KR101911362B1 - 타펜타돌을 함유하는 반고체 수성 약제학적 조성물 - Google Patents

타펜타돌을 함유하는 반고체 수성 약제학적 조성물 Download PDF

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Publication number
KR101911362B1
KR101911362B1 KR1020137026185A KR20137026185A KR101911362B1 KR 101911362 B1 KR101911362 B1 KR 101911362B1 KR 1020137026185 A KR1020137026185 A KR 1020137026185A KR 20137026185 A KR20137026185 A KR 20137026185A KR 101911362 B1 KR101911362 B1 KR 101911362B1
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pharmaceutical composition
weight
semi
composition according
composition
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KR20140013020A (ko
Inventor
울리히 라인홀트
마르크 쉴러
에바 불슈텐
사비너 카리너 카트린 잉겔브레흐트
로저르 카롤뤼스 아우귀스타 엠브러흐츠
울리히 파일
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그뤼넨탈 게엠베하
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020137026185A 2011-03-04 2012-03-02 타펜타돌을 함유하는 반고체 수성 약제학적 조성물 Expired - Fee Related KR101911362B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161449329P 2011-03-04 2011-03-04
US61/449,329 2011-03-04
EP11003603 2011-05-03
EP11003603.5 2011-05-03
PCT/EP2012/000906 WO2012119729A1 (en) 2011-03-04 2012-03-02 Semisolid aqueous pharmaceutical composition containing tapentadol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020187029861A Division KR102039320B1 (ko) 2011-03-04 2012-03-02 타펜타돌을 함유하는 반고체 수성 약제학적 조성물

Publications (2)

Publication Number Publication Date
KR20140013020A KR20140013020A (ko) 2014-02-04
KR101911362B1 true KR101911362B1 (ko) 2018-10-25

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ID=44652117

Family Applications (2)

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KR1020137026185A Expired - Fee Related KR101911362B1 (ko) 2011-03-04 2012-03-02 타펜타돌을 함유하는 반고체 수성 약제학적 조성물
KR1020187029861A Expired - Fee Related KR102039320B1 (ko) 2011-03-04 2012-03-02 타펜타돌을 함유하는 반고체 수성 약제학적 조성물

Family Applications After (1)

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Country Status (24)

Country Link
US (3) US9446008B2 (https=)
EP (3) EP3290029B1 (https=)
JP (3) JP6027549B2 (https=)
KR (2) KR101911362B1 (https=)
CN (1) CN103501774A (https=)
AU (2) AU2012224954C1 (https=)
BR (1) BR112013022556A8 (https=)
CA (1) CA2828637C (https=)
CY (1) CY1119725T1 (https=)
DK (1) DK2680834T3 (https=)
EA (2) EA033171B1 (https=)
ES (2) ES2910085T3 (https=)
HR (1) HRP20171836T1 (https=)
HU (1) HUE037491T2 (https=)
IL (2) IL227826B (https=)
LT (1) LT2680834T (https=)
MX (2) MX344473B (https=)
NO (1) NO2680834T3 (https=)
PL (1) PL2680834T3 (https=)
PT (2) PT3766489T (https=)
RS (1) RS56692B1 (https=)
SI (1) SI2680834T1 (https=)
WO (1) WO2012119729A1 (https=)
ZA (1) ZA201306480B (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
KR20180116463A (ko) * 2011-03-04 2018-10-24 그뤼넨탈 게엠베하 타펜타돌을 함유하는 반고체 수성 약제학적 조성물

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MX388963B (es) 2011-03-04 2025-03-20 Gruenenthal Gmbh Formulacion farmaceutica acuosa de tapentadol para administracion oral
US9395306B2 (en) 2011-08-05 2016-07-19 Halliburton Energy Services, Inc. Methods for monitoring fluids within or produced from a subterranean formation during acidizing operations using opticoanalytical devices
US8997860B2 (en) 2011-08-05 2015-04-07 Halliburton Energy Services, Inc. Methods for monitoring the formation and transport of a fracturing fluid using opticoanalytical devices
US8619256B1 (en) 2012-09-14 2013-12-31 Halliburton Energy Services, Inc. Systems and methods for monitoring the properties of a fluid cement composition in a flow path
US20140076550A1 (en) 2012-09-14 2014-03-20 Halliburton Energy Services, Inc. Systems and Methods for Detecting Microannulus Formation and Remediation
US9228940B2 (en) 2012-09-14 2016-01-05 Halliburton Energy Services, Inc. Systems, methods, and apparatuses for in situ monitoring of cement fluid compositions and setting processes thereof
EP3027214A1 (en) * 2013-08-02 2016-06-08 ratiopharm GmbH Composition comprising tapentadol in a dissolved form
EP2845625A1 (en) 2013-09-04 2015-03-11 Grünenthal GmbH Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome
PE20171651A1 (es) 2015-03-27 2017-11-13 Gruenenthal Chemie Formulacion estable para administracion parenteral de tapentadol
EP3515412B1 (en) 2016-09-23 2025-04-23 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
JP2021532112A (ja) * 2018-07-24 2021-11-25 ドクトア・アウグスト・ボルフ・ゲーエムベーハー・ウント・コンパニー・カー・ゲー−アルツナイミツテル 抗コリン性化合物の局所用エマルション
BR112021004199A2 (pt) 2018-09-07 2021-05-25 R.P. Scherer Technologies, Llc estabilização de formas de dosagem à base de lipídio sólido ou semissólido através da cura e da adição de tensoativo(s) de baixo teor de hlb
JP7646560B2 (ja) 2019-03-18 2025-03-17 サンスター アメリカス インク オーラルケア組成物

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180116463A (ko) * 2011-03-04 2018-10-24 그뤼넨탈 게엠베하 타펜타돌을 함유하는 반고체 수성 약제학적 조성물
KR102039320B1 (ko) * 2011-03-04 2019-11-01 그뤼넨탈 게엠베하 타펜타돌을 함유하는 반고체 수성 약제학적 조성물

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DK2680834T3 (en) 2017-12-04
AU2017200040A1 (en) 2017-02-02
EP3290029A1 (en) 2018-03-07
AU2012224954C1 (en) 2017-04-06
EA033171B1 (ru) 2019-09-30
MX2013010100A (es) 2013-10-01
US20160346229A1 (en) 2016-12-01
MX344473B (es) 2016-12-16
HRP20171836T1 (hr) 2017-12-29
JP6027549B2 (ja) 2016-11-16
AU2017200040B2 (en) 2018-09-06
BR112013022556A2 (pt) 2016-12-06
CA2828637C (en) 2019-06-11
KR20180116463A (ko) 2018-10-24
BR112013022556A8 (pt) 2018-01-16
IL227826A0 (en) 2013-09-30
CY1119725T1 (el) 2018-06-27
US9446008B2 (en) 2016-09-20
HUE037491T2 (hu) 2018-09-28
KR20140013020A (ko) 2014-02-04
WO2012119729A1 (en) 2012-09-13
JP6670283B2 (ja) 2020-03-18
AU2012224954A1 (en) 2013-09-19
AU2012224954B2 (en) 2016-10-20
ES2910085T3 (es) 2022-05-11
JP2014506900A (ja) 2014-03-20
ES2654407T3 (es) 2018-02-13
EP2680834B1 (en) 2017-10-18
PT3766489T (pt) 2022-04-07
ZA201306480B (en) 2014-05-28
EA201600442A1 (ru) 2017-02-28
EP3290029B1 (en) 2020-09-02
NO2680834T3 (https=) 2018-03-17
IL227826B (en) 2018-04-30
KR102039320B1 (ko) 2019-11-01
CN103501774A (zh) 2014-01-08
SI2680834T1 (en) 2018-01-31
LT2680834T (lt) 2018-01-10
IL258357A (en) 2018-05-31
JP6259042B2 (ja) 2018-01-10
EP3766489B1 (en) 2022-03-16
EP2680834A1 (en) 2014-01-08
PL2680834T3 (pl) 2018-03-30
MX374468B (es) 2025-03-06
US20120225950A1 (en) 2012-09-06
JP2018065839A (ja) 2018-04-26
RS56692B1 (sr) 2018-03-30
EA201300988A1 (ru) 2014-06-30
PT2680834T (pt) 2018-01-25
EP3766489A1 (en) 2021-01-20
EA025194B1 (ru) 2016-11-30
CA2828637A1 (en) 2012-09-13
JP2017039756A (ja) 2017-02-23
US20180133174A1 (en) 2018-05-17

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