KR101964406B1 - 피질 도파민 작용- 및 ｎｍｄａ-수용체-매개 글루타메이트 작용 신경전달의 신규 조절제 - Google Patents
피질 도파민 작용- 및 ｎｍｄａ-수용체-매개 글루타메이트 작용 신경전달의 신규 조절제 Download PDFInfo
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- KR101964406B1 KR101964406B1 KR1020137030198A KR20137030198A KR101964406B1 KR 101964406 B1 KR101964406 B1 KR 101964406B1 KR 1020137030198 A KR1020137030198 A KR 1020137030198A KR 20137030198 A KR20137030198 A KR 20137030198A KR 101964406 B1 KR101964406 B1 KR 101964406B1
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- phenoxy
- ethyl
- methylsulfonyl
- fluoro
- amine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
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| US201161476810P | 2011-04-19 | 2011-04-19 | |
| US61/476,810 | 2011-04-19 | ||
| DKPA201170187 | 2011-04-19 | ||
| DKPA201170187 | 2011-04-19 | ||
| DKPA201170495 | 2011-09-06 | ||
| DKPA201170495 | 2011-09-06 | ||
| PCT/EP2012/056959 WO2012143337A1 (en) | 2011-04-19 | 2012-04-17 | Novel modulators of cortical dopaminergic- and nmda-receptor-mediated glutamatergic neurotransmission |
Publications (2)
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| KR20140024901A KR20140024901A (ko) | 2014-03-03 |
| KR101964406B1 true KR101964406B1 (ko) | 2019-04-01 |
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| JP6789681B2 (ja) * | 2016-06-10 | 2020-11-25 | スリーエム イノベイティブ プロパティズ カンパニー | グラフィックフィルム、ライセンスプレート、及びグラフィックフィルムの製造方法 |
| BR112021023563A2 (pt) * | 2019-05-24 | 2022-01-04 | Integrative Res Laboratories Sweden Ab | Sais farmaceuticamente aceitáveis de [2-(3-fluoro-5-metano-sulfonilfenóxi)etil](propil) amina e usos dos mesmos |
| EP4125840A1 (en) | 2020-03-27 | 2023-02-08 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of synucleinopathies |
| EP4243801A1 (en) | 2020-11-10 | 2023-09-20 | Integrative Research Laboratories Sweden AB | [2-(3-fluoro-5-methanesulfonylphenoxy)ethyl](propyl)amine (mesdopetam) for use in the prevention or reduction of sensitization to a pharmaceutical drug for parkinson's disease, in particular l-dopa induced dyskinesias |
| WO2024042540A1 (en) * | 2022-08-24 | 2024-02-29 | Alkem Laboratories Limited | Mesdopetam compositions |
| WO2024062344A1 (en) | 2022-09-21 | 2024-03-28 | Assia Chemical Industries Ltd. | Solid state forms of mesdopetam and salts therof |
| GB202312055D0 (en) | 2023-08-07 | 2023-09-20 | Ipsen Biopharm Ltd | Pharmaceutical compositions |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2006067462A1 (en) | 2004-12-23 | 2006-06-29 | Glaxo Group Limited | 1,6 - substituted (3r,6r) -3- (2,3-dihydro-1h-inden-2-yl)-2,5-piperazinedione derivatives as oxytocin receptor antagonists for the treatment of pre-term labour, dysmenorrhea and endometriosis |
| WO2007063789A1 (ja) | 2005-11-29 | 2007-06-07 | Kissei Pharmaceutical Co., Ltd. | 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途 |
Family Cites Families (11)
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| JPS51123821A (en) | 1975-04-18 | 1976-10-28 | Nippon Kayaku Co Ltd | An algicide and protective agent |
| IL87181A (en) * | 1987-08-07 | 1993-08-18 | Sanofi Sa | Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them |
| GB8823405D0 (en) * | 1988-10-05 | 1988-11-09 | Erba Carlo Spa | Aryloxy-arythio-heteraryloxy-heteroarylthio-alkenylene derivatives of amines |
| PT707007E (pt) | 1994-10-14 | 2002-06-28 | Merck Patent Gmbh | Derivados amino(tio)eter como agentes activos no snc |
| DOP2001000189A (es) * | 2000-06-30 | 2002-03-30 | Pfizer Prod Inc | Benzofenonas y sulfonas como inhibidores de la captación de glicina |
| JP2006193494A (ja) | 2005-01-17 | 2006-07-27 | Dainippon Ink & Chem Inc | ４級アンモニウム系化合物を有効成分とする心臓疾患治療剤 |
| WO2007072041A1 (en) | 2005-12-23 | 2007-06-28 | Astex Therapeutics Limited | Therapeutic compounds |
| AU2007218086A1 (en) * | 2006-02-15 | 2007-08-30 | M's Science Corporation | Piperazine derivatives |
| NZ588209A (en) | 2008-04-29 | 2012-08-31 | Nsab Af Neurosearch Sweden Ab | 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives for the modulation of dopaminergic function in the central nervous system |
| US20110105462A1 (en) | 2008-04-29 | 2011-05-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| DK2271638T3 (da) | 2008-04-29 | 2011-11-28 | Nsab Af Neurosearch Sweden Ab | Modulatorer af dopaminneurotransmission |
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2012
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006067462A1 (en) | 2004-12-23 | 2006-06-29 | Glaxo Group Limited | 1,6 - substituted (3r,6r) -3- (2,3-dihydro-1h-inden-2-yl)-2,5-piperazinedione derivatives as oxytocin receptor antagonists for the treatment of pre-term labour, dysmenorrhea and endometriosis |
| WO2007063789A1 (ja) | 2005-11-29 | 2007-06-07 | Kissei Pharmaceutical Co., Ltd. | 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途 |
Also Published As
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| ES2566634T3 (es) | 2016-04-14 |
| CA2832874C (en) | 2019-06-11 |
| JP5876140B2 (ja) | 2016-03-02 |
| HK1192877A1 (zh) | 2014-09-05 |
| WO2012143337A1 (en) | 2012-10-26 |
| US20140128360A1 (en) | 2014-05-08 |
| EP2699543B1 (en) | 2016-03-02 |
| US9120728B2 (en) | 2015-09-01 |
| IL228705A (en) | 2016-11-30 |
| RU2013147917A (ru) | 2015-05-27 |
| KR20140024901A (ko) | 2014-03-03 |
| AU2012244867C1 (en) | 2017-01-19 |
| EP2699543A1 (en) | 2014-02-26 |
| IL228705A0 (en) | 2013-12-31 |
| ZA201307227B (en) | 2014-12-23 |
| MX2013012025A (es) | 2014-06-23 |
| AU2012244867B2 (en) | 2016-07-28 |
| CA2832874A1 (en) | 2012-10-26 |
| DK2699543T3 (en) | 2016-03-29 |
| CN103476746A (zh) | 2013-12-25 |
| AU2012244867A1 (en) | 2013-10-17 |
| US9006227B2 (en) | 2015-04-14 |
| SG193992A1 (en) | 2013-11-29 |
| RU2593500C2 (ru) | 2016-08-10 |
| US20150148426A1 (en) | 2015-05-28 |
| CN103476746B (zh) | 2015-10-14 |
| JP2014518552A (ja) | 2014-07-31 |
| PL2699543T3 (pl) | 2016-10-31 |
| MX341847B (es) | 2016-09-05 |
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