KR102025398B1 - Liposome-coated mineral powder and Cosmetic composition thereof - Google Patents

Abstract

The present invention relates to a mineral powder coated with liposomes and a cosmetic composition containing the same. The present invention, specifically, provides a liposome-coated mineral powder by coating liposomes on the mineral powder, thereby increasing dispersibility, showing excellent formulation stability and improving feeling during use on skin. The liposome-coated mineral powder of the present invention prepared herein can be applied to various cosmetic formulations.

Description

Liposome-coated mineral powder and cosmetic composition containing the same

 The present invention relates to a cosmetic composition using a mineral powder, and more particularly to a cosmetic composition which improves skin applicability and usability by coating liposomes on the mineral powder to modify the mineral surface.

Minerals are used in various industries depending on their physical and chemical properties. Minerals are used as cosmetics in color, colorants, colorants, sebum adsorption, skin regeneration, moisturizing, UV protection, etc., and various formulations such as creams, foundations, mascara, etc. Cosmetic compositions are being developed.

The mica, illite, titanium dioxide, zinc oxide, talc and the like are mainly used in the cosmetic composition for covering the skin spots, blemishes, and the like. These raw materials are mainly used to be processed in the form of a fine powder, poor dispersibility or coalescing, there is a problem that agglomeration occurs to damage the formulation of the cosmetic composition.

On the other hand, minerals used in cosmetics are mostly imported and used, but in Korea, mineral mining is performed in Bonghwa-gun, Gyeongsang-do, Hongseong-gun, Chungnam, Taebaek, Gangwon-do, and Jangseong-gun, Jeonnam. There is a need for development of the composition.

Therefore, the present invention as a cosmetic material using a mineral, to improve the dispersibility of the mineral powder, to develop and provide a new cosmetic material to improve the unique uncomfortable feeling.

Republic of Korea Patent Publication No. 10-2015-0008609 (published on Jan. 23, 2015) relates to a cosmetic composition comprising a natural mineral, including a natural mineral containing quartz, quartz, topaz, tourmaline, loess, pearlite and diatomaceous earth A cosmetic composition is disclosed. Republic of Korea Patent No. 10-1768426 (registered on August 8, 2017) relates to a cream cosmetic for tattoo cover using a cumulus powder surface-coated with camellia oil and a manufacturing method thereof, the coating of camellia powder on cumulus powder One water-in-oil cosmetic composition is disclosed. Republic of Korea Patent Publication No. 10-2012-0005773 (published on Jan. 17, 2012) relates to talc-free powder type color cosmetic composition containing an elite, and functions such as moisturizing, oil and water balance control, hypoallergenic, UV protection. A cosmetic composition exerted is disclosed.

The present invention is to solve the cosmetic formulation stability problem caused by the low dispersibility problem of the mineral powder, and to develop and provide a cosmetic mineral powder with improved skin feel.

In addition, as a cosmetic composition comprising a mineral powder developed in the present invention, to provide a cosmetic composition with improved skin adhesion, moisturizing power.

In addition, various cosmetic formulations including the mineral powder developed in the present invention will be presented.

The present invention provides a liposome-coated mineral powder, characterized in that the surface of the mineralized to a particle size of 10 ~ 100 ㎛ coated with a liposome of 10 ~ 500 nm.

In the present invention, the liposome-coated mineral powder is preferably mixed with 10 to 100 parts by weight of liposomes based on 100 parts by weight of the mineral.

In the present invention, the liposomes, preferably HLB (hydrophilic lipophilic balance) value may be prepared by mixing a surfactant corresponding to the range of 5-15. At this time, the HLB value of the surfactant in the range of 5 to 15 is more preferably hydrogenetirescitin and polyglyceryl-10 dioleate.

In the present invention, the mineral, preferably may be any one or more selected from silicon, aluminum oxide, calcium oxide, iron oxide, potassium oxide, magnesium oxide and titanium dioxide.

In addition, the present invention provides a cosmetic composition comprising the liposome-coated mineral powder of the present invention.

The present invention provides a liposome-coated mineral powder by coating liposomes on the mineral powder, thereby increasing dispersibility and showing excellent formulation stability and improving skin feel.

The present invention also provides a liposome-coated mineral powder having improved skin adhesion and moisturizing power by coating liposomes on the mineral powder.

The liposome-coated mineral powder of the present invention prepared as described above can be applied to various cosmetic formulations.

1 is a flow chart showing a process for preparing a liposome coated mineral powder of the present invention.
2 is a view showing the liposome structure of the present invention.
3 is a view showing an example of the liposome-coated mineral powder of the present invention.
Figure 4 is a photograph taken with a high magnification electron microscope (TEM) of the liposome prepared in the present invention.
5 is a photograph taken with a high magnification electron microscope (SEM) of the liposome-coated mineral powder of the present invention.
6 is a photograph showing an example in which the liposome-coated mineral powder of the present invention is expressed in different colors according to skin tone.
7 is a result of measuring the far-infrared emissivity and radiation energy of the liposome-coated mineral powder of the present invention.
8 is a feeling evaluation results of the cosmetic composition comprising a liposome-coated mineral powder of the present invention.
9 is a graph showing the results of measuring the transdermal moisture loss of the cosmetic composition comprising the liposome-coated mineral powder of the present invention.
10 is a result of measuring the UV protection index of the cosmetic composition comprising a liposome-coated mineral powder of the present invention.
11 is a photograph showing an example of a soap containing a liposome-coated mineral powder of the present invention.

The present invention provides a liposome-coated mineral powder, characterized in that the surface of the mineralized to a particle size of 10 ~ 100 ㎛ coated with a liposome of 10 ~ 500 nm.

The present invention is intended to solve the problem of dispersibility and feeling by modifying the surface of the mineral powder difficult to be used as a raw material in cosmetics due to low dispersibility and skin feeling problems.

In the present invention, the liposome was used to modify the surface of the mineral, but most of the conventional liposomes consist of a liquid phase or a viscous jelly phase, and there is a problem that it is difficult to coat the surface of the powder. In addition, even if the coating on the surface is not uniformly coated, there is a problem that liposomes can be easily separated from the surface of the fine mineral powder. Therefore, the development of a technology that can solve such problems when coating is required, in the present invention by using a liposome of 10 ~ 500 nm size for the mineralized to a particle size of 10 ~ 100 ㎛ size as described above It could be solved.

Through this, in the present invention, the surface of the mineral powder could be uniformly coated with liposomes, and even when added to the cosmetics of various formulations, it was possible to maintain a stable state. In addition, much better skin feel was obtained than using the mineral powder directly (FIG. 3).

The liposome-coated mineral powder of the present invention may be preferably prepared by the method described in FIG. 1, wherein the mineral powder used in the present invention is prepared by crushing and filtering the mineral ore by subjecting it to high temperature baking and drying. It is preferable to use fine mineral powder having a particle size of preferably 10 to 100 μm, preferably plate-shaped. In addition, 'pulverization' performed to obtain a mineral powder having particles of 10 to 100 μm among the technical matters described in FIG. 1 may be performed through a conventional method, and thus a detailed description of the method will be omitted. In addition, since the specific technology for the preparation of liposomes of the matters described in FIG. 1 may be performed with ordinary knowledge, detailed description thereof will be omitted.

On the other hand, in the present invention, the mineral, preferably may be any one or more selected from silicon, aluminum oxide, calcium oxide, iron oxide, potassium oxide, magnesium oxide and titanium dioxide. More preferably, 53 to 63% by weight of silicon, 9 to 19% by weight of aluminum oxide, 3 to 11% by weight of calcium oxide, 1 to 9% by weight of iron oxide, 0.5 to 3.5% by weight of potassium oxide, 1 to 5% by weight of magnesium oxide, and It is good to mix with 3 to 19% by weight of titanium dioxide. When mixed according to the above range may be similar to the skin tone of a person in yellow red or reddish brown, there is an advantage that can be expressed in various skin tones by further adding an inorganic pigment.

Meanwhile, in the present invention, liposomes to be used preferably use a surfactant having a hydrophilic lipophilic balance (HLB) value in the range of 5 to 15, more preferably hydrogenated lecithin, poly Glyceryl-10 dioleate (polyglyceryl-10dioleate) is preferred. Hydrogenity lecithin has an HLB value of 5-7, and polyglyceryl-10 dioleate has an HLB value of 11-14. When using surfactants of these components, liposomes can be stably formed.

On the other hand, the present invention may further include a phytosterol, phytosterol may be used as a raw material to stabilize the liposomes.

On the other hand, when using hydrogenated lecithin, phytosterol, polyglyceryl-10 dioleate in the present invention, preferably hydrogenated lecithin 1 to 10 weight Part, phytosterol 0.5 to 3 parts by weight, polyglyceryl-10 dioleate (polyglyceryl-10 dioleate) is preferably used in a composition of 5 parts by weight. This is because the most stable liposome-coated mineral powder can be prepared at such a compounding ratio.

On the other hand, the liposome-coated mineral powder preparation example of the present invention to briefly explain, the fine mineral powder and the liposomes are mixed, isopropyl alcohol is further mixed with a slurry, slurryed, dried, pulverized, and then filtered to filter liposomes. It will be able to produce a fine mineral powder. Preferably it is good to mix 10 to 100 parts by weight of liposomes based on 100 parts by weight of mineral powder, isopropyl may be used as a solvent. Isopropyl alcohol, used as a solvent, is evaporated during drying so that only liposomes can be coated on the fine mineral powder in the final product. The liposome coating powder thus prepared is shown in FIG. 5. It can be seen that the liposome is uniformly coated on the surface of the plate-like fine mineral powder.

On the other hand, the present invention provides a cosmetic composition comprising a liposome-coated mineral powder of the present invention. In the present invention, the liposome-coated mineral powder can be used to prepare cosmetic compositions in various formulations. Through the following examples and preparations, cream foundation, wash-off type massage cream, sunscreen cream, A cosmetic composition prepared as a cushion BB emulsion, soap formulation is presented.

In addition to the liposome-coated mineral powder of the present invention, the present invention may further prepare a functional cosmetic including various functional ingredients and colorants, and may be expected to be used as a cosmetic composition having excellent coverage by expressing skin tones or complementary colors. In addition, the liposome-coated mineral powder of the present invention is a massage cream formulation, can be utilized as a scrub cream for exfoliation, can be expected skin tone correction, fine wrinkles improvement effect from the exfoliation effect, it is possible to improve the skin clear and smooth.

In addition, the following experimental example confirmed the skin adhesion of the cosmetic composition using the liposome-coated fine mineral powder of the present invention, the skin moisturizing enhancement effect, by adding additional components could be expected to be useful as a functional cosmetic composition.

Hereinafter, the content of the present invention will be described in more detail through the following examples and experimental examples. However, the scope of the present invention is not limited to the following Examples and Experimental Examples, but includes modifications of equivalent technical ideas.

Example 1 Preparation of Mineral Powder

In the present embodiment, a mineral powder was prepared from silicon, aluminum oxide, calcium oxide, iron oxide, potassium oxide, magnesium oxide, and titanium dioxide. Each of the washed mineral gemstones was calcined and dried at 120 ° C., firstly crushed, and firstly filtered through a 50 mesh filter to obtain a mineral powder. Secondary milling of the mineral powder and second filtration with an 800 mesh filter A fine mineral powder granulated into a size of 10-100 μm was obtained. Fine mineral powder was sterilized.

Each fine mineral powder prepared above was blended in a compounding ratio according to Table 1 below to prepare each fine mineral powder mixture.

Mixing ratio of fine mineral powder according to skin tone (wt%) Example 1-1
(Bright skin) Example 1-2
(Medium skin) Example 1-3
(Dark skin) Comparative Example 1
silicon 55 58 60 - Aluminum oxide 13 14 15 - Calcium oxide 7 7 7 - Iron oxide 3 5 7 - Potassium oxide 2 2 2 - Magnesium oxide 3 3 3 - Titanium dioxide 17 11 6 - Mica powder - - - 100

As shown in Table 1, according to the iron oxide content, a mineral powder for light skin, medium skin, and dark skin was prepared. On the other hand, Comparative Example 1 used general industrialized mica powder.

Example 2 Preparation of Mineral Powder Coated with Liposomes

(1) liposome preparation

In this example, liposomes were prepared using isopropyl alcohol as a solvent. Isopropyl alcohol, hydrogenated lecithin, phytosterol, polyglyceryl-10 dioleate, and grape seed oil were mixed and dissolved according to the mixing ratios of Table 2 below. The mixture was stirred for 10 minutes at 3,000 rpm with a homogenizer and then treated three times with a high pressure mixer to prepare liposomes. Liposomes are filled with grape seed oil as a functional material, the particle size was formed to 10 ~ 500 nm. Isopropyl alcohol is a solvent that makes it easy to coat mineral powder.

ingredient Example 2-1
(weight%) Example 2-2
(weight%) Example 2-3
(weight%) Comparative Example 2
(weight%) Hydrogenated Lecithin One 5 5 - Phytosterol 0.5 One 2 5 Polyglyceryl-10 Dioleate One 3 5 - Grape seed oil One 3 7 7 Isopropyl Alcohol 96.5 88 81 88 Sum 100 100 100 100

The liposomes of Example 2-3, which were most stably prepared, were measured with a high magnification electron microscope (TEM). Grape seed oil is encapsulated, and it was confirmed that multiple lamellar liposomes were formed in multiple layers.

(2) Preparation of Mineral Powder Coated with Liposomes

To prepare a fine mineral powder coated with liposomes according to the components and the content according to Table 3 below. Each of the fine mineral powder and the liposomes prepared in Example 2-3 were mixed with 10g, 50g, and 100g, respectively, and 100g of isopropyl alcohol was mixed and slurried. Isopropyl alcohol was used as the solvent and allowed the liposomes to be well coated on the surface of the mineral powder.

ingredient Example 3-1 (g) Example 3-2 (g) Example 3-3 (g) Comparative Example 3 (g) Example 1-1
(Bright skin) 100 - - - Example 1-2
(Medium skin) - 100 - - Example 1-3
(Dark skin) - - 100 - Comparative Example 1
(Mica Powder) - - - 100 Example 2-3
Liposomes 10 50 100 - Isopropyl
Alcohol 100 100 100 100

Each mixture was warmed to dryness and then ground to granulate. Isopropyl alcohol used as the solvent was evaporated during drying and liposomes were coated on the surface of the mineral powder. Each liposome-coated mineral powder was dried at 70 ° C. for 3 hours, followed by 800 mesh filter to finally prepare a liposome-coated fine mineral powder.

Based on the weight according to Table 3, Example 3-1 was 1.9% liposome, Example 3-2 was 9.5% liposome, Example 3-3 was coated 19% liposomes.

The photo of measuring the fine mineral powder coated with the liposome of Example 3-2 by high magnification electron microscope (SEM) is shown in FIG. 5. It was confirmed that the liposome is coated on the surface of the plate-shaped mineral powder. In addition, mineral powders according to the skin tones of Examples 3-1 to 3-3 are shown in FIGS.

Experimental Example 1 Comparison of Far-Infrared Radiation Effect According to Liposomal Coating]

In the present experimental example, the far-infrared emission amount of the fine mineral powder coated with the liposome of Example 3-2 and the fine mineral powder of Example 1-2 was measured to compare the far infrared radiation effect of the fine mineral powder. Each sample was measured by FT-IR at 40 ℃ and the results are shown in Figure 7 below.

As shown in FIG. 7, the far-infrared emissivity of the liposome vesicle-coated mineral (Example 3-2) was 0.97 μm, and the emission energy was measured to be 3.78 × 10 ² W / m ² . The far-infrared emissivity was 0.96 µm and the radiation energy was 3.77 × 10 ² W / m ² .

Accordingly, it was confirmed that far-infrared emissivity or radiation energy was not reduced depending on whether or not liposome coating of the fine mineral powder of the present invention.

Experimental Example 2 Measurement of Anion Emission of Liposome-coated Fine Mineral Powder

In the present experimental example, to determine the negative ion release effect of the fine mineral powder, the amount of negative ions released from the liposome-coated fine mineral powder of Example 3-2 was measured. It was tested at room temperature 22 ℃, humidity 45%, and anion water / 114 / cc condition using charge particle measuring device. The anion released from the measured object was measured and expressed as ION number per unit volume. measured in cc.

[Experimental Example 3: Evaluation of the feeling of use and moisture loss of the cream foundation containing liposome-coated fine mineral powder]

(1) Usability Evaluation

In this Experimental Example, in order to evaluate the feeling of use of the cosmetic composition using the liposome-coated fine mineral powder prepared above, the fine mineral powder of Example 1-2 and the liposome-coated fine mineral powder of Example 3-2 cream Comparison was applied to the foundation formulations.

ingredient Preparation Example 1
(weight%) Comparative Production Example 1
(weight%) A Cyclopentasiloxane
Dimethicone
Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Fiji-10 Dimethicone Copolyol
Cetyl Fiji / Fiji 10/1 Dimethicone 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0 B Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
3.0
2.0
5.0
1.0
3.0 to 100
5.0
5.0
2.0
3.0
3.0
2.0 C Example 3-2 (Liposome Coating)
Example 1-2 (Liposome Uncoated) 20.0
- -
20.0 Sum 100 100

According to Table 4, each of the A phases were weighed and warmed and mixed at 80 ° C., and the C phases were added and homogenized at 3,000 rpm for 10 minutes with a homogenizer, followed by warming and mixing at 80 ° C. by adding B phase. The mixture was dispersed and dispersed to emulsify by stirring for 20 minutes at 3,000 rpm condition with a Niger. Thereafter, the mixture was cooled to 30 ° C. and subjected to a defoaming step to prepare the cosmetic compositions of Preparation Example 1 and Comparative Preparation Example 1, respectively.

Any evaluation group having experience using a cream foundation was allowed to apply the same amount of each of Preparation Example 1 and Comparative Production Example 1 cosmetic composition in the same manner as usual, and to compare the feeling of use. Usability evaluation items were five items of coating force, color expression degree, emulsification stability, softness, and skin fitness, and the evaluation score was 10 points. The average value of the evaluation scores is shown in FIG. 8. The coating power, the color development degree, and the emulsion stability were almost the same level, but in the softness and skin adhesion items, the liposome-coated fine mineral powder of the present invention showed a high average value.

Accordingly, it was confirmed that the liposome-coated fine mineral powder was greatly improved in softness and skin adhesion.

(2) Check the water loss

In the present experimental example was to check the water loss amount of Preparation Example 1 and Comparative Preparation Example 1 cosmetic composition prepared above.

Twenty-one adult women were randomly selected to apply the same amount to each of the Preparation Example 1 and Comparative Preparation Example 1 cosmetic composition, and the amount of water loss was confirmed for 5 weeks at one week intervals. As the skin barrier is strengthened to prevent moisture evaporation, the amount of water loss decreases. Therefore, it should be understood that the lower the value, the better the effect.

The measurement results are shown in FIG. 9 below. As shown in Figure 9, compared with the non-treated group, the amount of water loss in Preparation Example 1 and Comparative Preparation Example 1 was lower, it was confirmed that Preparation Example 1 has a much higher moisturizing effect than Comparative Preparation Example 1.

Experimental Example 4: Confirming the antimicrobial effect of the cosmetic composition comprising a liposome-coated fine mineral powder]

In this Experimental Example, to confirm the antimicrobial effect of the cosmetic composition comprising the liposome-coated micromineral powder of the present invention, the antimicrobial force test was carried out with the cosmetic composition from which the preservative component was removed (increased purified water by the amount excluded). The cosmetic composition used in this experiment was a massage cream formulation, using a wash-off type which is washed with water after application.

ingredient Preparation Example 2
(weight%) A Purified water
glycerin
Butylene Glycol
Carbomer
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
5.0
0.4
0.3
0.2 B Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Polyglyceryl 10 Myristate
Strozedistearate 2.0
2.0
3.0
2.0
1.0
2.0
1.0 C Example 3-2 (Liposome Coating) 15 D Potassium hydroxide
Purified water 0.1
5.0 E Sodium hyaluronate
March extract
Centella asiatica Extract
Spices 0.03
0.5
0.1
0.2 Sum 100

To prepare a cosmetic composition of the massage cream formulation according to Table 5 was carried out antimicrobial experiment. Phase A and phase B were mixed, warmed and melted at 80 ° C., and undispersed at 1,000 to 1500 rpm using a disper. Thereafter, the phase C was gradually introduced into the homogenizer while stirring at 3,000 rpm, followed by stirring for 10 minutes. Phase D was added thereto and stirred at 3,000 rpm for 5 minutes, followed by slow cooling, phase E at 50 ° C., followed by stirring at 3,000 rpm for 3 minutes. Thereafter, while cooling to 30 ℃ through a vacuum and defoaming process to prepare a cosmetic composition of the massage cream formulation.

Inoculated to the same bacteria, E. coli, Staphylococcus aureus and incubated at 37 ℃, and observed for 5 weeks at 1 week intervals are shown in Table 6. (◎: Good, △: Fine contamination, X: Poor)

Test Items sample Result of bactericidal and antimicrobial activity 1 week 2 weeks 3 weeks 4 Weeks 5 Weeks General bacteria No treatment △ △ △ X X Massage cream △ ◎ ◎ ◎ ◎ Escherichia coli No treatment X X X X X Massage cream △ ◎ ◎ ◎ ◎ Staphylococcus aureus No treatment X X X X X Massage cream △ ◎ ◎ ◎ ◎

At week 1, there were about 100 bacteria per 1 cm in width, but after 2 weeks, they were completely killed and showed a clean state. Accordingly, it was confirmed that the cosmetic composition comprising the liposome-coated fine mineral powder of the present invention has excellent antiseptic effect even if it does not contain other preservatives.

Experimental Example 5: Checking the sunscreen effect of the cosmetic composition comprising a liposome-coated fine mineral powder]

In this experimental example, it was intended to confirm the sunscreen effect (in-vitro) of the cosmetic composition comprising the liposome-coated fine mineral powder of the present invention.

ingredient Preparation Example 3
(weight%) A Cyclopentasiloxane
Dimethicone
Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Fiji-10 Dimethicone Copolyol
Cetyl Fiji / Fiji 10/1 Dimethicone
Ethylhexylmethoxycinnamate
Ethylhexylsalicylate 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0
5.0
3.0 B Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
5.0
5.0
3.0
3.0
2.0 C Example 3-2 (Liposome Coating)
Titanium dioxide
Zinc oxide 15.0
5.0
5.0 D Sodium hyaluronate
March extract
Extracted Leaf Extract
Spices 0.1
0.1
0.1
0.2 Sum 100

In accordance with Table 7, the sunscreen cosmetic composition was prepared and tested. Warmly mix phase A to 80 ° C, add phase C homogeneously and disperse homogeneously at 3,000 rpm for 10 minutes, and warm-mix phase B to 80 ° C for 3 minutes at 3,500 rpm with homogenizer. After stirring, it was cooled to 30 ° C. Through the vacuum and defoaming process was prepared a sunscreen cosmetic composition comprising a liposome-coated fine mineral powder.

The blocking effect was confirmed in the UVB index UVB region (SPF), UVA index UVA region of the cosmetic composition prepared above, it was measured by SPF-290 analyzer (SPF-290S, Optometrics Corparation). The measurement results are shown in FIG. 10, and the UV-blocking UVB region was 63.7 and the UVA region was 27.8.

Formulation Example 1: Cream Foundation

The liposome-coated fine mineral powder of the present invention and a liposome-coated fine mineral powder may be mixed to prepare a cream foundation formulation. Various inorganic colors such as titanium dioxide and mica can be added to produce various skin colors.

ingredient Zehung 1-1
(weight%) Formulation Example 1-2
(weight%) Formulation Example 1-3
(weight%) A Cyclopentasiloxane
Dimethicone
Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Fiji-10 Dimethicone Copolyol
Cetyl Fiji / Fiji 10/1 Dimethicone 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0 B Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
3.0
3.0
5.0
1.0
3.0 to 100
5.0
5.0
5.0
3.0
3.0
2.0 to 100
5.0
5.0
5.0
3.0
3.0
2.0 C Example 3-2 (Liposome Coating)
Example 1-2 (Liposome Uncoated)
Titanium dioxide
Mica
Yellow iron oxide
Red iron oxide
Black iron oxide 15.0
15.0
5.0
5.0
1.2
0.3
0.03 20.0
10.0
10.0
10.0
1.3
0.2
0.05 10.0
20.0
15.0
5.0
1.0
0.15
0.07 D Sodium hyaluronate
March extract
Centella asiatica Extract
Spices 0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.2 Sum 100 100 100

According to Table 8, the A phase is warmly mixed at 80 ℃, homogenizer and dispersed for 10 minutes at 3,000rpm condition by adding the C phase, then B phase is added by 80 ℃ warm mixing and homogenizer The mixture was stirred for 20 minutes at 3,500 rpm and mixed to disperse the emulsion. This was cooled to 50 ° C., phase D was added, stirred at 3,500 rpm for 5 minutes with a homogenizer, cooled to 30 ° C., and vacuum degassed to produce the final product.

Formulation Example 2: Wash-off Massage Cream

Wash-off type massage cream formulations can be prepared using liposome coated micromineral powders of the present invention or micromineral powders without liposomes coated. The liposome coated mineral powder may comprise 0.1 to 50% by weight relative to the total weight. Wash off type massage cream is applied to skin with thickness of 2 ~ 3mm and left to stand for 15 minutes and can be washed off with lukewarm water.

ingredient Zehung
2-1
(weight%) Formulation example
2-2
(weight%) Formulation example
2-3
(weight%) Formulation example
2-4
(weight%) Formulation example
2-5
(weight%) A Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Carbomer
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
5.0
2.0
0.1
0.4
0.3
0.2 to 100
5.0
5.0
2.0
0.1
0.4
0.3
0.2 to 100
5.0
5.0
2.0
0.1
0.4
0.3
0.2 to 100
5.0
5.0
2.0
0.1
0.4
0.3
0.2 to 100
5.0
5.0
2.0
0.1
0.4
0.3
0.2 B Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Polyglyceryl 10 Myristate
Strozedistearate 2.0
2.0
3.0
2.0
1.0
2.0
1.0 2.0
2.0
3.0
2.0
1.0
2.0
1.0 2.0
2.0
3.0
2.0
1.0
2.0
1.0 2.0
2.0
3.0
2.0
1.0
2.0
1.0 2.0
2.0
3.0
2.0
1.0
2.0
1.0 C Example 3-2 (Liposome Coating)
Example 1-2 (Liposome Uncoated) -
30 1.0
- 30.0
- 50.0
- 25.0
- D Potassium hydroxide
Purified water 0.1
5.0 0.1
5.0 0.1
5.0 0.1
5.0 0.1
5.0 E Sodium hyaluronate
March extract
Centella asiatica Extract
Spices 0.03
0.5
0.1
0.2 0.03
0.5
0.1
0.2 0.03
0.5
0.1
0.2 0.03
0.5
0.1
0.2 0.03
0.5
0.1
0.2 Sum 100 100 100 100 100

According to the above Table 9, phase A and phase B were mixed, warmed and dissolved at 80 ° C., and undispersed at 1,500 rpm using a disper. This was stirred at 3,000 rpm with a homogenizer, the C phase was slowly added and stirred at 3,000 rpm for 10 minutes, and then D phase was added thereto and stirred at 3,000 rpm for 5 minutes. After cooling, the phase E was added at 45 ° C. and stirred at 3,000 rpm for 3 minutes. Thereafter, the final product was subjected to vacuum and degassing while cooling to 30 ° C.

Formulation Example 3: Cream for UV Protection

The liposome-coated micromineral powder of the present invention and a liposome-coated micromineral powder may be mixed to prepare a sunscreen cream formulation.

ingredient Formulation Example 3-1
(weight%) Formulation Example 3-2
(weight%) Formulation Example 3-3
(weight%) A Cyclopentasiloxane
Dimethicone
Shea Butter
Microcrystalline Wax
Vegetable squalane
Cetylethylhexanoate
Glyceryl Stearate
Fiji-10 Dimethicone Copolyol
Cetyl Fiji / Fiji 10/1 Dimethicone
Ethylhexylmethoxycinnamate
Ethylhexylsalicylate 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0
3.0
2.0 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0
5.0
3.0 8.0
5.0
2.0
1.0
3.0
5.0
2.0
2.0
1.0
7.0
5.0 B Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
3.0
3.0
5.0
1.0
3.0 to 100
5.0
5.0
5.0
3.0
3.0
2.0 to 100
3.0
5.0
7.0
2.0
4.0
1.0 C Example 3-2 (Liposome Coating)
Examples 1-2 (uncoated liposomes)
Titanium dioxide
Zinc oxide -
15.0
5.0
5.0 15.0
-
5.0
5.0 10.0
10.0
5.0
5.0 D Sodium hyaluronate
March extract
Extracted Leaf Extract
Spices 0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.2 Sum 100 100 100

According to Table 10, phase A was warmed and mixed at 80 ° C., and phase C was added and homogeneously dispersed at 3,000 rpm under a homogenizer for 10 minutes. The B phase was heated to 80 ° C., mixed, and stirred for 20 minutes at 3,000 rpm using a homogenizer, followed by mixing and dispersing to facilitate emulsification. Thereafter, the mixture was cooled to 50 ° C, and the D phase was added thereto, stirred with a homogenizer at 3,000 rpm for 5 minutes, cooled to 30 ° C, and vacuum degassed to produce the final product.

Formulation Example 4: Cushion BB Emulsion

Cushion BB emulsion formulations may be prepared by mixing the liposome-coated fine mineral powder of the present invention and the micro-mineral powder not coated with the liposome. Cushion blemish balm formulation is easy to use, has skin tone correction, sunscreen effect, and waterproof, so it is excellent in sustainability.

ingredient Jehungye 4-1
(weight%) Formulation Example 4-2
(weight%) Formulation Example 4-3
(weight%) A Cyclopentasiloxane
Dimethicone
Cetearyl Alcohol
Vegetable squalane
Isononylisononanoate
Cetylethylhexanoate
Glyceryl Stearate
Fiji-10 Dimethicone Copolyol
Cetyl Fiji / Fiji 10/1 Dimethicone
Ethylhexylmethoxycinnamate
Ethylhexylsalicylate 20.0
10.0
2.0
1.0
2.0
2.0
2.0
3.0
1.0
2.0
2.0 20.0
10.0
2.0
1.0
2.0
2.0
2.0
3.0
1.0
2.0
2.0 20.0
10.0
2.0
1.0
2.0
2.0
2.0
3.0
1.0
2.0
2.0 B Example 3-2 (Liposome Coating)
Example 1-2 (Liposome Uncoated)
Titanium dioxide
Zinc oxide -
20.0
3.0
3.0 20.0
-
3.0
3.0 10.0
10.0
3.0
3.0 C Purified water
glycerin
Butylene Glycol
1,2-hexanediol
Ethylhexylglycerin
Xanthan Gum
Hydroxyethyl Cellulose to 100
5.0
3.0
2.0
5.0
1.0
3.0 to 100
5.0
5.0
2.0
3.0
3.0
2.0 to 100
3.0
5.0
2.0
2.0
4.0
1.0 D Sodium hyaluronate
March extract
Centella asiatica Extract
Red Ginseng Extract
Spices 0.1
0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.1
0.2 0.1
0.1
0.1
0.1
0.2 Sum 100 100 100

According to Table 11, the A phase was warmly mixed at 70 ℃, B phase was added and homogeneously dispersed at 3,000 rpm conditions for 10 minutes with a homogenizer. The C phase was warmed to 70 ° C. and mixed, and mixed and dispersed in a homogenizer for 10 minutes at 3,000 rpm for good emulsification. After cooling to 50 ° C., phase D was added, the mixture was stirred at 3,00 rpm for 5 minutes, followed by cooling at 30 ° C. and vacuum degassing to prepare the final product.

Formulation 5: Soap

The liposome-coated micromineral powder of the present invention or the microporous mineral powder without liposomes may be used to prepare soap formulations effective for atopic or acne.

ingredient Formulation Example 5-1
(weight%) Formulation Example 5-2
(weight%) A Lauric acid
Myristic acid
Stearic acid
Grape seed oil
Apricot Seed Oil 5.0
8.0
10.0
8.0
7.0 5.0
8.0
10.0
8.0
7.0 B Purified water
glycerin
Potassium hydroxide
Sodium hydroxide to 100
5.0
-
12.0 to 100
5.0
12.0
- C Example 3-2 (Liposome Coating)
Example 1-2 (Liposome Uncoated)
Spices 10.0
-
0.3 -
10.0
0.3 Sum 100 100

According to Table 12, the A phase was warmed and dissolved at 80 ° C., and the B and C phases were added and stirred at 30 rpm for 2 hours to allow the saponification reaction, and after cooling for 3 days, the resultant was put into a molding mold and solidified. It was. The prepared soap is shown in FIG.

Claims (6)

The surface of the mineralized granules with a size of 10 ~ 100 ㎛ is coated with liposomes of 10 ~ 500 nm,
The mineral is 53 to 63% by weight of silicon, 9 to 19% by weight of aluminum oxide, 3 to 11% by weight of calcium oxide, 1 to 9% by weight of iron oxide, 0.5 to 3.5% by weight of potassium oxide, 1 to 5% by weight of magnesium oxide, and It is mixed with 3 to 19% by weight of titanium dioxide,
The liposome is prepared by mixing 1 to 10 parts by weight of hydrogenated lecithin, 0.5 to 3 parts by weight of phytosterol, and 1 to 5 parts by weight of polyglyceryl-10dioleate. Will be
Liposome-coated mineral powder, characterized in that it has a skin tone correction effect, far infrared radiation effect, moisturizing effect, antibacterial effect and UV protection effect.
The method of claim 1,
The liposome coating is,
Liposome-coated mineral powder, characterized in that 10 to 100 parts by weight of liposomes are mixed based on 100 parts by weight of minerals.
Liposome is coated on the surface of mineral powder by mixing mineral powder and 10 ~ 500 nm liposome, which are granulated into 10 ~ 100 ㎛ size, and have skin tone correction effect, far infrared radiation effect, moisturizing effect, antibacterial effect and UV blocking effect. Preparing liposome coated mineral powder,
The mineral is 53 to 63% by weight of silicon, 9 to 19% by weight of aluminum oxide, 3 to 11% by weight of calcium oxide, 1 to 9% by weight of iron oxide, 0.5 to 3.5% by weight of potassium oxide, 1 to 5% by weight of magnesium oxide, and It is mixed with 3 to 19% by weight of titanium dioxide,
The liposome is prepared by mixing 1 to 10 parts by weight of hydrogenated lecithin, 0.5 to 3 parts by weight of phytosterol, and 1 to 5 parts by weight of polyglyceryl-10dioleate. Method for producing a liposome-coated mineral powder, characterized in that.
delete delete A cosmetic composition comprising the liposome-coated mineral powder of claim 1.

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