KR101803113B1 - 방사성의약품 농도 측정 시스템 및 방법 - Google Patents

방사성의약품 농도 측정 시스템 및 방법 Download PDF

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KR101803113B1
KR101803113B1 KR1020127029294A KR20127029294A KR101803113B1 KR 101803113 B1 KR101803113 B1 KR 101803113B1 KR 1020127029294 A KR1020127029294 A KR 1020127029294A KR 20127029294 A KR20127029294 A KR 20127029294A KR 101803113 B1 KR101803113 B1 KR 101803113B1
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radiation
detector
radiopharmaceutical
demodulation
output
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KR20130040880A (ko
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마크 에이. 마비
래리 에이. 맥커찬
채드 이. 버튼
제임스 이. 디보스키
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바이엘 헬쓰케어 엘엘씨
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/167—Measuring radioactive content of objects, e.g. contamination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/20—Measuring radiation intensity with scintillation detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T7/00—Details of radiation-measuring instruments
    • G01T7/02—Collecting means for receiving or storing samples to be investigated and possibly directly transporting the samples to the measuring arrangement; particularly for investigating radioactive fluids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measurement Of Radiation (AREA)
  • Nuclear Medicine (AREA)
KR1020127029294A 2010-04-09 2011-04-11 방사성의약품 농도 측정 시스템 및 방법 Expired - Fee Related KR101803113B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32255510P 2010-04-09 2010-04-09
US61/322,555 2010-04-09
PCT/US2011/031949 WO2011127469A1 (en) 2010-04-09 2011-04-11 Radiopharmaceutical concentration measurement system and method

Publications (2)

Publication Number Publication Date
KR20130040880A KR20130040880A (ko) 2013-04-24
KR101803113B1 true KR101803113B1 (ko) 2017-12-28

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KR1020127029294A Expired - Fee Related KR101803113B1 (ko) 2010-04-09 2011-04-11 방사성의약품 농도 측정 시스템 및 방법

Country Status (7)

Country Link
US (1) US9715020B2 (enExample)
EP (1) EP2563409A4 (enExample)
JP (1) JP6078463B2 (enExample)
KR (1) KR101803113B1 (enExample)
CN (1) CN102834119B (enExample)
RU (1) RU2599866C2 (enExample)
WO (1) WO2011127469A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9436989B2 (en) 2011-06-03 2016-09-06 Bayer Healthcare Llc System and method for rapid quantitative dynamic molecular imaging scans
AU2012315757B9 (en) * 2011-09-30 2018-01-25 Ge Healthcare Limited Calibration and normalization systems and methods for radiopharmaceutical synthesizers
GB2497975B (en) * 2011-12-23 2016-05-11 Agilent Technologies Inc Adjustable aperture device with integral aperture holes
CA3174806A1 (en) 2012-09-05 2014-03-13 Jubilant Draximage, Inc. Rubidium elution system control
US10369276B2 (en) * 2013-11-25 2019-08-06 Bayer Healthcare Llc Accurately delivering partial doses of a drug post dilution using an injector
US20150309184A1 (en) * 2014-04-28 2015-10-29 Capintec, Inc. Communicating radioisotope dosage
RU2699307C2 (ru) 2014-12-16 2019-09-04 Конинклейке Филипс Н.В. Определение смещения базовой линии детектора фотонов
WO2018052447A1 (en) * 2016-09-19 2018-03-22 Siemens Medical Solutions Usa, Inc. Flexible application of cross-calibration for quantitative functional imaging
DK3516665T3 (da) 2016-09-20 2021-07-12 Bracco Diagnostics Inc Afskærmningsanordning til et radioisotopindgivelsessystem med flere strålingsdetektorer
US10245002B2 (en) * 2017-08-01 2019-04-02 Siemens Medical Solutions Usa, Inc. Isotope specific calibration of a dose calibrator for quantitative functional imaging
EP3679405B1 (en) * 2017-09-06 2023-07-12 The U.S.A. as represented by the Secretary, Department of Health and Human Services Micro-dose calibrator
SG11202009321SA (en) 2018-03-28 2020-10-29 Bracco Diagnostics Inc Systems and techniques for calibrating radioisotope delivery systems with a gamma detector
KR102733368B1 (ko) 2018-03-28 2024-11-21 브라코 다이어그노스틱스 아이엔씨. 방사성 동위 원소 생성기의 종료 수명의 조기 검출
CN109521457B (zh) * 2018-09-25 2022-10-21 中国辐射防护研究院 一种基于信息准则的γ辐射源项划分方法及系统
CN109669204B (zh) 2019-01-08 2019-09-06 山西医科大学 一种czt半导体活度计以及活度测量装置
US11493662B2 (en) 2020-05-28 2022-11-08 Halliburton Energy Services, Inc. Determining density of multiple layers using gamma spectroscopy
CN111999763B (zh) * 2020-08-26 2022-12-30 山西医科大学 容纳装置及活度检测工位、活度检测方法
CN113484896B (zh) * 2021-07-01 2024-05-10 成都纽瑞特医疗科技股份有限公司 一种放射性物质检测装置
CN113945961A (zh) * 2021-10-21 2022-01-18 北京森科医药有限公司 药物标记设备和方法
FR3129000B1 (fr) * 2021-11-09 2025-01-10 Commissariat Energie Atomique Détecteur de rayonnement ionisant comportant un modulateur pour moduler l’intensité du rayonnement
CN118279423B (zh) * 2024-03-26 2024-10-29 合肥拓康科技有限公司 事件的符合事件个数校准方法、装置及电子设备
CN119361071B (zh) * 2024-12-25 2025-07-29 北京科技大学 一种用于成像注射前分析的放射性药物用量控制系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996035131A1 (en) * 1995-05-05 1996-11-07 Capintec, Inc. Non-invasive radio nuclide detection meter
US20040054248A1 (en) * 2000-08-21 2004-03-18 Yoav Kimchy Radioactive emission detector equipped with a position tracking system
US20040260143A1 (en) 2001-06-29 2004-12-23 Reilly David M. Delivery methods, systems and components for use with hazardous pharmaceutical substances

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307713A (en) * 1980-02-13 1981-12-29 Thomas Jefferson University Syringe shields and methods for using same
US4409488A (en) 1981-03-06 1983-10-11 King Russell W Radioactive material dose computer
US4853546A (en) 1986-09-16 1989-08-01 Ube Industries, Ltd. Automatic radioisotope filling apparatus
JPH0648319B2 (ja) * 1986-11-12 1994-06-22 宇部興産株式会社 ラジオアイソトープ自動分注装置及び自動分注方法
JPS63143354U (enExample) 1987-03-11 1988-09-21
JPH065297B2 (ja) * 1987-10-09 1994-01-19 浜松ホトニクス株式会社 核種弁別可能な線量計測装置
JPH0611003Y2 (ja) 1988-05-09 1994-03-23 日本メジフィジックス株式会社 放射性物質注射装置
JP3040326B2 (ja) * 1995-04-17 2000-05-15 アロカ株式会社 放射線測定装置
DE59600583D1 (de) 1995-05-03 1998-10-22 Oce Printing Systems Gmbh Reinigungsvorrichtung für die fotoleitertrommel eines druck- oder kopiergerätes
JPH1039033A (ja) * 1996-07-26 1998-02-13 Toshiba Corp 核種分析装置
US6362472B1 (en) * 1999-10-22 2002-03-26 Ethicon Endo-Surgery, Inc. Method for calibrating a radiation detection system
US7373197B2 (en) * 2000-03-03 2008-05-13 Intramedical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
WO2004004787A2 (en) 2002-07-05 2004-01-15 Universite Libre De Bruxelles - Hopital Erasme Method and device for dispensing individual doses of a radiopharmaceutical solution
GB0308407D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Method of obtaining 68 GA
EP1616587A1 (en) 2004-07-16 2006-01-18 Universität Zürich Method and device for accurate dispensing of radioactivity
JP4519699B2 (ja) 2005-04-07 2010-08-04 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー Ｘ線ｃｔ装置
RU53880U1 (ru) * 2005-08-26 2006-06-10 Государственное научное учреждение "Объединенный институт проблем информатики Национальной академии наук Беларуси" ("ОИПИ НАН Беларуси") Устройство для регистрации ренографических исследований
FR2906475B1 (fr) * 2006-09-29 2009-01-09 Lemer Prot Anti X Par Abrevati Unite medicale pour le prelevement,le calibrage,la dilution et/ou l'injection d'un produit radioactif injectable
US9056164B2 (en) 2007-01-01 2015-06-16 Bayer Medical Care Inc. Radiopharmaceutical administration methods, fluid delivery systems and components thereof
US20080166292A1 (en) * 2007-01-01 2008-07-10 Medrad, Inc. Pharmaceutical Dosing Method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996035131A1 (en) * 1995-05-05 1996-11-07 Capintec, Inc. Non-invasive radio nuclide detection meter
US20040054248A1 (en) * 2000-08-21 2004-03-18 Yoav Kimchy Radioactive emission detector equipped with a position tracking system
US20040260143A1 (en) 2001-06-29 2004-12-23 Reilly David M. Delivery methods, systems and components for use with hazardous pharmaceutical substances

Also Published As

Publication number Publication date
RU2599866C2 (ru) 2016-10-20
EP2563409A4 (en) 2016-10-26
JP6078463B2 (ja) 2017-02-08
RU2012147588A (ru) 2014-05-20
WO2011127469A1 (en) 2011-10-13
US9715020B2 (en) 2017-07-25
CN102834119A (zh) 2012-12-19
JP2013524245A (ja) 2013-06-17
EP2563409A1 (en) 2013-03-06
KR20130040880A (ko) 2013-04-24
CN102834119B (zh) 2015-02-04
US20130124103A1 (en) 2013-05-16

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