KR102039494B1 - 세포 배양 배지 및 방법 - Google Patents

세포 배양 배지 및 방법 Download PDF

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KR102039494B1
KR102039494B1 KR1020147019999A KR20147019999A KR102039494B1 KR 102039494 B1 KR102039494 B1 KR 102039494B1 KR 1020147019999 A KR1020147019999 A KR 1020147019999A KR 20147019999 A KR20147019999 A KR 20147019999A KR 102039494 B1 KR102039494 B1 KR 102039494B1
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feed
cell culture
poly
beads
cells
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KR20140113693A (ko
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리차드 파이크
숀 바렛
주 지앙
데이비드 주드
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라이프 테크놀로지스 코포레이션
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/24—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00 characterised by the choice of material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2009/00—Layered products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00—Cells for large scale production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/72—Chitin, chitosan
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/76—Agarose, agar-agar
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/78—Cellulose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/80—Hyaluronan

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020147019999A 2011-12-22 2012-12-21 세포 배양 배지 및 방법 Active KR102039494B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579432P 2011-12-22 2011-12-22
US61/579,432 2011-12-22
PCT/US2012/071411 WO2013096858A1 (en) 2011-12-22 2012-12-21 Cell culture media and methods

Publications (2)

Publication Number Publication Date
KR20140113693A KR20140113693A (ko) 2014-09-24
KR102039494B1 true KR102039494B1 (ko) 2019-11-01

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Country Link
US (4) US9410118B2 (https=)
EP (2) EP3702442B1 (https=)
JP (4) JP6216327B2 (https=)
KR (1) KR102039494B1 (https=)
CN (2) CN104080905B (https=)
WO (1) WO2013096858A1 (https=)

Cited By (1)

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WO2024096506A1 (ko) * 2022-10-31 2024-05-10 삼성바이오에피스 주식회사 고농도 액체 배지 제조 방법

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KR102007997B1 (ko) * 2011-02-07 2019-08-07 라이프 테크놀로지스 코포레이션 감수성 화합물을 안정화시키는 조성물 및 방법
CN104080905B (zh) * 2011-12-22 2016-11-16 生命技术公司 细胞培养基和方法
CA2917745A1 (en) * 2013-07-11 2015-01-15 Merck Patent Gmbh A dry cell culture medium comprising a polymer-embedded component
CN112662611B (zh) * 2014-01-23 2024-10-29 日产化学工业株式会社 培养基组合物
US20150275167A1 (en) * 2014-03-28 2015-10-01 Corning Incorporated Composition and method for cell culture sustained release
RU2016144057A (ru) * 2014-04-10 2018-05-15 Байер Хелскеа Ллк Смешанный состав порошка среды и способ получения жидкой среды для культуры клеток
US10900021B2 (en) * 2015-06-08 2021-01-26 Corning Incorporated Drying formulation for hydrogel microcarriers
EP3377645B1 (en) * 2015-11-20 2023-10-04 Qiagen GmbH Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
KR20180091923A (ko) * 2015-12-17 2018-08-16 라이프 테크놀로지스 코포레이션 세포 배양에 이용되는 펠릿 및 이의 제조 방법
RU2762292C2 (ru) * 2015-12-30 2021-12-17 Лайф Текнолоджиз Корпорейшн Слоистые частицы клеточной культуры и способы их получения
CN106222236A (zh) * 2016-07-27 2016-12-14 郑州点石生物技术有限公司 血液中微生物检测试剂及其制备方法
CN109395095B (zh) * 2017-09-18 2021-09-24 武汉原生原代生物医药科技有限公司 体内用生物膜及其制备方法和用途
CN112469814A (zh) * 2018-07-27 2021-03-09 味之素株式会社 动物细胞的悬浮培养用添加物、悬浮培养用培养基和悬浮培养方法
EP4182438A1 (en) * 2020-07-14 2023-05-24 Corning Incorporated Rapidly dissolving cell culture media powder and methods of making the same
CN111849879A (zh) * 2020-08-07 2020-10-30 张娇 一种细胞培养基及细胞培养方法
CN112553116A (zh) * 2020-12-23 2021-03-26 邢箫 一种益生菌培养基及益生菌制剂

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KR102007997B1 (ko) * 2011-02-07 2019-08-07 라이프 테크놀로지스 코포레이션 감수성 화합물을 안정화시키는 조성물 및 방법
CN104080905B (zh) * 2011-12-22 2016-11-16 生命技术公司 细胞培养基和方法

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WO2003005989A2 (en) * 2001-07-11 2003-01-23 Apr Applied Pharma Research Sa Granulates containing liposoluble substances and a process for the preparation thereof
WO2003086104A1 (en) * 2002-04-11 2003-10-23 Ocean Nutrition Canada Ltd. Encapsulated agglomeration of microcapsules and method for the preparation thereof

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Publication number Priority date Publication date Assignee Title
WO2024096506A1 (ko) * 2022-10-31 2024-05-10 삼성바이오에피스 주식회사 고농도 액체 배지 제조 방법

Also Published As

Publication number Publication date
CN106635949B (zh) 2020-05-19
US20150064785A1 (en) 2015-03-05
EP2794853B1 (en) 2020-04-22
WO2013096858A1 (en) 2013-06-27
EP3702442B1 (en) 2025-06-25
KR20140113693A (ko) 2014-09-24
US12203095B2 (en) 2025-01-21
US10066200B2 (en) 2018-09-04
CN104080905A (zh) 2014-10-01
JP2015503329A (ja) 2015-02-02
US20200332250A1 (en) 2020-10-22
CN104080905B (zh) 2016-11-16
JP6457041B2 (ja) 2019-01-23
JP2018038404A (ja) 2018-03-15
US20180346872A1 (en) 2018-12-06
US20160376548A1 (en) 2016-12-29
JP2021087446A (ja) 2021-06-10
US9410118B2 (en) 2016-08-09
EP3702442A1 (en) 2020-09-02
JP6216327B2 (ja) 2017-10-18
CN106635949A (zh) 2017-05-10
JP7217765B2 (ja) 2023-02-03
JP6843824B2 (ja) 2021-03-17
EP2794853A1 (en) 2014-10-29
JP2019062901A (ja) 2019-04-25

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