KR101479519B1 - 통증 및 염증 치료를 위한 비소 화합물의 용도 - Google Patents

통증 및 염증 치료를 위한 비소 화합물의 용도 Download PDF

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Publication number
KR101479519B1
KR101479519B1 KR1020097018389A KR20097018389A KR101479519B1 KR 101479519 B1 KR101479519 B1 KR 101479519B1 KR 1020097018389 A KR1020097018389 A KR 1020097018389A KR 20097018389 A KR20097018389 A KR 20097018389A KR 101479519 B1 KR101479519 B1 KR 101479519B1
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pain
inflammation
sodium
arsenate
treatment
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Korean (ko)
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KR20090122348A (ko
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마이클 황
양용진
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파나픽스 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/36—Arsenic; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
KR1020097018389A 2007-02-02 2008-02-01 통증 및 염증 치료를 위한 비소 화합물의 용도 Expired - Fee Related KR101479519B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89900707P 2007-02-02 2007-02-02
US60/899,007 2007-02-02
US12/068,006 US8945505B2 (en) 2007-02-02 2008-01-31 Use of arsenic compounds for treatment of pain and inflammation
US12/068,006 2008-01-31
PCT/US2008/052751 WO2008097824A2 (en) 2007-02-02 2008-02-01 Use of arsenic compounds for treatment of pain and inflammation

Publications (2)

Publication Number Publication Date
KR20090122348A KR20090122348A (ko) 2009-11-27
KR101479519B1 true KR101479519B1 (ko) 2015-01-08

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KR1020097018389A Expired - Fee Related KR101479519B1 (ko) 2007-02-02 2008-02-01 통증 및 염증 치료를 위한 비소 화합물의 용도

Country Status (18)

Country Link
US (2) US8945505B2 (enExample)
EP (1) EP2114419B8 (enExample)
JP (3) JP5411709B2 (enExample)
KR (1) KR101479519B1 (enExample)
CN (2) CN103550253A (enExample)
AR (1) AR065138A1 (enExample)
AU (1) AU2008214084C9 (enExample)
BR (1) BRPI0807154B8 (enExample)
CA (3) CA2845292C (enExample)
DK (1) DK2114419T3 (enExample)
ES (1) ES2460868T3 (enExample)
IL (3) IL200173A (enExample)
MX (1) MX2009008174A (enExample)
NZ (1) NZ578621A (enExample)
PL (1) PL2114419T3 (enExample)
RU (3) RU2630574C2 (enExample)
TW (1) TWI404538B (enExample)
WO (1) WO2008097824A2 (enExample)

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US20090061022A1 (en) * 2004-10-08 2009-03-05 Sang Bong Lee Pharmaceutical composition comprising arsenite for the treatment of malignancy
EP1721615A1 (en) 2005-05-09 2006-11-15 Komipharm International Co., Ltd. Pharmaceutical compositions comprising sodium or potassium arsenite for the treatment of urogenital cancer and its metastasis
US8045505B2 (en) * 2007-01-18 2011-10-25 Science Applications International Corporation Mechanism for automatic network formation and medium access coordination
WO2009109911A1 (en) 2008-03-04 2009-09-11 Pfizer Limited Methods of treating chronic pain
EP2432480B1 (en) * 2009-05-18 2021-05-05 The University of Hong Kong Compositions and methods for treating inflammatory arthritis
RU2535074C2 (ru) 2009-08-28 2014-12-10 Лэйбрис Байолоджикс, Инк. Способы лечения висцеральной боли путем введения антител-антагонистов, направленных против пептида, связанного с геном кальцитонина
PT2475362T (pt) * 2009-09-10 2019-05-27 Kominox Inc Terapia especifica para celulas estaminais cancerigenas e para 0 cancro resistente a medicamentos
FR3004949B1 (fr) * 2013-04-26 2016-02-05 Centre Nat Rech Scient Traitement de maladies autoimmunes et inflammatoires par les composes de l'arsenic as203 et/ou as205 administres par voie locale
RS65360B1 (sr) 2014-03-21 2024-04-30 Teva Pharmaceuticals Int Gmbh Antagonistička antitela specifična za peptid genski srodan kalcitoninu i postupci njihove upotrebe
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
KR102015858B1 (ko) * 2015-10-23 2019-08-30 손영태 법제된 비상을 함유하는 면역력 증강을 위한 약학적 조성물
AU2017331593B2 (en) 2016-09-23 2022-04-28 Teva Pharmaceuticals International Gmbh Treating refractory migraine
KR101834366B1 (ko) * 2016-11-21 2018-03-05 주식회사 케마스 육산화사비소의 결정다형을 포함하는 유방암 예방 또는 치료용 약학 조성물 및 이의 제조방법
KR101844049B1 (ko) 2016-12-05 2018-03-30 주식회사 케마스 육산화사비소의 결정다형을 포함하는 간암 예방 또는 치료용 약학 조성물
KR101844050B1 (ko) * 2016-12-09 2018-05-14 주식회사 케마스 육산화사비소의 결정다형을 포함하는 암 예방 또는 치료용 약학 조성물
CN106890353A (zh) * 2017-03-31 2017-06-27 应剑波 一种具有抗菌滋养功能的医用辅料
US10716807B2 (en) * 2017-05-09 2020-07-21 Medsenic Method of treating relapsing-remitting multiple sclerosis using arsenic trioxide
MA52088A (fr) * 2018-03-22 2021-01-27 Komipharm Int Australia Pty Ltd Composition pharmaceutique comprenant du méta-arsénite et procédé de fabrication
RU2687599C1 (ru) * 2018-11-22 2019-05-15 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Способ лечения постмастэктомического синдрома
CN109674817B (zh) * 2019-01-31 2021-06-29 哈尔滨医科大学 三氧化二砷在制备治疗晚期动脉粥样硬化药物中的用途
CN117085038A (zh) * 2019-05-21 2023-11-21 麦德赛尼克公司 金属离子增强砷的治疗作用的用途
CN115243692A (zh) * 2020-02-16 2022-10-25 科微范国际澳大利亚私人有限公司 使用偏亚砷酸盐的治疗方法
RU2755329C2 (ru) * 2020-03-13 2021-09-15 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ "РОССИЙСКИЙ НАУЧНЫЙ ЦЕНТР РАДИОЛОГИИ И ХИРУРГИЧЕСКИХ ТЕХНОЛОГИЙ ИМЕНИ АКАДЕМИКА А.М. ГРАНОВА" МИНИСТЕРСТВА ЗДРАВООХРАНЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ /ФГБУ "РНЦРХТ им. академика А.М. Гранова" Минздрава России Способ лечения нерезектабельной гилюсной холангиокарциномы
WO2021198535A1 (en) * 2020-04-03 2021-10-07 Medsenic Use of an arsenic compound for treating a short or long cytokine storm in various autoimmune/inflammatory diseases in humans or animals
EP3988093A1 (en) * 2020-10-22 2022-04-27 Medsenic Use of an arsenic compound for treating a cytokine storm
KR102240693B1 (ko) * 2020-05-18 2021-04-15 주식회사 케마스 육산화사비소를 포함하는 코로나바이러스 감염증의 예방 또는 치료용 약학조성물
KR20220020637A (ko) * 2020-08-12 2022-02-21 이상봉 항암화학요법이나 방사선요법으로 인한 암 환자의 탈모증을 포함한 탈모증 환자에 대하여 탈모를 방지하고 발모를 촉진하는 메타아르세나이트의 염을 함유하는 경구 투여용 약학적 조성물
KR20220020633A (ko) * 2020-08-12 2022-02-21 이상봉 탈모방지 또는 발모촉진용 주사제 조성물
CA3205138A1 (en) 2020-12-17 2022-06-23 Vertex Pharmaceuticals Incorporated Compositions and methods for editing beta-globin for treatment of hemaglobinopathies

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EP1736161A2 (en) * 2005-06-24 2006-12-27 Shao-Chi Hsin Use of an arsenic compound for the manufacture of a medicament for the treatment of arsenic susceptible blast-like cell related diseases

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Publication number Priority date Publication date Assignee Title
US20050163863A1 (en) * 2002-04-26 2005-07-28 Centre National De La Recherche Scientifique (Cnrs) Arsenic therapy for apls-type autoimmune lymph-oproliferative syndrome in mice and humans
EP1736161A2 (en) * 2005-06-24 2006-12-27 Shao-Chi Hsin Use of an arsenic compound for the manufacture of a medicament for the treatment of arsenic susceptible blast-like cell related diseases

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Publication number Publication date
AU2008214084B2 (en) 2013-10-31
CA2677388A1 (en) 2008-08-14
JP5411709B2 (ja) 2014-02-12
DK2114419T3 (da) 2014-06-10
CA2845299A1 (en) 2008-08-14
AU2008214084C9 (en) 2014-04-03
BRPI0807154A2 (pt) 2014-04-22
IL200173A0 (en) 2010-04-15
BRPI0807154B1 (pt) 2021-01-12
CN101641105A (zh) 2010-02-03
MX2009008174A (es) 2009-11-26
JP2010518022A (ja) 2010-05-27
IL217891A (en) 2014-05-28
JP2015007138A (ja) 2015-01-15
US10058570B2 (en) 2018-08-28
RU2012134218A (ru) 2014-02-20
NZ578621A (en) 2011-06-30
IL200173A (en) 2013-12-31
IL229255A0 (en) 2013-12-31
US20130309319A1 (en) 2013-11-21
CN103550253A (zh) 2014-02-05
US20080193560A1 (en) 2008-08-14
IL229255A (en) 2015-02-26
CA2845292C (en) 2017-09-12
BRPI0807154B8 (pt) 2021-05-25
KR20090122348A (ko) 2009-11-27
AR065138A1 (es) 2009-05-20
HK1138512A1 (en) 2010-08-27
RU2013151904A (ru) 2015-05-27
RU2009132951A (ru) 2011-03-10
AU2008214084A1 (en) 2008-08-14
JP2013147511A (ja) 2013-08-01
RU2468806C2 (ru) 2012-12-10
EP2114419A2 (en) 2009-11-11
ES2460868T3 (es) 2014-05-14
IL217891A0 (en) 2012-03-29
TW200843734A (en) 2008-11-16
PL2114419T3 (pl) 2014-10-31
CA2845299C (en) 2017-03-07
WO2008097824A3 (en) 2009-03-26
EP2114419B1 (en) 2014-04-09
CA2677388C (en) 2017-07-25
RU2665362C2 (ru) 2018-08-29
JP5853347B2 (ja) 2016-02-09
AU2008214084C1 (en) 2014-03-06
JP5825611B2 (ja) 2015-12-02
WO2008097824A2 (en) 2008-08-14
EP2114419B8 (en) 2014-06-11
RU2630574C2 (ru) 2017-09-11
TWI404538B (zh) 2013-08-11
US8945505B2 (en) 2015-02-03
CA2845292A1 (en) 2008-08-14

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