KR101862231B1 - Cosmetic composition for preventing near infrared ray containing extract of ganoderma lucidum - Google Patents

Abstract

The present invention relates to the use of Ganoderma lucidum ) extract, wherein the cosmetic composition of the present invention can prevent near infrared rays from being reflected by heat aging.

Description

TECHNICAL FIELD [0001] The present invention relates to a cosmetic composition for a near-infrared ray shielding containing a Ganoderma lucidum extract,

The present invention relates to the use of Ganoderma lucidum ) extract, wherein the cosmetic composition of the present invention can prevent near infrared rays from being reflected by heat aging.

A variety of physical and chemical changes occur in human skin during the aging process. The cause of this phenomenon is divided into intrinsic aging and photo-aging. Skin aging can be caused by activation of free radicals due to ultraviolet rays, stress, disease states, environmental factors, wounds, or aging. When such conditions are intensified, the antioxidant defense network existing in the living body is destroyed, And tissues to promote adult diseases and aging. More specifically, lipids, proteins, polysaccharides and nucleic acids, which are major constituents of the skin, are oxidized to destroy skin cells and tissues, resulting in skin aging.

Ultraviolet rays have shorter wavelength than visible light and are known to be one of the causes of skin aging. Many studies have been conducted to develop a product for blocking ultraviolet rays. However, the influence of infrared rays on skin aging has been recently described by the concept of heat aging and photoaging.

Although the main cause of heat aging and photo-aging is known as ultraviolet rays, it is known that infrared rays of 780 to 3000 nm wavelength, which is not visible in human eyes adjacent to a red band in the recent electromagnetic wave spectrum, cause skin aging (Kim, MS. et al. "Infrared exposure induces an angiogenic switch in human skin that is partially mediated by heat." British Journal of Dermatology 155.6 (2006): 1131-1138).

Most of the cosmetic ingredients for anti-aging properties are organic and inorganic ultraviolet shielding components, and there is no material having a near-infrared reflection effect from natural ingredients. Accordingly, the present invention aims to investigate a cosmetic material for preventing heat aging which has a near-infrared reflection effect from natural materials.

Korean Patent No. 10-1275351 discloses a cosmetic composition for blocking near-infrared rays or infrared rays containing at least one selected from the group consisting of an amine, an amide and a polyol as an active ingredient.

The present inventors measured the reflectance of a sample of natural material by using a near infrared spectrometer and found that Ganoderma lucidum ) extract in the near-infrared region, thereby completing the present invention.

The present invention relates to a cosmetic composition for blocking near-infrared rays containing Ganoderma lucidum extract.

Preferably, the cosmetic composition is characterized by reflecting the wavelength in the heat or near infrared region.

Preferably, the cosmetic composition is characterized by reflecting a wavelength region of 800 to 1,300 nm.

Preferably, the cosmetic composition has an effect of lowering the skin temperature.

Preferably, the Ganoderma lucidum extract is extracted with an extraction solvent selected from the group consisting of water, 1-4 anhydrous or hydro-lower alcohols, acetone, ethyl acetate, butyl acetate and 1,3-butylene glycol, .

Preferably, the cosmetic composition is in the form of a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, Characterized in that it has a formulation to be selected.

The present invention relates to the use of Ganoderma lucidum ) as an active ingredient. The effective ingredients of the cosmetic composition of the present invention, ganoderma lucidum ) extract is a natural, near-infrared reflective material that reduces the temperature of the skin and has excellent anti-aging effect.

1 is a graph showing a near-infrared blocking effect of Ganoderma lucidum extract.
Fig. 2 is a graph showing the cooling effect of the prescription example 2 and the comparative prescription example 1. Fig.

Unless defined otherwise, all technical terms used in the present invention have the following definitions and are consistent with the meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Also, preferred methods or samples are described in this specification, but similar or equivalent ones are also included in the scope of the present invention. The contents of all publications referred to herein are incorporated herein by reference. The term " drug " is used in reference to a reference amount, level, value, number, frequency, percentage, dimension, size, amount, weight, or length of 30, 25, 20, 25, 10, 9, 8, 7, 6, Level, value, number, frequency, percentage, dimension, size, quantity, weight or length of a sample,

Throughout this specification, the words " comprising " and " comprising ", unless the context clearly requires otherwise, include the steps or components, or groups of steps or elements, And that they are not excluded.

The ganoderma lucidum used in the present invention lucidum ) is a mushroom of the mushroom spruce root, which is widely distributed all over the world and is mainly grown in the root and root of broad-leaved trees. It is a year-old mushroom that grows from summer to fall, and is characterized by lacquer-like lacquer on the surface of shrubs and sacks. The efficacy of Ganoderma lucidum in one room has been used for mental and physical stability, supplementation of mere blood, cough relief, nervous breakdown, relieving insomnia, and recent researches on cancer have been carried out. .

Ganoderma lucidum according to the present invention (Ganoderma lucidum ) extract may be prepared using conventional solvents known in the art, that is, under the conditions of ordinary temperature and pressure, preferably (a) water, Propanol and butanol), propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, hexane (B) a supercritical extraction method by depressurization with carbon dioxide and a high temperature, (c) an ultrasonic extraction method, or (d) a fermentation step. In the present invention, a solvent extraction method using an extraction solvent is preferably used.

In the present invention, Ganoderma lucidum ) extracts can be used in a variety of extraction solvents, for example, water, anhydrous or lower alcohols having 1-4 carbon atoms (e.g., methanol, ethanol, propanol and butanol), propylene glycol, 1,3-butylene glycol, glycerin , At least one extraction solvent selected from the group consisting of acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, hexane and mixtures thereof, preferably 70% (v / v) ethanol or water, and most preferably 70% (v / v) ethanol. On the other hand, the ganoderma It is obvious to those skilled in the art that lucidum extract can be obtained not only by the above-mentioned extraction solvent but also by using other extraction solvent, which exhibits substantially the same effect. In addition, the Ganoderma lucidum extract of the present invention includes extracts obtained by the conventional extraction and fermentation as well as extracts obtained by the above-mentioned extraction solvents. For example, decompression by carbon dioxide, extraction by supercritical extraction with high temperature, extraction by extraction using ultrasound, separation by ultrafiltration membrane with constant molecular weight cutoff value, various chromatography (size, charge, hydrophobic or affinity And the active fraction obtained through various purification and extraction methods, such as an extract obtained by fermentation products using natural or various microorganisms, are also included in the extract of the present invention.

Meanwhile, the cosmetic composition of the present invention may contain, as an active ingredient, the components commonly used in cosmetic compositions in addition to the above-mentioned Ganoderma lucidum extract, and may contain conventional additives such as antioxidants, stabilizers, solubilizers, vitamins, , And a carrier.

Meanwhile, the cosmetic composition of the present invention may be prepared in any formulations conventionally produced in the art, and examples thereof include solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, Cleansing, oil, powder foundation, emulsion foundation, wax foundation, and spray. However, the present invention is not limited thereto. More specifically, it can be manufactured in the form of a soft lotion, a convergent lotion, a nutritional lotion, a nutritional cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder.

When the formulation of the cosmetic composition of the present invention is a paste, a cream or a gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide Can be used.

When the formulation of the cosmetic composition of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component, Propane / butane, or dimethyl ether. ≪ RTI ID = 0.0 >

When the formulation of the cosmetic composition of the present invention is a solution or an emulsion, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate , Propylene glycol, 1,3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

When the formulation of the cosmetic composition of the present invention is in the form of a suspension, the carrier component may include water, a liquid diluent such as ethanol or propylene glycol, ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester Suspending agent, microcrystalline cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the cosmetic composition of the present invention is a surfactant-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, Fatty acid amide ether sulfate, alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

When the cosmetic composition of the present invention is a soap, a surfactant-containing cleansing formulation or a surfactant-free cleansing formulation, it may be applied to the skin and then wiped off, washed or rinsed with water. As a specific example, the soap is liquid soap, powdered soap, solid soap and oil soap, and the surfactant-containing cleansing formulation is a cleansing foam, a cleansing water, a cleansing towel and a cleansing pack, , Cleansing lotion, cleansing water and cleansing gel, but is not limited thereto.

On the other hand, the cosmetic process of the present invention refers to all cosmetic processes using the cosmetic composition of the present invention. That is, all methods known in the art using a cosmetic composition belong to the cosmetic method of the present invention. The cosmetic composition of the present invention may be used alone or in combination, or may be used in combination with other cosmetic compositions other than the present invention. In addition, the cosmetic composition according to the present invention can be used according to a conventional method of use, and may be used in a different number of times depending on the skin condition or taste of the user.

Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are intended to further illustrate the present invention, and the scope of the present invention is not limited to the following examples.

Manufacturing example  1 - Ganoderma lucidum ( Ganoderma lucidum ) Preparation of extract

A shrub of ganoderma ( Ganoderma lucidum ) was refluxed with 70% (v / v) ethanol aqueous solution for 3 hours each time for 5 hours, cooled, and filtered through Whatman # 4 filter paper. The filtered extract was concentrated under reduced pressure and freeze-dried at 50 DEG C or lower.

Hereinafter, the present invention will be described in detail with reference to the following Examples and Experimental Examples. However, the present invention is described in detail with reference to the following Examples and Experimental Examples, and the scope of the present invention is not limited thereto.

Experimental Example  One - Near infrared  Near Infrared spectrometer measurement

Near infrared rays are near infrared rays and visible rays. They are in the range of about 800nm to 2500nm. They are the infrared rays nearest to the sun's radiant heat in the infrared region. They are short wavelength rays that transmit heat waves only to the object without heating the air.

The near-infrared blocking ability of the Ganoderma lucidum extract of Preparation Example 1 was measured. More specifically, MPA Near Infrared Spectrometer (Bruker) was used. The sample was dissolved in a liquid solvent free from interference of the sample and measured using Reflection mode.

The measurement results are shown in Fig. 1 and Table 1, and the x-axis shows the wavelength (nm). Referring to FIG. 1 and Table 1, it can be judged that the more the wavelength is reflected in the infrared region, the better the infrared blocking ability.

In FIG. 1, the near-infrared reflectance of about 0.25 at 1100 nm, which is the wavelength of the near infrared region, was confirmed to be effective for blocking the near-infrared rays of the Ganoderma lucidum extract of the present invention.

Name of sample Sample concentration reflectivity
(%, 1100 nm) reflectivity
(%, 1620 nm) Production Example 1 10% 0.024 0.009

Hereinafter, formulation examples of the composition according to the present invention will be described, but they can be applied to various formulations, which are not intended to limit the present invention but merely to illustrate the present invention.

Prescription example  1 - Lotion

Table 2 shows the prescription examples of cosmetic lotion containing cosmetic ingredients containing Ganoderma lucidum extract.

ingredient Content (unit:% by weight) Ganoderma lucidum extract (Preparation Example 1) 2 glycerin 5 1,3-butylene glycol 3 PIZZY 1500 One Allantoin 0.1 DL-Panthenol 0.3 EDTA-2Na 0.02 Benzophenone-9 0.04 Sodium hyaruronate 5 ethanol 10 Octidodeces-16 0.2 Polysorbate 20 0.2 Preservative, fragrance, pigment a very small amount Distilled water Balance Sum total 100

Prescription example  2 - Cream

Table 3 shows the prescription examples of the cream in cosmetics containing Ganoderma lucidum extract.

ingredient Content (unit:% by weight) Ganoderma lucidum extract (Preparation Example 1) 3 Pro-type glycerin monostearate 2 Cetearyl alcohol 2.2 Stearic acid 1.5 Wax One Polysorbate 60 1.5 Sorbitan stearate 0.6 Hardened vegetable oil One Squalane 3 Mineral oil 5 Trioctanoin 5 Dimethicone One Sodium magnesium silicate 0.1 glycerin 5 Betaine 3 Triethanolamine One Sodium hyaruronate 4 Preservative, fragrance, pigment a very small amount Distilled water Balance Sum 100

Prescription example  3 - Essence

Table 4 shows the prescription examples of essences in cosmetics containing Ganoderma lucidum extract.

ingredient Content (unit:% by weight) Ganoderma lucidum extract (Preparation Example 1) 3 glycerin 10 Betaine 5 PIZZY 1500 2 Allantoin 0.1 DL-Panthenol 0.3 Lee D. T.-2Na 0.02 Benzophenone-9 0.04 Hydroxyethyl cellulose 0.1 Sodium hyaruronate 8 Carboxyvinyl polymer 0.2 Triethanolamine 0.18 Octyldodecanol 0.3 Octyldodec-16 0.4 ethanol 6 Preservative, fragrance, pigment a very small amount Distilled water Balance Sum 100

Comparative Prescription Example  1 - Cream

Table 5 shows the prescription examples of the cream containing no Ganoderma lucidum extract. Comparative Prescription Example 1 contains the same ingredients as the cream of Prescription Example 2, except that it does not contain Ganoderma lucidum extract (Preparation Example 1).

ingredient Content (unit:% by weight) Pro-type glycerin monostearate 2 Cetearyl alcohol 2.2 Stearic acid 1.5 Wax One Polysorbate 60 1.5 Sorbitan stearate 0.6 Hardened vegetable oil One Squalane 3 Mineral oil 5 Trioctanoin 5 Dimethicone One Sodium magnesium silicate 0.1 glycerin 5 Betaine 3 Triethanolamine One Sodium hyaruronate 4 Preservative, fragrance, pigment a very small amount Distilled water Balance Sum 100

Experimental Example  2 - Cosmetic Cooling effect  Test

The cooling effect of the cosmetic composition containing the Ganoderma lucidum extract of the present invention was evaluated through practical use tests. The cream of Prescription Example 2 containing 3% by weight of Ganoderma lucidum extract and the cream of Comparative Prescription Example 1 were evaluated. The cream of Formulation Example 2 and the cream of Comparative Formulation Example 1 were applied to 30 men and women of 30 years old with two sizes of 3x3 cm on the front and back sides. After measuring the skin temperature before the test, the amount of the test substance and the solvent was applied at a rate of 18 袖 m / cm ² at intervals of 15 seconds to measure the skin temperature change over time. The measurement was performed using a Skin-Thermometer ST 500 (Courage Khazaka electronic GmbH, Germany). The statistical significance of the test formulations was verified by student t-test, and it was judged that there was a statistically significant difference at p <0.05. The results are shown in Table 6 and FIG. 2 below.

(Unit: ℃) 0 minutes 1 minute 2 minutes 3 minutes 4 minutes 5 minutes 6 minutes 7 minutes 8 minutes 9 minutes 10 minutes Prescription Example 2 31.69 29.81 29.25 30.08 30.38 30.71 31.01 31.14 31.14 31.11 31.22 Comparative Prescription Example 1 31.66 30.01 29.65 30.25 30.7 30.91 31.03 31.1 31.13 31.15 31.13

As can be seen from Table 6 and FIG. 2, the cosmetic composition containing the Ganoderma lucidum extract of the present invention (Formulation Example 2) showed a cooling effect as compared with the cosmetic composition containing no Ganoderma lucidum extract (Comparative Prescription Example 1) , And this effect is caused by the effect of near-infrared reflection of Ganoderma lucidum extract.

Claims (6)

Claims [1] A cosmetic composition for protecting near-infrared rays containing gingko mushroom extract,
Wherein the cosmetic composition has an effect of lowering skin temperature. The method according to claim 1,
Wherein the cosmetic composition reflects a wavelength in a heat or near infrared region. The method according to claim 1,
Wherein the cosmetic composition reflects a wavelength range of 800 to 1,300 nm. delete The method according to claim 1,
The gingko mushroom extract is characterized in that the gingko mushroom is extracted with an extraction solvent selected from the group consisting of water, an anhydrous or a lower alcohol having 1 to 4 carbon atoms, acetone, ethyl acetate, butyl acetate and 1,3-butylene glycol , Cosmetic composition. The method according to claim 1,
The cosmetic composition may be in the form of a solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation and spray &Lt; / RTI &gt;

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