KR101185541B1 - 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도 - Google Patents

아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도 Download PDF

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KR101185541B1
KR101185541B1 KR1020057016343A KR20057016343A KR101185541B1 KR 101185541 B1 KR101185541 B1 KR 101185541B1 KR 1020057016343 A KR1020057016343 A KR 1020057016343A KR 20057016343 A KR20057016343 A KR 20057016343A KR 101185541 B1 KR101185541 B1 KR 101185541B1
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compounds
formula
ylvinyl
compound
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KR20060006006A (ko
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제프리 다니엘 슈미트
게리 모리스 덜
아리엘르 쥬느브아-보렐리아
마르끄 까페
미쉘 셰브
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타가셉트 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • A61P25/04—Centrally acting analgesics, e.g. opioids
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020057016343A 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도 Expired - Fee Related KR101185541B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/379,868 US7098331B2 (en) 2003-03-05 2003-03-05 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
US10/379,868 2003-03-05
PCT/US2004/006530 WO2004078752A1 (en) 2003-03-05 2004-03-04 Arylvinylazacycloalkane compounds and methods of preparation and use thereof

Related Child Applications (3)

Application Number Title Priority Date Filing Date
KR1020097002099A Division KR100953150B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020127001576A Division KR20120014236A (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020097002098A Division KR101018083B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도

Publications (2)

Publication Number Publication Date
KR20060006006A KR20060006006A (ko) 2006-01-18
KR101185541B1 true KR101185541B1 (ko) 2012-09-24

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KR1020057016343A Expired - Fee Related KR101185541B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020127001576A Ceased KR20120014236A (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020097002098A Expired - Fee Related KR101018083B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020097002099A Expired - Fee Related KR100953150B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도

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KR1020127001576A Ceased KR20120014236A (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020097002098A Expired - Fee Related KR101018083B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도
KR1020097002099A Expired - Fee Related KR100953150B1 (ko) 2003-03-05 2004-03-04 아릴비닐아자시클로알칸 화합물, 그 제조방법, 및 그 용도

Country Status (31)

Country Link
US (8) US7098331B2 (https=)
EP (3) EP1601670B1 (https=)
JP (3) JP4663627B2 (https=)
KR (4) KR101185541B1 (https=)
CN (3) CN100526308C (https=)
AR (3) AR043469A1 (https=)
AT (3) ATE496046T1 (https=)
AU (3) AU2004217903B2 (https=)
BR (1) BRPI0409576A (https=)
CA (1) CA2516514C (https=)
CL (1) CL2004000452A1 (https=)
CY (2) CY1110391T1 (https=)
DE (2) DE602004013553D1 (https=)
DK (2) DK1601670T3 (https=)
EA (3) EA010870B1 (https=)
ES (3) ES2385941T3 (https=)
GT (1) GT200400033A (https=)
IL (3) IL170155A (https=)
JO (1) JO2488B1 (https=)
MX (1) MXPA05009386A (https=)
NO (3) NO331920B1 (https=)
NZ (1) NZ541795A (https=)
PA (1) PA8597201A1 (https=)
PE (1) PE20040930A1 (https=)
PL (5) PL394600A1 (https=)
PT (2) PT1601670E (https=)
SI (2) SI1601670T1 (https=)
TW (3) TW200927746A (https=)
UY (1) UY28218A1 (https=)
WO (1) WO2004078752A1 (https=)
ZA (1) ZA200506790B (https=)

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WO2010080757A2 (en) 2009-01-07 2010-07-15 Astrazeneca Ab Combinations with an alpha-4beta-2 nicotinic agonist
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PH12012501068A1 (en) 2009-12-07 2013-02-04 Targacept Inc 3,6-diazabicyclo [3.1.1] heptanes as neuronal nicotinic acetylcholine receptor ligands
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US20140081714A1 (en) * 2012-09-19 2014-03-20 Salesforce.Com, Inc. Systems and methods of rewarding users in an on-demand system
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CN109310692B (zh) 2016-04-07 2022-01-25 奥伊斯特普安生物制药公司 治疗眼部病状的方法
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TW202019424A (zh) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之方法
TW202019417A (zh) 2018-07-10 2020-06-01 美商奧伊斯特普安生物製藥公司 治療眼部症狀之正向異位調節劑與菸鹼乙醯膽鹼受體促效劑之組合
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