KR101117673B1 - 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브 - Google Patents

암-관련 단백질을 표적으로 하는 알엔에이아이 프로브 Download PDF

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KR101117673B1
KR101117673B1 KR1020107028249A KR20107028249A KR101117673B1 KR 101117673 B1 KR101117673 B1 KR 101117673B1 KR 1020107028249 A KR1020107028249 A KR 1020107028249A KR 20107028249 A KR20107028249 A KR 20107028249A KR 101117673 B1 KR101117673 B1 KR 101117673B1
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cells
sirna
cancer
seq
clu
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KR20100135335A (ko
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브르크하르트 얀센
마틴 이. 글리브
막심 시냐프스키
엘리아나 베랄디
이오안니스 피. 트루가코스
에프스타치오스 에스. 고노스
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더 유니버시티 오브 브리티쉬 콜롬비아
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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/34—Spatial arrangement of the modifications
    • C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications

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KR1020107028249A 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브 Expired - Fee Related KR101117673B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US40519302P 2002-08-21 2002-08-21
US60/405,193 2002-08-21
US40815202P 2002-09-03 2002-09-03
US60/408,152 2002-09-03
US47238703P 2003-05-20 2003-05-20
US60/472,387 2003-05-20

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KR1020057002963A Division KR101212512B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브

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KR20100135335A KR20100135335A (ko) 2010-12-24
KR101117673B1 true KR101117673B1 (ko) 2012-03-07

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KR1020107028249A Expired - Fee Related KR101117673B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브
KR1020057002963A Expired - Fee Related KR101212512B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브
KR1020117025408A Expired - Fee Related KR101238701B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브

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KR1020057002963A Expired - Fee Related KR101212512B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브
KR1020117025408A Expired - Fee Related KR101238701B1 (ko) 2002-08-21 2003-08-21 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브

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US (5) US8252918B2 (enExample)
EP (2) EP1532249A2 (enExample)
JP (4) JP4717633B2 (enExample)
KR (3) KR101117673B1 (enExample)
AU (1) AU2003258426B2 (enExample)
CA (2) CA2494766C (enExample)
IL (3) IL166658A (enExample)
NO (2) NO334573B1 (enExample)
NZ (1) NZ552872A (enExample)
WO (1) WO2004018676A2 (enExample)

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US7285541B2 (en) 2002-08-21 2007-10-23 The University Of British Columbia Treatment of melanoma by reduction in clusterin levels
KR101117673B1 (ko) * 2002-08-21 2012-03-07 더 유니버시티 오브 브리티쉬 콜롬비아 암-관련 단백질을 표적으로 하는 알엔에이아이 프로브
US7635673B2 (en) 2003-03-25 2009-12-22 The Board Of Trustees Of The University Of Illinois Methods of inhibiting tumor cell proliferation
US20040220131A1 (en) * 2003-04-18 2004-11-04 The University Of British Columbia Method for treatment of cancerous angiogenic disorders
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CN106282185B (zh) * 2016-08-18 2020-06-26 广州市锐博生物科技有限公司 一种用于抑制簇集蛋白基因表达的成套siRNA及其应用
KR102923964B1 (ko) 2023-04-13 2026-02-09 한양대학교 에리카산학협력단 Igfbp5 돌연변이체 또는 이를 발현하는 벡터를 유효성분으로 포함하는 암 예방 또는 치료용 약학적 조성물
WO2024214933A1 (ko) * 2023-04-13 2024-10-17 한양대학교 에리카산학협력단 인산화된 igfbp5의 과도한 생성을 차단하여 암을 예방 또는 치료하는 방법
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EP2263679A2 (en) 2010-12-22
IL197159A (en) 2016-11-30
US7964717B2 (en) 2011-06-21
NZ552872A (en) 2007-11-30
US20080274996A1 (en) 2008-11-06
JP2011036267A (ja) 2011-02-24
KR20050042483A (ko) 2005-05-09
JP2013150624A (ja) 2013-08-08
KR101238701B1 (ko) 2013-03-05
US20110009472A1 (en) 2011-01-13
US20120202873A1 (en) 2012-08-09
NO334573B1 (no) 2014-04-14
JP5171887B2 (ja) 2013-03-27
KR101212512B1 (ko) 2012-12-26
JP2010193908A (ja) 2010-09-09
WO2004018676A2 (en) 2004-03-04
US20040096882A1 (en) 2004-05-20
US8252918B2 (en) 2012-08-28
AU2003258426A1 (en) 2004-03-11
EP1532249A2 (en) 2005-05-25
KR20100135335A (ko) 2010-12-24
AU2003258426B2 (en) 2008-04-10
CA2494766C (en) 2015-05-12
JP4717633B2 (ja) 2011-07-06
JP5662766B2 (ja) 2015-02-04
IL166658A0 (en) 2006-01-15
CA2882443A1 (en) 2004-03-04
US20060178329A1 (en) 2006-08-10
NO337130B1 (no) 2016-01-25
JP2006500958A (ja) 2006-01-12
US7820635B2 (en) 2010-10-26
NO20121038L (no) 2005-05-20
IL166658A (en) 2014-11-30
WO2004018676A3 (en) 2004-08-12
CA2882443C (en) 2016-12-13
IL197159A0 (en) 2011-07-31
IL233352A0 (en) 2014-08-31
US8759308B2 (en) 2014-06-24
EP2263679B1 (en) 2014-10-08
EP2263679A3 (en) 2011-10-12
NO20051423L (no) 2005-05-20
KR20110122883A (ko) 2011-11-11
US9487777B2 (en) 2016-11-08
CA2494766A1 (en) 2004-03-04

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