KR102006952B1 - Cosmetics compositions for prevention and improvement of wrinkle - Google Patents
Cosmetics compositions for prevention and improvement of wrinkle Download PDFInfo
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- KR102006952B1 KR102006952B1 KR1020130152354A KR20130152354A KR102006952B1 KR 102006952 B1 KR102006952 B1 KR 102006952B1 KR 1020130152354 A KR1020130152354 A KR 1020130152354A KR 20130152354 A KR20130152354 A KR 20130152354A KR 102006952 B1 KR102006952 B1 KR 102006952B1
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- wrinkle
- improving
- carbodiimide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
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Abstract
The present invention relates to a cosmetic composition for preventing and improving wrinkles.
The cosmetic composition for preventing and improving wrinkles according to the present invention contains a wrinkle preventing and improving component having a specific functional group capable of covalently bonding with a protein residue on the surface of the skin, thereby forming a covalent bond without damaging the skin to prevent permanent wrinkles and It provides an improvement effect.
Description
The present invention relates to a reactive wrinkle preventing and improving component and a cosmetic composition for preventing and improving wrinkles having a functional group binding to a protein.
Generally, the composition for preventing and improving wrinkles is applied to the skin for the purpose of preventing, restoring or healing wrinkles formed on human skin, especially the face part, to beautify, increase charm, and change appearance. It aims to use in a similar way to others, and it means that the action | action to a human body is slight.
In the case of quasi-drugs, it is defined that even if there is an action on the human body, the action is mild and is not used for the treatment or prevention of diseases, and does not have the purpose of use such as affecting the structure and function of the body.
Wrinkles are a classic example of signs of aging and preventing or improving their development is a big part of cosmetics, along with the wishes of many women. Kinds of aging and its symptoms are first caused by natural aging due to degenerative changes, resulting in thinning of the skin, smoothing and sagging of the epidermis and dermis, and photoaging caused by ultraviolet rays results in abnormal cell arrangement and cell polarity.
The factors involved in the development of wrinkles are known to be very diverse, such as sunlight, skin elastin, collagen, matrix, vascular disorders, free radicals, etc. The general method and principle of action to improve these wrinkles are vitamin C, vitamin A (retinoid) And peptides to increase collagen synthesis to promote cell regeneration and antioxidant activities such as vitamin E (tocopherol), flavonoids, polyphenols, SOD, coenzyme Q10, and alpha lipoic acid. The method of suppressing and the method of reducing muscle movement using the acetyl hexapeptide called a pseudo botox, etc. are used.
The cosmetic composition for preventing and improving wrinkles is generally a composition for anti-wrinkle and anti-wrinkle function for skin care, trimming and foundation, and a composition for preventing and improving wrinkles such as base and points, and for bathing, sun care, sun tanning, It contains compositions for preventing and restoring body wrinkles such as restriction, deodorization, hair loss, and hair removal.
Common raw materials used to construct the cosmetic composition for preventing and improving wrinkles include oily materials such as fats and oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, ester oils and silicone oils, anions, cations, amphoteric and nonionic compounds. It includes high molecular compounds used as surfactants, humectants, thickeners and film-forming agents, ultraviolet absorbers and blocking agents, antioxidants, metal ion blockers, colorants including dyes and pigments, flavoring agents, and preservatives.
In addition, anti-wrinkle and improvement functions to provide special performance, vitamin A (retinoid) and its derivatives, peptides, vitamin E (tocopherol) and its derivatives, flavonoids, polyphenols, SOD, coenzyme Q10, alpha lipoic acid, acetyl Wrinkle ingredients such as hexapeptide, retinol, retinyl palmitate, adenosine, vitamin C, collagen, hexapeptide3, EGF, kinetin, snail mucus, aquanomede, ceramide, glycerin, hyaluronic acid, betaine, chitosan, vitamin Moisturizing ingredients such as E (tocopherol), urea, and the like.
However, when used on the skin as a composition for preventing and improving wrinkles and for preventing and improving wrinkles, only a temporary effect is provided until the next cleaning after the treatment, and there is always the inconvenience of reprocessing after the cleaning.
Patent document 1 relates to a skin non-aqueous personal care product, and is a functional group capable of covalently bonding to protein residues on the hair or skin surface in a non-aqueous part, such as carbonate, aldehyde, propaldehydealdehyde, and butylaldehyde. (butylaldehyde), nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, Hydroxysuccinimidyl ester, imidazole, oxycarbonylamidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine (ethyleneimine), thioether, acrylonitrile, acrylic acid or methacrylic ester, disulfide (d isulfide), a ketone and a functional group represented by RX (R is any one selected from the group consisting of alkyl, aryl, aralkyl, ring and unsaturated ring, X is I, Br or Cl) Although it discloses a hair or skin personal care product comprising a conditioning component having any one or more, and separated into a non-aqueous part and an aqueous part, and mixed and used immediately before use, the various functional groups described above Targets lysine that is harmful to the human body or contains amino acids of the protein constituting the skin as small as skin keratin (3.1 to 6.9%), or hair (16.6 to 18%), skin keratin (2.3 to 3.8%) Since the target is reacted with cysteine, which is about), the reaction efficiency is lowered and there is a problem that each substance must be synthesized one by one.
An object of the present invention is to provide a cosmetic composition for preventing and improving wrinkles that can continuously give a semi-permanent wrinkle prevention and improvement effect without damaging the skin.
As a means for solving the above problems, the present invention provides a cosmetic composition for preventing and improving wrinkles comprising a carbodiimide-based compound and wrinkle prevention and improvement component.
As another means for solving the above problems, the present invention provides a carbodiimide, imido ester, aryl azide, diazirine, hydroxymethyl phosphine, pentafluorophenyl ester, pyridyl disulfide, Provides reactive wrinkle prevention and amelioration components that combine functional groups covalently bound to one or more hair or skin surfaces proteins selected from the group consisting of sulfo-hydroxysuccinimide esters, alkoxy amines, hydrazides, haloacetyls, and azides .
As another means for solving the above problems, the present invention provides a cosmetic composition for preventing and improving wrinkles comprising the reactive wrinkle prevention and improvement component.
The cosmetic composition for preventing and improving wrinkles according to the present invention contains a reactive wrinkle preventing and improving component and / or a carbodiimide-based compound incorporating a specific functional group capable of covalently bonding with protein residues of the skin, thereby covalently binding the skin without damage. It forms a semi-permanent skin wrinkle prevention and improvement effect.
The present invention relates to a cosmetic composition for preventing and improving wrinkles comprising a carbodiimide compound and a wrinkle preventing and improving component.
The cosmetic composition for preventing and improving wrinkles according to the present invention, for example, by reacting a carbodiimide-based compound with a known wrinkle preventing and improving component through a reactive wrinkle preventing and improving component having a carbodiimide group, a protein of the skin By forming a covalent bond with, wrinkle prevention and improvement effect can be maximized.
The carbodiimide-based compound may be included in an amount of 0.001 to 10% by weight, 0.01 to 7% by weight, or 0.1 to 5% by weight based on 100% by weight of the total cosmetic composition. If the content is less than 0.001% by weight, there is a problem in that continuous wrinkle prevention and improvement effects are difficult to be exhibited. If the content exceeds 10% by weight, the carbodiimide compound that is excessively present beyond the reaction site present on the skin does not react with the skin. There is a problem that can act as a component that does not help to improve the sustainability by reacting with the agonist in the state.
In the present invention, the "wrinkle prevention and improvement effect" means a function of preventing, restoring, or healing and beautifying wrinkles formed on the skin, especially the face part.
Wrinkle prevention and improvement components used in the present invention may include extracts derived from natural products such as copper, plants, minerals, amino acids, hormones, vitamins and the like, but is not limited thereto. For example, vitamin A (retinoid), vitamin E (tocopherol), flavonoids, polyphenols, SOD (Superoxide dismutase), coenzyme Q10, alpha-lipoic acid, acetylhexapeptide, retinol, retinyl palmitate, retinyl acetate, Group consisting of adenosine, vitamin C, collagen, hexapeptide3, skin cell growth factor (EGF), kinetin, snail mucus, aquanoid, ceramide, glycerin, hyaluronic acid, betaine, chitosan, urea and derivatives thereof It may be one or more selected from.
The wrinkle prevention and improvement component is preferably used in 0.001 to 50 parts by weight, 0.001 to 30 parts by weight, 0.01 to 10 parts by weight or 0.1 to 5 parts by weight based on 100 parts by weight of the total cosmetic composition. If the content thereof is less than 0.001 part by weight, there is a problem of effective performance limitation, and if it exceeds 50 parts by weight, there is a problem in formulation and formulation stabilization.
In particular, the wrinkle preventing and improving component in the present invention can increase the reaction efficiency with the carbodiimide-based compound by including a carboxyl group or an amine group in the molecule.
In addition, the anti-wrinkle and improvement component in the present invention may have a functional group capable of covalently bonded to protein residues on the skin surface.
The functional group covalently bonded with the protein is carbodiimide, imido ester, aryl azide, diazirine, hydroxymethyl phosphine, pentafluorophenylester, pyridyl disulfide, sulfo-hydroxysuccinimide ester, alkoxy amine, Hydrazide, haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, hydroxysuccinimidyl ester , Imidazole, oxycarbonyl amidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, acrylic acid or methacrylic acid ester, disulfide and ketone This is not restrictive.
In addition, the protein may include a reactive moiety of thiol, hydroxyl, carboxyl or amine.
The carbodiimide-based compound is a generic term for a compound containing a structure represented by the following formula (1) in a molecule.
[Formula 1]
-N = C = N-
The carbodiimide-based compound preferably includes at least 1 to 1000 structures of Formula 1, more preferably 1 to 100 structures represented by Formula 1 in a molecule, It is more preferable to include 1 to 10 structures represented in the molecule.
In this case, when the number of carbodiimide groups represented by the formula (1) in one molecule exceeds 1000, the viscosity of the raw material is too large, the molecular weight is too large, and the reaction sites that can react too much are excessively large, and The molecule | numerator which has a bodyimide group becomes so large that the problem which efficiency falls by covering the part which shows the functional effect of the molecule which has a substantial function arises.
Specific examples of the carbodiimide-based compound in the present invention may be a compound represented by the following formula (2), n is 4 and m is 11 in the formula (2) is benzene, 1,3, -bis (1- Isocyanato-1-methylethyl)-, homopolymer, polyethylene glycol mono-meth-ether-block (Benzene, 1,3-bis (1-isocyanato-1-methylethyl)-, homopolymer, polyethylene glycol mono- Me-ether-blocked) (hereinafter referred to as polymer type carbodiimide compound of Formula 2).
(2)
In Formula 2, n is 1 to 100, m is 1 to 100.
In another embodiment of the carbodiimide-based compound in the present invention, as a compound represented by the following formula (3), 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide (1-Ethyl-3- (3-dimethylaminopropyl) carbodiimide) or 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide HCl (1-Ethyl-3- (3-dimethylaminopropyl) carbodiimideHCl) can be used.
(3)
In a preferred embodiment of the cosmetic composition for preventing and improving wrinkles according to the present invention, a wrinkle preventing and improving component having a carboxyl group is made into a reactive ester wrinkle preventing and improving component having direct bioreactivity or skin keratin (15.5-23.5). Reactive esterification of amino acids (ex, aspartic acid, glutamic acid) present in excess of%) to prevent wrinkles and improve the wrinkles containing amine groups using carbodiimide-based compounds that can be targeted by reactive ester forms (reactive wrinkles prevention And the improvement component) to increase the reaction efficiency, thereby significantly increasing the effect. In addition, carbodiimides, imidoesters, arylazides, diazirines, hydroxymethyl phosphines, pentafluorophenylesters, pyridyl disulfides, sulfo-hydroxysuccinimide esters, alkoxy, which may target other amino acids The effect can be further enhanced by using an anti-wrinkle and improving component comprising a functional group such as amine, hydrazide, haloacetyl, azide in the molecule.
In a more preferred embodiment, the anti-wrinkle component of the anti-wrinkle and improvement component having a carboxyl group or the surface of the protein of the skin, or the 1-ethyl-3- (3-dimethylaminopropyl) carbodiimide Primary reaction of a carbodiimide-based compound such as hydrochloric acid (1-ethyl-3- (3-dimethylaminopropyl) carbodiimide.HCl) to form a reactive ester, preventing wrinkles having an amine in the molecule again with the formed reactive ester functional group An excellent wrinkle prevention and improvement effect can be obtained by reacting an improvement component or reacting with an amine on the skin surface. In the reaction, the reaction may be preferably performed at a pH of 2 to 10, more preferably at a pH of 3 to 9, and most preferably at a pH of 4 to 5 in an acidic to weakly acidic aqueous solution. The most reaction efficiency can be increased. The reaction is completed within 1 to 30 minutes.
In Scheme 1 below, a wrinkle preventing and improving component molecule having a carboxyl group was first reacted with a carbodiimide compound to form a reactive ester, followed by reaction with an amino acid of a living body having an amine residue to form a covalent bond. .
[Reaction Scheme 1]
In the following scheme 2, aspartic acid and glutamic acid, which are biological amino acids having a carboxyl group on the surface of the protein of the skin, are first reacted with a carbodiimide-based compound to form a reactive ester, followed by reaction with an anti-wrinkle and improvement component having an amine residue to thereby covalently bond. The reaction schematic to form is shown.
[Reaction Scheme 2]
The carbodiimide-based compound increases the reaction efficiency of the protein and wrinkle prevention and improvement component of the skin, so that the reactive wrinkle prevention and improvement component bound to the skin does not come off during normal cleaning by shampoo or soap and is almost permanent It can remain attached to the skin.
The present invention also provides carbodiimide groups, imidoesters, arylazides, diazirines, hydroxymethyl phosphines, pentafluorophenylesters, pyridyl disulfides, sulfo-hydroxysuccinimide esters in anti-wrinkle and improvement components. , Alkoxy amine, hydrazide, haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, hydroxy Selected from the group consisting of succinimidyl ester, imidazole, oxycarbonyl amidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, acrylic acid or methacrylic acid ester, disulfide and ketone Prevent and improve reactive wrinkles with functional groups that covalently bind one or more proteins It may include minutes.
For example, as in Scheme 1, the carbodiimide-based compound produced by the first reaction may include a wrinkle preventing and improving component combined with a carbodiimide group. In addition, the present invention may include a cosmetic composition for preventing and improving wrinkles comprising the reactive wrinkle prevention and improvement component.
In the cosmetic composition for preventing and improving wrinkles according to the present invention, fatty acids such as palmitic acid and stearic acid, fatty alcohols, long-chain alkyl quaternary ammonium salts such as straight and branched chains, etc. Formulation may be facilitated when used in combination with a cationic polymer such as cationic surfactant, cationic cellulose, cationic guar, and cationic polyvinylpyrrolidone, and silicone. In addition, to formulate into cosmetic formulations for the formulation of cosmetics such as solvents, surfactants, thickeners, stabilizers, preservatives, colorants, pH adjusters, metal ion sequestrants, colorants, pearlescent agents, cosmetics, pigments, powder particles, etc. Components may be incidentally included. The component for the formulation may be used 40 to 99 parts by weight based on 100 parts by weight of the total composition.
The cosmetic composition for preventing and improving wrinkles according to the present invention may be used in the formulation of a cosmetic composition for preventing and improving wrinkles, including a component for preventing and improving wrinkles having a functional group. Examples of application of skin products generally include skin care, basic cosmetics (cosmetics, serums, essences, lotions, creams), color cosmetics (makeup base, foundation, powder, eye shadow, lip gloss, lipstick, lip balm, etc.) , Makeup for nails (nail polish, nutrients, reinforcing agents, top coats, etc.), cleaning cosmetics (foam cleansing, cleansing oil, cleansing lotion, cleansing cream, cleansing gel, pack, mask, soap, cleansing tissue, etc.), sun care Cosmetics, body cosmetics (body lotion, shower gel, body cream, body oil, etc.) may include all.
More preferably, the cosmetic composition for preventing and improving wrinkles comprises a carbodiimide-based compound and at the same time includes a component for preventing and improving wrinkles having a reactive functional group, and when the above agent is deteriorated in water, It is easier to maintain its activity in non-aqueous formulations, and the reaction may occur by mixing with a buffer for pH control immediately prior to use, or by contacting with water during the cleaning process. Examples of non-aqueous formulations include liquid form, sheet form, powder powder form, tablet form, oil, wax, ampoule, gel and the like used as conventional non-aqueous cosmetic preparations. In addition, the carbodiimide-based compound and the wrinkle prevention and amelioration component may be formulated as a single agent in encapsulated form or as two agents in separate forms, respectively. In addition, a method of blocking a derivative of a form in which a reactive functional group and a component having a function of preventing and improving wrinkles through encapsulation from water can be used.
2-basic acid ester oils and polyols, such as dioctyl succinate, dioctyl adipate, diethyl sebacate, etc., in order to increase the effect of preventing and improving wrinkles having functional groups in the cosmetic composition for preventing and improving wrinkles according to the present invention; Polyethylene glycol, propylene glycol, hexylene glycol, butanediol and their isomers, glycerol, benzyl alcohol, ethoxydiglycol and derivatives thereof can be used. The above-mentioned solvents increase the permeability of the skin and are used as solvents of poorly soluble substances. More preferably, solvents used to increase the activity retention effect of the anti-wrinkle and improvement component having a functional group include diethyl sebacate, ethoxyglycol, bis-ethoxyglycol cyclohexane 1,4-dicarboxylate, and the like. .
Hereinafter, the present invention will be described in detail by the following examples. However, the following examples are illustrative of the present invention, and the present invention is not limited to the following examples.
Example 1 and 2 and Comparative Example One
The anti-wrinkle compositions of Examples 1, 2 and Comparative Example 1 were prepared with the compositions and contents shown in Table 1 below, and each of the prepared compositions was applied to the neck wrinkles of 10 subjects and left at room temperature for 30 minutes. Induce reaction and wash off with primary running water and soap twice daily for 10 days, and then again after 10 days, the 5-point scale (5 very good, 4 slightly good, 3 no difference, 2 no effect, 1 very no effect) to compare the anti-wrinkle effect.
Experimental results of Examples 1 to 2 and Comparative Example 1 (Table 2), Examples 1 to 2 containing carbodiimide compared to Comparative Example 1 containing no carbodiimide but including retinyl acetate The effect of covalent bond formation showed a better wrinkle improvement effect. In particular, Example 2 using the polymer carbodiimide showed a better wrinkle improvement effect.
(n = 20, 5-point scale)
Formulation example : Wrinkle improvement Cosmetic Produce
According to the conventional cosmetic preparation method, to prepare a cosmetic for improving wrinkles in the components and contents of the following Table 3.
Claims (9)
(2)
In the above formula (2), n is 1 to 100 and m is 1 to 100.
The wrinkle prevention and improvement component is a cosmetic composition for preventing and improving wrinkles comprising a carboxyl group or an amine group in the molecule.
The anti-wrinkle and improvement ingredients include vitamin A (retinoid), vitamin E (tocopherol), flavonoids, polyphenols, SOD (Superoxide dismutase), coenzyme Q10, alpha-lipoic acid, acetylhexapeptide, retinol, retinyl palmitate, retinol Group consisting of Neil Acetate, Adenosine, Vitamin C, Collagen, Hexapeptide3, Skin Cell Growth Factor (EGF), Kinetine, Snail Mucus, Aquanomid, Ceramide, Glycerin, Hyaluronic Acid, Betaine, Chitosan and Urea Cosmetic composition for preventing and improving wrinkles is one or more selected from.
The functional group covalently bonded with the protein is imidoester, arylazide, diazirine, hydroxymethyl phosphine, pentafluorophenylester, pyridyl disulfide, sulfo-hydroxysuccinimide ester, alkoxy amine, hydrazide, Haloacetyl, azide, carbonate, aldehyde, propionaldehyde, butylaldehyde, nitrophenyl carbonate, aziridine, isocyanate, thiocyanate, epoxide, tresylate, succinimide, hydroxysuccinimidyl ester, imidazole, Cosmetics for preventing and improving wrinkles, which are at least one selected from the group consisting of oxycarbonyl amidazole, imine, thiol, maleimide, vinylsulfone, ethyleneimine, thioether, acrylonitrile, acrylic acid or methacrylic acid ester, disulfide and ketone Composition.
Wrinkle prevention and improvement cosmetic composition comprising a carbodiimide compound in an amount of 0.001 to 10% by weight in 100% by weight of the total composition.
The carbodiimide-based compound and the wrinkle preventing and improving component are formulated in a single agent in encapsulated form; A cosmetic composition for preventing and improving wrinkles, wherein the carbodiimide-based compound and the wrinkle preventing and improving component are formulated in two separate forms.
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| KR1020130152354A KR102006952B1 (en) | 2013-12-09 | 2013-12-09 | Cosmetics compositions for prevention and improvement of wrinkle |
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| KR1020130152354A KR102006952B1 (en) | 2013-12-09 | 2013-12-09 | Cosmetics compositions for prevention and improvement of wrinkle |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP6873103B2 (en) * | 2015-08-27 | 2021-05-19 | エルジー ハウスホールド アンド ヘルスケア リミテッド | Composition for surface modification |
| KR102491996B1 (en) * | 2015-12-22 | 2023-01-26 | 주식회사 엘지생활건강 | Cosmetics compositions for prevention and improvement of wrinkle |
| KR102491997B1 (en) * | 2015-12-22 | 2023-01-26 | 주식회사 엘지생활건강 | Cosmetics compositions for prevention and improvement of wrinkle |
| KR102502511B1 (en) * | 2015-12-22 | 2023-02-22 | 주식회사 엘지생활건강 | Cosmetics compositions for prevention and improvement of wrinkle |
| KR102094061B1 (en) | 2017-09-18 | 2020-03-26 | 진명종 | Method of anti-wrinkle and Anti-aging cosmetics compositions using colloidal gold |
| KR102374634B1 (en) * | 2020-01-30 | 2022-03-16 | 김영미 | Anti-aging composition comprising alpha lipoic acid and antioxidant applied with skin-like or permeable phospholipid technology |
| KR20230096601A (en) | 2021-12-23 | 2023-06-30 | 주식회사 앤나코스메틱 | Serum cosmetics composition effective for anti-wrinkle and hypopigmentation containing gold grain |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002013773A2 (en) * | 2000-08-16 | 2002-02-21 | Unilever Plc | Cosmetic composition |
| KR100770117B1 (en) * | 2006-11-03 | 2007-10-24 | 주식회사 엘지생활건강 | Skin care composition for external use having anti-wrinkle properties |
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| KR101351467B1 (en) | 2007-01-05 | 2014-01-16 | 주식회사 엘지생활건강 | Mixed-type Personal Care Product for Skin or Hair |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002013773A2 (en) * | 2000-08-16 | 2002-02-21 | Unilever Plc | Cosmetic composition |
| KR100770117B1 (en) * | 2006-11-03 | 2007-10-24 | 주식회사 엘지생활건강 | Skin care composition for external use having anti-wrinkle properties |
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