KR101837104B1 - 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트 - Google Patents

수크랄페이트 합성 방법 및 이에 의한 수크랄페이트 Download PDF

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Publication number
KR101837104B1
KR101837104B1 KR1020170048497A KR20170048497A KR101837104B1 KR 101837104 B1 KR101837104 B1 KR 101837104B1 KR 1020170048497 A KR1020170048497 A KR 1020170048497A KR 20170048497 A KR20170048497 A KR 20170048497A KR 101837104 B1 KR101837104 B1 KR 101837104B1
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KR
South Korea
Prior art keywords
sucrose
sucralfate
polysulfate
solution
alkali metal
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KR1020170048497A
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English (en)
Korean (ko)
Inventor
김대익
이광수
신우철
김영찬
Original Assignee
한국프라임제약주식회사
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Priority to KR1020170048497A priority Critical patent/KR101837104B1/ko
Priority to CN201780092050.9A priority patent/CN110741012A/zh
Priority to PCT/KR2017/015790 priority patent/WO2018190493A1/fr
Application granted granted Critical
Publication of KR101837104B1 publication Critical patent/KR101837104B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1020170048497A 2017-04-14 2017-04-14 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트 KR101837104B1 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR1020170048497A KR101837104B1 (ko) 2017-04-14 2017-04-14 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트
CN201780092050.9A CN110741012A (zh) 2017-04-14 2017-12-31 硫糖铝的合成方法及其方法制得的硫糖铝
PCT/KR2017/015790 WO2018190493A1 (fr) 2017-04-14 2017-12-31 Procédé de synthèse de sucralfate et sucralfate ainsi obtenu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020170048497A KR101837104B1 (ko) 2017-04-14 2017-04-14 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트

Publications (1)

Publication Number Publication Date
KR101837104B1 true KR101837104B1 (ko) 2018-03-09

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KR1020170048497A KR101837104B1 (ko) 2017-04-14 2017-04-14 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트

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KR (1) KR101837104B1 (fr)
CN (1) CN110741012A (fr)
WO (1) WO2018190493A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431972B (zh) * 2018-11-20 2022-02-22 昆明积大制药股份有限公司 一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法
CN110981922A (zh) * 2019-12-17 2020-04-10 安徽赛诺制药有限公司 一种蔗糖八磺酸酯钾的制备方法
CN114437149A (zh) * 2020-11-03 2022-05-06 江苏开元药业有限公司 一种药用辅料盐的关键中间体钙盐的制备方法
CN115974938A (zh) * 2022-12-19 2023-04-18 辅必成（上海）医药科技有限公司 一种蔗糖七硫酸酯盐的合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100191189B1 (ko) * 1990-08-31 1999-06-15 나가야마 오사무 수크랄페이트 수성 현탁원액의 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3432489A (en) * 1965-11-05 1969-03-11 Chugai Pharmaceutical Co Ltd Disaccharide polysulfate aluminium compound and method
DK164199C (da) * 1986-05-16 1992-10-19 Chugai Pharmaceutical Co Ltd Sucralfatpraeparat til anvendelse paa oesophagus mucosa
US4990610A (en) * 1988-08-25 1991-02-05 Applied Analytical Industries, Inc. Method for preparing high potency sucralfate
KR100264547B1 (ko) * 1994-04-26 2000-12-01 나가야마 오사무 수크랄페이트의용융조립제제및그의제조방법
CN104490924A (zh) * 2014-12-05 2015-04-08 海南卫康制药(潜山)有限公司 一种硫糖铝组合物咀嚼片及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100191189B1 (ko) * 1990-08-31 1999-06-15 나가야마 오사무 수크랄페이트 수성 현탁원액의 제조방법

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Publication number Publication date
CN110741012A (zh) 2020-01-31
WO2018190493A1 (fr) 2018-10-18

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