CN102625660B - 亚氨基糖以及治疗沙粒病毒感染的方法 - Google Patents
亚氨基糖以及治疗沙粒病毒感染的方法 Download PDFInfo
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- CN102625660B CN102625660B CN201080017592.8A CN201080017592A CN102625660B CN 102625660 B CN102625660 B CN 102625660B CN 201080017592 A CN201080017592 A CN 201080017592A CN 102625660 B CN102625660 B CN 102625660B
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- 239000006195 ophthalmic dosage form Substances 0.000 description 1
- 239000008184 oral solid dosage form Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 229940075930 picrate Drugs 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
- IUGYQRQAERSCNH-UHFFFAOYSA-N pivalic acid Chemical class CC(C)(C)C(O)=O IUGYQRQAERSCNH-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
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- 239000006208 topical dosage form Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US20239109P | 2009-02-24 | 2009-02-24 | |
| US61/202,391 | 2009-02-24 | ||
| US27225109P | 2009-09-04 | 2009-09-04 | |
| US61/272,251 | 2009-09-04 | ||
| PCT/US2010/024914 WO2010099064A1 (en) | 2009-02-24 | 2010-02-22 | Iminosugars and methods of treating arenaviral infections |
Publications (2)
| Publication Number | Publication Date |
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| CN102625660A CN102625660A (zh) | 2012-08-01 |
| CN102625660B true CN102625660B (zh) | 2015-03-11 |
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| EP (1) | EP2400843B1 (enExample) |
| JP (1) | JP5951996B2 (enExample) |
| KR (2) | KR20170117614A (enExample) |
| CN (1) | CN102625660B (enExample) |
| CA (1) | CA2753194A1 (enExample) |
| ES (1) | ES2562635T3 (enExample) |
| WO (1) | WO2010099064A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2398321B1 (en) | 2009-02-23 | 2015-11-25 | United Therapeutics Corporation | Iminosugars and methods of treating viral diseases |
| JP2015518896A (ja) | 2012-06-06 | 2015-07-06 | ユニザー ヴィロロジー，エルエルシー | 新規イミノ糖およびそれらの用途 |
| CN102775384B (zh) * | 2012-07-27 | 2015-05-27 | 中国科学院化学研究所 | 小钩树碱i和j类似物及其制备方法与应用 |
| US20160075651A1 (en) * | 2013-05-02 | 2016-03-17 | Unither Virology, Llc | Glycolipid inhibition using iminosugars |
| EP3046558B1 (en) | 2013-09-16 | 2019-08-14 | Emergent Virology LLC | Deoxynojirimycin derivatives and methods of their using |
| IT202000008917A1 (it) * | 2020-04-24 | 2021-10-24 | Biovalley Invest Partner S R L | Composizioni antivirali |
| KR20250160378A (ko) | 2024-05-06 | 2025-11-13 | 문제정 | 가구재용 서랍 조립시스템 |
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- 2010-02-22 CA CA2753194A patent/CA2753194A1/en not_active Abandoned
- 2010-02-22 EP EP10746681.5A patent/EP2400843B1/en not_active Not-in-force
- 2010-02-22 JP JP2011551272A patent/JP5951996B2/ja not_active Expired - Fee Related
- 2010-02-22 KR KR1020177029196A patent/KR20170117614A/ko not_active Ceased
- 2010-02-22 ES ES10746681.5T patent/ES2562635T3/es active Active
- 2010-02-22 CN CN201080017592.8A patent/CN102625660B/zh not_active Expired - Fee Related
- 2010-02-22 WO PCT/US2010/024914 patent/WO2010099064A1/en not_active Ceased
- 2010-02-22 US US12/656,993 patent/US20100222384A1/en not_active Abandoned
- 2010-02-22 KR KR1020117021910A patent/KR101787434B1/ko not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102625660A (zh) | 2012-08-01 |
| CA2753194A1 (en) | 2010-09-02 |
| JP2012518648A (ja) | 2012-08-16 |
| WO2010099064A1 (en) | 2010-09-02 |
| EP2400843A1 (en) | 2012-01-04 |
| KR101787434B1 (ko) | 2017-11-15 |
| US20100222384A1 (en) | 2010-09-02 |
| ES2562635T3 (es) | 2016-03-07 |
| EP2400843A4 (en) | 2012-01-04 |
| KR20120042718A (ko) | 2012-05-03 |
| EP2400843B1 (en) | 2015-11-11 |
| HK1165675A1 (en) | 2012-10-12 |
| KR20170117614A (ko) | 2017-10-23 |
| JP5951996B2 (ja) | 2016-07-13 |
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