KR102032969B1 - Sun screen composition comprising Panax ginseng extract and Green tea extract - Google Patents

Abstract

The present invention relates to a composition for sun protection, and more particularly, to a composition having excellent ginseng extract and green tea extract as an active ingredient, the effect of blocking the ultraviolet rays and preventing skin damage by ultraviolet rays.

Description

Sunscreen composition comprising Panax ginseng extract and Green tea extract}

The present invention relates to a composition for sunscreen, and more particularly to a composition containing the ginseng extract and green tea extract as an active ingredient and excellent in the sunscreen effect and the skin damage prevention effect by ultraviolet light.

In general, ultraviolet rays contained in sunlight stimulate the formation of erythema or the production of melanin pigment in skin cells when excessively irradiated to the skin, which may cause blemishes and blemishes, and generate lipid peroxide by reacting with sebum secreted in the epidermis. Not only does it cause skin problems, but it can also cause skin cancer in severe cases. UV light is divided into UV-A (320-400nm), UV-B (280-320nm) and UV-C (200-280nm) depending on its wavelength. Ultraviolet rays are mostly absorbed in the atmosphere, so UV rays that directly affect the human body are known as UV-A and UV-B.

The sunscreen, which is used to prevent skin damage by UV rays, refers to a product that exhibits a sunscreen effect by applying a special substance to certain skin areas. The sunscreen effect is a unit called SPF (Sun Protection Factor). Use it to indicate the degree of blocking of the product. The UV Protection Index is calculated by the FDA (Food and Drug Administration) formula, which is the minimum erythema dose of UV-B without sunscreen and UV-B after sunscreen. The ratio of minimum erythema amount is shown. In other words, it is a multiple of the degree to which the skin of the natural state blocks UV rays, and the higher the UV protection index, the better the blocking of sunlight. This is because the higher the UV protection index, the better the effect, but the worse the fit on the skin and the higher the side effects.

Sunscreens are classified into chemical sunscreens and physical sunscreens. Chemical sunscreens that act as chemical absorption of ultraviolet rays are well known organic blockers such as cinnamic acid, salicylic acid, and benzophenone, and physical sunscreens that act as a mechanism for physical scattering and shielding of ultraviolet rays include titanium dioxide, zinc oxide, and the like. The same inorganic blockers are well known. In the case of chemical sunscreens, the sunscreen effect is excellent, but the wavelength range is narrow, applied to the composition is sticky and bundled, bad feeling and can be absorbed into the skin in the form of molecules, causing skin irritation. . Since most commercial sunscreens contain chemical barriers, high sun protection indexes are not desirable. In the case of the physical sunscreen, it is mainly used to reduce the amount of transmitted ultraviolet rays by reflecting and scattering the ultraviolet rays, and the inorganic compound in the form of ultra fine particles is mainly used.These materials are characterized by a very high refractive index and excellent heat resistance compared to the organic sunscreen. Do. Skin irritation is relatively low compared to chemical sunscreens, but has a disadvantage of causing a heavy feeling of use and whitening phenomenon is not cosmetically appropriate (Patent No. 2003-0046103).

Various studies have been conducted on sunscreens to compensate for the shortcomings of chemical sunscreens and physical sunscreens. First, a form in which chemical sunscreens and physical sunscreens are mixed at an appropriate ratio is a method currently applied to most sunscreen products, but there are fundamental disadvantages described above. In addition, the form of adsorbing titanium dioxide, which is an inorganic barrier agent on the surface of the inorganic material or the polymer particles, or containing an organic barrier agent inside the particle is supplemented in terms of skin safety, but has a disadvantage in that the manufacturing process is complicated and the UV blocking efficiency is not high. Lastly, the inorganic particles such as titanium dioxide and zinc oxide are made of ultra fine particles to compensate for the disadvantages of the existing inorganic blocker, and the form with high efficiency blocking effect can not completely reduce the whitening phenomenon and the feeling of use decreases as the particle size decreases. It has a disadvantage. Organic and inorganic sunscreens made of such chemicals have become a problem because of their side effects, and therefore, they have become interested in natural sunscreens that are harmless to the human body.

As an example of the prior invention regarding natural sunscreens, natural hydroxyanthracene polyglycosides have been reported as sunscreens (Bader et al., Cosmetics & Toiletries, 96 (10), pp67, 1981), and the use of coffee oils as sunscreens. Use has been reported in French Patent No. 2-479-688. Similarly, natural extracts of aloe, francula, senna and cascara containing anthraquinone derivatives have also been reported as useful sunscreens (Fox et al., Cosmetics & Toiletries, 102 (3), pp 41, 1987).

Accordingly, the present inventors have found that when the ginseng extract derived from ginseng and the green tea extract derived from green tea are used at the same time, the synergistic effect has an excellent effect on sun protection compared to the case of using these components, respectively, and completed the present invention. .

Therefore, the present invention is to provide a composition excellent in the sunscreen effect and the skin damage prevention effect by ultraviolet light by using the ginseng extract and green tea extract at the same time.

In order to achieve the above object, the present invention provides a composition for sunscreen containing ginseng extract and green tea extract as an active ingredient.

The composition of the present invention exhibits an effect of blocking ultraviolet rays by preventing ginseng extract and green tea extract, and preventing skin damage caused by ultraviolet rays. Therefore, the composition containing the ginseng extract and the green tea extract is not only excellent in the sunscreen effect, there is no irritation to the skin, it is safe and stable and can be usefully used as an external skin composition or pharmaceutical composition.

The composition of the present invention by providing a ginseng extract and green tea extract as an active ingredient, provides an excellent sunscreen effect.

Hereinafter, the present invention will be described in more detail.

Ginseng (Panax ginseng CA Meyer), which is used as an active ingredient of the present invention, is a plant belonging to the genus Ogapi ginseng, and has been used for about 2,000 years in Korea, China, Japan, etc. Has been used. The ginseng can be used without limitation in the type and lotus root (年根), can be used both ginseng dried or not dried. In addition, the ginseng can be used without limitation to the site, specifically can use the root.

Green tea, which is used as an active ingredient of the present invention, is known to be an excellent antioxidant material among natural functional substances and is one of foods that have recently been of interest. Green tea contains a number of components, including catechin, which is a polyphenolic compound, and is known to be effective in removing free radicals caused by stress in and out of the body due to its excellent pharmacological action and particularly excellent antioxidant properties. The green tea can be used without limitation in the type and cultivation days, it can be used both dried and undried green tea. In addition, the green tea can be used without limitation in the area, specifically, the leaves of green tea can be used.

The extract of the present invention is a substance obtained by extracting a component therein from a natural product, and includes all of them regardless of the method of extraction or the kind of the component. For example, it is a broad concept that includes all components obtained by extracting a component dissolved in a solvent from a natural product using water or an organic solvent, and those obtained by extracting only a specific component such as an oil such as oil.

The ginseng extract and green tea extract of the present invention means a mixture of ginseng extract and green tea extract extract, which can block ultraviolet rays significantly better than the general ginseng extract or green tea extract.

The ginseng extract and the green tea extract of the present invention can be prepared using an extraction method commonly used in the industry, preferably by ultra-high pressure low molecular extraction method which can obtain a large amount of peptide and amino acid components from the material extraction method than the general extraction method can do. The ultra high pressure low molecular extraction method uses a water pressure as a medium as a medium without using gas or heat, and applies various foods and cosmetic raw materials at high pressure (1,000 atm, 100 MPa) to liquefy to ultra low molecules (extracting). Extraction is carried out by using the solvent penetrates into the cell to extract the very low molecular weight agonist. This method is characterized by less nutrient destruction by extraction at room temperature, a large amount of low-molecular amino acids and peptides are extracted, maintains the natural color by low temperature method, and reduces the odor and specific odor due to heat treatment. Specifically, the ginseng and the green tea used in the present invention can be separated and purified from an organic solvent extract or oil obtained by pressing. Extraction solvents include purified water, methanol, ethanol, propanol, isopropanol, butanol, acetone, ether, benzene, chloroform Various solvents such as chloroform, ethyl acetate, methylene chloride, hexane, cyclohexane and petroleum ether may be used alone or in combination.

The composition of the present invention may contain ginseng extract and green tea extract in an amount of 0.001 to 10% by weight relative to the total weight of the composition, preferably, 0.005 to 9.5% by weight of the ginseng extract and green tea extract, respectively , 0.01-9%, 0.03-8.5%, 0.05-8%, 0.07-7.5%, 0.09-7%, 0.1-6.5%, 0.3-6%, 0.5-5.5% or 0.7 It may be contained in an amount of ˜5% by weight.

In the present invention, ginseng extract and green tea extract are used by mixing in the range of 0.1 to 10: 1 by weight. In addition, in order to maximize the synergistic effect of the combination of the two components, preferably used by mixing the ginseng extract and green tea extract in a weight ratio of 0.5 to 9.5: 1, 1 to 9: 1 or 1.5 to 8.5: 1 Can be.

The sunscreen composition according to the present invention can be usefully used for sunscreen protection and skin damage by ultraviolet light.

The composition of the present invention may be formulated as an external composition for skin, in particular a cosmetic composition, and may be formulated containing a cosmetically or dermatologically acceptable medium or base. In addition, the compositions of the present invention may be provided in all formulations suitable for topical application, for example, emulsions obtained by dispersing an oil phase in a solution, an aqueous phase, emulsions obtained by dispersing an aqueous phase in an oil phase, suspensions, solids, gels, powders, It may be provided in the form of a paste, foam or aerosol composition. Compositions of such formulations may be prepared according to conventional methods in the art.

In addition, the composition according to the present invention may include other ingredients in addition to the above-mentioned materials within a range not impairing the main effect, preferably a synergistic effect on the main effect. In addition, the composition according to the present invention may further include a moisturizer, an emulsifier, a UV absorber, a preservative, a fungicide, an antioxidant, a pH adjuster, organic and inorganic pigments, flavoring, cooling agent or limiting agent. The blending amount of the above components can be easily selected by those skilled in the art within the range that does not impair the object and effect of the present invention, the blending amount may be 0.01 to 5% by weight, specifically 0.01 to 3% by weight relative to the total weight of the composition. .

In addition, the compositions of the present invention may be formulated as pharmaceutical compositions. When the composition according to the present invention is applied to a pharmaceutical product, it may be formulated as an oral or parenteral dosage form in the form of a solid, semi-solid or liquid by adding a commercially available inorganic or organic carrier to the active ingredient used in the present invention. , The pharmaceutical composition according to the invention can be administered orally, parenteral, rectal, topical, transdermal, intravenous, intramuscular, intraperitoneal, subcutaneous.

Formulations for oral administration include tablets, pills, granules, capsules, powders, fine granules, powders, emulsions, syrups, pellets and the like. In addition, the formulation for parenteral administration includes injections, drops, ointments, lotions, sprays, suspensions, emulsions, suppositories, and the like. The composition according to the present invention can be easily formulated by carrying out according to a conventional method, and at this time, surfactants, excipients, coloring agents, spices, preservatives, stabilizers, buffers, suspending agents, and other commercially available auxiliaries can be suitably used. have.

The dosage of the active ingredient of the pharmaceutical composition of the present invention will vary depending on the age, sex, weight, pathology and severity of the subject to be administered, the route of administration or the judgment of the prescriber. Determination of a suitable dose based on these factors is within the level of one skilled in the art, the daily dosage of which is for example 0.1 mg / kg / day to 100 mg / kg / day, more specifically 5 mg / kg / day to 50 mg / kg May be, but is not limited to.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention, it will be apparent to those skilled in the art that the scope of the present invention is not to be construed as limited by these examples.

Comparative Example 1 Preparation of Ginseng Extract

1 kg of dried white ginseng was pulverized with a blender, and 5 liters of purified water was added thereto, stirred and extracted with hot water at 38-42 ° C. for 24 hours, and then deposited at 15 ° C. for 1 day. Thereafter, the residue and the filtrate were separated through filter cloth filtration and centrifugation. The separated filtrate was concentrated under reduced pressure to obtain 270 g of the extract.

Comparative Example 2 Preparation of Green Tea Extract

1 kg of the first processed (greening) green tea leaves were pulverized with a blender, and 5 liters of purified water was added thereto, stirred and extracted with hot water at 38-42 ° C. for 24 hours, and then deposited at 15 ° C. for 1 day. Thereafter, the residue and the filtrate were separated through filter cloth filtration and centrifugation. The separated filtrate was concentrated under reduced pressure to obtain 290 g of the extract.

Example 1 Preparation of a Mixture of Ginseng Extract and Green Tea Extract

The ginseng extract prepared in Comparative Example 1 and the green tea extract prepared in Comparative Example 2 were mixed in a weight ratio of 1: 3.

Example 2 Preparation of a Mixture of Ginseng Extract and Green Tea Extract

The ginseng extract prepared in Comparative Example 1 and the green tea extract prepared in Comparative Example 2 were mixed at a weight ratio of 1: 1.

Example 3 Preparation of a Mixture of Ginseng Extract and Green Tea Extract

The ginseng extract prepared in Comparative Example 1 and the green tea extract prepared in Comparative Example 2 were mixed in a weight ratio of 3: 1.

Test Example 1 UV Protection Index Measurement

In order to confirm the UVB blocking effect of the Comparative Examples and Examples, the UV protection index (SPF, Sun Protection Factor) is reported in the general method (J. Soc. Cosmet. Chem., 40, pp 127-133, 1989) Measured according to. Twenty female subjects were irradiated to the back of the test subject by adjusting the amount of ultraviolet light emitted from the solar simulator lamp to the test site to 20-100mj / cm 2. In order to confirm the UV blocking effect of the sample, the sample was uniformly coated with a thickness of 2 μl / cm 2 on the subject's back and left to dry for 15 minutes. The UV irradiation window was attached and fixed to the sample application sites of Comparative Examples 1 and 2 and Examples 1 to 3, and the other portions except the irradiation window were blocked by using a leather and a towel to irradiate ultraviolet rays. After 24 hours of irradiation, the minimum amount of erythema (MED) was determined, and the UV blocking effect was calculated according to Equation 1 below. The UVB blocking effect is expressed by the Sun Protection Factor (SPF), which is the blocking index of UVB. The UVB blocking index refers to the MED on the skin treated with the sunscreen for the amount of UV rays required to generate MED on the untreated skin. It is defined as the amount of ultraviolet light required to generate, and is calculated by the following equation. Therefore, higher SPF means better UVB blocking effect. The results by the above method are shown in Table 1 below.

Test substance UV Protection Index (SPF) Comparative Example 1 16 Comparative Example 2 12 Example 1 25 Example 2 27 Example 3 30

As shown in Table 1, Examples 1 to 3 containing both the ginseng extract and the green tea extract of the present invention were superior to the UV blocking effect than Comparative Examples 1-2.

[Test Example 2] Skin irritation evaluation

In order to determine the skin safety of the composition containing the ginseng extract and green tea extract, using the Comparative Examples 1 and 2 and Examples 1 to 3 according to the composition ratio of the following Table 2 Formulation Examples 1-3 and Comparative Formulation Examples 1-3 were prepared. The unit of content ratio of the following compounding component is weight%.

Ingredient Formulation Example 1 Formulation Example 2 Formulation Example 3 Comparative Formulation Example 1 Comparative Formulation Example 2 Comparative Formulation Example 3 Purified water To 100 To 100 To 100 To 100 To 100 To 100 Example 1 3.0 - - - - - Example 2 - 3.0 - - - - Example 3 - - 3.0 - - - Comparative Example 1 - - - 3.0 - - Comparative Example 2 - - - - 3.0 - Cytostolol 1.7 1.7 1.7 1.7 1.7 1.7 Polyglyceryl 2-oleate 1.5 1.5 1.5 1.5 1.5 1.5 Ceramide 0.7 0.7 0.7 0.7 0.7 0.7 Ceteares-4 1.2 1.2 1.2 1.2 1.2 1.2 cholesterol 1.5 1.5 1.5 1.5 1.5 1.5 Dicetylphosphate 0.4 0.4 0.4 0.4 0.4 0.4 Concentrated glycerin 5.0 5.0 5.0 5.0 5.0 5.0 Sunflower oil 10.0 10.0 10.0 10.0 10.0 10.0 Carboxy Vinyl Polymer 0.2 0.2 0.2 0.2 0.2 0.2 Xanthan Gum 0.3 0.3 0.3 0.3 0.3 0.3 Preservative, incense Quantity Quantity Quantity Quantity Quantity Quantity

In order to determine the occurrence of irritation or allergic reaction through the observation of skin safety, that is, the skin reaction of Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 3 of Table 2, the human body according to the Korea Food and Drug Administration standard skin safety test method A patch test was performed. Twenty women aged 20 to 35 years were selected as test subjects, and Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 3 were applied to both sides, avoiding the midline of the subject, and left for 1 hour. According to the skin irritation was evaluated. The results are shown in Table 3 below.

Formulation Example 1 Formulation Example 2 Formulation Example 3 compare
Formulation Example 1 compare
Formulation Example 2 compare
Formulation Example 3 +++ 0 0 0 0 0 0 ++ 0 0 0 0 0 0 + One 0 0 2 2 2 ± 11 12 12 11 10 9 - 8 8 8 7 8 9

(+++: Strong Trouble, ++: Weak Trouble, +: Weak Trouble, ±: Normal,-: Negative)

As shown in Table 3, Formulation Examples 1 to 3 containing the ginseng extract and green tea extract of the present invention did not cause skin irritation than the group to which Comparative Formulation Examples 1 to 3 were applied. Therefore, it was confirmed that the composition of the present invention can be used as a skin external preparation composition or a pharmaceutical composition without causing skin irritation.

From the above results, it was confirmed that the composition containing the ginseng extract and green tea extract as an active ingredient has an effect of blocking the ultraviolet rays.

[Test Example 3] time stability test

In order to determine the time-lapse stability of the composition containing the ginseng extract and the green tea extract, each of the formulation examples 1 to 3 and Comparative Formulation Examples 1 to 3 of Table 2, each containing 400g in a transparent container at room temperature (25 ℃), high temperature ( 45 ° C.), low temperature (0 ° C.) and Freeze-Thaw Chamber (45 ° C .-- 10 ° C., 24-hour cycle) and the stability over time according to the determination criteria. 4 is shown.

Formulation Example 1 Formulation Example 2 Formulation Example 3 compare
Formulation Example 1 compare
Formulation Example 2 compare
Formulation Example 2 Room temperature (25 ℃) 5 5 5 5 5 5 High temperature (45 ℃) 5 5 5 5 5 5 Low temperature (0 ℃) 5 5 5 5 5 Freezing-thawing room
(45 ℃ ~ -10 ℃) 5 5 5 5 5 5 Cycling test 5 5 5 5 5 5

(5: very stable, 4: stable, 3: slightly unstable, 2: partially separated, 1: completely separated)

As shown in Table 4, Formulation Examples 1 to 3 containing the ginseng extract and the green tea extract of the present invention were stable under all test conditions, so there was no problem in time stability of the formulation.

The composition for sunscreen containing ginseng extract and green tea extract according to the present invention as an active ingredient from the sunscreen effect, safety and time-lapse stability test for the skin is effective in blocking the sun and does not have toxicity and irritation to the skin and is excellent in stability. It was confirmed that the raw material useful as a composition for sunscreen or external skin composition.

Hereinafter, the formulation example of the composition according to the present invention, but the pharmaceutical composition and cosmetic composition is applicable to various formulations, which is intended to explain in detail only, not intended to limit the present invention.

Preparation Example 1 Soft Capsule

150 mg of ginseng extract of Comparative Example 1, 150 mg of green tea extract of Comparative Example 2, palm oil 2 mg, palm hardened oil 8 mg, lead 4 mg and lecithin 6 mg were mixed and 400 mg per capsule was prepared according to a conventional method to prepare a soft capsule.

Preparation Example 2 Tablet

150 mg of ginseng extract of Comparative Example 1, 150 mg of green tea extract of Comparative Example 2, 100 mg of glucose, 50 mg of red ginseng extract, 96 mg of starch and 4 mg of magnesium stearate were added and 40 mg of 30% ethanol was added to form granules and dried at 60 ° C. It was compressed into tablets using a tableting machine.

Preparation Example 3 Granule

150 mg of ginseng extract of Comparative Example 1, 150 mg of green tea extract of Comparative Example 2, 100 mg of glucose, 50 mg of red ginseng extract and 600 mg of starch were mixed and 100 mg of 30% ethanol was added to form granules, followed by drying at 60 ° C to form granules. The next gun was filled. The final weight of the content was 1 g.

[Example 4] Softening Cosmetic (Skin Lotion)

According to the composition described in Table 5 was prepared in the conventional method for the flexible cosmetics.

Compounding ingredient Content (weight%) Ginseng Extract of Comparative Example 1 0.1 Green Tea Extract of Comparative Example 2 0.1 glycerin 3.0 Butylene glycol 2.0 Propylene glycol 2.0 Carboxy Vinyl Polymer 0.1 Fiji-12 nonylphenyl ether 0.2 Polysorbate 80 0.4 ethanol 10.0 Triethanolamine 0.1 Preservative, coloring, flavoring Quantity Purified water Remaining amount

[Example 5] Nutritional Longevity (Milk Lotion)

Nutritional longevity was prepared according to the conventional composition described in Table 6 below.

Compounding ingredient Content (weight%) Ginseng Extract of Comparative Example 1 0.5 Green Tea Extract of Comparative Example 2 0.5 glycerin 3.0 Butylene glycol 3.0 Propylene glycol 3.0 Carboxy Vinyl Polymer 0.1 Beeswax 4.0 Polysorbate 60 1.5 Caprylic / Capric Triglycerides 5.0 Squalane 5.0 Sorbitassquioleate 1.5 Liquid paraffin 0.5 Cetearyl Alcohol 1.0 Triethanolamine 0.2 Preservative, coloring, flavoring Quantity Purified water Remaining amount

Preparation Example 6 Nutrition Cream

Nutritional cream was prepared in a conventional manner according to the composition shown in Table 7.

Compounding ingredient Content (% by weight) Ginseng Extract of Comparative Example 1 1.0 Green Tea Extract of Comparative Example 2 1.0 glycerin 3.0 Butylene glycol 3.0 Liquid paraffin 7.0 Beta Glucan 7.0 Carbomer 0.1 Caprylic / Capric Triglycerides 3.0 Squalane 5.0 Cetearyl Glucoside 1.5 Sorbitan stearate 0.4 Polysorbate 60 1.2 Triethanolamine 0.1 Preservative, coloring, flavoring Quantity Purified water Remaining amount

[Example 7] Massage Cream

To prepare a massage cream in a conventional manner according to the composition shown in Table 8.

Compounding ingredient Content (% by weight) Ginseng Extract of Comparative Example 1 1.5 Green Tea Extract of Comparative Example 2 1.5 glycerin 8.0 Butylene glycol 4.0 Liquid paraffin 45.0 Beta Glucan 7.0 Carbomer 0.1 Caprylic / Capric Triglycerides 3.0 Beeswax 4.0 Cetearyl Glucoside 1.5 Sesqui oleic acid sorbitan 0.9 Vaseline 3.0 paraffin 1.5 Preservative, coloring, flavoring Quantity Purified water Remaining amount

[Example 8] Pack

To prepare a pack in a conventional manner according to the composition described in Table 9.

Compounding ingredient Content (% by weight) Ginseng Extract of Comparative Example 1 0.1 Green Tea Extract of Comparative Example 2 0.1 glycerin 4.0 Polyvinyl alcohol 15.0 Hyaluronic acid extract 5.0 Beta Glucan 7.0 Allantoin 0.1 Nonyl Phenyl Ether 0.4 Polysorbate 60 1.2 Ethanol preservative 6.0 quantity Preservative, coloring, flavoring Quantity Purified water Remaining amount

[Example 9] Ointment

The ointment was prepared in a conventional manner according to the composition described in Table 10 below.

Compounding ingredient Content (% by weight) Ginseng Extract of Comparative Example 1 0.1 Green Tea Extract of Comparative Example 2 0.1 glycerin 8.0 Butylene glycol 4.0 Liquid paraffin 15.0 Beta Glucan 7.0 Carbomer 0.1 Caprylic / Capric Triglycerides 3.0 Squalane 1.0 Cetearyl Glucoside 1.5 Sorbitan stearate 0.4 Cetearyl Alcohol 1.0 Beeswax 4.0 Preservative, coloring, flavoring Quantity Purified water Remaining amount

As described above in detail the specific parts of the present invention, it is apparent to those skilled in the art that such specific description is merely a preferred embodiment, thereby not limiting the scope of the present invention. something to do. Thus, the substantial scope of the present invention will be defined by the appended claims and their equivalents.

Claims (6)

Skin external preparation composition for blocking ultraviolet (UV) -B containing a mixture of ginseng extract and green tea extract as an active ingredient. The composition for external application for skin according to claim 1, wherein the ginseng extract and the green tea extract are each contained in an amount of 0.001 to 10% by weight based on the total weight of the composition. According to claim 1, wherein the ginseng extract and green tea extract is a skin external composition to be mixed in a ratio of 0.1 to 10: 1 by weight. The external preparation composition for skin according to claim 1, which improves skin damage or disease caused by ultraviolet (UV) -B exposure. delete delete