KR102113296B1 - 치료용 생물학적 물질 및 소분자를 보관 및 전달하기 위한 크로마토그래피 매질 - Google Patents

치료용 생물학적 물질 및 소분자를 보관 및 전달하기 위한 크로마토그래피 매질 Download PDF

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KR102113296B1
KR102113296B1 KR1020147022518A KR20147022518A KR102113296B1 KR 102113296 B1 KR102113296 B1 KR 102113296B1 KR 1020147022518 A KR1020147022518 A KR 1020147022518A KR 20147022518 A KR20147022518 A KR 20147022518A KR 102113296 B1 KR102113296 B1 KR 102113296B1
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KR20140117529A (ko
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존 에이. 치코스키
챨스 에이치. 허니맨
몰리 에스. 맥로린
암로 라그헵
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나트릭스 세퍼레이션즈, 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
KR1020147022518A 2012-01-19 2013-01-18 치료용 생물학적 물질 및 소분자를 보관 및 전달하기 위한 크로마토그래피 매질 Active KR102113296B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261588312P 2012-01-19 2012-01-19
US61/588,312 2012-01-19
PCT/US2013/022057 WO2013109825A1 (en) 2012-01-19 2013-01-18 Chromatographic media for storage and delivery of therapeutic biologics and small molecules

Publications (2)

Publication Number Publication Date
KR20140117529A KR20140117529A (ko) 2014-10-07
KR102113296B1 true KR102113296B1 (ko) 2020-06-02

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KR1020147022518A Active KR102113296B1 (ko) 2012-01-19 2013-01-18 치료용 생물학적 물질 및 소분자를 보관 및 전달하기 위한 크로마토그래피 매질

Country Status (10)

Country Link
US (2) US20130189322A1 (https=)
EP (1) EP2804634B1 (https=)
JP (2) JP6552822B2 (https=)
KR (1) KR102113296B1 (https=)
AU (1) AU2013209620B2 (https=)
CA (2) CA3124806C (https=)
DK (1) DK2804634T3 (https=)
ES (1) ES2750211T3 (https=)
IN (1) IN2014DN06817A (https=)
WO (1) WO2013109825A1 (https=)

Families Citing this family (8)

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Publication number Priority date Publication date Assignee Title
RU2015114330A (ru) 2012-09-17 2016-11-10 У.Р. Грейс Энд Ко.-Конн. Хроматографические среды и устройства
WO2015013542A1 (en) 2013-07-25 2015-01-29 Bio-Rad Laboratories, Inc. Enhanced functionality and delivery of a protein from a porous substrate
FR3012978A1 (fr) * 2013-11-12 2015-05-15 Biocarecell Filtre biocompatible et procede de fabrication d'un filtre biocompatible.
US11229896B2 (en) 2014-01-16 2022-01-25 W.R. Grace & Co.—Conn. Affinity chromatography media and chromatography devices
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 官能化担体材料並びに官能化担体材料を作製及び使用する方法
IS3008B (is) * 2014-05-14 2018-12-15 Calor ehf Stöðgandi lausnir fyrir prótín og peptíð
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
EP3781192A1 (en) * 2018-04-16 2021-02-24 Merck Patent GmbH Additives for protein formulations to improve thermal stability

Citations (2)

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US20030178210A1 (en) 2002-03-19 2003-09-25 Deere & Company, A Delaware Corporation Bearing guard for a ground-working implement
US20100178210A1 (en) 2004-05-24 2010-07-15 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form

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US5059654A (en) * 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
ATE68524T1 (de) * 1985-07-09 1991-11-15 Quadrant Bioresources Ltd Beschuetzung von proteinen und aehnlichem.
US5492821A (en) * 1990-11-14 1996-02-20 Cargill, Inc. Stabilized polyacrylic saccharide protein conjugates
US5159049A (en) * 1991-04-22 1992-10-27 Allen Robert C Method for stabilizing polyacrylamide gels
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US6284282B1 (en) * 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
SE9904475D0 (sv) * 1999-12-08 1999-12-08 Artursson Nucleic acid delivery system
US6896894B2 (en) * 2001-10-30 2005-05-24 Battelle Memorial Institute Proteins stabilized with polysaccharide gums
EP1471891A4 (en) * 2002-02-08 2007-04-11 Alkermes Inc POLYMER BASED COMPOSITIONS WITH DELAYED RELEASE
US20040137004A1 (en) * 2002-03-19 2004-07-15 Glenn Gregory M Patch for transcutaneous immunization
EP2143482A1 (en) 2003-02-19 2010-01-13 Natrix Separations Inc. Composite materials comprising supported porous gels
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
AU2005231532B2 (en) 2004-04-08 2010-01-07 Merck Millipore Ltd. Membrane stacks
US8133840B2 (en) * 2004-06-07 2012-03-13 Natrix Separations Inc. Stable composite material comprising supported porous gels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030178210A1 (en) 2002-03-19 2003-09-25 Deere & Company, A Delaware Corporation Bearing guard for a ground-working implement
US20100178210A1 (en) 2004-05-24 2010-07-15 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form

Also Published As

Publication number Publication date
CA2861932C (en) 2021-09-14
EP2804634A1 (en) 2014-11-26
ES2750211T3 (es) 2020-03-25
JP2015504092A (ja) 2015-02-05
IN2014DN06817A (https=) 2015-05-22
KR20140117529A (ko) 2014-10-07
US20130189322A1 (en) 2013-07-25
AU2013209620A1 (en) 2014-08-28
EP2804634B1 (en) 2019-08-28
CA2861932A1 (en) 2013-07-27
US20200069602A1 (en) 2020-03-05
EP2804634A4 (en) 2015-07-22
CA3124806C (en) 2023-09-26
JP6552822B2 (ja) 2019-07-31
JP2019011341A (ja) 2019-01-24
DK2804634T3 (da) 2019-11-04
CA3124806A1 (en) 2013-07-27
AU2013209620B2 (en) 2017-06-15
WO2013109825A1 (en) 2013-07-25

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