KR102004563B1 - 피부 질환 및 그 상태를 치료하기 위한 7-(1h-이미다졸-4-일메틸)-5,6,7,8-테트라히드로-퀴놀린 을 포함하는 약제학적 조성물 - Google Patents

피부 질환 및 그 상태를 치료하기 위한 7-(1h-이미다졸-4-일메틸)-5,6,7,8-테트라히드로-퀴놀린 을 포함하는 약제학적 조성물 Download PDF

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KR102004563B1
KR102004563B1 KR1020147015533A KR20147015533A KR102004563B1 KR 102004563 B1 KR102004563 B1 KR 102004563B1 KR 1020147015533 A KR1020147015533 A KR 1020147015533A KR 20147015533 A KR20147015533 A KR 20147015533A KR 102004563 B1 KR102004563 B1 KR 102004563B1
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Prior art keywords
skin
pharmaceutical composition
imidazol
ylmethyl
tetrahydro
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Expired - Fee Related
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Korean (ko)
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KR20140107237A (ko
Inventor
모하메드 아이. 디바스
에드워드 씨. 히시아
존 이. 도넬로
다니엘 더블유. 길
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알러간, 인코포레이티드
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
KR1020147015533A 2011-11-10 2012-11-08 피부 질환 및 그 상태를 치료하기 위한 7-(1h-이미다졸-4-일메틸)-5,6,7,8-테트라히드로-퀴놀린 을 포함하는 약제학적 조성물 Expired - Fee Related KR102004563B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161558104P 2011-11-10 2011-11-10
US61/558,104 2011-11-10
PCT/US2012/064075 WO2013070861A1 (en) 2011-11-10 2012-11-08 Pharmaceutical compositions comprising 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions

Publications (2)

Publication Number Publication Date
KR20140107237A KR20140107237A (ko) 2014-09-04
KR102004563B1 true KR102004563B1 (ko) 2019-07-26

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ID=47178364

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KR1020147015533A Expired - Fee Related KR102004563B1 (ko) 2011-11-10 2012-11-08 피부 질환 및 그 상태를 치료하기 위한 7-(1h-이미다졸-4-일메틸)-5,6,7,8-테트라히드로-퀴놀린 을 포함하는 약제학적 조성물

Country Status (22)

Country Link
US (4) US20130123303A1 (https=)
EP (3) EP2776034B1 (https=)
JP (2) JP6359456B2 (https=)
KR (1) KR102004563B1 (https=)
CN (1) CN104136029A (https=)
AR (1) AR088845A1 (https=)
AU (2) AU2012335803B2 (https=)
BR (1) BR112014011336A2 (https=)
CA (1) CA2855005C (https=)
CL (1) CL2014001242A1 (https=)
DK (1) DK2776034T3 (https=)
ES (1) ES2635421T3 (https=)
IL (3) IL232483B (https=)
MX (1) MX350662B (https=)
MY (1) MY182553A (https=)
PH (1) PH12014501051A1 (https=)
RU (2) RU2630978C2 (https=)
SG (3) SG11201402246RA (https=)
TW (3) TWI708604B (https=)
UA (1) UA109359C2 (https=)
WO (1) WO2013070861A1 (https=)
ZA (1) ZA201403396B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283217B2 (en) 2011-11-10 2016-03-15 Allergan, Inc. Pharmaceutical compositions comprising 7-(1 H-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions
BR112015027984A2 (pt) * 2013-05-06 2017-09-05 Allergan Inc Agonistas alfa adrenérgicos para o tratamento de lesão de tecido
FR3061434B1 (fr) * 2017-01-04 2019-07-12 Pierre Fabre Dermo-Cosmetique Composition cosmetique comprenant une association d'huile de pongamia et de pentylene glycol 4-t-butylcyclohexanol pour lutter contre la rosacee
RU2727695C1 (ru) * 2020-02-13 2020-07-22 Мурад Умарович Магомедов Способ комплексного лечения ринофимы

Citations (2)

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US20040242588A1 (en) 2003-05-27 2004-12-02 Jack Dejovin Compounds, formulations, and methods for treating or preventing rosacea
US20070179182A1 (en) * 2006-02-02 2007-08-02 Ken Chow 7-((1H-imidazol-4-yl)methyl)-5,6,7,8-tetrahydroquinoline

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DE69940227D1 (de) * 1998-05-08 2009-02-12 Univ Miami Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea
US6242442B1 (en) * 1998-12-17 2001-06-05 Alcon Laboratories, Inc. Brinzolamide and brimonidine for treating ocular conditions
US20010049369A1 (en) * 2000-02-10 2001-12-06 Jablonski Monica M. Brimonidine compositions and methods for retinal degeneration
US6468989B1 (en) 2000-07-13 2002-10-22 Dow Pharmaceutical Sciences Gel compositions containing metronidazole
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US20020198209A1 (en) 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US6680062B2 (en) 2001-10-05 2004-01-20 Color Access, Inc. Anti-irritating rosacea treatment
US7030149B2 (en) * 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US20040146539A1 (en) * 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
US20050020600A1 (en) * 2003-07-23 2005-01-27 Scherer Warren J. Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists
KR20060109947A (ko) * 2003-11-20 2006-10-23 오쎄라 파마슈티걸즈, 인크. 황반 변성 및 다른 안과 질환의 개선
US7812049B2 (en) 2004-01-22 2010-10-12 Vicept Therapeutics, Inc. Method and therapeutic/cosmetic topical compositions for the treatment of rosacea and skin erythema using α1-adrenoceptor agonists
JP4955543B2 (ja) * 2004-05-25 2012-06-20 サンズローザ ファーマシューティカル ディヴェロップメント インコーポレイテッド 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法
US20070203144A1 (en) * 2006-01-17 2007-08-30 Allergan, Inc. Use of Memantine and Brimonidine to Attenuate Vitreoretinal Vascular Endothelial Growth Factor (VEGF) Protein Levels in Animals
RU2321399C1 (ru) * 2006-06-01 2008-04-10 Федеральное государственное учреждение "Нижегородский научно-исследовательский кожно-венерологический институт Федерального агентства по здравоохранению и социальному развитию" Способ лечения больных розацеа
US20090005450A1 (en) * 2007-04-09 2009-01-01 Belinda Tsao Nivaggioli Use of creatine compounds for the treatment of eye disorders
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WO2009052073A2 (en) * 2007-10-18 2009-04-23 Allergan, Inc. Method of treating sensorimotor disorders with alpha-2 adrenergic receptor agonists
US20100203165A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US20100028266A1 (en) * 2008-08-01 2010-02-04 Alpha Synergy Development. Inc. Composition and methods for treating allergic response
FR2942138A1 (fr) 2009-02-16 2010-08-20 Galderma Res & Dev Association de composes pour le traitement ou la prevention des affections dermatologiques
CA2779063A1 (en) * 2009-10-26 2011-05-05 Galderma Pharma S.A. Methods of treating or preventing acute erythema
US8394800B2 (en) * 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
US8513247B2 (en) * 2010-03-26 2013-08-20 Galderma Laboratories, L.P. Methods and compositions for safe and effective treatment of erythema
MX2012010823A (es) * 2010-03-26 2012-10-10 Galderma Res & Dev Metodos y composiciones mejoradas para tratamiento seguro y efectivo de telangiectasia.
WO2012017077A1 (en) * 2010-08-06 2012-02-09 Galderma Research & Development Combination of compounds for treating or preventing skin diseases

Patent Citations (2)

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US20040242588A1 (en) 2003-05-27 2004-12-02 Jack Dejovin Compounds, formulations, and methods for treating or preventing rosacea
US20070179182A1 (en) * 2006-02-02 2007-08-02 Ken Chow 7-((1H-imidazol-4-yl)methyl)-5,6,7,8-tetrahydroquinoline

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Publication number Publication date
AU2012335803A1 (en) 2014-05-29
EP3184110A1 (en) 2017-06-28
US9308201B2 (en) 2016-04-12
DK2776034T3 (en) 2017-07-10
US20160051534A1 (en) 2016-02-25
SG11201402246RA (en) 2014-06-27
UA109359C2 (xx) 2015-08-10
CN104136029A (zh) 2014-11-05
JP6359456B2 (ja) 2018-07-18
IL261269A (en) 2018-10-31
SG10201609145PA (en) 2016-12-29
WO2013070861A1 (en) 2013-05-16
JP2017149767A (ja) 2017-08-31
CL2014001242A1 (es) 2014-11-14
ZA201403396B (en) 2015-07-29
CA2855005A1 (en) 2013-05-16
AR088845A1 (es) 2014-07-10
TWI580424B (zh) 2017-05-01
RU2667645C1 (ru) 2018-09-21
SG10201809506TA (en) 2018-11-29
IL232483B (en) 2018-10-31
ES2635421T3 (es) 2017-10-03
RU2630978C2 (ru) 2017-09-15
EP2776034A1 (en) 2014-09-17
MX2014005640A (es) 2014-09-22
TW201328694A (zh) 2013-07-16
AU2016216627B2 (en) 2017-10-19
IL268757A (en) 2019-10-31
AU2012335803B2 (en) 2016-05-26
EP2776034B1 (en) 2017-03-22
US20170095466A1 (en) 2017-04-06
EP3763370A1 (en) 2021-01-13
NZ624771A (en) 2016-11-25
BR112014011336A2 (pt) 2017-05-02
JP2014533271A (ja) 2014-12-11
AU2016216627A1 (en) 2016-09-08
MY182553A (en) 2021-01-25
RU2014122758A (ru) 2015-12-20
US20130123303A1 (en) 2013-05-16
TWI708604B (zh) 2020-11-01
IL232483A0 (en) 2014-06-30
EP3184110B1 (en) 2020-10-07
TW201713338A (zh) 2017-04-16
US20150231128A1 (en) 2015-08-20
MX350662B (es) 2017-09-13
PH12014501051A1 (en) 2022-11-02
CA2855005C (en) 2016-11-22
KR20140107237A (ko) 2014-09-04
JP6526737B2 (ja) 2019-06-05
TW202014189A (zh) 2020-04-16

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