KR102110794B1 - 인간의 신경교종을 치료하기 위한 모노아마이드 옥시다아제(Monoamide oxidase,MAO) 타겟팅/시커(seeker) 부분(moiety)을 포함하는 조성물 - Google Patents

인간의 신경교종을 치료하기 위한 모노아마이드 옥시다아제(Monoamide oxidase,MAO) 타겟팅/시커(seeker) 부분(moiety)을 포함하는 조성물 Download PDF

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KR102110794B1
KR102110794B1 KR1020147014835A KR20147014835A KR102110794B1 KR 102110794 B1 KR102110794 B1 KR 102110794B1 KR 1020147014835 A KR1020147014835 A KR 1020147014835A KR 20147014835 A KR20147014835 A KR 20147014835A KR 102110794 B1 KR102110794 B1 KR 102110794B1
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compound
mao
delete delete
cancer
treatment
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KR20140128943A (ko
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데이비드 에스. 바스킨
마틴 알룬 샤프
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더 메서디스트 하스피틀 리서치 인스티튜트
데이비드 에스. 바스킨
마틴 알룬 샤프
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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  • Nitrogen Condensed Heterocyclic Rings (AREA)
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KR1020147014835A 2011-10-31 2012-10-31 인간의 신경교종을 치료하기 위한 모노아마이드 옥시다아제(Monoamide oxidase,MAO) 타겟팅/시커(seeker) 부분(moiety)을 포함하는 조성물 Expired - Fee Related KR102110794B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161553854P 2011-10-31 2011-10-31
US61/553,854 2011-10-31
PCT/US2012/062850 WO2013151584A1 (en) 2011-10-31 2012-10-31 Compound comprising a mao targeting/ seeker moiety for treating human gliomas

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KR20140128943A KR20140128943A (ko) 2014-11-06
KR102110794B1 true KR102110794B1 (ko) 2020-05-15

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KR1020147014835A Expired - Fee Related KR102110794B1 (ko) 2011-10-31 2012-10-31 인간의 신경교종을 치료하기 위한 모노아마이드 옥시다아제(Monoamide oxidase,MAO) 타겟팅/시커(seeker) 부분(moiety)을 포함하는 조성물

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US (1) US10555936B2 (https=)
EP (2) EP2804604A1 (https=)
JP (1) JP6118808B2 (https=)
KR (1) KR102110794B1 (https=)
CN (1) CN104136026B (https=)
AU (1) AU2012376221A1 (https=)
CA (1) CA2887928A1 (https=)
HK (1) HK1204547A1 (https=)
WO (1) WO2013151584A1 (https=)

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CN104136026B (zh) 2011-10-31 2018-03-02 卫理公会医院研究所 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物
CN104710433B (zh) * 2014-01-23 2016-08-17 南京友怡医药科技有限公司 苯丁酸氮芥衍生物、制备方法及应用
WO2015153516A1 (en) * 2014-04-04 2015-10-08 University Of Florida Research Foundation Hdac inhibitor compounds and methods of treatment
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029333A1 (en) 1993-06-07 1994-12-22 The Wellcome Foundation Limited Immunoreactive reagents employing monoamine oxidase

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US4913891A (en) * 1986-04-17 1990-04-03 The United States Of America As Represented By The United States Department Of Energy Positron emitter labeled enzyme inhibitors
US5466468A (en) 1990-04-03 1995-11-14 Ciba-Geigy Corporation Parenterally administrable liposome formulation comprising synthetic lipids
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
IE80468B1 (en) 1995-04-04 1998-07-29 Elan Corp Plc Controlled release biodegradable nanoparticles containing insulin
US5612329A (en) 1995-06-05 1997-03-18 University Of Maryland At Baltimore Diaziridinylpolyamine anti-cancer agents
WO1998022110A1 (en) * 1996-11-20 1998-05-28 Virginia Tech Intellectual Properties, Inc. Prodrugs for the selective inhibition of monoamine oxidase-b
KR20010102486A (ko) 1999-03-03 2001-11-15 데이비드 엠 모이어 알케닐- 및 알키닐-함유 메탈로프로테아제 저해제
WO2002038628A2 (en) 2000-11-07 2002-05-16 Symyx Technologies, Inc. Substituted pyridyl amine ligands, complexes and catalysts therefrom; processes for producing polyolefins therewith
US6946479B2 (en) 2002-11-09 2005-09-20 The Procter & Gamble Company N-sulfonyl-4-methyleneamino-3-hydroxy-2-pyridones
US7943586B2 (en) 2003-06-09 2011-05-17 The Trustees Of The University Of Pennsylvania Antineoplastic agents targeted via glut transporters
MXPA06013165A (es) * 2004-05-14 2007-02-13 Pfizer Prod Inc Derivados de pirimidina para el tratamiento de crecimiento de celulas anormal.
US7091205B2 (en) 2004-10-08 2006-08-15 Yu Show Fu Use of tetramethylpyrazine in the treatment of brain tumor
GB0513297D0 (en) 2005-06-29 2005-08-03 Glaxo Group Ltd Novel compounds
US20070275944A1 (en) 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
AR070317A1 (es) * 2008-02-06 2010-03-31 Osi Pharm Inc Furo (3,2-c) piridina y tieno (3,2-c) piridinas
PE20091561A1 (es) * 2008-02-29 2009-10-30 Array Biopharma Inc Compuestos inhibidores de raf y metodos para su uso
EP2141163A1 (de) * 2008-07-02 2010-01-06 Bayer Schering Pharma AG Substituierte Thiazolidinone, deren Herstellung und Verwendung als Arzneimittel
EP3613729A1 (en) * 2009-06-10 2020-02-26 Chugai Seiyaku Kabushiki Kaisha Tetracyclic compounds
EP2480531B1 (en) * 2009-09-21 2014-11-05 ChemoCentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r (chemr23) modulators
CN104136026B (zh) 2011-10-31 2018-03-02 卫理公会医院研究所 包含mao靶向/探寻器部分的人神经胶质瘤治疗用化合物

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1994029333A1 (en) 1993-06-07 1994-12-22 The Wellcome Foundation Limited Immunoreactive reagents employing monoamine oxidase

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Publication number Publication date
EP3815685A3 (en) 2021-10-13
KR20140128943A (ko) 2014-11-06
HK1204547A1 (en) 2015-11-27
CA2887928A1 (en) 2013-10-10
EP3815685A2 (en) 2021-05-05
WO2013151584A1 (en) 2013-10-10
EP2804604A1 (en) 2014-11-26
CN104136026A (zh) 2014-11-05
JP2014534227A (ja) 2014-12-18
AU2012376221A1 (en) 2014-06-19
US20140323513A1 (en) 2014-10-30
CN104136026B (zh) 2018-03-02
JP6118808B2 (ja) 2017-04-19
US10555936B2 (en) 2020-02-11

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