KR101492849B1 - 산화 저항성 지시약 분자 - Google Patents

산화 저항성 지시약 분자 Download PDF

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Publication number
KR101492849B1
KR101492849B1 KR1020097013639A KR20097013639A KR101492849B1 KR 101492849 B1 KR101492849 B1 KR 101492849B1 KR 1020097013639 A KR1020097013639 A KR 1020097013639A KR 20097013639 A KR20097013639 A KR 20097013639A KR 101492849 B1 KR101492849 B1 KR 101492849B1
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KR
South Korea
Prior art keywords
methyl
group
tetramethyl
benzyl
dioxaborolano
Prior art date
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KR1020097013639A
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English (en)
Korean (ko)
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KR20090097900A (ko
Inventor
아서 이 콜빈
마크 알란 모텔라로
아네타 모드젤레브스카
Original Assignee
센세오닉스, 인코포레이티드
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Application filed by 센세오닉스, 인코포레이티드 filed Critical 센세오닉스, 인코포레이티드
Publication of KR20090097900A publication Critical patent/KR20090097900A/ko
Application granted granted Critical
Publication of KR101492849B1 publication Critical patent/KR101492849B1/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Food Science & Technology (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020097013639A 2006-11-30 2007-11-30 산화 저항성 지시약 분자 KR101492849B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86170706P 2006-11-30 2006-11-30
US60/861,707 2006-11-30
US90329107P 2007-02-26 2007-02-26
US60/903,291 2007-02-26
PCT/US2007/024704 WO2008066921A2 (fr) 2006-11-30 2007-11-30 Molécules d'indicateur résistant à l'oxydation

Publications (2)

Publication Number Publication Date
KR20090097900A KR20090097900A (ko) 2009-09-16
KR101492849B1 true KR101492849B1 (ko) 2015-02-12

Family

ID=39284160

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097013639A KR101492849B1 (ko) 2006-11-30 2007-11-30 산화 저항성 지시약 분자

Country Status (14)

Country Link
US (2) US7851225B2 (fr)
EP (1) EP2099807B1 (fr)
JP (2) JP5517624B2 (fr)
KR (1) KR101492849B1 (fr)
CN (1) CN101541813B (fr)
AU (1) AU2007325650B2 (fr)
BR (1) BRPI0721056B8 (fr)
CA (1) CA2670457C (fr)
DK (1) DK2099807T3 (fr)
HK (1) HK1130262A1 (fr)
MX (1) MX2009005781A (fr)
SG (1) SG179448A1 (fr)
TW (1) TWI431100B (fr)
WO (1) WO2008066921A2 (fr)

Families Citing this family (26)

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Publication number Priority date Publication date Assignee Title
WO2005065241A2 (fr) * 2003-12-24 2005-07-21 Argose, Inc. Rapporteurs de metabolites a petites molecules destines a etre utilises comme biocapteurs de glucose in vivo
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
EP2536335A1 (fr) * 2010-02-19 2012-12-26 Glysure Ltd Capteur de glucose intravasculaire
WO2011133800A1 (fr) * 2010-04-23 2011-10-27 The Regents Of The University Of California Composés et procédés de détection d'espèces réactives de l'oxygène
EP2623530B1 (fr) * 2010-09-30 2015-03-04 Terumo Kabushiki Kaisha Hydrogel fluorescent, procédé pour sa fabrication et capteur pour mesurer des saccharides l'utilisant
AU2012229109A1 (en) 2011-03-15 2013-10-10 Senseonics, Incorporated Integrated catalytic protection of oxidation sensitive materials
US9051598B2 (en) * 2011-05-02 2015-06-09 The Hong Kong University Of Science And Technology Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor
MX341834B (es) * 2011-12-30 2016-09-05 Dow Agrosciences Llc Metodos de formacion de esteres pinacolicos de acido 4-cloro-2-fluoro-3-sustituido-fenilboronico y sus metodos de uso.
IN2014DN07535A (fr) 2012-03-15 2015-04-24 Lightship Medical Ltd
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
CN103694269B (zh) * 2013-11-27 2016-04-27 中国科学院上海微系统与信息技术研究所 一种可检测仲胺的化合物及其制备和应用
EP3180065A4 (fr) 2014-07-24 2018-04-11 Thomas Jefferson University Système de surveillance implantable à long terme et procédés d'utilisation
EP3484367B1 (fr) 2016-07-18 2022-01-05 Siemens Healthcare Diagnostics Inc. Prévention de l'encrassement biologique de capteurs portatif et étalonnage correspondant.
JP6758393B2 (ja) * 2016-09-30 2020-09-23 富士フイルム株式会社 高分子化合物
WO2018119204A1 (fr) 2016-12-21 2018-06-28 Profusa, Inc. Colorants polymérisables dans le proche infrarouge (ir)
JOP20190161A1 (ar) 2016-12-27 2017-06-16 Profusa Inc مستشعرات جلوكوز بطيف قريب من الأشعة تحت الحمراء
US10413658B2 (en) 2017-03-31 2019-09-17 Capillary Biomedical, Inc. Helical insertion infusion device
CN110730631B (zh) 2017-04-19 2023-02-21 传感技术股份有限公司 对分析物指示剂变化的检测和修正
EP4049032A1 (fr) 2019-10-25 2022-08-31 Cercacor Laboratories, Inc. Composés indicateurs, dispositifs comprenant des composés indicateurs, et leurs procédés de fabrication et d'utilisation
US11760170B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Olfaction sensor preservation systems and methods
US11828210B2 (en) 2020-08-20 2023-11-28 Denso International America, Inc. Diagnostic systems and methods of vehicles using olfaction
US11813926B2 (en) 2020-08-20 2023-11-14 Denso International America, Inc. Binding agent and olfaction sensor
US11636870B2 (en) 2020-08-20 2023-04-25 Denso International America, Inc. Smoking cessation systems and methods
US11881093B2 (en) 2020-08-20 2024-01-23 Denso International America, Inc. Systems and methods for identifying smoking in vehicles
US11932080B2 (en) 2020-08-20 2024-03-19 Denso International America, Inc. Diagnostic and recirculation control systems and methods
US11760169B2 (en) 2020-08-20 2023-09-19 Denso International America, Inc. Particulate control systems and methods for olfaction sensors

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503770A (en) * 1993-11-07 1996-04-02 Research Development Corporation Of Japan Fluorescent compound suitable for use in the detection of saccharides
WO2002057788A2 (fr) * 2001-01-05 2002-07-25 Sensors For Medicine And Science, Inc. Detection de glucose dans des solutions contenant egalement un acide alpha-hydroxy ou une beta-diketone
WO2003078424A1 (fr) 2002-03-14 2003-09-25 Sensors For Medicine And Science, Inc. Detection de glucose dans des solutions contenant egalement un acide $g(a)-hydroxy ou une $g(b)-dicetone
WO2004096817A1 (fr) 2003-03-28 2004-11-11 Terumo Corporation Of Japan Composes de detection de saccharides en phase solide

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024775D0 (en) * 1990-11-14 1991-01-02 Axis Research Chemical compounds
US6002954A (en) * 1995-11-22 1999-12-14 The Regents Of The University Of California Detection of biological molecules using boronate-based chemical amplification and optical sensors
DE69633573T2 (de) * 1995-11-22 2005-10-06 Medtronic MiniMed, Inc., Northridge Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
BR0112871A (pt) * 2000-08-04 2003-04-22 Sensors For Med & Science Inc Detecção de analitos para ambientes aquosos

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503770A (en) * 1993-11-07 1996-04-02 Research Development Corporation Of Japan Fluorescent compound suitable for use in the detection of saccharides
WO2002057788A2 (fr) * 2001-01-05 2002-07-25 Sensors For Medicine And Science, Inc. Detection de glucose dans des solutions contenant egalement un acide alpha-hydroxy ou une beta-diketone
WO2003078424A1 (fr) 2002-03-14 2003-09-25 Sensors For Medicine And Science, Inc. Detection de glucose dans des solutions contenant egalement un acide $g(a)-hydroxy ou une $g(b)-dicetone
WO2004096817A1 (fr) 2003-03-28 2004-11-11 Terumo Corporation Of Japan Composes de detection de saccharides en phase solide

Also Published As

Publication number Publication date
CN101541813A (zh) 2009-09-23
CA2670457C (fr) 2016-08-09
WO2008066921A3 (fr) 2008-07-17
TW200838985A (en) 2008-10-01
JP5517624B2 (ja) 2014-06-11
EP2099807A2 (fr) 2009-09-16
TWI431100B (zh) 2014-03-21
HK1130262A1 (en) 2009-12-24
CA2670457A1 (fr) 2008-06-05
DK2099807T3 (da) 2014-01-27
US20080145944A1 (en) 2008-06-19
AU2007325650B2 (en) 2012-07-12
MX2009005781A (es) 2009-06-10
BRPI0721056A2 (pt) 2017-05-16
JP2010511863A (ja) 2010-04-15
US8143068B2 (en) 2012-03-27
JP2013083658A (ja) 2013-05-09
EP2099807B1 (fr) 2014-01-01
AU2007325650A1 (en) 2008-06-05
US20110081727A1 (en) 2011-04-07
BRPI0721056B1 (pt) 2017-10-24
KR20090097900A (ko) 2009-09-16
WO2008066921A2 (fr) 2008-06-05
SG179448A1 (en) 2012-04-27
BRPI0721056B8 (pt) 2019-11-19
US7851225B2 (en) 2010-12-14
CN101541813B (zh) 2013-07-31

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