KR101787434B1 - 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법 - Google Patents

이미노슈가 및 아레나바이러스성 감염을 치료하는 방법 Download PDF

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Publication number
KR101787434B1
KR101787434B1 KR1020117021910A KR20117021910A KR101787434B1 KR 101787434 B1 KR101787434 B1 KR 101787434B1 KR 1020117021910 A KR1020117021910 A KR 1020117021910A KR 20117021910 A KR20117021910 A KR 20117021910A KR 101787434 B1 KR101787434 B1 KR 101787434B1
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virus
delete delete
pharmaceutical composition
dnj
hemorrhagic fever
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KR20120042718A (ko
Inventor
얼반 람스테트
브렌난 클로세
니콜 지츠만
레이몬드 에이. 드웩
테리 디. 버터스
Original Assignee
유나이티드 세러퓨틱스 코오포레이션
더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드
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Application filed by 유나이티드 세러퓨틱스 코오포레이션, 더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드 filed Critical 유나이티드 세러퓨틱스 코오포레이션
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020117021910A 2009-02-24 2010-02-22 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법 Expired - Fee Related KR101787434B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20239109P 2009-02-24 2009-02-24
US61/202,391 2009-02-24
US27225109P 2009-09-04 2009-09-04
US61/272,251 2009-09-04
PCT/US2010/024914 WO2010099064A1 (en) 2009-02-24 2010-02-22 Iminosugars and methods of treating arenaviral infections

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020177029196A Division KR20170117614A (ko) 2009-02-24 2010-02-22 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법

Publications (2)

Publication Number Publication Date
KR20120042718A KR20120042718A (ko) 2012-05-03
KR101787434B1 true KR101787434B1 (ko) 2017-11-15

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KR1020117021910A Expired - Fee Related KR101787434B1 (ko) 2009-02-24 2010-02-22 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법
KR1020177029196A Ceased KR20170117614A (ko) 2009-02-24 2010-02-22 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법

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KR1020177029196A Ceased KR20170117614A (ko) 2009-02-24 2010-02-22 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법

Country Status (8)

Country Link
US (1) US20100222384A1 (enExample)
EP (1) EP2400843B1 (enExample)
JP (1) JP5951996B2 (enExample)
KR (2) KR101787434B1 (enExample)
CN (1) CN102625660B (enExample)
CA (1) CA2753194A1 (enExample)
ES (1) ES2562635T3 (enExample)
WO (1) WO2010099064A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2398321B1 (en) 2009-02-23 2015-11-25 United Therapeutics Corporation Iminosugars and methods of treating viral diseases
WO2013184780A1 (en) 2012-06-06 2013-12-12 Unither Virology, Llc Novel iminosugars and their applications
CN102775384B (zh) * 2012-07-27 2015-05-27 中国科学院化学研究所 小钩树碱i和j类似物及其制备方法与应用
US20160075651A1 (en) * 2013-05-02 2016-03-17 Unither Virology, Llc Glycolipid inhibition using iminosugars
WO2015039010A2 (en) 2013-09-16 2015-03-19 Unither Virology, Llc Deoxynojirimycin derivatives and methods of their using
IT202000008917A1 (it) * 2020-04-24 2021-10-24 Biovalley Invest Partner S R L Composizioni antivirali
KR20250160378A (ko) 2024-05-06 2025-11-13 문제정 가구재용 서랍 조립시스템

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US20070275998A1 (en) 2006-05-24 2007-11-29 Butters Terry D Deoxynojirimycin and d-arabinitol analogs and methods of using
WO2010027996A1 (en) 2008-09-02 2010-03-11 Institute For Hepatitis And Virus Research Novel imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity

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WO2006077427A2 (en) * 2005-01-21 2006-07-27 Mnl Pharma Limited Antiviral drug combinations
US20070275998A1 (en) 2006-05-24 2007-11-29 Butters Terry D Deoxynojirimycin and d-arabinitol analogs and methods of using
WO2010027996A1 (en) 2008-09-02 2010-03-11 Institute For Hepatitis And Virus Research Novel imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity

Also Published As

Publication number Publication date
JP5951996B2 (ja) 2016-07-13
JP2012518648A (ja) 2012-08-16
HK1165675A1 (en) 2012-10-12
US20100222384A1 (en) 2010-09-02
CN102625660B (zh) 2015-03-11
CA2753194A1 (en) 2010-09-02
EP2400843A4 (en) 2012-01-04
EP2400843A1 (en) 2012-01-04
EP2400843B1 (en) 2015-11-11
CN102625660A (zh) 2012-08-01
KR20170117614A (ko) 2017-10-23
ES2562635T3 (es) 2016-03-07
KR20120042718A (ko) 2012-05-03
WO2010099064A1 (en) 2010-09-02

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