethoxyethanol 52 47.5 N-Butyl acetate 10 8.5 2-methacryloyloxyethylphospholinecholine - - 10 10

<Test Example>

Blocking rates of blue light in the region of 380 nm to 500 nm, the region of 320 to 400 nm, UVA and UVB of the 290 to 320 nm region with respect to the blue light blocking contact lenses (L) prepared in <Example 1> and <Example 2> (%) was tested and the results are shown in Table 2 since then.

An absorption spectrum test is performed with a UV-VIS spectrophotometer to measure the transmittance of the sample to a wavelength. At this time, the blue light blocking contact lens is placed in the center jig, the transmittance for the wavelength is calculated, and the sum of parameters is divided by wavelength. That is, 100- (arithmetic measurement value) = cut-off rate is estimated on the arithmetic measurement value.

division Blocker
Content (wt%)) 380nm ~ 500nm area
Blue light blocking rate (%) 320~400nm area
UVA blocking rate (%) 290~320nm area
UVB blocking rate (%) Example 1 One 95.9 99.7 99.9 Example 2 10 99.4 99.9 99.9

As shown in [Table 2], the blue light blocking rate of the contact lens with the blue light blocking layer of the present invention is excellent. In the present invention, the blocking layer and the lens are made of the same molding material, so that the blocking layer has good mutual affinity It is formed stably and has the effect of maintaining the life of the blocking layer for a long period of time, and has the effect of easily adjusting the concentration of the blue light blocking agent.

L: blue light blocking contact lens, A, A1: blue light blocking layer and blocking layer forming material, B, B1; Contact lenses and lens molding materials, 1, 2; Upper and lower molds for contact lens molding

Claims (4)

a). 2-hydroxyethyl methacrylate, a hydrophilic polymerizable monomer, based on the total weight of the blue light blocking layer forming material (A1) on the upper molding frame (1) to form the blue light blocking layer (A) of the contact lens (2-HEMA) 30 to 40% by weight, containing 0.5 to 15% by weight of 2,2'4,4'-tetrahydroxybenzophenone, which is a blue light blocking agent, and blocking blue light further comprising an auxiliary monomer, an initiator and a solvent A first step of supplying a layer forming material (A1), and
b) 2-hydroxyethyl methacrylate (2-hydroxyethyl methacrylate), which is the same component as the binder component of the blue light blocking layer forming material (A1), based on the total weight of the contact lens molding material (B1) in the lower molding frame (2). HEMA) a second step of injecting a contact lens molding material (B1) containing 80 to 89% by weight and 1 to 10% by weight of 2-methacrylooxyethylphosphorylcholine, and further comprising a crosslinking agent and an initiator,
c). After inverting the upper mold (1), it is combined with the lower mold (2), heated and pressed at 100 to 130 °C for 30 to 60 minutes, and then laminated while the blue light blocking layer is included in the contact lens. A third process of molding the blue light blocking contact lens (L) and
d). And a fourth step of separating the blue light blocking contact lens (L) by opening the upper and lower molding frames (1, 2). delete The method according to claim 1, wherein the blue light blocking layer forming material (A1) in the first step is at least one component selected from N-vinylpyrrolidone, methyl methacrylate, glycidyl methacrylate and methacrylic acid as an auxiliary monomer. Blue light blocking contact lens manufacturing method, characterized in that selected. The method of claim 3, Initiators of the first and second steps are benzoylperoxide, cumylferoxide, butylperoxide, butylperoxybenzoate, 2,2'-azobis (2,4-dimethylpentanenitrile) and 2,2'- At least one component is selected from azobis (2-methylpropanenitrile), and the crosslinking agent in the second process is ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, trimethylolpropane trimethacrylate, and arylmethacryl At least one component is selected from the rate, and the solvent of the first step is a method of manufacturing a blue light blocking contact lens, wherein one or more components are selected from 2-ethoxyethanol and N-butyl acetate.

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