KR101506928B1 - 보호된 분석대상물의 제어 방출에 의한 시험 요소에서 효소의 분해 검출 - Google Patents

보호된 분석대상물의 제어 방출에 의한 시험 요소에서 효소의 분해 검출 Download PDF

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KR101506928B1
KR101506928B1 KR1020127015674A KR20127015674A KR101506928B1 KR 101506928 B1 KR101506928 B1 KR 101506928B1 KR 1020127015674 A KR1020127015674 A KR 1020127015674A KR 20127015674 A KR20127015674 A KR 20127015674A KR 101506928 B1 KR101506928 B1 KR 101506928B1
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analyte
diagnostic unit
layer
marker
reagent
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KR20120102084A (ko
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카리나 호른
디터 하인들
한스-페터 하르
넬리 슈타인케
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에프. 호프만-라 로슈 아게
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
KR1020127015674A 2009-12-16 2010-12-15 보호된 분석대상물의 제어 방출에 의한 시험 요소에서 효소의 분해 검출 Active KR101506928B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09179500 2009-12-16
EP09179500.5 2009-12-16
PCT/EP2010/069760 WO2011073258A1 (de) 2009-12-16 2010-12-15 Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt

Publications (2)

Publication Number Publication Date
KR20120102084A KR20120102084A (ko) 2012-09-17
KR101506928B1 true KR101506928B1 (ko) 2015-03-30

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KR1020127015674A Active KR101506928B1 (ko) 2009-12-16 2010-12-15 보호된 분석대상물의 제어 방출에 의한 시험 요소에서 효소의 분해 검출

Country Status (10)

Country Link
US (1) US10260085B2 (cg-RX-API-DMAC7.html)
EP (1) EP2513648B1 (cg-RX-API-DMAC7.html)
JP (1) JP5777633B2 (cg-RX-API-DMAC7.html)
KR (1) KR101506928B1 (cg-RX-API-DMAC7.html)
CN (1) CN102741694B (cg-RX-API-DMAC7.html)
CA (1) CA2782943C (cg-RX-API-DMAC7.html)
ES (1) ES2544984T3 (cg-RX-API-DMAC7.html)
MX (1) MX2012006706A (cg-RX-API-DMAC7.html)
PL (1) PL2513648T3 (cg-RX-API-DMAC7.html)
WO (1) WO2011073258A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
KR101669739B1 (ko) * 2011-11-14 2016-10-27 에프. 호프만-라 로슈 아게 샘플에서 적어도 하나의 분석물을 검출하기 위한 분석 장치
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
FR3086951B1 (fr) * 2018-10-05 2021-02-26 Redberry Methode et dispositif pour la detection d'au moins un microorganisme selon sa cinetique de marquage, et support de detection
US20220338768A1 (en) * 2021-04-09 2022-10-27 Medtronic Minimed, Inc. Hexamethyldisiloxane membranes for analyte sensors

Citations (2)

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US20030211006A1 (en) 2002-05-10 2003-11-13 Suyue Qian Multilayer reagent test strips that include at least one fluid flow control layer and methods for using the same
WO2006065900A1 (en) 2004-12-13 2006-06-22 Bayer Healthcare Llc Size self-limiting compositions and test devices for measuring analytes in biological fluids

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CA1054034A (en) * 1975-06-20 1979-05-08 Barbara J. Bruschi Multilayer analytical element
US4649121A (en) * 1985-02-26 1987-03-10 Miles Laboratories, Inc. Viability test device
US4689309A (en) * 1985-09-30 1987-08-25 Miles Laboratories, Inc. Test device, method of manufacturing same and method of determining a component in a sample
DE29614429U1 (de) * 1996-08-09 1996-10-24 Merete GmbH, 10719 Berlin Teststreifen zur Untersuchung einer körpereigenen Flüssigkeit
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
US20040126831A1 (en) * 2002-12-31 2004-07-01 Medtronic Minimed, Inc. Functionalization of immobilized proteins
MXPA06001719A (es) 2003-08-11 2006-05-19 Codexis Inc Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados.
GB0403369D0 (en) 2004-02-16 2004-03-17 Pa Consulting Services Devices and methods for testing analytes
WO2005084530A2 (en) 2004-03-06 2005-09-15 F. Hoffmann-La Roche Ag Body fluid sampling device
PL1739432T3 (pl) 2005-06-29 2012-03-30 Hoffmann La Roche System analityczny z taśmą testującą
DE102005035461A1 (de) 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
JP4786451B2 (ja) * 2005-07-28 2011-10-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Ｎａｄ／ｎａｄｈの安定化
US20070196899A1 (en) 2005-11-29 2007-08-23 Sony Corporation Mutant protein having diaphorase activity
CN101058824A (zh) * 2006-04-21 2007-10-24 北京化工大学 固定化酶生物催化剂及其制备方法和应用
WO2007127981A2 (en) * 2006-04-28 2007-11-08 University Of Rochester Analyte-releasing beads and use thereof in quantitative elispot or fluorispot assay
KR100690930B1 (ko) * 2006-05-03 2007-03-09 한국기계연구원 깊은 제거를 이용하여 원하는 패턴 두께 혹은 높은종횡비를 가지는 고해상도 패턴 형성 방법
EP1965198A1 (en) * 2007-02-27 2008-09-03 F. Hoffmann-La Roche AG Dry optical-chemical carbon-dioxide sensor
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CN101329264A (zh) * 2007-06-21 2008-12-24 苏州艾杰生物科技有限公司 蔗糖酶诊断/测定试剂盒及蔗糖酶活性浓度测定方法
EP2093284A1 (de) * 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP2333544A1 (de) * 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030211006A1 (en) 2002-05-10 2003-11-13 Suyue Qian Multilayer reagent test strips that include at least one fluid flow control layer and methods for using the same
WO2006065900A1 (en) 2004-12-13 2006-06-22 Bayer Healthcare Llc Size self-limiting compositions and test devices for measuring analytes in biological fluids

Also Published As

Publication number Publication date
ES2544984T3 (es) 2015-09-07
US10260085B2 (en) 2019-04-16
US20130052674A1 (en) 2013-02-28
JP2013524770A (ja) 2013-06-20
CN102741694A (zh) 2012-10-17
KR20120102084A (ko) 2012-09-17
EP2513648B1 (de) 2015-05-27
HK1177501A1 (en) 2013-08-23
WO2011073258A1 (de) 2011-06-23
CN102741694B (zh) 2014-12-24
CA2782943C (en) 2014-09-09
JP5777633B2 (ja) 2015-09-09
MX2012006706A (es) 2012-07-03
PL2513648T3 (pl) 2015-11-30
CA2782943A1 (en) 2011-06-23
EP2513648A1 (de) 2012-10-24

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