KR101684415B1 - Cosmetic composition of water-in-oil with liposome hexacarboxymethyl dipeptide-12 and menufacturing method thereof - Google Patents

Abstract

The present invention relates to a water-in-oil makeup cosmetic composition containing liposomized hexacarboxymethyl dipeptide-12 as an active ingredient, and a method for producing the same. More specifically, the method of the present invention comprises the steps of: (A) dispersing a first mixture mixed with a color base phase (a) and an oil phase (b); (B) producing a second mixture by adding and agitating an aqueous phase (c) after step (A); (C) making viscosity become 20,000-30,000 cPs by adding and mixing a thickener in the second mixture after step (B), and cooling the same; and adding and mixing liposomized hexacarboxymethyl dipeptide-12 after step (C). The makeup cosmetic composition of the present invention contains liposomized hexacarboxymethyl dipeptide-12, so an active ingredient not only stably exists in a makeup cosmetic composition formulation but also shows effects in supplementing skin moisture, improving moisture continuance, and enhancing using sensation.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a makeup cosmetic composition in the form of a water-in-oil containing liposomal hexacarboxymethyl dipeptide-12 as an active ingredient, and a process for producing the same. 2. Description of the Related Art Cosmetic compositions of water-

The present invention relates to a make-up cosmetic composition for in-water type containing liposomal hexacarboxymethyl dipeptide-12 as an active ingredient and a method for producing the same. More specifically, the present invention relates to a makeup cosmetic composition comprising a color base phase (a) (b) dispersing the mixed primary mixture (A); (B) after the step (A), adding the aqueous phase (c) to the primary mixture and stirring to prepare a secondary mixture; (C) cooling the resulting mixture after the step (B), adding the thickener to the secondary mixture, mixing the resulting mixture to a viscosity of 20,000 to 30,000 cPs, and then cooling; And (D) a step (D) of adding liposomal hexacarboxymethyl dipeptide-12 to the mixture after the step (C) and adding the liposomal hexacarboxymethyl dipeptide-12 to the liquid cosmetic composition. .

Cosmetics are classified into various categories according to the use site, purpose of use, or the composition and shape of the product, and they are classified into various kinds of daily cosmetics (skin care cosmetics), makeup cosmetics (skin and color cosmetics), body care ) Cosmetics (body cleansing cosmetics), hair care cosmetics, oral cosmetics, and directional cosmetics.

Make-up cosmetics is a step to express skin color beautifully by applying color to a body such as a face or nail after use of a base product, and to hide skin defects that can not be covered by basic products. This make-up cosmetics make base make-up for uniformly arranging the skin color of the whole face, covering the problems of skin such as spots and freckles, and for making healthy and beautiful skin, and point make-up for emphasizing local colors such as lips, eyes, .

Dual base makeup is one of the most important makeup stages of modern people in recent years, preferring clean, moist skin expression and light feeling. These trends are reflected, and there is a growing demand for formulations with good coverage and good moisture retention and high moisture retention.

When base makeup cosmetics are manufactured for underwater type (O / W) for moisture, the outer skin is water, so the feeling is light and the moisturizing power is excellent immediately after application, but it is easily erased and the covering power is not good. Moisturizing power is lowered.

On the other hand, make-up cosmetics commonly used in the field of cosmetics are made by dispersing a pigment in a traumatic oil phase and using a surfactant having a low hydrophile-lipophile balance (HLB) And stabilizing the emulsified formulation. The higher the pigment content, the better the coverage.

However, the higher the content of the pigment is, the disadvantage is that it feels stiff, the degree of dispersion is decreased, the uniformity of coating is lowered, and the feeling of use is heavy and sticky when applied to the skin.

As described above, when the covering force is increased, the feeling of moisture and feeling of use is remarkably lowered, and when the feeling of feeling and feeling are improved, a problem of poor coverage occurs. Therefore, in order to solve this problem, there is a need for research into a makeup cosmetic composition having a good covering ability and excellent moisture resistance, water retention ability and feeling of use.

Korean Patent Laid-Open Publication No. 10-2016-0017886 (published on Jan. 26, 2016) discloses a composition comprising a peanut extract, which is obtained by liposomalizing a peanut sprout extract and then improving light stability by using PMMA and cyclodextrin . ≪ / RTI > Korean Registered Patent No. 10-1338518 (registered on December 31, 2013) discloses a cosmetic composition comprising 15 to 50 parts by weight of a polyol based on the total weight of the moisturizing cosmetic composition; 5 to 30 parts by weight of an oil containing a silicone-based oil; And 1.0 to 5.0 parts by weight of an emulsifier and has an OD value of 1.0 or less in the visible light region.

Disclosure of Invention Technical Problem [8] The present invention is intended to solve the problems of the prior art described above, and it is an object of the present invention to provide a makeup cosmetic composition having a good covering power and excellent moisture resistance, moisture retentivity and feel.

To achieve the above object, the present invention provides a cosmetic cosmetic composition comprising liposomal hexacarboxymethyl dipeptide-12 as an active ingredient. Since the makeup cosmetic composition of the present invention contains the above-mentioned liposomized hexacarboxymethyldipeptide-12, not only the active ingredient is stably present in the makeup cosmetic composition formulation, but also the skin moisture replenishment and moisture persistence is increased, Can be improved.

In the makeup cosmetic composition of the present invention, the liposomized hexacarboxymethyldipeptide-12 is preferably selected from the group consisting of purified water, glycerin, caprylic / capric acid triglyceride ), Polysorbate, steareth-2, steareth-21, cetyl alcohol, stearic acid, isohexadecane and isohexadecane. Glyceryl acrylate / acrylic acid to be liposomized,

More preferably, 0.1 to 7.5% by weight of hexakarboxymethyldipeptide-12 is dissolved in 4 to 10% by weight of purified water, 10 to 16% by weight of glycerin, 20 to 20% by weight of caprylic / capric acid triglyceride, 0.1 to 2.5% by weight of stearoth-2, 0.1 to 2.5% by weight of steareth-21, cetyl alcohol (cetyl alcohol) of 20 to 60% by weight, polysorbate 12 to 18% 0.1 to 2.5% by weight of stearic acid, 1.5 to 7.0% by weight of stearic acid, 1.5 to 7.0% by weight of isohexadecane and 0.1 to 7.5% by weight of glyceryl acrylate / acrylic acid, To be liposomized. Thus, liposomal hexacarboxymethyldipeptide-12 exerts excellent effects on skin moisture replenishment and water retention enhancement.

On the other hand, in the make-up cosmetic composition of the present invention, the liposomization can be performed by any conventional method known in the art.

Meanwhile, the makeup cosmetic composition of the present invention may be, for example, a single formulation selected from a solution, a suspension, an emulsion, a paste, a gel, a cream, a lotion, a powder and a foundation.

The present invention also relates to a method for producing a color image, comprising the steps of: (A) dispersing a primary mixture obtained by mixing a color base phase (a) and an oil phase (b); (B) after the step (A), adding the aqueous phase (c) to the primary mixture and stirring to prepare a secondary mixture; (C) cooling the resulting mixture after the step (B), adding the thickener to the secondary mixture, mixing the resulting mixture to a viscosity of 20,000 to 30,000 cPs, and then cooling; And (D) a step (D) of adding liposomal hexacarboxymethyl dipeptide-12 to the mixture after the step (C). ≪ / RTI >

Meanwhile, in the method for producing a makeup cosmetic composition according to the present invention, the dispersion of step (A) includes pulverization and stirring, and all the dispersion methods commonly used in the art may be used. For example, mill. < / RTI >

The color base phase (a) of the step (A) is preferably selected from the group consisting of ethylhexyl methoxycinnamate, titanium dioxide, zinc oxide (zinc oxide) oxide, silica, disteardimonium hectorite, iron oxides, and triethoxycaprylylsilane. It is also preferred that the composition comprises at least one of the following:

On the other hand, the oil phase (b) of the step (A) is preferably selected from the group consisting of isoamyl p-methoxycinnamate, cyclopentasiloxane, cetylpyridine / cetyl / PEG / PPG-10/1 dimethicone), cyclohexasiloxane, diphenylsiloxy phenyl trimethicone, hexyl laurate, polyglyceryl-4 isostearate polyglyceryl-4 isostearate, sorbitan isostearate, and beeswax.

On the other hand, the water phase (c) in the step (B) is preferably water, glycerin, dipropylene glycol, niacinamide, magnesium sulfate, methylpropanediol methyl propanediol, phenoxyethanol, chlorphenesin, and adenosine.

On the other hand, the cooling in the step (C) may be to lower the temperature of the secondary mixture to which the thickener is added to 40 to 60 ° C.

On the other hand, the liposomized hexacarboxymethyl dipeptide-12 of step (D) is preferably prepared by mixing hexacarboxymethyl dipeptide-12 with purified water, glycerin, caprylic / capric acid triglyceride / capric acid triglyceride, polysorbate, steareth-2, steareth-21, cetyl alcohol, stearic acid, isohexadecane, (isohexadecane) and glyceryl acrylate / acrylic acid to be liposomized,

More preferably, the liposomized hexacarboxymethyl dipeptide-12 comprises 0.1 to 7.5% by weight of hexacarboxymethyldipeptide-12, preferably 4 to 10% by weight of purified water, 10 to 16% by weight of glycerin, 20 to 60% by weight of caprylic / capric acid triglyceride, 12 to 18% by weight of polysorbate, 0.1 to 2.5% by weight of steareth-2, 0.1 to 2.5% by weight of stearoth-21, 0.1 to 2.5% by weight of cetyl alcohol, 1.5 to 7.0% by weight of stearic acid, 1.5 to 7.0% by weight of isohexadecane, And 0.1 to 7.5% by weight of glyceryl acrylate / acrylic acid, and liposomized.

On the other hand, the makeup cosmetic composition of the present invention may be used alone or in combination, or may be used in combination with other cosmetic compositions other than the present invention. In addition, the cosmetic composition according to the present invention can be used according to a conventional method of use, and may be used in a different number of times depending on the skin condition or taste of the user.

Since the makeup cosmetic composition of the present invention contains liposomized hexacarboxymethyldipeptide-12, not only the active ingredient is stably present in the makeup cosmetic composition formulation, but also exhibits the effect of replenishing skin moisture, increasing moisture persistence and improving feeling do.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a production process diagram of a water-in-oil type (W / O) BB cream containing the liposomal hexasarboxymethyldipeptide-12 of the present invention as an active ingredient.
FIG. 2 is a production process diagram of an underwater type (O / W) BB cream containing liposomized hexacarboxymethyldipeptide-12 as an active ingredient.

Hereinafter, the structure of the present invention will be described in detail with reference to the following examples. However, the scope of the present invention is not limited to the following embodiments, and includes modifications of equivalent technical ideas.

[ Example  One: Liposomal Hexacarboxy methyl Dipeptide - 12  (W / O) BB cream containing active ingredient as a water-in-oil type (W / O)

In this Example, a makeup cosmetic composition (BB cream) in water-in-oil type (W / O) containing liposomized hexacarboxymethyldipeptide-12 as an active ingredient was prepared.

< Hexacarboxy methyl Dipeptide -12 Liposomalization >

7 g of purified water, 13 g of glycerin, 40 g of caprylic / capric acid triglyceride, 15 g of polysorbate, 1.3 g of steareth-2, 1.3 g of cetyl alcohol, 1.3 g of cetyl alcohol, 3 g of stearic acid, 3 g of isohexadecane and 10 g of glyceryl acrylate / acrylic acid, , And 2.6 g of hexacarboxymethyldipeptide-12 (trade name: Aquatide-2, manufactured by INCOSPHAM CO., LTD.) Were mixed to liposomalize hexacarboxymethyldipeptide-12.

< BB Creamy  Manufacturing>

The mixture obtained by mixing the color base phase and the oil phase shown in Table 1 was pulverized and agitated three times with a three-roll mill and dispersed evenly.

The mixture was dispersed with a 3-roll mill, and the aqueous phase of the following Table 1 was slowly added thereto, followed by stirring with a homogenizer.

Thereafter, the thickening agent shown in the following Table 1 was further added and homogeneously mixed so as to have a viscosity of 20,000 to 30,000 cPs. Thereafter, the mixture was cooled to 50 ° C, and the liposomized hexacarboxymethyldipeptide-12 prepared above was slowly added , And BB cream was prepared by homogeneous mixing (see Fig. 1).

PHASE INCI NAME CONTENTS
(weight%) Paid Isoamyl p-methoxy cinnamate
(isoamyl p-methoxycinnamate) 5.00 Cyclopentasiloxane
(cyclopentasiloxane) 10.00 Cetyl phage / piperazine-10/1 dimethicone
(cetyl / PEG / PPG-10/1 dimethicone) 3.00 Cyclohexasiloxane &lt; RTI ID = 0.0 &gt; 7.00 Diphenylsiloxy phenyl trimecicone
(diphenylsiloxy phenyl trimethicone) 5.00 Hexyl laurate 2.00 Polyglyceryl-4 isostearate
(polyglyceryl-4 isostearate) 1.00 Sorbitan isostearate &lt; RTI ID = 0.0 &gt; 1.00 Beeswax 1.00 Color base image Ethylhexyl methoxycinnamate
(ethylhexyl methoxycinnamate), 7.00 Titanium dioxides, 6.00 Zinc oxide, 4.00 Silica 0.50 Disteardimonium hectorite, 0.50 Iron oxides CI 77491 0.60 Triethoxycaprylylsilane &lt; / RTI &gt; 0.05 Iron oxides CI 77492 0.25 Iron oxides CI 77499 0.10 Awards Water heated to &lt; RTI ID = 0.0 &gt; 80 C & to 100 Glycerin, 3.00 Dipropylene glycol 2.00 Niacinamide 2.00 Magnesium sulfate 1.00 Methyl propanediol &lt; RTI ID = 0.0 &gt; 2.00 Phenoxyethanol 0.30 Chlorphenesin 0.15 Adenosine 0.04 Incrementer Hydroxyethylcellulose &lt; RTI ID = 0.0 &gt; 0.10 additive
(Active ingredient) Hexacarboxymethyldipeptide-12 2.00 Sum 100

[ Comparative Example  One: Not liposomized  Not Hexacarboxy methyl Dipeptide - 12  Active ingredient Water type (W / O) BB cream production]

In this Comparative Example 1, hexacarboxymethyldipeptide-12 was not liposomized but was put in a raw material state to prepare a BB cream.

(Product name: Aquatide-2, manufactured by INCOSPHAM CO., LTD.) As an active ingredient, instead of liposomal hexacarboxymethyldipeptide-12, was used instead of liposomal hexacarboxymethyldipeptide- A BB cream was prepared in the same manner as in Example 1 above.

[Comparative Example 2: preparation of an underwater type (O / W) BB cream containing liposomal hexacarboxymethyldipeptide-12 as an active ingredient]

In this comparative example, an attempt was made to prepare an underwater type (O / W) makeup cosmetic composition (BB cream) containing liposomal hexacarboxymethyldipeptide-12 as an active ingredient.

< Hexacarboxy methyl Dipeptide -12 Liposomalization >

7 g of purified water, 13 g of glycerin, 40 g of caprylic / capric acid triglyceride, 15 g of polysorbate, 1.3 g of steareth-2, 1.3 g of cetyl alcohol, 1.3 g of cetyl alcohol, 3 g of stearic acid, 3 g of isohexadecane and 10 g of glyceryl acrylate / acrylic acid, , And 2.6 g of hexacarboxymethyldipeptide-12 (trade name: Aquatide-2, manufactured by INCOSPHAM CO., LTD.) Were mixed to liposomalize hexacarboxymethyldipeptide-12.

< BB Creamy  Manufacturing>

The mixture obtained by mixing the color base phase and the oil phase shown in Table 2 below was pulverized and agitated three times by a three-roll mill and dispersed evenly.

A mixture obtained by dispersing the water phase of the following Table 2 in a 3-roll mill was slowly added thereto, followed by stirring with a homogenizer.

Thereafter, the thickening agent shown in the following Table 2 was further added and homogenized to have a viscosity of 20,000 to 30,000 cPs. Thereafter, the mixture was cooled to 50 ° C, and the liposomized hexacarboxymethyldipeptide-12 prepared above was slowly added , And BB cream was prepared by homogeneous mixing (see Fig. 2).

PHASE INCI NAME CONTENTS
(weight%) Awards Water heated to &lt; RTI ID = 0.0 &gt; 80 C & to 100 Methyl propanediol &lt; RTI ID = 0.0 &gt; 3.00 1,2-Hexanediol &lt; / RTI &gt; 2.00 Glycerin 2.00 Niacinamide 2.00 Adenosine 0.04 Color base Titanium dioxde (CI 77891) 6.00 Iron oxides CI 77492 0.60 Iron oxides CI 77491, 0.25 Black oxide of iron CI 77499 0.10 Paid Ethylhexyl methoxycinnamate
(ethylhexyl methoxycinnamate) 7.50 Caprylic / capric acid triglyceride
(caprylic / capric acid triglyceride) 5.00 Glyceryl stearate &lt; RTI ID = 0.0 &gt; 1.00 Cetyl phage / piperazine-10/1 dimethicone
(cetyl / PEG / PPG-10/1 dimethicone) 3.00 PEG-100 stearate (PEG-100 stearate) 0.50 Polysorbate 80 (polysorbate 80) 0.50 Cetearyl alcohol &lt; RTI ID = 0.0 &gt; 1.00 Sorbitan sesquioleate &lt; RTI ID = 0.0 &gt; 0.50 Ammonium acryloyldimethyltaurate / Vpicopolymer
(ammonium acryloyldimethyltaurate / VP Copolymer) 1.00 Incrementer Polyacrylate-13 (Polyacrylate-13) 0.30 Polyisobutene 0.10 Polysorbate 20 (Polysorbate 20) 0.10 additive Hexacarboxymethyldipeptide-12 2.00 Sum 100

[ Experimental Example  1: Sensory evaluation of BB cream]

The BB cream of Example 1 and the BB cream of Comparative Examples 1 and 2 prepared according to the method of manufacturing makeup cosmetic composition of the present invention were subjected to preliminary training on the sensual characteristics of cosmetics for 30 general people, The cream was evaluated for the six items of moistness, color (covering power), fragrance, spreadability, stickiness, overall acceptability.

The 5-point symbol scale was used for the sensory evaluation, and the higher the score, the better the score. The results of the sensory evaluation were summarized in Table 3 below.

Moistness color
(Coverage) Scent Brittle Stickiness Overall likelihood 8 am 8 pm 8 am 8 pm 8 am 8 am 8 am Example 1 4.06 3.75 3.73 3.54 3.10 3.96 3.96 3.80 Comparative Example 1 3.13 2.50 3.40 3.02 2.63 3.26 3.60 3.33 Comparative Example 2 3.43 2.70 3.73 2.73 3.16 3.13 3.46 3.53

As a result of the evaluation, Example 1 of the present invention is characterized in that 'a make-up cosmetic composition for in-water type (Comparative Example 1) containing' hexasarboxymethyldipeptide-12 without liposomes 'as an active ingredient (Comparative Example 1)' and a liposomalized hexacarboxymethyldipeptide- Compared to Comparative Examples 2 and 3 ', the moisturizing and spreading properties were good and the stickiness was reduced as compared to Comparative Examples 1 and 2, as compared with the underwater type makeup cosmetic composition containing hexacarboxymethyl dipeptide-12 as an active ingredient (Comparative Example 2) appear.

In Example 1 of the present invention, the decrease in the number of points of moistness and color (covering power) with time was lower than those of Comparative Examples 1 and 2, and it was confirmed that the color (covering power) I could.

Claims (10)

It contains liposomal hexacarboxymethyl dipeptide-12 as an active ingredient,
The liposomal hexacarboxymethyldipeptide-12 was prepared by mixing hexacarboxymethyldipeptide-12 with purified water, glycerin, caprylic / capric acid triglyceride, polysorbate, Stearate-2, steareth-21, cetyl alcohol, stearic acid, isohexadecane, and glyceryl acrylate / acrylic acid. (W / O) make-up cosmetic composition according to claim 1,
delete The method according to claim 1,
The liposomalized hexacarboxymethyldipeptide-12 is a liposomal,
0.1 to 7.5% by weight of hexacarboxymethyldipeptide-12 is mixed with 4 to 10% by weight of purified water, 10 to 16% by weight of glycerin, 20 to 60% by weight of caprylic / capric acid triglyceride, 0.1 to 2.5% by weight of a polysorbate, 0.1 to 2.5% by weight of steareth-2, 0.1 to 2.5% by weight of steareth-21, 0.1 to 2.5% by weight of cetyl alcohol, By weight of stearic acid, 1.5 to 7.0% by weight of stearic acid, 1.5 to 7.0% by weight of isohexadecane and 0.1 to 7.5% by weight of glyceryl acrylate / acrylic acid, (W / O) makeup cosmetic composition.
The method according to claim 1,
In the cosmetic composition,
(W / O) makeup cosmetic composition as claimed in claim 1, wherein the composition is a solution, suspension, emulsion, paste, gel, cream, lotion, powder and foundation.
(A) dispersing a primary mixture obtained by mixing the color base phase (a) and the oil phase (b);
(B) after the step (A), adding the aqueous phase (c) to the primary mixture and stirring to prepare a secondary mixture;
(C) cooling the resulting mixture after the step (B), adding the thickener to the secondary mixture, mixing the resulting mixture to a viscosity of 20,000 to 30,000 cPs, and then cooling; And
(D) mixing the liposomalized hexacarboxymethyl dipeptide-12 with the liposomized dipeptide-12 after the step (C)
The liposomal hexacarboxymethyl dipeptide-12 of step (D) was prepared by dissolving hexacarboxymethyl dipeptide-12 in purified water, glycerin, caprylic / capric acid triglyceride ), Polysorbate, steareth-2, steareth-21, cetyl alcohol, stearic acid, isohexadecane and isohexadecane. (W / O) makeup cosmetic composition characterized in that it is mixed with glyceryl acrylate / acrylic acid to be liposomized.
6. The method of claim 5,
The color base image (a) of the step (A)
Ethylhexyl methoxycinnamate, titanium dioxde, zinc oxide, silica, disteardimonium hectorite, iron oxides, and triethoxysilane. (W / O) makeup cosmetic composition according to any one of claims 1 to 3, wherein the composition is composed of triethoxycaryl silane.
6. The method of claim 5,
The oil phase (b) of the step (A)
Isoamyl p-methoxycinnamate, cyclopentasiloxane, cetyl / PEG / PPG-10/1 dimethicone, cyclohexasiloxane, cyclohexasiloxane, diphenylsiloxy phenyl trimethicone, hexyl laurate, polyglyceryl-4 isostearate, sorbitan isostearate, sorbitan isostearate, (W / O) makeup cosmetic composition as claimed in any one of claims 1 to 7, characterized in that the composition is composed of beeswax.
6. The method of claim 5,
The water phase (c) in the step (B)
But are not limited to, water, glycerin, dipropylene glycol, niacinamide, magnesium sulfate, methyl propanediol, phenoxyethanol, chlorophenesin, and adenosine. The method of claim 1, wherein the composition is a water-in-oil (W / O) cosmetic composition.
delete 6. The method of claim 5,
The liposomized hexacarboxymethyl dipeptide-12 of step (D)
0.1 to 7.5% by weight of hexacarboxymethyldipeptide-12 is mixed with 4 to 10% by weight of purified water, 10 to 16% by weight of glycerin, 20 to 60% by weight of caprylic / capric acid triglyceride, 0.1 to 2.5% by weight of a polysorbate, 0.1 to 2.5% by weight of steareth-2, 0.1 to 2.5% by weight of steareth-21, 0.1 to 2.5% by weight of cetyl alcohol, Is mixed with 1.5 to 7.0% by weight of stearic acid, 1.5 to 7.0% by weight of isohexadecane and 0.1 to 7.5% by weight of glyceryl acrylate / acrylic acid to form liposomes (W / O) makeup cosmetic composition.

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