KR101992345B9 - 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도 - Google Patents

프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도

Info

Publication number
KR101992345B9
KR101992345B9 KR1020170184819A KR20170184819A KR101992345B9 KR 101992345 B9 KR101992345 B9 KR 101992345B9 KR 1020170184819 A KR1020170184819 A KR 1020170184819A KR 20170184819 A KR20170184819 A KR 20170184819A KR 101992345 B9 KR101992345 B9 KR 101992345B9
Authority
KR
South Korea
Prior art keywords
promoter polynucleotide
signal polypeptide
polynucleotide signal
polypeptide
promoter
Prior art date
Application number
KR1020170184819A
Other languages
English (en)
Other versions
KR101992345B1 (ko
Inventor
김용인
송지윤
윤지애
조승기
노현진
Original Assignee
(주)메디톡스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1020170184819A priority Critical patent/KR101992345B1/ko
Application filed by (주)메디톡스 filed Critical (주)메디톡스
Priority to CN201880084821.4A priority patent/CN111601895B/zh
Priority to EP18897474.5A priority patent/EP3732292A4/en
Priority to PCT/KR2018/013520 priority patent/WO2019132231A1/en
Priority to US16/959,058 priority patent/US11661445B2/en
Priority to JP2020535620A priority patent/JP7189218B2/ja
Application granted granted Critical
Publication of KR101992345B1 publication Critical patent/KR101992345B1/ko
Priority to JP2022137521A priority patent/JP2022180395A/ja
Priority to JP2022137522A priority patent/JP2022180396A/ja
Priority to US18/301,015 priority patent/US20230295249A1/en
Publication of KR101992345B9 publication Critical patent/KR101992345B9/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
KR1020170184819A 2017-12-29 2017-12-29 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도 KR101992345B1 (ko)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020170184819A KR101992345B1 (ko) 2017-12-29 2017-12-29 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도
EP18897474.5A EP3732292A4 (en) 2017-12-29 2018-11-08 PROMOTING POLYPEPTIDE, SIGNAL POLYPEPTIDE AND ASSOCIATED USES
PCT/KR2018/013520 WO2019132231A1 (en) 2017-12-29 2018-11-08 Promoter polynucleotide, signal polypeptide, and use thereof
US16/959,058 US11661445B2 (en) 2017-12-29 2018-11-08 Promoter polynucleotide, signal polypeptide and use thereof
CN201880084821.4A CN111601895B (zh) 2017-12-29 2018-11-08 启动子多核苷酸、信号多肽以及其用途
JP2020535620A JP7189218B2 (ja) 2017-12-29 2018-11-08 プロモーターポリヌクレオチド、シグナルポリペプチド、及びその用途
JP2022137521A JP2022180395A (ja) 2017-12-29 2022-08-31 プロモーターポリヌクレオチド、シグナルポリペプチド、及びその用途
JP2022137522A JP2022180396A (ja) 2017-12-29 2022-08-31 プロモーターポリヌクレオチド、シグナルポリペプチド、及びその用途
US18/301,015 US20230295249A1 (en) 2017-12-29 2023-04-14 Promoter polynucleotide, signal polypeptide and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170184819A KR101992345B1 (ko) 2017-12-29 2017-12-29 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도

Publications (2)

Publication Number Publication Date
KR101992345B1 KR101992345B1 (ko) 2019-09-27
KR101992345B9 true KR101992345B9 (ko) 2023-09-07

Family

ID=67067710

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020170184819A KR101992345B1 (ko) 2017-12-29 2017-12-29 프로모터 폴리뉴클레오티드, 신호 폴리펩티드 및 그의 용도

Country Status (6)

Country Link
US (2) US11661445B2 (ko)
EP (1) EP3732292A4 (ko)
JP (3) JP7189218B2 (ko)
KR (1) KR101992345B1 (ko)
CN (1) CN111601895B (ko)
WO (1) WO2019132231A1 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102238519B1 (ko) * 2018-12-28 2021-04-13 (주)메디톡스 외래 단백질을 발현하는 미생물, 및 그의 용도
CN110643571B (zh) * 2019-10-22 2021-07-27 康妍葆(北京)干细胞科技有限公司 人角蛋白6a在干细胞培养中的应用及产品
KR20210129516A (ko) * 2020-04-20 2021-10-28 주식회사 리비옴 혈관 작동성 장 펩티드를 발현하는 미생물, 및 그의 용도
WO2022065643A1 (ko) * 2020-09-28 2022-03-31 한국화학연구원 분비 신호서열에 융합된 표적산물 결합 단백질을 코딩하는 폴리뉴클레오티드를 포함하는 재조합 미생물, 그를 포함하는 조성물 및 그를 이용하여 표적산물을 생산하는 방법
EP4370673A1 (en) * 2021-07-12 2024-05-22 Xylogenics, Inc. Strains of saccharomyces cerevisiae that exhibit an increased ability to ferment oligosaccharides into ethanol without supplemental glucoamylase and methods of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4025700A (en) * 1999-03-22 2000-10-09 Novo Nordisk Biotech, Inc. Promoters for expressing genes in a fungal cell
WO2008084115A2 (en) 2007-01-12 2008-07-17 Actogenix N.V. Lactococcus promoters and uses thereof
ES2568938T3 (es) * 2009-04-28 2016-05-05 Vanderbilt University Composiciones y procedimientos de tratamiento de trastornos que implican apoptosis de células epiteliales
MX2012002095A (es) * 2009-08-21 2012-04-10 Novozymes As Polipeptidos que tienen actividad de isoamilasa y polinucleotidos que codifican los mismos.
WO2011039137A1 (en) 2009-09-29 2011-04-07 Actogenix N.V. Lactobacillus and streptococcus promoters and uses thereof

Also Published As

Publication number Publication date
CN111601895A (zh) 2020-08-28
EP3732292A4 (en) 2021-09-22
US11661445B2 (en) 2023-05-30
JP7189218B2 (ja) 2022-12-13
JP2022180395A (ja) 2022-12-06
JP2022180396A (ja) 2022-12-06
JP2021508464A (ja) 2021-03-11
KR101992345B1 (ko) 2019-09-27
CN111601895B (zh) 2024-05-10
WO2019132231A1 (en) 2019-07-04
US20230295249A1 (en) 2023-09-21
US20200339637A1 (en) 2020-10-29
EP3732292A1 (en) 2020-11-04

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Legal Events

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G170 Re-publication after modification of scope of protection [patent]
G170 Re-publication after modification of scope of protection [patent]