CN114053202B - Sun-screening composition and sun-screening agent - Google Patents
Sun-screening composition and sun-screening agent Download PDFInfo
- Publication number
- CN114053202B CN114053202B CN202111651582.6A CN202111651582A CN114053202B CN 114053202 B CN114053202 B CN 114053202B CN 202111651582 A CN202111651582 A CN 202111651582A CN 114053202 B CN114053202 B CN 114053202B
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- China
- Prior art keywords
- pearl powder
- surface modified
- sun
- modified pearl
- sunscreen composition
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- 239000000516 sunscreening agent Substances 0.000 title claims abstract description 112
- 239000000203 mixture Substances 0.000 title claims abstract description 79
- 238000012216 screening Methods 0.000 title abstract description 31
- 239000000843 powder Substances 0.000 claims abstract description 123
- 230000000475 sunscreen effect Effects 0.000 claims abstract description 60
- 239000002245 particle Substances 0.000 claims abstract description 27
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 7
- MSRJTTSHWYDFIU-UHFFFAOYSA-N octyltriethoxysilane Chemical compound CCCCCCCC[Si](OCC)(OCC)OCC MSRJTTSHWYDFIU-UHFFFAOYSA-N 0.000 claims description 33
- 229960003493 octyltriethoxysilane Drugs 0.000 claims description 33
- GYDYJUYZBRGMCC-INIZCTEOSA-N (2s)-2-amino-6-(dodecanoylamino)hexanoic acid Chemical group CCCCCCCCCCCC(=O)NCCCC[C@H](N)C(O)=O GYDYJUYZBRGMCC-INIZCTEOSA-N 0.000 claims description 29
- 238000002156 mixing Methods 0.000 claims description 24
- -1 lauryl PEG-9 Chemical compound 0.000 claims description 22
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 20
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 18
- 239000006185 dispersion Substances 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 18
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 18
- 239000011259 mixed solution Substances 0.000 claims description 17
- 239000000243 solution Substances 0.000 claims description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000004408 titanium dioxide Substances 0.000 claims description 10
- 239000011787 zinc oxide Substances 0.000 claims description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- 230000008569 process Effects 0.000 claims description 9
- 239000000839 emulsion Substances 0.000 claims description 8
- 239000002738 chelating agent Substances 0.000 claims description 7
- 239000003974 emollient agent Substances 0.000 claims description 7
- 239000003995 emulsifying agent Substances 0.000 claims description 7
- 239000003906 humectant Substances 0.000 claims description 7
- 239000003755 preservative agent Substances 0.000 claims description 7
- 230000002335 preservative effect Effects 0.000 claims description 7
- 239000003381 stabilizer Substances 0.000 claims description 7
- 239000002562 thickening agent Substances 0.000 claims description 7
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 229920006037 cross link polymer Polymers 0.000 claims description 6
- DTPCFIHYWYONMD-UHFFFAOYSA-N decaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO DTPCFIHYWYONMD-UHFFFAOYSA-N 0.000 claims description 6
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 6
- 239000003607 modifier Substances 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 4
- 238000005507 spraying Methods 0.000 claims description 4
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 3
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 3
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 claims description 3
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 claims description 3
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- 239000004375 Dextrin Substances 0.000 claims description 3
- 229920001353 Dextrin Polymers 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 3
- 240000007817 Olea europaea Species 0.000 claims description 3
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 3
- 229940036350 bisabolol Drugs 0.000 claims description 3
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 3
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 3
- 229920001577 copolymer Polymers 0.000 claims description 3
- 235000019425 dextrin Nutrition 0.000 claims description 3
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 3
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 claims description 3
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 3
- 229940102552 disteardimonium hectorite Drugs 0.000 claims description 3
- 150000002148 esters Chemical class 0.000 claims description 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 3
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 claims description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 3
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 3
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 3
- 229960002216 methylparaben Drugs 0.000 claims description 3
- VAMFXQBUQXONLZ-UHFFFAOYSA-N n-alpha-eicosene Natural products CCCCCCCCCCCCCCCCCCC=C VAMFXQBUQXONLZ-UHFFFAOYSA-N 0.000 claims description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 3
- 229940049964 oleate Drugs 0.000 claims description 3
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 3
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 claims description 3
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 229960005078 sorbitan sesquioleate Drugs 0.000 claims description 3
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 3
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims 1
- 229940035437 1,3-propanediol Drugs 0.000 claims 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 claims 1
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims 1
- 239000011049 pearl Substances 0.000 abstract description 107
- 230000000694 effects Effects 0.000 abstract description 16
- 239000002537 cosmetic Substances 0.000 abstract description 5
- 210000003491 skin Anatomy 0.000 description 21
- 239000000047 product Substances 0.000 description 15
- 239000002994 raw material Substances 0.000 description 13
- 238000012360 testing method Methods 0.000 description 13
- 230000037072 sun protection Effects 0.000 description 11
- 230000000052 comparative effect Effects 0.000 description 10
- 238000010438 heat treatment Methods 0.000 description 10
- 230000005856 abnormality Effects 0.000 description 8
- 239000011248 coating agent Substances 0.000 description 7
- 238000000576 coating method Methods 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 238000001816 cooling Methods 0.000 description 6
- 238000007599 discharging Methods 0.000 description 6
- 238000009472 formulation Methods 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 5
- 230000002087 whitening effect Effects 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000005855 radiation Effects 0.000 description 4
- 208000003351 Melanosis Diseases 0.000 description 3
- 230000003796 beauty Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- WSMYVTOQOOLQHP-UHFFFAOYSA-N Malondialdehyde Chemical compound O=CCC=O WSMYVTOQOOLQHP-UHFFFAOYSA-N 0.000 description 2
- 102000019197 Superoxide Dismutase Human genes 0.000 description 2
- 108010012715 Superoxide dismutase Proteins 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000005282 brightening Methods 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- XJFGDLJQUJQUEI-UHFFFAOYSA-N dodecyl decanoate dodecyl octanoate Chemical compound CCCCCCCCCCCCOC(=O)CCCCCCC.CCCCCCCCCCCCOC(=O)CCCCCCCCC XJFGDLJQUJQUEI-UHFFFAOYSA-N 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 229940118019 malondialdehyde Drugs 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000011056 performance test Methods 0.000 description 2
- 229940048845 polyglyceryl-3 diisostearate Drugs 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010014970 Ephelides Diseases 0.000 description 1
- 206010016936 Folliculitis Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003471 anti-radiation Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000003889 chemical engineering Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
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- 239000007857 degradation product Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 238000009775 high-speed stirring Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000001782 photodegradation Methods 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/61—Surface treated
- A61K2800/612—By organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
The application provides a sun-screening composition and a sun-screening agent, and belongs to the technical field of cosmetics. A sunscreen composition comprising: 0.5-5 wt% of surface modified pearl powder and 15-45 wt% of physical sun-screening agent. The contact angle of the surface modified pearl powder is 100-140 degrees. The particle size of the surface modified pearl powder is 1-10 mu m. The surface modified pearl powder with proper particle size is selected to be compounded with the physical sun-screening agent, so that the sun-screening index of the sun-screening product added with the physical sun-screening agent is effectively improved. The surface modified pearl powder has good compatibility in a sun-proof product system added with a physical sun-proof agent, and can keep the activity efficacy of pearls.
Description
Technical Field
The application relates to the technical field of cosmetics, in particular to a sun-screening composition and a sun-screening agent.
Background
In hot summer outdoors, ultraviolet rays in sunlight can influence the cuticle and dermis layers of the skin, so that the skin is sunburned, peeled, sunburned and the like, and the skin is damaged. And the barrier function of the skin after sun-drying is weakened, the water loss is serious, and ultraviolet rays can induce skin cells to release various inflammatory mediators to excite inflammatory reaction. Meanwhile, the ultraviolet rays generate excessive free radicals inside and outside the epidermal cells, so that abnormal cell activities are caused, and skin aging is promoted. The damage to human health caused by excessive ultraviolet radiation is increasingly aggravated, and protection against ultraviolet radiation is an extremely urgent problem. Therefore, sun protection is very important, and sun protection products are becoming daily skin care products. The development of safe and effective sun protection products is a potential branch of modern fine chemical engineering. Skin-nourishing type sun cream with both sun-proof and skin-care functions is gradually favored in recent years. With the development of the global environment-friendly industry, more areas in the sea are forbidden to use sun-screening products in the future, the sun-screening product market is affected, and the components of the sun-screening products in the future are more environment-friendly. It is expected that sun protection products will gradually evolve towards safe and environment-friendly.
The physical sun protection has a relatively wide sun protection spectrum, can refract and reflect various ultraviolet rays, and has relatively strong sun protection capability. And is inert in itself, does not photodegradation, and does not have the problem of absorption by the skin. The physical sun-screening agent can be coated for sun screening without waiting and frequent coating. Safe and efficient, and is very popular with consumers.
At present, most common sun cream is prepared by crushing pearls and then directly adding the crushed pearls into the sun cream, and the prepared pearl powder particles have large specific surface area, are easy to agglomerate, are not easy to absorb, even easily block pores to cause folliculitis, and influence the exertion of the efficacy of the pearl powder. Not only the sun-screening efficacy of the sun-screening composition cannot be improved, but also the skin feel of the sun-screening composition is affected to a certain extent.
Disclosure of Invention
The application provides a sun-screening composition and a sun-screening agent, which can improve the compatibility of pearl powder in the sun-screening agent and improve the coordination with a physical sun-screening system.
Embodiments of the present application are implemented as follows:
in a first aspect, the present examples provide a sunscreen composition comprising: 0.5-5 wt% of surface modified pearl powder and 15-45 wt% of physical sun-screening agent.
The contact angle of the surface modified pearl powder is 100-140 degrees.
The particle size of the surface modified pearl powder is 1-10 mu m.
In the technical scheme, the surface modified pearl powder with proper particle size is selected to be compounded with the physical sun-screening agent, so that the sun-screening index of the sun-screening product added with the physical sun-screening agent is effectively improved. The surface modified pearl powder has good compatibility in a sun-proof product system added with a physical sun-proof agent, and can keep the activity efficacy of pearls.
With reference to the first aspect, in a first possible example of the first aspect of the present application, the above surface-modified pearl powder is lauroyl lysine surface-modified pearl powder or triethoxy octyl silane surface-modified pearl powder.
With reference to the first aspect, in a second possible example of the first aspect of the present application, the above-mentioned surface-modified pearl powder is lauroyl lysine surface-modified pearl powder, and the lauroyl lysine surface-modified pearl powder is composed of 95 to 99wt% of pearl powder and 1 to 5wt% of lauroyl lysine.
Alternatively, the particle size of lauroyl lysine surface modified pearl powder is 5-10 μm.
Alternatively, lauroyl lysine surface-modified pearl powder is prepared by the following method:
mixing the pearl powder water solution with pH of 11.5-12.5 and lauroyl lysine powder to obtain a first mixed solution, preserving heat of the first mixed solution at 70-90 ℃ for 20-40 min to obtain a second mixed solution, regulating the pH value of the second mixed solution to 5.5-6.5, and continuously preserving heat at 70-90 ℃ for 20-40 min while stirring.
Optionally, the mass percent of the pearl powder in the pearl powder aqueous solution is 10-15 wt%.
In the above examples, the lauroyl lysine surface-modified pearl powder prepared by the above method is stable, and can achieve better compatibility with physical sunscreens, and increase the sun protection factor of the prepared sunscreens.
In combination with the first aspect, in a third possible example of the first aspect of the present application, the above surface-modified pearl powder is a triethoxy octyl silane surface-modified pearl powder, the triethoxy octyl silane surface-modified pearl powder being composed of 97 to 99.6wt% of pearl powder and 0.4 to 3wt% of triethoxy octyl silane.
Optionally, the particle size of the triethoxy octyl silane surface modified pearl powder is 1-5 mu m.
Alternatively, the triethoxy octyl silane surface modified pearl powder is prepared by the following method:
spraying ethanol solution of triethoxy octyl silane on the surface of pearl powder under stirring, stirring and drying.
Alternatively, the mass percent of triethoxy octyl silane in the ethanol solution of triethoxy octyl silane is 20 to 40 weight percent.
In the above examples, the triethoxy octyl silane surface modified pearl powder prepared by the above method is stable, and can achieve better compatibility with physical sunscreens and increase the sun protection index of the prepared sunscreens.
In a fourth possible example of the first aspect of the present application, in combination with the first aspect, the above-mentioned physical sunscreens comprise an oily dispersion of zinc oxide and/or an oily dispersion of titanium dioxide.
Alternatively, the physical sunscreens consist of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide.
Alternatively, the physical sun-screening agent consists of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide in a mass ratio of 1:2.
In combination with the first aspect, in a fifth possible example of the first aspect of the present application, the above-described sunscreen composition further comprises 2 to 7wt% of an emulsifier, 5 to 15wt% of an emollient, 0.2 to 2wt% of a film former, 5 to 15wt% of a humectant, 0.2 to 0.5wt% of a preservative, and the balance water.
With reference to the first aspect, in a sixth possible example of the first aspect of the present application, the emulsifier includes any one or more of lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, PEG-10 polydimethylsiloxane, polydimethylsiloxane PEG-10/15 crosslinked polymer, sorbitan olive oleate, cetyl PEG/PPG-10/1 polydimethylsiloxane, sorbitan sesquioleate, polyglyceryl-3 diisostearate, polyglyceryl-6 polyhydroxystearate, and polyglyceryl-4 diisostearate.
Emollients include any one or more of cyclopentadimethicone, caprylic/capric triglyceride, dioctyl carbonate, and coco-caprylate/caprate.
The film forming agent comprises any one or more of acrylic acid (ester)/polydimethylsiloxane copolymer and VP/eicosene copolymer.
The humectant comprises any one or more of glycerol, butanediol and 1, 3-propylene glycol.
The preservative comprises any one or more of phenoxyethanol, p-hydroxyacetophenone and methylparaben.
In combination with the first aspect, in a seventh possible example of the first aspect of the present application, the above-mentioned sunscreen composition further comprises 1 to 5wt% of a skin feel modifier, 0.2 to 5wt% of a thickener, 0.01 to 0.1wt% of a chelating agent, 0.5 to 2wt% of an emulsion stabilizer, and 0.1 to 2wt% of a skin protectant.
In the above examples, the sunscreen composition of the present application can produce a sunscreen agent having high-efficiency sunscreen effect, and also having the effects of whitening, removing spots, improving brightness and lubrication, and refreshing skin feel.
With reference to the first aspect, in an eighth possible example of the first aspect of the present application, the above-mentioned skin feel modifier includes silica and/or HDI/trimethylol hexyl lactone crosslinked polymer.
The thickener comprises any one or more of disteardimonium hectorite, dextrin palmitate, and dimethyl silyl silica.
The chelating agent includes disodium EDTA.
The emulsion stabilizer comprises sodium chloride and/or magnesium sulfate.
The skin protectant comprises bisabolol and/or rhizoma Zingiberis recens extract.
In a second aspect, the present examples provide a sunscreen comprising the above-described sunscreen composition.
In the technical scheme, the sunscreen agent system is stable, and has good sunscreen, whitening, freckle removing and brightening effects.
Detailed Description
Embodiments of the present application will be described in detail below with reference to examples, but it will be understood by those skilled in the art that the following examples are only for illustration of the present application and should not be construed as limiting the scope of the present application. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
The following is a specific description of a sunscreen composition and sunscreen agent according to embodiments of the present application:
the present application provides a sunscreen composition comprising: 0.5-5 wt% of surface modified pearl powder and 15-45 wt% of physical sun-screening agent.
The contact angle of the surface modified pearl powder is 100-140 degrees.
Optionally, the surface modified pearl powder is lauroyl lysine surface modified pearl powder or triethoxy octyl silane surface modified pearl powder.
The particle size of the surface modified pearl powder is 1-10 mu m.
The particle size of the unmodified pearl powder is 0.1-2.5 mu m.
Optionally, the particle size of the unmodified pearl powder is 0.3-2.5 mu m.
Optionally, the surface modified pearl powder is lauroyl lysine surface modified pearl powder.
The lauroyl lysine surface modified pearl powder consists of 95-99 wt% of pearl powder and 1-5 wt% of lauroyl lysine.
Alternatively, the particle size of lauroyl lysine surface modified pearl powder is 5-10 μm.
Lauroyl lysine surface modified pearl powder is prepared by the following method:
s1, dispersing unmodified pearl powder into deionized water to prepare an aqueous solution of pearl powder with the mass percentage of 10-15 wt%;
s2, adjusting the pH value of the water solution of the pearl powder to 11.5-12.5 by using a sodium hydroxide solution;
s3, mixing the water solution of the pearl powder with the pH value adjusted with lauroyl lysine powder according to a proportion to prepare a first mixed solution;
s4, preserving heat of the first mixed solution at 70-90 ℃ for 20-40 min to obtain a second mixed solution;
s5, regulating the pH value of the second mixed solution to 5.5-6.5 by sulfuric acid;
s6, maintaining stirring and heat preservation for 20-40 min at 70-90 ℃ of the second mixed solution after the pH value is regulated to obtain a third mixed solution;
s7, washing, drying and crushing the third mixed solution to obtain lauroyl lysine surface modified pearl powder.
Optionally, the pH of the aqueous solution of pearl powder is adjusted to 12 with sodium hydroxide solution.
Optionally, the first mixed solution is incubated at 80℃for 30min.
Optionally, the pH of the second mixture is adjusted to 6 with sulfuric acid.
Optionally, the second mixed solution after the pH value is adjusted is kept stirring and heat-preserving for 30min at 80 ℃.
Optionally, the surface modified pearl powder is triethoxy octyl silane surface modified pearl powder.
The triethoxy octyl silane surface modified pearl powder consists of 97-99.6 wt% of pearl powder and 0.4-3 wt% of triethoxy octyl silane.
Optionally, the particle size of the triethoxy octyl silane surface modified pearl powder is 1-5 mu m.
The triethoxy octyl silane surface modified pearl powder is prepared by the following method:
s1, mixing triethoxy octyl silane and ethanol according to the proportion of 2-4:6-8 to prepare an ethanol solution of the triethoxy octyl silane;
s2, adding unmodified pearl powder into a high-speed stirrer, spraying the prepared ethanol solution of triethoxy octyl silane into the high-speed stirrer through an oil spraying tank under high-speed stirring, so that the ethanol solution of triethoxy octyl silane and the unmodified pearl powder are fully stirred and uniformly mixed;
s3, discharging the prepared powder, placing the powder in an oven, baking the powder for 4 hours at 70-105 ℃, and naturally cooling the powder to obtain the triethoxy octyl silane surface modified pearl powder.
The ethanol solution of the triethoxycyclopedia is prepared and used immediately.
Physical sunscreens include oily dispersions of zinc oxide and/or oily dispersions of titanium dioxide.
Alternatively, the physical sunscreens consist of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide.
Alternatively, the physical sun-screening agent consists of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide in a mass ratio of 1:2.
Zinc oxide and titanium dioxide are used as two common physical sunscreens, are insoluble in water, are easy to whiten, are unevenly distributed and are easy to transmit light, and can only be solved by superposition coating, but the superposition coating is easy to cause false white and unnatural dressing.
The sun-proof composition comprises pearl powder, the pearl is a classical beauty medicinal material since ancient times, the medical macroscopical huge records of the historical generation such as the 'materia medica outline' and the 'Kaibao grass and wood' indicate that the pearl has the effects of tranquillizing, detoxifying, retaining youthful looks, moistening and tendering skin and the like, the skin is glossy and white, the beauty mechanism is that the pearl contains various amino acids and microelements required by human bodies, the nutrition components of the pearl are close to the nutrients required by human skin, the pearl is easy to be absorbed by the human bodies, and the pearl has good beauty and health care effects. Pearl powder processed from pearl is one of the most common ways to apply pearl cosmetology.
The inventor finds that the pearl powder has good isolation protection and anti-radiation effects, and the fine solid particles of the pearl powder can absorb and reflect a part of ultraviolet rays and various radiation rays, have a protective effect on radiation ray damage, can avoid sunburn formation, and have a good sun-proof effect, thereby delaying skin aging. In addition, the pearl powder can reduce the content of Malondialdehyde (MDA) which is a lipid peroxide degradation product, improve the activity of superoxide dismutase (SOD), inhibit the lipid peroxidation of the biomembrane caused by free radicals, thereby achieving the effects of resisting oxidation, delaying aging and the like.
The pearl powder is widely accepted as an anti-aging and whitening functional component in cosmetics, but has the defects of strong ionic property and easy agglomeration, and has poor compatibility in a common system.
Meanwhile, the inventor also finds that different particle sizes of the substances have a certain influence on the action and efficacy of the substances. For pearl powder, the particle size of the pearl powder added into the sun-screening composition is too large, so that the film forming property of the composition is affected, and the sun-screening index and sun-screening performance of the prepared sun-screening agent are affected; too small particle size is easy to agglomerate, easy to block pores to form a safety problem, and has a certain influence on the stability of a system after being added.
Therefore, a modification treatment is required to solve such problems. The pearl powder is mainly composed of calcium carbonate, the surface of the pearl powder is provided with a plurality of hydrophilic hydroxyl groups, and lauroyl lysine or triethoxy octyl silane is used for carrying out surface coating modification on the pearl powder. Not only the calcium carbonate and microelements contained in the pearl powder are in a closed space, but also the condensation of hydroxyl and water molecules is reduced, and the formation of hard agglomerates is lightened; meanwhile, as lauroyl lysine/triethoxy octyl silane is coated on the surface, steric hindrance repulsive force is generated, and the pearl powder aggregation is shielded. Improving the dispersibility of the water-based emulsion in a cosmetic system and avoiding damage to the system. The surface of the pearl powder is also enabled to present the lipophilicity of the coating material, so that the pearl powder can be better applied to a cosmetic system, and the compatibility with other substances is improved.
The surface modified pearl powder with proper particle size is selected to be compounded with the physical sun-screening agent, so that the sun-screening index of the sun-screening product added with the physical sun-screening agent is effectively improved. The surface modified pearl powder has good compatibility in a sun-proof product system added with a physical sun-proof agent, and can keep the activity efficacy of pearls. And on the premise of synergistically improving the sun-screening effect of the sun-screening product added with the physical sun-screening agent, the effects of whitening, removing freckles, improving brightness and lubricating can be achieved, and the prepared sun-screening product is fresh, cool, mild and free of irritation. Meanwhile, in order to prepare a sun-screening product with the same sun-screening effect, the addition proportion of the physical sun-screening agent is reduced, the use feeling of the formula is improved, and the safety of the formula is further enhanced.
The sunscreen composition further comprises 2 to 7wt% of an emulsifier, 5 to 15wt% of an emollient, 0.2 to 2wt% of a film former, 5 to 15wt% of a humectant, 0.2 to 0.5wt% of a preservative, and the balance water.
The emulsifier comprises one or more of lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, PEG-10 polydimethylsiloxane, polydimethylsiloxane PEG-10/15 crosslinked polymer, sorbitan olive oleate, cetyl PEG/PPG-10/1 polydimethylsiloxane, sorbitan sesquioleate, polyglyceryl-3 diisostearate, polyglyceryl-6 polyhydroxystearate and polyglyceryl-4 diisostearate.
Emollients include any one or more of cyclopentadimethicone, caprylic/capric triglyceride, dioctyl carbonate, and coco-caprylate/caprate.
The film forming agent comprises any one or more of acrylic acid (ester)/polydimethylsiloxane copolymer and VP/eicosene copolymer.
The humectant comprises any one or more of glycerol, butanediol and 1, 3-propylene glycol.
The preservative comprises any one or more of phenoxyethanol, p-hydroxyacetophenone and methylparaben.
Optionally, the sunscreen composition further comprises 1 to 5wt% of a skin feel modifier, 0.2 to 5wt% of a thickener, 0.01 to 0.1wt% of a chelating agent, 0.5 to 2wt% of an emulsion stabilizer, and 0.1 to 2wt% of a skin protectant.
Skin feel modifiers include silica and/or HDI/trimethylol hexyl lactone crosslinked polymers.
The thickener comprises any one or more of disteardimonium hectorite, dextrin palmitate, and dimethyl silyl silica.
The chelating agent includes disodium EDTA.
The emulsion stabilizer comprises sodium chloride and/or magnesium sulfate.
The skin protectant comprises bisabolol and/or rhizoma Zingiberis recens (ZINGIBER OFFICINALE) root extract.
The present application also provides a sunscreen comprising the above-described sunscreen composition.
The sun-screening agent system is stable, and has good sun-screening, whitening, freckle-removing and brightening effects.
The sunscreen agent is prepared by the following method:
mixing 0.5-5 parts by weight of surface modified pearl powder, 15-45 parts by weight of physical sun-screening agent, 2-7 parts by weight of emulsifying agent, 1-5 parts by weight of skin feel regulator, 0.2-5 parts by weight of thickening agent, 5-15 parts by weight of emollient and 0.2-2 parts by weight of film forming agent to prepare a first mixture, heating the first mixture to 75-80 ℃, and uniformly mixing to obtain a phase A component;
mixing 5-15 parts by weight of humectant, 0.5-2 parts by weight of emulsion stabilizer, 0.01-0.1 part by weight of chelating agent and water to prepare a second mixture, heating the second mixture to 75-80 ℃, and uniformly mixing to obtain a B phase component;
slowly adding the B phase component into the A phase component, simultaneously stirring rapidly, controlling the adding process to be 30-35 min, homogenizing for 3min by using a homogenizer after all the adding is finished, and cooling to 40-45 ℃ to obtain a third mixture;
and adding 0.1-2 parts by weight of skin protectant and 0.2-0.5 part by weight of preservative into the third mixture, continuously stirring until the mixture is completely cooled, and discharging to prepare the sun-screening agent.
The total weight of all the raw materials is 100 parts.
A sunscreen composition and sunscreen agent of the present application are described in further detail below in conjunction with the examples.
Example 1
The embodiment of the application provides a sunscreen composition and a sunscreen agent, wherein the formula of the sunscreen composition is shown in table 1.
Table 1 formulation of the sunscreen composition of example 1
Wherein, the particle diameter of the unmodified pearl powder is 0.3-2.5 mu m, the particle diameter of the lauroyl lysine surface modified pearl powder is 5-10 mu m, and the contact angle of the lauroyl lysine surface modified pearl powder is 100-140 degrees.
The sun-screening agent is prepared by the following steps:
mixing the raw materials of the phase A, heating to 75 ℃, and uniformly mixing to obtain a phase A component; mixing the raw materials of the phase B, heating to 75 ℃, and uniformly mixing to obtain a phase B component; slowly adding the B phase component into the A phase component, simultaneously stirring rapidly, controlling the adding process to be 30min, homogenizing for 3min by using a homogenizer after all the adding processes are finished, and cooling to 40 ℃ to obtain a third mixture; and adding various raw materials of the phase C into the third mixture, continuously stirring until the mixture is completely cooled, and discharging to obtain the sun-screening agent.
Example 2
The embodiment of the application provides a sunscreen composition and a sunscreen agent, wherein the formula of the sunscreen composition is shown in table 2.
Table 2 formulation of the sunscreen composition of example 2
Wherein the particle size of the unmodified pearl powder is 0.3-2.5 mu m, the particle size of the triethoxy octyl silane surface modified pearl powder is 1-5 mu m, and the contact angle of the triethoxy octyl silane surface modified pearl powder is 100-140 degrees.
The sun-screening agent is prepared by the following steps:
mixing the raw materials of the phase A, heating to 80 ℃, and uniformly mixing to obtain a phase A component; mixing the raw materials of the phase B, heating to 80 ℃, and uniformly mixing to obtain a phase B component; slowly adding the B phase component into the A phase component, simultaneously stirring rapidly, controlling the adding process at 35min, homogenizing for 3min by using a homogenizer after all adding is completed, and cooling to 45 ℃ to obtain a third mixture; and adding various raw materials of the phase C into the third mixture, continuously stirring until the mixture is completely cooled, and discharging to obtain the sun-screening agent.
Comparative example 1
Comparative examples of the present application provide a sunscreen composition and a sunscreen agent, the formulation of the sunscreen composition is shown in table 3.
Table 3 formulation of sunscreen composition of comparative example 1
The sun-screening agent is prepared by the following steps:
mixing the raw materials of the phase A, heating to 75 ℃, and uniformly mixing to obtain a phase A component; mixing the raw materials of the phase B, heating to 75 ℃, and uniformly mixing to obtain a phase B component; slowly adding the B phase component into the A phase component, simultaneously stirring rapidly, controlling the adding process to be 30min, homogenizing for 3min by using a homogenizer after all the adding processes are finished, and cooling to 40 ℃ to obtain a third mixture; and adding various raw materials of the phase C into the third mixture, continuously stirring until the mixture is completely cooled, and discharging to obtain the sun-screening agent.
Comparative example 2
Comparative examples of the present application provide a sunscreen composition and a sunscreen agent, the formulation of the sunscreen composition is shown in table 4.
Table 4 formulation of sunscreen composition of comparative example 2
Wherein the particle size of the unmodified pearl powder is 14-22 mu m, the particle size of the lauroyl lysine surface modified pearl powder is 18-45 mu m, and the contact angle of the lauroyl lysine surface modified pearl powder is 100-140 degrees.
The sun-screening agent is prepared by the following steps:
mixing the raw materials of the phase A, heating to 75 ℃, and uniformly mixing to obtain a phase A component; mixing the raw materials of the phase B, heating to 75 ℃, and uniformly mixing to obtain a phase B component; slowly adding the B phase component into the A phase component, simultaneously stirring rapidly, controlling the adding process to be 30min, homogenizing for 3min by using a homogenizer after all the adding processes are finished, and cooling to 40 ℃ to obtain a third mixture; and adding various raw materials of the phase C into the third mixture, continuously stirring until the mixture is completely cooled, and discharging to obtain the sun-screening agent.
Test example 1
The sunscreens of examples 1 to 2 and comparative examples 1 to 2 were subjected to a sunscreening performance test, the test instrument being a UV-2000S instrument, the test method being a COLIPA method, the test steps comprising: each sample was taken at 1.3mg/cm 2 Uniformly coating the mixture on a PMMA plate, coating 3 plates on each sample, standing for 15-20 min in a darkroom, and testing the SPF value and the UVAPF value in a UV-2000S instrument. After standing for one month, retesting was performed, and the test results are shown in table 5.
Table 5 results of sunscreen performance test of sunscreens of examples 1 to 2 and comparative examples 1 to 2
As is clear from the comparison between examples 1 to 2 and comparative example 1, the addition of the surface-modified pearl powder to the sunscreen agent can improve the sun protection factor of the sunscreen agent and improve the sun protection performance. And after standing for one month, retesting the sun-screening value of the sun-screening agent, the sun-screening agent added with the surface modified pearl powder still keeps higher sun-screening performance.
As is evident from the comparison of example 1 and comparative example 2, the selection of the surface-modified pearl powder having a particle size of 1 to 10 μm is advantageous for improving the sun-screening performance of the sun-screening agent.
Test example 2
The sunscreens of examples 1-2 were tested for stability, including heat, cold, alternating and lightAnd (5) testing. Wherein, the heat-resistant test conditions are: constant temperature and light shielding at 45+/-1 ℃; the cold resistance test conditions are as follows: -20+/-1 ℃ and keeping the temperature away from light; the alternating test conditions were: constant temperature of-20 ℃ for 3.5 days, constant temperature of 45 ℃ for 3.5 days and light shielding; the illumination test conditions are as follows: illumination constant temperature and humidity test box (1.47 x 10) 6 Lux hr), and the test results are shown in table 6.
TABLE 6 stability test results for sunscreens of examples 1-2
| Project | Heat resistant | Cold-resistant | Alternating | Illumination of |
| Example 1 | No abnormality | No abnormality | No abnormality | No abnormality |
| Example 2 | No abnormality | No abnormality | No abnormality | No abnormality |
As can be seen from Table 6, the sunscreen agent of the examples of the present application has excellent stability, and the compatibility and stability of the surface-modified pearl powder in the sunscreen agent are good.
The foregoing is merely a specific embodiment of the present application and is not intended to limit the present application, and various modifications and variations may be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application should be included in the protection scope of the present application.
Claims (16)
1. A sunscreen composition, wherein the sunscreen composition comprises: 0.5-5wt% of surface modified pearl powder and 15-45wt% of physical sun-screening agent;
the contact angle of the surface modified pearl powder is 100-140 degrees;
the particle size of the surface modified pearl powder is 1-10 mu m;
the surface modified pearl powder is lauroyl lysine surface modified pearl powder or triethoxy octyl silane surface modified pearl powder;
the physical sunscreens are selected from oily dispersions of zinc oxide and/or oily dispersions of titanium dioxide.
2. The sunscreen composition according to claim 1, wherein the surface modified pearl powder is lauroyl lysine surface modified pearl powder, the lauroyl lysine surface modified pearl powder consisting of 95-99 wt% pearl powder and 1-5 wt% lauroyl lysine.
3. The sunscreen composition according to claim 2, wherein the lauroyl lysine surface-modified pearl powder has a particle size of 5 to 10 μm.
4. The sunscreen composition according to claim 2, wherein said lauroyl lysine surface modified pearl powder is prepared by the following process:
mixing an aqueous solution of pearl powder with the pH value of 11.5-12.5 and lauroyl lysine powder to obtain a first mixed solution, preserving heat of the first mixed solution at 70-90 ℃ for 20-40 min to obtain a second mixed solution, adjusting the pH value of the second mixed solution to 5.5-6.5, and continuously preserving heat at 70-90 ℃ under stirring for 20-40 min.
5. The sunscreen composition according to claim 4, wherein the mass percentage of the pearl powder in the aqueous solution of the pearl powder is 10-15 wt%.
6. The sunscreen composition according to claim 1, wherein the surface modified pearl powder is triethoxy octyl silane surface modified pearl powder, the triethoxy octyl silane surface modified pearl powder consisting of 97 to 99.6wt% pearl powder and 0.4 to 3wt% triethoxy octyl silane.
7. The composition of claim 6, wherein the particle size of the triethoxycyclosilane surface modified pearl powder is 1-5 μm.
8. The sunscreen composition according to claim 6, wherein said triethoxy octyl silane surface modified pearl powder is prepared by the following method:
spraying ethanol solution of triethoxy octyl silane on the surface of pearl powder under stirring, stirring and drying.
9. The sunscreen composition according to claim 8, wherein the mass percentage of triethoxy octyl silane in the ethanol solution of triethoxy octyl silane is 20-40 wt%.
10. The sunscreen composition of claim 1, wherein the physical sunscreen consists of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide.
11. The sunscreen composition according to claim 1, wherein the physical sunscreen agent consists of an oily dispersion of zinc oxide and an oily dispersion of titanium dioxide in a mass ratio of 1:2.
12. The composition of any one of claims 1 to 11, wherein the composition further comprises 2 to 7wt% emulsifier, 5 to 15wt% emollient, 0.2 to 2wt% film former, 5 to 15wt% humectant, 0.2 to 0.3wt% preservative, and the balance water.
13. The sunscreen composition according to claim 12, wherein the emulsifier comprises any one or more of lauryl PEG-9 polydimethylsiloxane ethyl polydimethylsiloxane, PEG-10 polydimethylsiloxane, polydimethylsiloxane PEG-10/15 crosslinked polymer, sorbitan olive oleate, cetyl PEG/PPG-10/1 polydimethylsiloxane, sorbitan sesquioleate, polyglycerol-3 diisostearate, polyglycerol-6 polyhydroxystearate, and polyglycerol-4 diisostearate;
the emollient comprises any one or more of cyclopentamethylsilicone, caprylic/capric triglyceride, dioctyl carbonate and coco alcohol-caprylate/caprate;
the film forming agent comprises any one or more of acrylic acid (ester)/polydimethylsiloxane copolymer and VP/eicosene copolymer;
the humectant comprises any one or more of glycerol, butanediol and 1, 3-propanediol;
the preservative comprises any one or more of phenoxyethanol, p-hydroxyacetophenone and methylparaben.
14. The sunscreen composition according to claim 12, further comprising 1 to 5wt% of a skin feel modifier, 0.2 to 5wt% of a thickener, 0.01 to 0.1wt% of a chelating agent, 0.5 to 2wt% of an emulsion stabilizer, and 0.1 to 2wt% of a skin protectant.
15. The sunscreen composition according to claim 14, wherein said skin feel modifier comprises silica and/or HDI/trimethylol hexyl lactone crosslinked polymer;
the thickener comprises any one or more of disteardimonium hectorite, dextrin palmitate, and dimethyl silyl silica;
the chelating agent comprises disodium EDTA;
the emulsion stabilizer comprises sodium chloride and/or magnesium sulfate;
the skin protectant comprises bisabolol and/or rhizoma Zingiberis recens extract.
16. A sunscreen comprising the sunscreen composition of any one of claims 1 to 15.
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Denomination of invention: A sunscreen composition and sunscreen agent Granted publication date: 20240126 Pledgee: Agricultural Bank of China Limited Deqing County sub branch Pledgor: OSMUN BIOLOGICAL Co.,Ltd. Registration number: Y2024980023335 |