KR101612563B1 - 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 - Google Patents

도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 Download PDF

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KR101612563B1
KR101612563B1 KR1020107004638A KR20107004638A KR101612563B1 KR 101612563 B1 KR101612563 B1 KR 101612563B1 KR 1020107004638 A KR1020107004638 A KR 1020107004638A KR 20107004638 A KR20107004638 A KR 20107004638A KR 101612563 B1 KR101612563 B1 KR 101612563B1
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escitalopram
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KR20100059830A (ko
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니카 애드함
게리 사모리스키
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리히터 게데온 닐트.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
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    • AHUMAN NECESSITIES
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020107004638A 2007-08-03 2008-08-04 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법 Active KR101612563B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95369407P 2007-08-03 2007-08-03
US60/953,694 2007-08-03

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KR20100059830A KR20100059830A (ko) 2010-06-04
KR101612563B1 true KR101612563B1 (ko) 2016-04-14

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KR1020107004638A Active KR101612563B1 (ko) 2007-08-03 2008-08-04 도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법

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US (3) US20090036468A1 (cg-RX-API-DMAC10.html)
EP (1) EP2185155B1 (cg-RX-API-DMAC10.html)
JP (1) JP5460594B2 (cg-RX-API-DMAC10.html)
KR (1) KR101612563B1 (cg-RX-API-DMAC10.html)
CN (1) CN101815519B (cg-RX-API-DMAC10.html)
AU (1) AU2008283989B2 (cg-RX-API-DMAC10.html)
CA (1) CA2695519A1 (cg-RX-API-DMAC10.html)
CY (1) CY1119828T1 (cg-RX-API-DMAC10.html)
DK (1) DK2185155T3 (cg-RX-API-DMAC10.html)
EA (1) EA018064B1 (cg-RX-API-DMAC10.html)
ES (1) ES2653852T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20171908T1 (cg-RX-API-DMAC10.html)
HU (1) HUE036004T2 (cg-RX-API-DMAC10.html)
LT (1) LT2185155T (cg-RX-API-DMAC10.html)
MY (1) MY157192A (cg-RX-API-DMAC10.html)
NO (1) NO2185155T3 (cg-RX-API-DMAC10.html)
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PT (1) PT2185155T (cg-RX-API-DMAC10.html)
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MY156288A (en) 2008-07-16 2016-01-29 Richter Gedeon Nyrt Pharmaceutical formulations containing dopamine receptor ligands.
WO2011060363A2 (en) * 2009-11-16 2011-05-19 Auspex Pharmaceuticals, Inc. Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
MX390264B (es) * 2010-06-18 2025-03-20 Takeda Pharmaceuticals Co Antagonistas d2, metodos de sintesis y metodos de uso.
WO2014031162A1 (en) 2012-08-20 2014-02-27 Forest Laboratories Holdings Limited Crystalline form of carbamoyl-cyclohexane derivatives
US11274087B2 (en) 2016-07-08 2022-03-15 Richter Gedeon Nyrt. Industrial process for the preparation of cariprazine
HUP1700253A1 (hu) * 2017-06-13 2019-01-28 Richter Gedeon Nyrt Szilárd orális gyógyszerkészítmények
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US11547707B2 (en) 2019-04-10 2023-01-10 Richter Gedeon Nyrt. Carbamoyl cyclohexane derivatives for treating autism spectrum disorder
HU231500B1 (hu) * 2019-04-10 2024-04-28 Richter Gedeon Nyrt Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére
US12433904B2 (en) 2019-04-17 2025-10-07 Compass Pathfinder Limited Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin
GEAP202416526A (en) * 2021-10-28 2024-09-25 Richter Gedeon Nyrt Treatment of major depressive disorder
CA3240774A1 (en) * 2021-12-13 2023-06-22 Compass Pathfinder Limited Psilocybin and an adjunctive serotonin reuptake inhibitor for use in the treatment of treatment-resistant depression
CN119136804A (zh) * 2022-03-17 2024-12-13 Mapi医药公司 包含卡利拉嗪或其盐的储库系统

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GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
ZA977967B (en) * 1996-09-23 1999-03-04 Lilly Co Eli Combination therapy for treatment of psychoses
US6960577B2 (en) * 1998-05-22 2005-11-01 Eli Lilly And Company Combination therapy for treatment of refractory depression
US6556540B1 (en) * 1998-05-29 2003-04-29 Paradyne Corporation System and method for non-intrusive measurement of service quality in a communications network
HK1043129B (zh) * 1999-10-25 2004-10-21 H‧隆德贝克有限公司 西酞普蘭的製備方法
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
JP2004527551A (ja) * 2001-05-01 2004-09-09 ハー・ルンドベック・アクチエゼルスカベット エナンチオ純粋なエスシタロプラムの使用方法
WO2003086393A1 (en) * 2002-04-12 2003-10-23 Sepracor, Inc. 3-aza- and 1,4-diaza-bicyclo[4.3.0]nonanes, and methods of use thereof
JP2005533069A (ja) * 2002-06-20 2005-11-04 ハー・ルンドベック・アクチエゼルスカベット セロトニン再取り込み阻害剤を使用する組み合わせ治療法
HU227534B1 (en) * 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
KR20060072127A (ko) * 2003-09-04 2006-06-27 하. 룬트벡 아크티에 셀스카브 세로토닌 재흡수 억제제 및 록사핀의 조합
HUP0500170A3 (en) * 2005-02-03 2007-11-28 Richter Gedeon Nyrt Piperazine derivatives, process for producing them and pharmaceutical compositions containing them
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HU230748B1 (hu) * 2007-05-11 2018-02-28 Richter Gedeon Nyrt Új piperazin só és előállítási eljárása

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MY157192A (en) 2016-05-13
EA201000280A1 (ru) 2010-08-30
CA2695519A1 (en) 2009-02-12
HRP20171908T1 (hr) 2018-01-26
HK1144784A1 (en) 2011-03-11
AU2008283989A1 (en) 2009-02-12
US20110015208A1 (en) 2011-01-20
SI2185155T1 (en) 2018-02-28
US20090036468A1 (en) 2009-02-05
CY1119828T1 (el) 2018-06-27
KR20100059830A (ko) 2010-06-04
EP2185155A4 (en) 2012-04-25
NO2185155T3 (cg-RX-API-DMAC10.html) 2018-03-03
ES2653852T3 (es) 2018-02-09
EA018064B1 (ru) 2013-05-30
EP2185155B1 (en) 2017-10-04
LT2185155T (lt) 2017-12-11
WO2009020897A1 (en) 2009-02-12
JP2010535790A (ja) 2010-11-25
PT2185155T (pt) 2018-01-04
PL2185155T3 (pl) 2018-03-30
DK2185155T3 (en) 2018-01-02
HUE036004T2 (hu) 2018-06-28
JP5460594B2 (ja) 2014-04-02
US20120028991A1 (en) 2012-02-02
CN101815519A (zh) 2010-08-25
AU2008283989B2 (en) 2013-12-05
EP2185155A1 (en) 2010-05-19
CN101815519B (zh) 2013-08-21

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