KR101891951B1 - Mask pack comprising emulsion composition containing peach-extract - Google Patents

Abstract

The present invention provides a mask pack including an emulsion composition. The emulsion composition includes: 1-8 wt% of glycerin; 1-5 wt% of sodium hyaluronate; 1-7 wt% of a peach extract; 0.5-4 wt% of a licorice extract; 1-8 wt% of sodium acetylated hyaluronate; 0.1-2 wt% of hydrolyzed hyaluronic acid; 0.1-3 wt% of hydrolyzed collagen; 0.1-3 wt% of a lemon extract; 0.1-3 wt% of sugar; 0.1-3 wt% of a maple extract; 0.1-3 wt% of extracts of bilberries and leaves thereof; 0.1-3 wt% of a sugar cane extract; 0.1-3 wt% of an orange extract; 0.1-3 wt% of a Portulaca oleracea extract; 0.1-3 wt% of a tea tree extract; 0.1-3 wt% of a bergamot leaf extract; 0.1-3 wt% of bamboo water; 0.1-3 wt% of a camellia flower extract; 0.1-3 wt% of panthenol dipotassium glycyrrhizate; 0.1-3 wt% of allantoin; 0.1-3 wt% of a betaine glyceryl acrylate/acrylic acid copolymer; 0.1-3 wt% of a PVM/MA copolymer; 1-7 wt% of propylene glycol; 0.1-3 wt% of a hydroxy ethyl acrylate/sodium acryloyl dimethyl taurate copolymer; 0.01-0.3 wt% of xanthan gum; 0.05-2 wt% of PEG-60 Hydrogenated castor oil; 0.1-1 wt% of 1,2-hexane diol; 0.1-1 wt% of hydroxyacetophenone; 0.005-0.1 wt% of Disodium EDTA; 0.01-0.2 wt% of spice; and the remaining of purified water.

Description

MASK PACK COMPRISING EMULSION COMPOSITION CONTAINING PEACH-EXTRACT [0002] The present invention relates to a mask pack comprising an emulsion composition containing a peach extract,

The present invention relates to a mask pack comprising an emulsion composition containing peach extract.

In modern society, large amounts of active oxygen are generated by ultraviolet rays and water pollution due to exhaust gas, toxic chemical substances, destruction of ozone layer, etc. Such active oxygen penetrates into human body and causes various side effects. In particular, And the like.

In addition, in recent years, outdoor leisure activities such as golf have been increasing in order to overcome the excessive social and work stress. During the leisure activities in such occasions, the body skin is more easily exposed directly to the above pollution sources, And skin aging can not be avoided. This has a negative effect on the tendency to enjoy outdoor leisure activities more positively and comfortably.

In general, skin plays a primary role in preventing harm from various external factors that interfere with our homeostasis through basic metabolic processes. In other words, while the skin is located at the outermost position of the body, it plays various roles such as protection through physical, chemical and biological barrier functions, body temperature regulating action, sensory action, secretion and excretion action, absorption action, storage action and regeneration action , And most likely to be damaged if sustained external stress is applied. The main causes of external stresses are ultraviolet exposure, exhaust gas, dust, environmental pollutants, heavy metals, temperature changes and microorganisms. These are mainly caused by oxidative stress, reactive oxygen species , ROS), thereby destroying the antioxidant defense system and causing cell damage and death.

On the other hand, a person's skin must have an adequate amount of moisture to appear superficially soft, supple and healthy. This requires that the moisture evaporation be kept low even in a dry environment. When the skin becomes dry, the upper part of the epidermis becomes coarse, dry, and soft. If the dryness of the skin becomes deeper, the keratin is excessively torn or cracked, and in severe cases it is classified as skin disease at all. In dry skin, it has been reported that the binding force between keratinocytes is weakened, the lipid component is changed, and the retention of water content of keratin is decreased.

In addition, since a proper amount of skin moisture is an essential factor for maintaining a normal skin condition, research on skin moisturizing agents for maintaining the moisture content of the skin is continuously carried out. Conventionally developed skin moisturizers can simply moisturize the skin and temporarily maintain the moisture content. However, these moisturizers penetrate deeply into the skin through the epidermis, and there is a very low ability to fix moisture in the stratum corneum which is easy to dry and has a barrier to moisture, so that the skin moisture content is maintained to an appropriate level It has the problem that it is difficult.

On the other hand, a gel type or cream type mask pack containing a cosmetic ingredient and a mask pack using a powder type substance mixed with water are mainly used for skin care, especially facial skin care, for skin care purpose. Methods of using such a mask pack include steps of cleansing the face, applying the functional ingredient, applying or attaching a mask pack comprising a functional ingredient (cosmetic ingredient), and removing the mask pack or sheet mask Lt; / RTI >

As such, the mask pack industry is rapidly developing. However, the development speed of quality is still insufficient compared with the external development speed. Therefore, it is desired to produce an effective mask pack capable of providing effects such as moisturizing, whitening, antioxidation, and wrinkle reduction while reducing the number of times of use of the mask pack.

Korean Patent Publication No. 10-2017-0056148

Disclosure of the Invention The present invention has been conceived to solve the above-mentioned disadvantages of the prior art, and it is an object of the present invention to provide a mask pack which can provide excellent skin moisturizing, antioxidant, whitening, and wrinkle improvement effects only once a week The purpose.

According to the present invention,

1 to 8 wt% of glycerin, 1 to 5 wt% of sodium hyaluronate, 1 to 7 wt% of peach extract, 0.5 to 4 wt% of licorice extract, 1 to 8 wt% of sodium acetylated hyaluronate, 0.1 to 3 wt% of lemon extract, 0.1 to 3 wt% of sugar, 0.1 to 3 wt% of leaf extract, 0.1 to 3 wt% of berry fruit, 0.1 to 3 wt% of leaf extract, 0.1 to 3 wt% of sugar cane extract, 0.1 to 3 wt% of orange extract, 0.1 to 3 wt% of horseradish extract, 0.1 to 3 wt% of tea tree leaf extract, 0.1 to 3 wt of bergamot leaf extract 0.1 to 3 wt% of bamboo water, 0.1 to 3 wt% of camellia extract, 0.1 to 3 wt% of panthenol dipotassium glycyrrhizate, 0.1 to 3 wt% of allantoin, 0.1 to 3 wt% of betaine glyceryl acrylate / acrylic acid copolymer, 3 wt.%, PVEM / MEA copolymer 0.1-3 wt.%, Propylene glycol 1-7 wt.%, Hydroxyethyl methacrylate / 0.1 to 3% by weight of acryloyldimethyltaurate copolymer, 0.01 to 0.3% by weight of xanthan gum, 0.05 to 2% by weight of hydrogenated castor oil, 0.1 to 1% by weight of 1,2-nucleic acid diol, The present invention relates to a mask pack comprising an emulsion composition comprising 0.1 to 1% by weight of a hydroxyacetophenone, 0.005 to 0.1% by weight of disodium iodide, 0.01 to 0.2% by weight of a perfume, and a purified water balance.

The emulsion composition further comprises 0.1 to 5% by weight of an extract obtained by hot-water extracting a mixture of rice hull, hull, buckwheat husk, and husked dried soybeans at a weight ratio of 1: 3: 1 to 3: 1 to 3: And the like.

The emulsion composition may further comprise 0.1 to 3% by weight of a compound represented by the following formula (1) as an emulsifying aid:

[Chemical Formula 1]

In this formula,

n is a natural number of 2 to 10,

a and b are molar fractions, a is 0.5 and b is 0.5;

c and d are mole fractions, c is 0.05 to 0.2, d is 0.8 to 0.95, and c + d is 1.

The mask pack may further include a composition for keratinocare care and a composition for skin cleansing separately from the emulsion composition.

Wherein the mask pack is impregnated with a peeling pad for the keratin care composition; The composition for skin soothing is impregnated with a soft pad; The emulsion composition may have the feature that it is impregnated into the mask pad and sealed separately and contained.

The mask pack of the present invention provides excellent skin moisturizing, antioxidant, whitening, and wrinkle-improving effects by only one use per week.

FIG. 1 is a photograph showing a peeling pad (a) for impregnating the composition for keratin care of the present invention, a soft pad (b) for impregnating the skin soothing composition, and a mask pad (c) for impregnating the emulsion composition to be.
2 is a photograph showing the structure of the mask pack of the present invention.

Hereinafter, the present invention will be described in detail.

The present invention relates to a method for producing a herbal composition comprising 1 to 8 wt% of glycerin, 1 to 5 wt% of sodium hyaluronate, 1 to 7 wt% of peach extract, 0.5 to 4 wt% of licorice extract, 1 to 8 wt% of sodium acetylated hyaluronate, 0.1 to 3% by weight of hydrolyzed collagen, 0.1 to 3% by weight of lemon extract, 0.1 to 3% by weight of sugar, 0.1 to 3% by weight of leaf extract, 0.1 to 3% by weight of the extracts of bilberry and leaf, 0.1 to 3% by weight of sugar cane extract, 0.1 to 3% by weight of orange extract, 0.1 to 3% 0.1 to 3% by weight of panthenol dipotassium glycyrrhizinate, 0.1 to 3% by weight of allantoin, 0.1 to 3% by weight of bamboo water, 0.1 to 3% 0.1 to 3% by weight of a polymer, 0.1 to 3% by weight of a PVEM / MEA copolymer, 1 to 7% by weight of propylene glycol, 0.1 to 3% by weight of sodium acryloyldimethyltaurate copolymer, 0.01 to 0.3% by weight of xanthan gum, 0.05 to 2% by weight of hydrogenated castor oil, 0.1 to 1% by weight of 1,2- , 0.1 to 1% by weight of hydroxyacetophenone, 0.005 to 0.1% by weight of disodium iodide, 0.01 to 0.2% by weight of fragrance, and a purified water balance.

The use of the mask pack once a week provides excellent effects for skin moisturizing, whitening, and wrinkle improvement.

Among these components, the peach extract performs a function of supplying water and imparting a skin light body.

Licorice extracts among the above ingredients provide an excellent effect on skin soothing.

Among these components, hyaluronic acid provides excellent effects on skin moisturization.

Among these ingredients, the lemon extract functions to improve skin vitality.

Among these ingredients, the bilberry extract performs a function of supplying nutrition to the skin.

The sugar cane extract of the above components performs the function of curing the skin tone.

Among these components, the orange extract functions to improve skin vitality.

The marigold extract of the above components performs the function of curing skin tone.

The tea tree leaf extract among the above components performs a skin soothing function.

In the mask pack of the present invention, the emulsion composition is prepared by subjecting a mixture obtained by mixing rice hull, hull, buckwheat husk and peeled dried soybeans at a weight ratio of 1: 3: 1 to 3: 1 to 3: 5% by weight.

The rice hull, hull, buckwheat husk, and husked dried soybean hulls have been found to be grains or fruit husks and are not widely used as active ingredients, but are discarded.

The rice husk contains 35 to 46% of crude fiber, 22 to 5% of soluble saccharide, 13 to 21% of ash, and 2 to 3% of crude protein. It is known that the urine is useful for improving digestion and preventing skin aging. Since the buckwheat husk clears the blood, it can perform the function of preventing the skin trouble.

The above-mentioned peeled dried soybeans are said to protect the intestines and stomachs in the main herbaceous gland, warm the genus, enhance the kidney function, protect the epidermis, and have an effect on boils and hemorrhagic inflammatory diseases. It is known that soybean is excellent for respiratory diseases such as rhinitis, allergic rhinitis, cold, sinusitis, runny nose, sneezing, nasal obstruction and asthma. In addition, it can stimulate growth and strengthens bones, so it helps to grow children. It is effective against skin diseases because of atopy, acne and skin moisturizing effect. It removes wastes and helps constipation and obesity, And it is good for symptom such as sloppy call. In addition, it is excellent for inflammation of liver and boil, and is good for oral mucositis, etc. It is known that it promotes blood circulation, strengthens immunity, excretes toxins in the body and detoxifies.

The emulsion composition may have a characteristic further comprising a compound represented by the following formula (1) as an emulsifying aid:

[Chemical Formula 1]

In this formula,

n is a natural number of 2 to 10,

a and b are molar fractions, a is 0.5 and b is 0.5;

c and d are mole fractions, c is 0.05 to 0.2, d is 0.8 to 0.95, and c + d is 1.

In the block copolymer of poly-D, L-lactic acid-co-glycolic acid and polyacrylic acid substituted with a diisocyanate compound as the emulsifying aid, poly-D, L-lactic acid-co- glycolic acid is included as a hydrophobic part, Polyacrylic acid substituted with an isocyanate compound is included as a hydrophilic moiety.

In the above, polyacrylic acid substituted by poly-D, L-lactic acid-co-glycolic acid (Formula 2) and diisocyanate compound (Formula 3 below) can be produced by the combination of an isocyanate group and a hydroxyl group of a carboxyl group. a block copolymer of polyacrylic acid substituted with -co-glycolic acid and diisocyanate compound is formed.

(2)

(3)

The poly-D, L-lactic acid-co-glycolic acid preferably has a weight average molecular weight of 1,000 to 80,000, and the copolymer of polyacrylic acid substituted with the diisocyanate compound has a weight average molecular weight of 100 to 10,000. Are preferred for the formation of nanoparticle emulsions.

The average particle diameter of the copolymer is preferably from 10 to 100 nm. When such a particle size is used, penetration into the skin and collection of the active ingredient are excellent. The thus obtained copolymer is remarkably stable in an aqueous solution as compared with a low molecular weight micelle. This characteristic of the copolymer means that the water-in-oil type nanoparticulate emulsion cosmetic composition of the present invention can be stored in a stable state for a long period of time and can maintain its structure for a considerable period of time in the body.

The emulsion composition of the present invention is not particularly limited as long as it has a low viscosity to such an extent that the desired dispersibility can be achieved in order to increase the content of the nanoemulsion inner layer and effectively deliver the active ingredient. For example, the emulsion composition may have a viscosity of 5000 cps or less, 3000 cps or less, more specifically 2000 cps or less. The 'low viscosity' emulsion contains all of the emulsions belonging to the aforementioned viscosity ranges from when the viscosity can not be measured experimentally because the viscosity is very small. When the viscosity is not experimentally measured, the viscosity range is 0 , For example from 0 to 5000 cps, specifically from 1 to 3000 cps, more specifically from 5 to 2000 cps.

The emulsion is nano-sized and is not particularly limited as long as it can produce an emulsion having a low viscosity while improving the stability of the emulsion. For example, the emulsion may have an average size of 250 nm or less, specifically 200 nm or less.

The emulsion may have any size falling within the above average size range, but may have an average size of, for example, 10 to 250 nm, specifically 20 to 200 nm.

The mask pack of the present invention may further comprise a composition for keratin care and a composition for skin soothing, separately from the emulsion composition.

Wherein the composition for keratin care comprises 1 to 8 wt% of glycerin, 1 to 5 wt% of sodium hyaluronate, 0.5 to 4 wt% of methylpropanediol-modified alcohol, 1 to 7 wt% of peach extract, 0.5 to 4 wt% 1 to 8% by weight of sodium acetylated hyaluronate, 0.1 to 2% by weight of hydrolized hyaluronic acid, 0.1 to 3% by weight of hydrolized collagen, 0.1 to 3% by weight of lemon extract, 0.1 to 3% by weight of the leaves extract, 0.1 to 3% by weight of the leaves extract, 0.1 to 3% by weight of the extract of Bilberry fruit and leaf, 0.1 to 3% by weight of sugar cane extract, 0.1 to 3% 0.1 to 3 wt% of tea tree leaf extract, 0.1 to 3 wt% of lactobionic acid, 0.1 to 3 wt% of sodium lactate, 0.1 to 3 wt% of glycolic acid, 0.1 to 3 wt% of dipotassium glycyrrhizate, 0.1 to 3% by weight of allantoin, 0.05 to 2% by weight of a fat-60 hydrogenated castor oil, 0.1 to 1% by weight of a 1,2-nucleic acid diol, Non 0.1-1 wt.%, Disodium is preferred to include this in a dithiol 0.005 ~ 0.1% by weight, 0.01% to 0.2% by weight perfume, and the remaining amount of purified water, and;

Wherein the skin-soothing composition comprises 1 to 8% by weight of methylpropanediol glycerin, 1 to 5% by weight of sodium hyaluronate, 1 to 7% by weight of peach extract, 0.5 to 4% by weight of licorice extract, sodium acetylated hyaluronic acid 0.1 to 3% by weight of hydrolyzed collagen, 0.1 to 3% by weight of lemon extract, 0.1 to 3% by weight of sugar, 0.1 to 3% by weight of the extracts of Bilberry fruit and leaf extract, 0.1 to 3% by weight of sugar extract, 0.1 to 3% by weight of orange juice extract, 0.1 to 3% 0.1 to 3% by weight of bergamot leaf extract, 0.1 to 3% by weight of bamboo water, 0.1 to 3% by weight of camphor flower extract, 0.1 to 3% by weight of panthenol dipotassium glycyrrhizate, 0.1 to 3% by weight of allantoin, 0.1 to 3% by weight of fumed cellulose, 0.1 to 3% by weight of glyceryl polyacrylate, 0.1 to 3% by weight of citric acid, 0.1 to 3% 0.1 to 1% by weight of 1,2-nucleic acid diol, 0.1 to 1% by weight of hydroxyacetophenone, 0.005 to 0.1% by weight of disodium dipentaerythritol, 0.05 to 2% by weight of hydrogenated castor oil, 0.01 to 0.2% by weight of a perfume, and a purified water balance.

In the mask pack of the present invention, the composition for keratin care is impregnated with a peeling pad as shown in Fig. 1; The composition for skin soothing is impregnated with a soft pad; The emulsion composition may be impregnated into the mask pads and sealed and contained separately.

The material for the peeling pad, the soft pad, and the mask pad may be any material known in the art without limitation. For example, the pad for peeling may be a nonwoven fabric having a fine surface as shown in Fig. 1, and as the soft pad, a pad having an embossed surface made of a surface may be used.

The mask pack of the present invention comprises: a peeling pad impregnated with a composition for keratin care; A soft pad impregnated with a composition for skin soothing; And the mask pads impregnated with the emulsion composition are each sealed individually and packaged in one sealed pack.

Their methods of use can be used according to known methods for keratinic care, skin soothing, and the skin contact method of a moisturizing mask pad.

Hereinafter, the present invention will be described in more detail by way of examples. However, the following examples are intended to further illustrate the present invention, and the scope of the present invention is not limited by the following examples. The following examples can be appropriately modified and changed by those skilled in the art within the scope of the present invention.

Manufacturing example  1: chaff, Julie , Buckwheat husks, and Peeled  Arid soybean Hot water extract  Produce

Rice hull, husk, buckwheat husks, and peanut dried soybeans were mixed in an amount of 300 g each, put into 12 liters of distilled water, and extracted at 100 ° C for 24 hours to prepare a hot water extract.

Manufacturing example  2: Poly - D, L - lactic acid-co- Glycolic acid Diisocyanate  Substituted with a compound Of polyacrylic acid  Preparation of block copolymers

(1) Preparation of polyacrylic acid substituted with diisocyanate compound

40 parts by weight of acrylic acid was added to a 1 L reactor equipped with a cooling device so that nitrogen gas was refluxed and the temperature thereof was easily controlled. 60 parts by weight of ethyl acetate (EAc; ethyl acetate) was poured into the solvent, and nitrogen gas was purged for 30 minutes. The temperature was maintained at 60 占 폚 and 0.1 part by weight of AIBN (azobisisobutyronitrile) as a reaction initiator was added and reacted for 3 hours to prepare an acrylic acid polymer having a weight average molecular weight of 1,500.

100 parts by weight of ethyl acetate (EAc; ethyl aceate) was added to a 1 L reactor equipped with a cooling device to easily regulate the temperature of the reflux of the nitrogen gas. 100 parts by weight of the acrylic acid polymer solid component prepared above and 100 parts by weight of hexamethylene di 10 parts by weight of isocyanate, 54 mg of magnesium trifluorosulfonate, 0.5 part by weight of lonol and 0.15 part by weight of Tinuvin were added. And heated to 110 deg. Heating was carried out for 15 hours to prepare acrylic acid substituted with hexamethylene diisocyanate.

(2) Preparation of block copolymer of poly-D, L-lactic acid-co-glycolic acid and polyacrylic acid substituted with diisocyanate compound

100 ml of dimethylformamide and 290 mg of N, N-carbonyldiimidazole (CDI) were added to the reaction vessel and stirred. To this was added 20 g of poly-D, L-lactic acid-co-glycolic acid (RG502, Boehringer Ingelheim, Germany) having a number average molecular weight of 11,000 to obtain a hydroxyaldehyde group of poly-D, L-lactic acid- Lt; / RTI > 0.5 mg of lonol, 0.15 mg of Tinuvin and 25 g of polyacrylic acid having a number average molecular weight of 2,000 prepared in Preparation Example 1 were added to the solution and heated to 110 ° C. The mixture was heated for 15 hours, filtered through a nylon filter having a pore size of 0.45 micrometer, dispersed in tertiary distilled water, and then dialyzed to remove unreacted materials and reaction reagents to prepare a block copolymer.

Example  One: emulsion  Preparation of composition

Each component was divided into oil phase and water phase according to the composition shown in the following Table 1, heated to 70 to 90 占 폚, and then an oil phase was added to the water phase and stirred with a homomixer to prepare an O / W emulsion.

ingredient Content (% by weight) glycerin 5 Sodium hyaluronate 3 Peach extract 4 Licorice extract 2 Sodium acetylated hyaluronate 4 Hydrolyzed hyaluronic acid 0.5 Hydrolized Collagen One Lemon extract One Sugar 0.5 Maple extract 0.5 Bilberry fruit and leaf extract 0.5 Sugar cane extract One Orange extract One Marchia extract 2 Tea tree leaf extract 0.5 Bergamot leaf extract 0.5 Bamboo water One Camellia extract 0.5 Panthenol dipotassium glycyrrhizate One Allantoin 0.5 Betaine glyceryl acrylate / acrylic acid copolymer One PVEM / MEG copolymer One Propylene glycol 2 Hydroxyethyl methacrylate / sodium acryloyldimethyltaurate copolymer One Xanthan gum 0.06 PIGGY-60 Hydrogenated Castor Oil 0.2 1,2-nucleic acid diol 0.4 Hydroxyacetophenone 0.3 Disodium iodide 0.2 Spices 0.04 Purified water Balance Sum 100

Example  2: emulsion  Preparation of composition

An emulsion composition was prepared in the same manner as in Example 1 except that 3% by weight of the emulsifying auxiliary represented by the formula (1) prepared in Preparation Example 2 was further added to the composition of Example 1 above.

Example  3 For Keratin Care  Preparation of composition

Each component was mixed according to the composition shown in Table 2 below to prepare a composition for keratin care.

ingredient Content (% by weight) glycerin 5 Sodium hyaluronate 3 Methylpropane diol denatured alcohol 2 Peach extract 4 Licorice extract 2 Sodium acetylated hyaluronate 4 Hydrolyzed hyaluronic acid 0.5 Hydrolized Collagen One Lemon extract One Sugar 0.5 Maple extract 0.5 Bilberry fruit and leaf extract 0.5 Sugar cane extract One Orange extract One Marchia extract 2 Tea tree leaf extract 0.5 Lactobionic Acid 0.5 Sodium lactate, One Glycolic acid, 0.5 Dipotassium glycyrrhizate One Allantoin 0.5 PIGGY-60 Hydrogenated Castor Oil 0.2 1,2-nucleic acid diol 0.4 Hydroxyacetophenone 0.3 Disodium iodide 0.2 Spices 0.04 Purified water Balance Sum 100

Example  4: For soothing skin  Preparation of composition

Each component was mixed according to the composition shown in Table 3 below to prepare a composition for skin soothing.

ingredient Content (% by weight) Methylpropanediol glycerin 5 Sodium hyaluronate 3 Peach extract 4 Licorice extract 2 Sodium acetylated hyaluronate 4 Hydrolyzed hyaluronic acid 0.5 Hydrolized Collagen One Lemon extract One Sugar 0.5 Maple extract 0.5 Bilberry fruit and leaf extract 0.5 Sugar cane extract One Orange extract One Marchia extract 2 Tea tree leaf extract 0.5 Bergamot leaf extract 0.5 Bamboo water One Camellia extract 0.5 Panthenol dipotassium glycyrrhizate One Allantoin 0.5 Hydroxyethyl cellulose One Glyceryl polyacrylate 0.5 Citric acid One Sodium citrate 0.5 PIGGY-60 Hydrogenated Castor Oil 0.2 1,2-nucleic acid diol 0.4 Hydroxyacetophenone 0.3 Disodium iodide 0.2 Spices 0.04 Purified water Balance Sum 100

Example  5: emulsion Impregnation  Manufacture of mask pads

The emulsion compositions prepared in Examples 1 and 2 were immersed in a nonwoven mask pad to prepare an emulsion-impregnated mask pad.

Example  6: Horny Care  For filling Peelling ) Manufacture of pads

The composition for keratinocyte care prepared in Example 2 was impregnated in a nonwoven fabric-filling pad to prepare a pad for keratin-care filling.

Example  7: For soothing skin  Manufacture of soft pads

The skin-soothing composition prepared in Example 3 was impregnated with a cotton soft pad to prepare a soothing soft pad.

Test Example  One: emulsion  Of the composition Emulsion  Measurement of particle size and stability of nano emulsion by particle size change

The sizes of the particles of the water-in-oil type nanoparticle emulsion cosmetic compositions of the present invention obtained according to Examples 1 and 2 were measured using mastersizer 2000 (Mastersizer 2000, Malvern Instrument, UK) by the dynamic light scattering principle, The results are shown in Table 4 below. At this time, the measurement of the particle size was carried out under the following conditions by diluting the nano emulsion diluted solution with purified water to have a turbidity of 10-20%.

Measurement time: 2 minutes, the number of measurements per second: 5 × 10 ^3, temperature: 20 ℃, viscosity: 0.89 centipoise, particle refractive index: 1.4, refractive index of dispersion medium: 1.33

Particle size measurements were made after one day of manufacture and after storage for 6 months at 40 ° C for two times to evaluate the thermodynamic stability of the nanoemulsion after long term storage at high temperature.

Test Example  2. Stability of emulsification by visual observation

The emulsion stability of the water-in-oil type nano-emulsion cosmetic compositions obtained in Examples 1 and 2 was evaluated by naked eye observation and evaluation as follows. The results are shown in Table 4 below.

The emulsified state of the composition of Example 1 and Example 2 after storage at room temperature (about 25 ° C) and at 40 ° C for 6 months was compared with the state immediately after preparation. The unstable state was observed by visual observation as sedimentation, separation, drainage, creaming, and union. The emulsion stability is evaluated as a percentage (%) of the stable part excluding the unstable part as a whole.

Emulsion stability (%) = [(total - unstable part) / total] × 100%

Nanoparticle emulsion
Cosmetic composition Particle Size (nm) Increase in particle size (%) Stability of emulsification by visual observation (%) After the preparation, storage at room temperature for 1 day After storage for 6 months at 40 ° C Example 1 79 82 3.8 94 Example 2 76 78 2.6 96

As can be seen in Table 4, the emulsion stabilizing composition of the present invention has excellent stability as a nanoparticle emulsion. In particular, when the emulsifying aid represented by the general formula (1) is used, the emulsion is more stable.

Test Example  3: Skin safety

The skin safety was evaluated by skin-spiking experiments on the compositions prepared in Examples 1 to 4. 15 patients (female: 10, male: 5) who had experienced skin adverse effects due to cosmetics were applied to the back of the patient, and after 48 hours, the papilla was removed and after 1 hour to 2 hours, The results were also evaluated after 72 hours or 96 hours. The results are shown in Table 5 below.

Number of positive responders % Example 1 [ 0 0 Example 2 [ 0 0 Example 3 [ 0 0 Example 4 The emulsion composition 0 0

As shown in Table 5, the compositions of the present invention have excellent skin safety.

Test Example  4: Antioxidative efficacy evaluation ( ABTS  assay)

1) Sample information

(1) Filtered with 0.45μm filter

(2) Sample preparation: The composition of Example 1 was diluted 10 times and used

2) Evaluation method

(1) Experimental material

- 7 mM solution of ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid)

- Potassium persulfate (K2S2O8) 140 mM solution

- Standard solution (Ascorbic acid 80 g / ml, 40 g / ml, 20 g / ml, 10 g / ml)

- 96 well plate

- ELISA reader

(2) Procedure of experiments

a. ABTS + Stock solution was prepared and diluted such that the absorbance (734 nm) value was 0.68 ~ 0.72 after standing for 24 hours.

b. Add 20 μl of sample and standard solution to 96 well plate

c. Add 180 μl of ABTS + solution per well

d. Measurement of absorbance (734 nm) after 10 min reaction at room temperature in dark room

3) Antioxidant efficacy evaluation result (ABTS assay)

As a result of the antioxidative efficacy evaluation (ABTS assay), the 10-fold dilution of the composition of Example 1 exhibited antioxidative activity equal to or higher than that of 40 μg / ml of representative antioxidant, ascorbic acid.

Test Example  5: Evaluation of whitening efficacy ( Melanogenesis  inhibition assay)

1) Sample information

(1) Filtered with 0.45μm filter

(2) Sample preparation: The composition of Example 1 was diluted 10 times and used

2) Evaluation method

(1) Experimental material

- melanin-producing cell line B16F10 cell (ATCC CRL-6475)

- DMEM medium (+ 10% FBS, 1% Antibiotics)

- Positive control (Arbutin 2 mg / ml)

- 37 ° C CO2 incubator

- PBS (Phosphate Buffered Saline) pH 7.4

- 50 uM α-MSH (α-Melanocyte Stimulating Hormone) stock solution

- Trypsin-EDTA

- 1 M NaOH (+ 10% DMSO)

- Cell Counting Kit-8 (Manufacturer: Dojindo)

- Cell culture flask (25 cm 2, 75 cm 2), 96 well plate

(2) Procedure of experiments

a. B16F10 cells were cultured in DMEM medium (+ 10% FBS, 1% Antibiotics)

b. The cultured cells were divided into 2 × 10 5 cells / flask in a cell culture flask (25 cm 2), cultured for 24 hours

c. After removing the culture solution, 4.5 ml of medium containing α-MSH (final concentration 50 nM) and 0.5 ml of sample were added and cultured for 48 hours (*

d. After removal of the culture medium, the cells were exchanged with a fresh medium, and cytotoxicity was measured using the CCK-8 assay. Only the cell viability (% of control) ≧ 80%

e. Cells were recovered using trypsin-EDTA, and after removing the culture solution, 1 M NaOH

(+ 10% DMSO) solution to dissolve cells and obtain intracellular melanin

f. Melanin-soluble lysate was used to measure the absorbance at 490 nm to calculate the amount of melanin synthesis (%) versus the number of cells

3) Melanogenesis inhibition assay

As a result of the cytotoxicity test on B16F10 cells of the 10-fold dilution of the composition of Example 1, no toxicity was observed, and as a result of the melanogenesis inhibition assay, the amount of melanin produced by the α-MSH group alone was 100% And about 85% in the group treated with 10 times dilution.

Test Example  6: Wrinkle improvement effect evaluation

Ten women aged 40 years old were selected and the mask pack of the present invention was used once a week for 4 weeks, and the wrinkle improving effect was evaluated. The use of mask padding was performed in the following order. First, the face was wiped using the pad for keratin care filling produced in Example 6, and the face was wiped once more using the soft-skin softening pad prepared in Example 7. Thereafter, Impregnated mask pad was brought into close contact with the face to carry out the mask pack. After 30 minutes, the skin was cleansed.

After 4 weeks, the degree of relieving of the wrinkles was evaluated by visual and photographic judgment (no improvement, slight improvement, moderate improvement, and significant improvement in four stages) and is shown in Table 4 below.

Total number of people No improvement Slight improvement Improvement of severity A significant improvement Use of the mask pack of the present invention 10 people 0 6 3 One

As shown in Table 6, the mask pack of the present invention exhibited a very excellent wrinkle-reducing effect.

Claims (6)

1 to 8 wt% of glycerin, 1 to 5 wt% of sodium hyaluronate, 1 to 7 wt% of peach extract, 0.5 to 4 wt% of licorice extract, 1 to 8 wt% of sodium acetylated hyaluronate, 0.1 to 3 wt% of lemon extract, 0.1 to 3 wt% of sugar, 0.1 to 3 wt% of leaf extract, 0.1 to 3 wt% of berry fruit, 0.1 to 3 wt% of leaf extract, 0.1 to 3 wt% of sugar cane extract, 0.1 to 3 wt% of orange extract, 0.1 to 3 wt% of horseradish extract, 0.1 to 3 wt% of tea tree leaf extract, 0.1 to 3 wt of bergamot leaf extract 0.1 to 3 wt% of bamboo water, 0.1 to 3 wt% of camellia extract, 0.1 to 3 wt% of panthenol dipotassium glycyrrhizate, 0.1 to 3 wt% of allantoin, 0.1 to 3 wt% of betaine glyceryl acrylate / acrylic acid copolymer, 3 wt.%, PVEM / MEA copolymer 0.1-3 wt.%, Propylene glycol 1-7 wt.%, Hydroxyethyl methacrylate / 0.1 to 3% by weight of acryloyldimethyltaurate copolymer, 0.01 to 0.3% by weight of xanthan gum, 0.05 to 2% by weight of hydrogenated castor oil, 0.1 to 1% by weight of 1,2-nucleic acid diol, Wherein the emulsion composition comprises 0.1 to 1% by weight of a hydroxyacetophenone, 0.005 to 0.1% by weight of disodium iodide, 0.01 to 0.2% by weight of a perfume, and a purified water balance. The method according to claim 1,
The emulsion composition further comprises 0.1 to 5% by weight of an extract obtained by hot-water extracting a mixture of rice hull, hull, buckwheat husk, and husked dried soybeans at a weight ratio of 1: 3: 1 to 3: 1 to 3: Wherein the mask pack is a mask pack. The method according to claim 1,
Wherein the emulsion composition further comprises 0.1 to 3% by weight of a compound represented by the following formula (1) as an emulsifying aid:
[Chemical Formula 1]

In this formula,
n is a natural number of 2 to 10,
a and b are molar fractions, a is 0.5 and b is 0.5;
c and d are mole fractions, c is 0.05 to 0.2, d is 0.8 to 0.95, and c + d is 1. The method according to claim 1,
Wherein the mask pack further comprises a composition for keratinocyte care and a composition for skin soothing, separately from the emulsion composition. 5. The method of claim 4,
Wherein the composition for keratin care comprises 1 to 8 wt% of glycerin, 1 to 5 wt% of sodium hyaluronate, 0.5 to 4 wt% of methylpropanediol-modified alcohol, 1 to 7 wt% of peach extract, 0.5 to 4 wt% 1 to 8% by weight of sodium acetylated hyaluronate, 0.1 to 2% by weight of hydrolized hyaluronic acid, 0.1 to 3% by weight of hydrolized collagen, 0.1 to 3% by weight of lemon extract, 0.1 to 3% by weight of the leaves extract, 0.1 to 3% by weight of the leaves extract, 0.1 to 3% by weight of the extract of Bilberry fruit and leaf, 0.1 to 3% by weight of sugar cane extract, 0.1 to 3% 0.1 to 3 wt% of tea tree leaf extract, 0.1 to 3 wt% of lactobionic acid, 0.1 to 3 wt% of sodium lactate, 0.1 to 3 wt% of glycolic acid, 0.1 to 3 wt% of dipotassium glycyrrhizate, 0.1 to 3% by weight of allantoin, 0.05 to 2% by weight of a fat-60 hydrogenated castor oil, 0.1 to 1% by weight of a 1,2-nucleic acid diol, Non 0.1-1% by weight of the disodium dithiane A 0.005 ~ 0.1% by weight, comprising a perfume 0.01% to 0.2% by weight, and purified water balance;
Wherein the skin-soothing composition comprises 1 to 8% by weight of methylpropanediol glycerin, 1 to 5% by weight of sodium hyaluronate, 1 to 7% by weight of peach extract, 0.5 to 4% by weight of licorice extract, sodium acetylated hyaluronic acid 0.1 to 3% by weight of hydrolyzed collagen, 0.1 to 3% by weight of lemon extract, 0.1 to 3% by weight of sugar, 0.1 to 3% by weight of the extracts of Bilberry fruit and leaf extract, 0.1 to 3% by weight of sugar extract, 0.1 to 3% by weight of orange juice extract, 0.1 to 3% 0.1 to 3% by weight of bergamot leaf extract, 0.1 to 3% by weight of bamboo water, 0.1 to 3% by weight of camphor flower extract, 0.1 to 3% by weight of panthenol dipotassium glycyrrhizate, 0.1 to 3% by weight of allantoin, 0.1 to 3% by weight of fumed cellulose, 0.1 to 3% by weight of glyceryl polyacrylate, 0.1 to 3% by weight of citric acid, 0.1 to 3% 0.1 to 1% by weight of 1,2-nucleic acid diol, 0.1 to 1% by weight of hydroxyacetophenone, 0.005 to 0.1% by weight of disodium dipentaerythritol, 0.05 to 2% by weight of hydrogenated castor oil, 0.01 to 0.2% by weight of a perfume, and purified water balance. 6. The method of claim 5,
The composition for keratin care is impregnated with a peeling pad; The composition for skin soothing is impregnated with a soft pad; Wherein the emulsion composition is impregnated into a mask pad and sealed and contained separately.

Images