KR102009945B1

KR102009945B1 - Moisturizing cosmetic composition

Info

Publication number: KR102009945B1
Application number: KR1020160162961A
Authority: KR
Inventors: 이슬기; 이의정; 정민우; 최승만
Original assignee: 주식회사 엘지생활건강
Priority date: 2016-12-01
Filing date: 2016-12-01
Publication date: 2019-08-12
Also published as: KR20180062830A

Abstract

The present invention relates to a cosmetic composition having a skin moisturizing effect, specifically, by containing a mixture of thorn bamboo sap and grapevine sap as an active ingredient has excellent water retention ability and water retention effect has excellent side effects when applied to the human body excellent skin moisturizing ability in a dry environment It relates to a skin moisturizing cosmetic composition.

Description

Moisturizing cosmetic composition

The present invention relates to a cosmetic composition having a skin moisturizing effect, and in particular, by containing a mixture of thorn bamboo sap and grapevine sap as an active ingredient has excellent moisture retention and moisture retention effect, side effects when applied to the human body excellent in skin moisturizing ability in a dry environment It relates to a cosmetic composition for moisturizing the skin.

The stratum corneum layer contains a hydrophilic, water-retaining substance called Natural Moisturizing Factor (NMF), which helps the skin to maintain flexibility and maintain proper moisture. However, when the moisture content of the stratum corneum is less than 10%, the skin becomes rough and the body loses its protective function, causing aging. For example, in the case of dry skin, the aggregation of keratinocytes is weakened and scaling phenomenon occurs in which the keratinocytes are peeled off from the surface of the skin like scales. The dry skin is because the moisture content of the keratinocyte layer is less than the normal skin. In addition, due to changes in the environment or changes in life patterns, various stresses and environmental pollution caused by social life, frequent skin washing due to makeup habits and natural skin aging due to age increase, moisture in the stratum corneum decreases and the skin becomes dry. As the surface becomes rough, the skin loses its luster and dull appearance occurs, and the problem regarding skin moisturization is becoming more and more important.

As a conventional moisturizer to properly maintain the moisture content of the stratum corneum of the skin, humectants or NMF ingredients that absorb moisture, or natural water-soluble ingredients containing these ingredients are combined with or surround the water to It helps to stay. Examples of the humectants include polyols such as glycerin, sorbitol, propylene glycol, dipropylene glycol, and 1,3-butylene glycol. They exhibit excellent moisturizing properties when applied to the skin, but can be very sticky or unpleasant due to the inherent viscosity and physical properties of polyols.

Another method is to increase the water retention in the stratum corneum by using an occlusive moisturizer that prevents evaporation of water. As a closed moisturizer, a lipid component such as oil or wax is used. By forming an oil film on the skin to suppress evaporation of moisture, the moisturizing effect is maintained, but in terms of feeling, the absorption is slowed, and negative effects such as stickiness and shine are likely to occur at the same time.

In addition, NMF components such as sodium pyrrolidone carboxylate (PCA-Na), sodium lactate (urea), urea, or natural water-soluble components containing these components are highly electrolytic and difficult to maintain stability in the formulation. As a result, raw materials extracted from natural products have little effect or many problems such as stability in the formulation and side effects caused by skin irritation have been actively studied to use natural extracts that are not harmful to the human body.

On the other hand, the thorn tree (Bambusa Arundinacea) is a perennial evergreen tree belonging to the family of bamboo, and the hollow stem grows out of the thick rhizome. Distributed in tropical India and most of Pakistan, it is widespread in temperate and humid temperate regions, but thrives in frost-free conditions and grows up to 1000 meters in southern India.

Among the various kinds of bamboo, the fibers and pulp of thorn bamboo are mainly used to make paper products, and the stem is mainly composed of cellulose, hemicellulose and lignans, and contains a small amount of resin. Bamboo is used for cooking like bamboo shoots, but bamboo as an herbal medicine is particularly effective as an antipyretic to reduce heat. In particular, recently, studies on the antioxidant and anticancer effects of bamboo salt have been actively conducted (Korean Patent Publication No. 10-20160035522), and the anticancer effect of bamboo powder itself has been reported (Japanese Patent No. 3497362).

Grape vine is a perennial deciduous tree of the vine family and has all-round nature with its tree-like properties extending into the vines. In Korea, it has been used the name "Muru" or "Merwi" since ancient times, and the name of grape is known to originate from the native language of Central Asia, the origin of European species. The grape family is very diverse in variety, especially about 10 genera and 500 species are distributed in the tropics, and 4 genera and 6 species are distributed in Korea and most of them are trees with tendrils.

The vines form snow on every well-developed yearly branch, and the next branch grows in the next year, and the fruit grows on the branch. Due to the nature of the plant that withstands heat and deeply roots, it is a fruit that grows well in most wilderness areas or sloping mountains and grows in adverse conditions such as hot and dry climates and mountainous areas. By the effect of grapes, the fruit shed blood, strengthen the musculature, urine well, roots and vines were used for the treatment of quadriplegia due to stroke (Chinese Herbal Book).

Under these backgrounds, the inventors of the present invention confirmed that the thorny bamboo sap and grapevine sap mixture exhibited excellent moisture retention and high moisture retention while searching for an ingredient having a skin moisturizing effect, thereby completing the present invention.

Korean Patent Publication No. 10-1558185 Korean Patent Publication No. 10-0878331

An object of the present invention is to provide a cosmetic composition containing a mixture of thorn bamboo sap and grapevine sap as an active ingredient.

Another object of the present invention to provide an external composition for skin comprising the cosmetic composition.

One aspect for achieving the object of the present invention provides a cosmetic composition containing a mixture of thorn bamboo sap and grapevine sap as an active ingredient.

Specifically, the present invention provides a skin moisturizing cosmetic composition having a high moisture retention ability and water retention ability by containing a mixture of thorn bamboo sap and grapevine sap as an active ingredient.

In the present invention, the “thorny tree” is a perennial tree belonging to the family of bamboos, and is spread far to tropical, subtropical and temperate regions, and thrives maximally in frost-free conditions. In addition, "thorn sap" refers to the sap collected from the thorn bamboo, the present invention is not limited to this, but after collecting the thorn bamboo sap after the first filtration process, diluted with ultrapure water at low temperature The supernatant after the precipitation can be used again by a second filtration process.

In the present invention, "vine" is a perennial deciduous broad-leaved tree of the vine family with a tree-like property that extends to the vines, the variety is very diverse and 4 genus 6 species are distributed in Korea. In addition, "vine grape sap" refers to the sap collected from the grape vine, the present invention is not limited thereto, but after the vine sap collected through the first filtration process, diluted with ultrapure water and at a low temperature The supernatant after the precipitation can be used again by a second filtration process.

In the present invention, the thorn bamboo sap and grapevine sap mixture may specifically include 0.01 wt% to 30 wt%, and more specifically 0.1 wt% to 10 wt%, based on the total weight of the cosmetic composition. It is not limited to this. In the present invention, the mixture is a mixture of thorn bamboo sap and grape vine sap, the mixing ratio of thorn bamboo sap: grape vine sap may be 10 to 60 parts by weight: 10 to 60 parts by weight, but is not limited thereto. It is not that.

In one embodiment of the present invention, the thorny bamboo sap and grapevine sap inhabiting in Korea was used, and when the mixture of the thorny sap and grapevine sap is contained, the synergy of these components in the case of containing the sap, respectively As a result, the moisture retention ability was increased, and according to the result of mixing in a ratio of 1: 1, it was confirmed that the moisturizing effect was greatly improved (Table 1 and Table 2).

In the present invention, the content of the thorn bamboo sap and grapevine sap mixture may be specifically 0.01 to 30% by weight, more specifically 0.1 to 10% by weight, but is not limited thereto. In this case, when the mixture is less than 0.01% by weight, the effect of use cannot be obtained, and when the mixture exceeds 30% by weight, it is difficult to apply it to various forms of formulations due to the reduction in stability such as discoloration of the product, and the cost-effectiveness may be uneconomical. .

In the present invention, "skin moisturizing" means to increase the moisture on the skin and to maintain a moist state. By applying the cosmetic composition according to the present invention on the skin can increase the water retention capacity and water retention ability of the skin.

In one embodiment of the present invention, the skin moisture content measuring device corneometer (CM825, Corage & Khazaka, Germany) using a cosmetic composition comprising the mixture as an active ingredient to the skin, as a result of significantly increased water retention for 24 hours Also, by confirming that the moisture is maintained even after washing, it was confirmed that the cosmetic composition comprising the mixture of the thorn bamboo sap and grapevine sap of the present invention can be used for skin moisturizing purposes (Table 2 and Table 3).

The cosmetic composition according to the present invention is a solution, external ointment, cream, foam, nourishing lotion, softening lotion, pack, softening water, latex, makeup base, essence, soap, liquid cleansing agent, bath, sunscreen cream, sun oil, suspension, Formulations selected from the group consisting of emulsions, pastes, gels, lotions, powders, soaps, surfactant-containing cleansing, oils, powder foundations, emulsion foundations, wax foundations, patches and sprays, in particular solubilizing formulations or gel creams. It may be prepared, but is not limited thereto.

In addition, the cosmetic composition of the present invention may further include one or more cosmetically acceptable carriers formulated in general skin cosmetics, and as conventional components, for example, oil, water, surfactants, moisturizers, lower alcohols, Thickeners, chelating agents, pigments, preservatives, flavoring agents, and the like may be appropriately blended, but are not limited thereto.

The cosmetically acceptable carrier included in the cosmetic composition of the present invention varies depending on the dosage form.

When the formulation of the present invention is an ointment, paste, cream or gel, the carrier component may be animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide or Mixtures of these may be used.

If the formulation of the invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, polyamide powder or mixtures thereof may be used, in particular in the case of a spray additionally chloro Propellants, such as fluorohydrocarbons, propane / butane or dimethyl ether.

When the formulation of the present invention is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspending agents such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, micro Crystalline cellulose, aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

When the formulation of the present invention is a soap, alkali metal salts of fatty acids, fatty acid hemiester salts, fatty acid protein hydrolyzates, isethionates, lanolin derivatives, aliphatic alcohols, vegetable oils, glycerol, sugars and the like may be used as carrier components. Can be.

Another aspect of the present invention provides a skin external preparation composition for moisturizing skin comprising a mixture of thorny bamboo sap and grapevine sap.

In the present invention, "thorns", "thorns sap", "vines", "vines sap", and "skin moisturizing" are as described above.

In the present invention, the "external preparation" is a formulation provided for external use, such as external preparations, external preparations, external preparations, ointments, warning agents, suppositories. External preparation means dispersing in zinc starch, erosion of skin mucosa, ulcer, etc.External tablet means dissolving tablet or vaginal tablet, and external preparation is water, ethanol, oil, etc. It is used as a liquid preparation, and it is used for brushing teeth, wet compresses, washing with water, spraying, and nasal drops. In addition, ointment is a semi-solid agent of moderate roughness applied to the skin, the warning is a skin application that softens to room temperature solids, body temperature, suppositories are applied to the anal, vagina, urethra.

The "skin external preparation" refers to a formulation that acts on the external skin of the external preparation, and in the present invention, it means a skin external preparation having an excellent effect on skin moisturizing by containing the cosmetic composition as an active ingredient. Specifically, the external preparation for skin may be prepared as a drug or quasi-drug in the form of an external preparation for cream, gel, patch, spray, ointment, warning, lotion, linen, pasta, or cataplasma, but is not limited thereto. Do not.

The present invention by preparing a cosmetic composition containing one or a mixture thereof selected from thorny bamboo sap and grapevine sap as an active ingredient, the moisture retention ability and water retention is increased, the skin moisturizing effect is very excellent hypoallergenic skin moisturizing A cosmetic composition for use can be provided.

Hereinafter, specific examples are provided to help understanding of the present invention, but the following examples are merely to illustrate the present invention, and the scope of the present invention is not limited to the following examples.

Production Example One: Spiny Bamboo Sap And Grapevine sap Ready

The spiny bamboo sap and grapevine sap used in the present invention are prepared through two filtration steps in the order of 1 μm and 0.5 μm after desorption and deodorization after collecting sap. After diluting the ratio of 5 kg of ultrapure water to 1 kg of sap, the precipitate was processed at low temperature, followed by three further filtration steps in the order of 1.0 μm, 0.3 μm, and 0.2 μm, and used in subsequent experiments.

Production Example 2: Spiny Bamboo Sap And Grapevine sap Containing Emulsion Produce

The emulsion compositions of Examples 1-2 and Comparative Examples 1-4 were prepared by stirring the contents and components shown in Table 1 in a mixer mixer tank and uniformly mixing them through heating, degassing and cooling. Example 1 and Example 2 were mixed in the ratio of the thorn bamboo sap: grapevine sap, Comparative Examples 1 and 2 included the thorn bamboo sap and grapevine sap respectively. In addition, Comparative Examples 3 and 4 contained glycerin and butylene glycol, which are used as conventional moisturizing agents, alone.

Raw material name Example
(weight%) Comparative example
(weight%) One 2 One 2 3 4 Cetyl alcohol One One One One One One Bees wax 0.5 0.5 0.5 0.5 0.5 0.5 CAPRYLIC / CAPRIC TRIGLYCERIDE 5 5 5 5 5 5 Aracel-165 One One One One One One Tween-60 2 2 2 2 2 2 Purified water To 100 To 100 To 100 To 100 To 100 To 100 Carbomer 0.2 0.2 0.2 0.2 0.2 0.2 Triethanolamine 0.12 0.12 0.12 0.12 0.12 0.12 EDTA-3Na Quantity Quantity Quantity Quantity Quantity Quantity antiseptic Quantity Quantity Quantity Quantity Quantity Quantity Spices Quantity Quantity Quantity Quantity Quantity Quantity Spiny Bamboo Sap 5 7 10 - - - Grapevine sap 5 3 - 10 - - glycerin - - - - 5 - Butylene Glycol - - - - - 5

Experimental Example One: Moisturizing Evaluation experiment

In order to evaluate and determine the skin moisturizing power of the compositions of the Examples and Comparative Examples, the emulsion compositions of Examples 1-2 and Comparative Examples 1-4 were used to quantitate 2 ul / cm ² on the forearm (horizontal, 1 cm in length). After application, the change in the water retention of the stratum corneum was measured to evaluate whether the effect on moisturizing power. The instrument used was a skin moisture content corneometer (CM825, Corage & Khazaka, Germany).

Specifically, the composition of each Example and Comparative Example in a constant temperature and humidity room of 22 ℃, 50% relative humidity, respectively, after applying a predetermined amount (2 ul / cm ² ) to the inside of the arm of 20 test subjects, and then tap lightly absorbed, then apply Moisturizing effect was evaluated by measuring the moisture increase rate (%) after 1, 3, 6, 24 hours based on the previous moisture content. Moisture increase rate (%) was used in Equation 1 below, the results obtained are shown in Table 2.

[Equation 1]

Measured value after sample application-Measured value before sample application

% Growth = ------------------------------------------- X 100

Measured value before sample application

division Example
Moisture growth rate (%) Comparative example
Moisture growth rate (%) One 2 One 2 3 4 Before application 0 0 0 0 0 0 1 hours 87.399 92.345 62.286 60.324 30.392 28.243 3 hours 68.966 85.421 50.276 51.383 25.344 22.421 6 hours 56.181 70.630 38.237 40.293 20.141 16.942 24 hours 39.928 52.329 25.348 32.132 11.233 7.023

As shown in Table 2, the initial moisturizing increase rate after application of Example 2 (thorny sap: grapevine sap = 7: 3) compared to Example 1 (visible sap: grapevine sap = 5: 5) of the present invention is Similarly, but as time passed, the moisturizing sustainability of Example 2 was excellent. Example 2 showed more than twice the moisturizing persistence compared to Comparative Example 1 or 2. In addition, when compared with Comparative Examples 3 or 4 used as a conventional moisturizing agent, it showed a moisturizing duration of at least 7 times for 24 hours after application.

Through the above results, the cosmetic composition comprising a mixture of thorny bamboo sap and grapevine sap according to the present invention as a mixed ratio of 7: 3 each as an active ingredient by confirming that not only the initial moisture increase rate but also maintains the moisture retention for a long time It was confirmed that it had an excellent effect as a skin moisturizing use excellent in moisture retention ability.

In addition, after 24 hours after application to check the water retention capacity, the application site was cleaned only with running water, and the moisture increase rate (%) compared to before application after 10 minutes and 40 minutes after cleaning was used in Equation 1 above. And the obtained results are shown in Table 3.

division Example
% Increase Comparative example
% Increase One 2 One 2 3 4 Before application 0 0 0 0 0 0 10 minutes after cleaning 26.666 39.543 22.378 21.432 4.213 3.128 40 minutes after cleaning 20.819 31.674 18.324 18.532 2.243 1.042

As shown in Table 3, it was confirmed that the mixture of Example 2 compared to Example 1 according to the present invention shows an excellent moisture increase rate. After 10 minutes of washing, the mixture of Example 2 showed an excellent moisture increase rate of up to about 2 times compared to Comparative Example 1 or 2, and about 1.7 times compared to the case of including a single component even after 40 minutes of washing. Excellent moisture growth rate was shown. Moreover, when compared with the glycerin and butylene glycol of the comparative examples 3 and 4 used as a conventional moisturizing agent, it showed the remarkably superior moisture increase rate.

From the above results, it can be seen that the cosmetic composition according to the present invention has a much higher water retention than the glycerin and butylene glycol-containing composition commonly used, Comparative Example 1 using only thorn bamboo sap or grapevine sap Or compared with 2, it was confirmed that the water retention capacity of Example 1 using the two kinds of the sap mixture.

Experimental Example 2: skin irritation evaluation experiment

In order to evaluate skin irritation of the cosmetic compositions of Examples 1-2 and Comparative Examples 1-4, a patch test was performed on 25 healthy adults and men and women.

Each sample was added to the pin chamber (approximately 0.2 g) and attached to the subject's skin for 24 hours to prevent loss of the sample using a filter paper of appropriate size. Stimulation degree and stimulation response were evaluated according to the criteria shown in Table 3 by the method of judging by two experts, calculated by the following equation, and the results are shown in Table 4.

Stimulus
(Score) Irritation
(Reaction) Criteria 0 - No symptoms One +- Have only slight erythema reactions 2 + Clear erythema, edema but no blisters 3 ++ Clear erythema, edema, blisters 4 +++ If you have a cannon

[Equation 2]

Number of subjects who responded

Skin irritation index = Irritation degree X -------------------------

Total number of subjects

sample Judgment result (the number of people) Skin irritation index ++ + +- - Example 1 0 0 One 24 0.04 Example 2 0 0 0 24 0.00 Comparative Example 1 0 0 One 24 0.04 Comparative Example 2 0 0 2 23 0.08 Comparative Example 3 0 0 2 23 0.08 Comparative Example 4 0 0 2 23 0.08

As shown in Table 4, through the skin irritation index of Example 1, it was confirmed that the cosmetic composition according to the present invention is a hypothermic moisturizing cosmetic composition having no side effects when applied to the human body.

As described above, as described in the above Examples and Experimental Examples, the present invention prepares a cosmetic composition containing a mixture of thorny bamboo sap and grapevine sap as an active ingredient and apply it to the skin, thereby retaining moisture retention and Increased moisture retention ability can provide a skin composition of hypoallergenic cosmetic composition with excellent skin moisturizing effect.

Claims

A cosmetic composition for moisturizing skin containing a mixture of thorn bamboo (Bambusa Arundinacea) sap and grape vine (grape vine) sap as an active ingredient.

delete

The cosmetic composition of claim 1, wherein the thorny bamboo sap and grapevine sap mixture is contained in an amount of 0.1% to 30% by weight based on the total weight of the cosmetic composition.

The cosmetic composition of claim 1, wherein the mixing ratio of the thorny bamboo sap: grapevine sap is 10 to 60 parts by weight: 10 to 60 parts by weight.

The cosmetic composition of claim 1, wherein the composition has a water retention capability for 24 hours after application.

The cosmetic composition according to claim 1, wherein the composition has a moisturizing ability even after washing.

The cosmetic composition according to claim 1, wherein the composition has water retention ability for 24 hours after application and cleaning after comparison with bramble sap.

The cosmetic composition of claim 1, wherein the composition has a water retention capability for 24 hours after application and cleaning after the grapevine solution.

According to claim 1, wherein the formulation of the skin moisturizing cosmetic composition is a solution, external ointment, cream, foam, nourishing longevity, softening longevity, pack, softening water, latex, makeup base, essence, soap, liquid cleansing agent, bath, sun Can be selected from the group consisting of screen creams, sun oils, suspensions, emulsions, pastes, gels, lotions, powders, soaps, surfactant-containing cleansing, oils, powder foundations, emulsion foundations, wax foundations, patches and sprays Cosmetic composition, which is applicable to a solubilized formulation or gel cream.

A skin external composition comprising the cosmetic composition according to any one of claims 1 and 3 to 9.