CA2782943C - Detecting the decomposition of enzymes in a test element by means of controlled release of a protected analyte - Google Patents

Detecting the decomposition of enzymes in a test element by means of controlled release of a protected analyte Download PDF

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Publication number
CA2782943C
CA2782943C CA2782943A CA2782943A CA2782943C CA 2782943 C CA2782943 C CA 2782943C CA 2782943 A CA2782943 A CA 2782943A CA 2782943 A CA2782943 A CA 2782943A CA 2782943 C CA2782943 C CA 2782943C
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CA
Canada
Prior art keywords
analyte
diagnostic element
element according
indicator
diagnostic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2782943A
Other languages
English (en)
French (fr)
Other versions
CA2782943A1 (en
Inventor
Carina Horn
Dieter Heindl
Hans-Peter Haar
Nelli Steinke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2782943A1 publication Critical patent/CA2782943A1/en
Application granted granted Critical
Publication of CA2782943C publication Critical patent/CA2782943C/en
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2782943A 2009-12-16 2010-12-15 Detecting the decomposition of enzymes in a test element by means of controlled release of a protected analyte Active CA2782943C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09179500 2009-12-16
EP09179500.5 2009-12-16
PCT/EP2010/069760 WO2011073258A1 (de) 2009-12-16 2010-12-15 Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt

Publications (2)

Publication Number Publication Date
CA2782943A1 CA2782943A1 (en) 2011-06-23
CA2782943C true CA2782943C (en) 2014-09-09

Family

ID=42015323

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2782943A Active CA2782943C (en) 2009-12-16 2010-12-15 Detecting the decomposition of enzymes in a test element by means of controlled release of a protected analyte

Country Status (10)

Country Link
US (1) US10260085B2 (cg-RX-API-DMAC7.html)
EP (1) EP2513648B1 (cg-RX-API-DMAC7.html)
JP (1) JP5777633B2 (cg-RX-API-DMAC7.html)
KR (1) KR101506928B1 (cg-RX-API-DMAC7.html)
CN (1) CN102741694B (cg-RX-API-DMAC7.html)
CA (1) CA2782943C (cg-RX-API-DMAC7.html)
ES (1) ES2544984T3 (cg-RX-API-DMAC7.html)
MX (1) MX2012006706A (cg-RX-API-DMAC7.html)
PL (1) PL2513648T3 (cg-RX-API-DMAC7.html)
WO (1) WO2011073258A1 (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
KR101669739B1 (ko) * 2011-11-14 2016-10-27 에프. 호프만-라 로슈 아게 샘플에서 적어도 하나의 분석물을 검출하기 위한 분석 장치
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
FR3086951B1 (fr) * 2018-10-05 2021-02-26 Redberry Methode et dispositif pour la detection d'au moins un microorganisme selon sa cinetique de marquage, et support de detection
US20220338768A1 (en) * 2021-04-09 2022-10-27 Medtronic Minimed, Inc. Hexamethyldisiloxane membranes for analyte sensors

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DE29614429U1 (de) * 1996-08-09 1996-10-24 Merete GmbH, 10719 Berlin Teststreifen zur Untersuchung einer körpereigenen Flüssigkeit
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
US20030211006A1 (en) 2002-05-10 2003-11-13 Suyue Qian Multilayer reagent test strips that include at least one fluid flow control layer and methods for using the same
US20040126831A1 (en) * 2002-12-31 2004-07-01 Medtronic Minimed, Inc. Functionalization of immobilized proteins
MXPA06001719A (es) 2003-08-11 2006-05-19 Codexis Inc Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados.
GB0403369D0 (en) 2004-02-16 2004-03-17 Pa Consulting Services Devices and methods for testing analytes
WO2005084530A2 (en) 2004-03-06 2005-09-15 F. Hoffmann-La Roche Ag Body fluid sampling device
ATE553213T1 (de) * 2004-12-13 2012-04-15 Bayer Healthcare Llc Zusammensetzungen mit eigener grössenbegrenzung sowie testvorrichtungen zur messung von analyten in biologischen flüssigkeiten
PL1739432T3 (pl) 2005-06-29 2012-03-30 Hoffmann La Roche System analityczny z taśmą testującą
DE102005035461A1 (de) 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
JP4786451B2 (ja) * 2005-07-28 2011-10-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Nad/nadhの安定化
US20070196899A1 (en) 2005-11-29 2007-08-23 Sony Corporation Mutant protein having diaphorase activity
CN101058824A (zh) * 2006-04-21 2007-10-24 北京化工大学 固定化酶生物催化剂及其制备方法和应用
WO2007127981A2 (en) * 2006-04-28 2007-11-08 University Of Rochester Analyte-releasing beads and use thereof in quantitative elispot or fluorispot assay
KR100690930B1 (ko) * 2006-05-03 2007-03-09 한국기계연구원 깊은 제거를 이용하여 원하는 패턴 두께 혹은 높은종횡비를 가지는 고해상도 패턴 형성 방법
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CN101329268A (zh) * 2007-06-21 2008-12-24 苏州艾杰生物科技有限公司 蔗糖测定试剂盒及蔗糖的浓度测定方法
CN101329264A (zh) * 2007-06-21 2008-12-24 苏州艾杰生物科技有限公司 蔗糖酶诊断/测定试剂盒及蔗糖酶活性浓度测定方法
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EP2333544A1 (de) * 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt

Also Published As

Publication number Publication date
KR101506928B1 (ko) 2015-03-30
ES2544984T3 (es) 2015-09-07
US10260085B2 (en) 2019-04-16
US20130052674A1 (en) 2013-02-28
JP2013524770A (ja) 2013-06-20
CN102741694A (zh) 2012-10-17
KR20120102084A (ko) 2012-09-17
EP2513648B1 (de) 2015-05-27
HK1177501A1 (en) 2013-08-23
WO2011073258A1 (de) 2011-06-23
CN102741694B (zh) 2014-12-24
JP5777633B2 (ja) 2015-09-09
MX2012006706A (es) 2012-07-03
PL2513648T3 (pl) 2015-11-30
CA2782943A1 (en) 2011-06-23
EP2513648A1 (de) 2012-10-24

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