KR101563757B1 - 복부 대동맥류 치료를 위한 트리아졸로[4,5-d]피리미딘 화합물 - Google Patents

복부 대동맥류 치료를 위한 트리아졸로[4,5-d]피리미딘 화합물 Download PDF

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KR101563757B1
KR101563757B1 KR1020107013193A KR20107013193A KR101563757B1 KR 101563757 B1 KR101563757 B1 KR 101563757B1 KR 1020107013193 A KR1020107013193 A KR 1020107013193A KR 20107013193 A KR20107013193 A KR 20107013193A KR 101563757 B1 KR101563757 B1 KR 101563757B1
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compound
treatment
wall
thrombus
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KR20100099175A (ko
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장-밥티스트 미셀
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아스트라제네카 아베
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020107013193A 2007-12-03 2008-12-02 복부 대동맥류 치료를 위한 트리아졸로[4,5-d]피리미딘 화합물 Active KR101563757B1 (ko)

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EP07301616.4 2007-12-03
EP07301616 2007-12-03

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KR20100099175A KR20100099175A (ko) 2010-09-10
KR101563757B1 true KR101563757B1 (ko) 2015-10-27

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KR1020107013193A Active KR101563757B1 (ko) 2007-12-03 2008-12-02 복부 대동맥류 치료를 위한 트리아졸로[4,5-d]피리미딘 화합물

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US (2) US20100298350A1 (https=)
EP (1) EP2229172B1 (https=)
JP (1) JP5701060B2 (https=)
KR (1) KR101563757B1 (https=)
CN (2) CN103919781A (https=)
AU (1) AU2008331984B2 (https=)
BR (1) BRPI0819458A2 (https=)
CA (1) CA2707488C (https=)
CY (1) CY1115760T1 (https=)
DK (1) DK2229172T3 (https=)
EA (1) EA201000928A1 (https=)
ES (1) ES2522317T3 (https=)
HR (1) HRP20141081T1 (https=)
IL (1) IL205613A (https=)
MX (1) MX2010006101A (https=)
MY (1) MY159656A (https=)
NZ (1) NZ585513A (https=)
PL (1) PL2229172T3 (https=)
PT (1) PT2229172E (https=)
RS (1) RS53635B1 (https=)
SI (1) SI2229172T1 (https=)
UA (1) UA100864C2 (https=)
WO (1) WO2009072967A1 (https=)
ZA (1) ZA201003599B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102653539B (zh) * 2011-03-01 2014-09-17 秦引林 一种抗血小板聚集化合物及其药物组合
CN102924457A (zh) * 2011-08-12 2013-02-13 上海恒瑞医药有限公司 三唑并嘧啶类衍生物、其制备方法及其用途
WO2013033178A1 (en) 2011-08-30 2013-03-07 University Of Utah Research Foundation Methods and compositions for treating nephrogenic diabetes insipidus

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000034283A1 (en) 1998-12-04 2000-06-15 Astrazeneca Ab Novel triazolo(4,5-d)pyrimidine compounds
WO2001092262A1 (en) 2000-06-02 2001-12-06 Astrazeneca Ab New crystalline and amorphous form of a triazolo(4,5-d)pyrimidine compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199800019T1 (xx) * 1995-07-11 1998-05-21 Astra Pharmaceuticals Limited Trombosit topaklanmas�n� �nleyici yeni maddeler.
AR017014A1 (es) * 1997-07-22 2001-08-22 Astrazeneca Ab Compuestos de triazolo [4,5-d]pirimidina, composiciones farmaceuticas, uso de los mismos para preparar medicamentos y procesos para la preparacionde dichos compuestos
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
WO2009007675A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a p2 gamma 12 antagonist

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000034283A1 (en) 1998-12-04 2000-06-15 Astrazeneca Ab Novel triazolo(4,5-d)pyrimidine compounds
US20070265282A1 (en) 1998-12-04 2007-11-15 Astrazeneca Ab Novel compounds
WO2001092262A1 (en) 2000-06-02 2001-12-06 Astrazeneca Ab New crystalline and amorphous form of a triazolo(4,5-d)pyrimidine compound

Also Published As

Publication number Publication date
EP2229172A4 (en) 2012-12-26
IL205613A0 (en) 2010-11-30
MX2010006101A (es) 2010-10-04
BRPI0819458A2 (pt) 2015-05-05
JP5701060B2 (ja) 2015-04-15
NZ585513A (en) 2012-07-27
EA201000928A1 (ru) 2010-12-30
ES2522317T3 (es) 2014-11-14
CY1115760T1 (el) 2017-01-25
CN101883565A (zh) 2010-11-10
CA2707488A1 (en) 2009-06-11
PT2229172E (pt) 2014-11-03
US20100298350A1 (en) 2010-11-25
RS53635B1 (sr) 2015-04-30
DK2229172T3 (da) 2014-11-10
EP2229172A1 (en) 2010-09-22
JP2011505417A (ja) 2011-02-24
CN103919781A (zh) 2014-07-16
HK1148195A1 (en) 2011-09-02
AU2008331984B2 (en) 2012-08-16
US20150272955A1 (en) 2015-10-01
SI2229172T1 (sl) 2014-12-31
AU2008331984A1 (en) 2009-06-11
PL2229172T3 (pl) 2015-01-30
MY159656A (en) 2017-01-13
IL205613A (en) 2015-04-30
HRP20141081T1 (hr) 2015-01-02
WO2009072967A1 (en) 2009-06-11
EP2229172B1 (en) 2014-09-10
ZA201003599B (en) 2012-10-31
KR20100099175A (ko) 2010-09-10
UA100864C2 (uk) 2013-02-11
CA2707488C (en) 2015-07-28

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