KR101085948B1 - Composite for hair promotion, manufacturing method thereof - Google Patents

Composite for hair promotion, manufacturing method thereof Download PDF

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KR101085948B1
KR101085948B1 KR1020090080910A KR20090080910A KR101085948B1 KR 101085948 B1 KR101085948 B1 KR 101085948B1 KR 1020090080910 A KR1020090080910 A KR 1020090080910A KR 20090080910 A KR20090080910 A KR 20090080910A KR 101085948 B1 KR101085948 B1 KR 101085948B1
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weight
parts
mixture
composition
hair growth
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KR20110023211A (en
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홍상근
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61K36/882Acoraceae (Calamus family), e.g. sweetflag or Acorus calamus
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract

본 발명은 발모촉진용 조성물과 그 제조방법에 관한 것으로, 구체적으로는 홍삼, 석창포, 백하수오, 다시마, 감초, 황련, 지골피, 원지, 고삼, 유근피를 분말화하여 혼합한 발모촉진용 조성물과 그 제조방법에 관한 것이다.The present invention relates to a composition for promoting hair growth and a method for manufacturing the same, specifically, red ginseng, Seokchangpo, Baekshou, kelp, licorice, rhubarb, phalanges, raw paper, red ginseng, rooted roots and powdered composition for promoting hair growth It relates to a manufacturing method.

본 발명은 홍삼 10~15중량부, 석창포 5~10중량부, 백하수오 5~10중량부, 다시마 5~10중량부, 감초 10~15중량부, 황련 10~15중량부, 지골피 5~15중량부, 원지 5~15중량부, 고삼 5~15중량부, 유근피 10~12중량부를 각각 분쇄한 후 혼합하여 얻어지는 제1 혼합물 제조단계(S11); 상기 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 6 내지 10배를 혼합하여 교반시킨 후, 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제 2~3중량부, 펩티아제 2~3중량부, 리파제2~3중량부를 투입하여 4~5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시켜 얻어지는 제2 혼합물 제조단계(S12); 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후 얻어지는 제3 혼합물 제조단계(S13) 및 상기 제3 혼합물을 감압농축기에 투입한 후, 90~120℃로 가열하여 농축시켜 30브릭스(brix) 이상 도달될 때까지 농축하여 얻어지는 제4 혼합물 제조단계(S14)를 포함한다.The present invention 10-15 parts by weight of red ginseng, 5-10 parts by weight of Seokchangpo, 5-10 parts by weight of Baekshou, 5-10 parts by weight of kelp, 10-15 parts by weight of licorice, 10-15 parts by weight of yellow lotus, phalanges 5-15 A first mixture manufacturing step (S11) obtained by pulverizing and mixing the parts by weight, 5 to 15 parts by weight of paper, 5 to 15 parts by weight of red ginseng, and 10 to 12 parts by weight of root skin; After stirring by mixing 6 to 10 times distilled water of 80 ° C ~ 100 ° C to the total weight of the first mixture, and extracted through an extractor to extract the extract of the first mixture, amylase 2-3 parts by weight , 2 to 3 parts by weight of peptase, 2 to 3 parts by weight of lipase, fermented for 4 to 5 hours, and then heated to 100 ° C. to remove the activity of the enzyme, followed by cooling at room temperature to ferment again to obtain a second mixture. (S12); A third mixture preparation step (S13) obtained after passing through a filtering system equipped with an activated carbon filter to remove fat component, phenol component or tannin component and remove inactive polymer carbohydrates and microorganisms in the second mixture. After the third mixture is put into a vacuum condenser, and heated to 90 ~ 120 ℃ concentrated to reach a brix 30 or more (brix) comprises a fourth mixture production step (S14) obtained.

본 발명의 발모촉진용 조성물과 그 제조방법에 의하면, 홍삼, 백하수오, 석창포, 지골피, 원지, 감초, 황련, 유근피, 고삼, 다시마 내에 함유되어 있는 생리활성 물질을 추출하여 제조하는 조성물이 발모촉진 효과가 있는 것으로 나타남으로써 부작용이 전혀 없는 발모효능을 가진 화장품과 주로 피부도표용으로 이용되는 의약부외품 형태로의 제품 개발이 가능하다. 이러한 조성물은 인체 내에서 흡수되어 모근 세포의 성장을 촉진시키는 영양성분을 공급할 뿐만 아니라 모근 세포 주위의 혈관을 활성화시킴으로써 혈액을 통한 인체 내분비계 호르몬 공급을 원활히 하는 효과 또한 기대할 수 있다. 또한, 두피의 모공주위의 비활성화 되고 축적된 지방질과 오염물질들을 제거하여 모근 세포가 모공을 통한 산소호흡을 원활하게 하는 효과가 있으며 두피의 내, 외부에 존재하는 알레르기 및 각종 염증 유발성 세균과 곰팡이 균을 살해시켜 두피의 피부 염증을 억제, 치유함으로써 건강한 두피를 유지하도록 한다. 그리고 비단 이러한 세균성 염증뿐만 아니라 염색 약 등 각종 모발관련 화학제품의 부작용을 억제할 수 있는 효과를 기대할 수 있어 본 발명의 조성물을 이용한 샴푸, 린스, 토닉 등의 화장품으로의 용도 개발이 가능하며 인체 임상을 통하여 두피를 포함한 피부 염증 치료제 등의 의약부외품으로도 개발이 가능한 큰 효과가 있는 것이다. According to the composition for promoting hair growth of the present invention and a method for producing the same, a composition for extracting and preparing a bioactive substance contained in red ginseng, white sewage, Seokchangpo, Jigolpi, Wonji, licorice, rhubarb, Yugeunpi, Gosam and kelp As it appears to be effective, it is possible to develop products in the form of cosmetics having no hair growth effect and no quasi-drugs mainly used for skin diagram. Such a composition can be expected to be effective in facilitating the supply of human endocrine hormones through the blood by activating blood vessels around the hair root cells as well as supplying nutrients that are absorbed in the human body to promote hair root cell growth. Also, by removing inactivated and accumulated fat and pollutants around the pores of the scalp, hair root cells have the effect of smoothing the oxygen respiration through the pores, and allergic and various inflammation-causing bacteria and fungi existing inside and outside the scalp. By killing the bacteria to suppress and heal the skin inflammation of the scalp to maintain a healthy scalp. In addition, it is possible to expect the effect of suppressing the side effects of various hair-related chemical products such as dyeing agents as well as such bacterial inflammation, and it is possible to develop the use as a cosmetic such as shampoo, rinse, and tonic using the composition of the present invention. Through the quasi-drugs and other quasi-drugs, including the treatment of skin inflammation, there is a great effect possible.

탈모, 탈모방지, 샴푸, 의약품 Hair loss, hair loss prevention, shampoo, medicine

Description

발모촉진용 조성물과 그 제조방법{Composite for hair promotion, manufacturing method thereof}Composition for promoting hair growth and a method for manufacturing the same {Composite for hair promotion, manufacturing method

본 발명은 발모촉진용 조성물과 그 제조방법에 관한 것으로, 구체적으로는 홍삼, 석창포, 백하수오, 다시마, 감초, 황련, 지골피, 원지, 고삼, 유근피를 분말화하여 혼합한 발모촉진용 조성물과 그 제조방법에 관한 것이다.The present invention relates to a composition for promoting hair growth and a method for manufacturing the same, specifically, red ginseng, Seokchangpo, Baekshou, kelp, licorice, rhubarb, phalanges, raw paper, red ginseng, rooted roots and powdered composition for promoting hair growth It relates to a manufacturing method.

탈모는 유전적, 환경적, 정신적 요소 등 다양한 요인으로 인해 두피의 모세혈관이 수축되면서 가려움 증세와 함께 두피조직으로부터 머리카락이 이탈되는 현상을 말하며, 이는 현대인들의 말 못하는 고민거리 중 하나로 자리 잡고 있다. Hair loss refers to a phenomenon in which the capillaries of the scalp are contracted due to various factors such as genetic, environmental, and mental factors, and itching and hair detachment from the scalp tissue, which is one of the unspeakable anxieties of modern people.

이와 같은 탈모의 원인은 내분비순환계의 기능 약화로 인해, 성장기까지 모근 세포의 생명력과 재생능력에 밀접한 내분비 순환계(발모 생장호르몬 분비 촉진인자)의 기능이 활발하다가 장년기와 노년기에 이르러 급격히 생장호르몬 분비가 감소함에 따라 서서히 탈모현상이 발생한다.The cause of such hair loss is due to the weakening of the function of the endocrine circulation, the function of the endocrine circulatory system (promoting the growth hormone secretion of growth hormone), which is closely related to the vitality and regeneration of hair root cells until the growth stage, and the growth hormone secretion rapidly increases in the elderly and old age. As it decreases, hair loss gradually occurs.

그리고 과도한 정신적 스트레스와 두뇌 노동 그리고 인스턴트화 된 식생활로 인하여 두피 내 원활하지 못한 혈액 순환과 모근 세포의 영양결핍 및 내분비순환계의 기능저하를 초래하여 사멸하는 모근 세포 수에 비해 생장하는 모근 세포의 수가 현격히 감소하여 성장기 중이라도 조기 탈모현상이 발생한다.In addition, excessive mental stress, brain labor, and instantaneous diet lead to poor blood circulation in the scalp, malnutrition of the hair follicle cells, and deterioration of the endocrine circulation, resulting in a significant number of hair follicle cells growing compared to the number of dying hair follicle cells. Premature hair loss occurs even during the growth phase.

또한, 유전적 탈모 요인을 지닌 경우는 남성 호르몬인 프로게스테론이 두피 내 활성화된 특정효소와 반응하여 탈모현상이 발생하는 것을 방해하는 내분비순환계의 발모 생장호르몬 분비기능이 저하되면 성장기 중에 유전적 요인으로 인한 조기 탈모 현상이 발생한다.In addition, in case of genetic hair loss factor, when the male hormone progesterone reacts with the specific enzyme activated in the scalp, the endocrine growth hormone secretion function of the endocrine circulatory system that prevents hair loss occurs, Premature hair loss occurs.

한편, 상기한 탈모 요인 외에도 질병, 약물 복용으로 인한 부작용, 여성의 경우 지나친 다이어트, 임신, 출산 등으로 인한 호르몬 분비의 불균형, 과다한 머리염색, 강한 광선에 과다 노출된 경우 등에도 탈모 현상이 발생할 수 있다. 게다가 현대사회의 복잡한 생활패턴과 환경에서 위의 네 가지 탈모요인이 복합적으로 작용함으로 남녀노소를 불문하고 탈모 현상이 발생하는 문제점이 있다. On the other hand, in addition to the above-mentioned hair loss factors, hair loss may also occur due to diseases, side effects from taking medications, imbalance of hormone secretion due to excessive diet, pregnancy, and childbirth, excessive hair dyeing, and excessive exposure to strong rays. have. In addition, the above four hair loss factors work in a complex life pattern and environment of modern society, which causes hair loss regardless of gender, age or gender.

본 발명은 상기한 문제점을 해결하기 위해 발명된 것으로, 그 목적은 생약성분을 이용하여 인체에 무리가 없으며, 발모를 촉진시키는 발모촉진용 조성물과 그 제조방법을 제공하는데 그 목적이 있다.The present invention has been invented to solve the above problems, its purpose is to provide a composition for promoting hair growth and a method of manufacturing the same to promote the human hair using the herbal ingredients.

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상기한 기술적 과제를 달성하기 위한 본 발명에 따른 발모촉진용 조성물 및 그 제조방법은 홍삼 10~15중량부, 석창포 5~10중량부, 백하수오 5~10중량부, 다시마 5~10중량부, 감초 10~15중량부, 황련 10~15중량부, 지골피 5~15중량부, 원지 5~15중량부, 고삼 5~15중량부, 유근피 10~12중량부를 각각 분쇄한 후 혼합하여 얻어지는 제1 혼합물 제조단계와, 상기 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 6 내지 10배를 혼합하여 교반시킨 후, 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제 2~3중량부, 펩티아제 2~3중량부, 리파제2~3 중량부를 투입하여 4~5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시켜 얻어지는 제2 혼합물 제조단계와, 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후 얻어지는 제3 혼합물 제조단계 및 상기 제3 혼합물을 감압농축기에 투입한 후, 90~120℃로 가열하여 농축시켜 30브릭스(brix) 이상 도달될 때까지 농축하여 얻어지는 제4 혼합물 제조단계를 포함한다.
또한, 본 발명에 따른 발모촉진용 조성물 및 그 제조방법은 제4 혼합물 제조단계를 거쳐 발모촉진 효능을 목적으로 제조되는 샴푸, 린스 또는 토닉에 이용하는 것을 특징으로 한다.
또한, 본 발명에 따른 발모촉진용 조성물 및 그 제조방법은 제4 혼합물 제조단계를 거쳐 발모촉진 효능을 목적으로 제조되는 의약품 또는 의약부외품으로 이용하는 것을 특징으로 한다.
Hair growth promoting composition and a method for producing the same according to the present invention for achieving the above technical problem is 10 to 15 parts by weight of red ginseng, 5 to 10 parts by weight of Seokchangpo, 5 to 10 parts by weight of white sewage, 5 to 10 parts by weight of kelp, Licorice 10-15 parts by weight, 10-15 parts by weight of yellow lotus, 5-15 parts by weight of phalanges, 5-15 parts by weight of raw paper, 5-15 parts by weight of red ginseng, 10-12 parts by weight of root skin After mixing the mixture and stirring 6 to 10 times distilled water of 80 ° C. to 100 ° C. in the total weight of the first mixture, and then extracting the extract of the first mixture through an extractor, amylase 2 to 3 parts by weight, 2 to 3 parts by weight of peptase, and 2 to 3 parts by weight of lipase are added and fermented for 4 to 5 hours, and then heated to 100 ° C. to remove the activity of the enzyme, followed by cooling at room temperature to obtain fermentation again. Preparing a second mixture, and in the second mixture, a fatty component, a phenol component or tannin After passing through a filtering system equipped with an activated carbon filter to remove the inert polymer carbohydrates and microorganisms and the third mixture prepared step and the third mixture into a reduced pressure concentrator, and then to 90 ~ 120 ℃ Heating and concentrating to obtain a fourth mixture obtained by concentrating until reaching 30 brix or more.
In addition, the hair growth promoting composition and a method for manufacturing the same according to the present invention is characterized in that it is used in the shampoo, rinse or tonic produced for the purpose of promoting hair growth through the fourth mixture manufacturing step.
In addition, the hair growth promoting composition and a method for producing the same according to the present invention is characterized in that it is used as a drug or quasi-drug manufactured for the purpose of promoting hair growth through the fourth mixture manufacturing step.

본 발명의 발모촉진용 조성물과 그 제조방법에 의하면, 홍삼, 백하수오, 석창포, 지골피, 원지, 감초, 황련, 유근피, 고삼, 다시마 내에 함유되어 있는 생리활성 물질을 추출하여 제조하는 조성물이 발모촉진 효과가 있는 것으로 나타남으로써 부작용이 전혀 없는 발모효능을 가진 화장품과 주로 피부도표용으로 이용되는 의약부외품 형태로의 제품 개발이 가능하다. 이러한 조성물은 인체 내에서 흡수되어 모근 세포의 성장을 촉진시키는 영양성분을 공급할 뿐만 아니라 모근 세포 주위의 혈관을 활성화시킴으로써 혈액을 통한 인체 내분비계 호르몬 공급을 원활히 하는 효과 또한 기대할 수 있다. According to the composition for promoting hair growth of the present invention and a method for producing the same, a composition for extracting and preparing a bioactive substance contained in red ginseng, white sewage, Seokchangpo, Jigolpi, Wonji, licorice, rhubarb, Yugeunpi, Gosam and kelp As it appears to be effective, it is possible to develop products in the form of cosmetics having no hair growth effect and no quasi-drugs mainly used for skin diagram. Such a composition can be expected to be effective in facilitating the supply of human endocrine hormones through the blood by activating blood vessels around the hair root cells as well as supplying nutrients that are absorbed in the human body to promote hair root cell growth.

또한, 두피의 모공주위의 비활성화 되고 축적된 지방질과 오염물질들을 제거하여 모근 세포가 모공을 통한 산소호흡을 원활하게 하는 효과가 있으며 두피의 내, 외부에 존재하는 알레르기 및 각종 염증 유발 성 세균과 곰팡이 균을 살해시켜 두피의 피부 염증을 억제, 치유함으로써 건강한 두피를 유지하도록 한다. 그리고 비단 이러한 세균성 염증뿐만 아니라 염색 약 등 각종 모발관련 화학제품의 부작용을 억제할 수 있는 효과를 기대할 수 있어 본 발명의 조성물을 이용한 샴푸, 린스, 토닉 등의 화장품으로의 용도 개발이 가능하며 인체 임상을 통하여 두피를 포함한 피부 염증 치료제 등의 의약부외품으로도 개발이 가능한 큰 효과가 있는 것이다. In addition, it removes fat and contaminants around the pores of the scalp and removes accumulated fats and contaminants, so that the hair root cells facilitate oxygen breathing through the pores. By killing the bacteria to suppress and heal the skin inflammation of the scalp to maintain a healthy scalp. In addition, it is possible to expect the effect of suppressing the side effects of various hair-related chemical products such as dyeing agents as well as such bacterial inflammation, and it is possible to develop the use as a cosmetic such as shampoo, rinse, and tonic using the composition of the present invention. Through the quasi-drugs and other quasi-drugs, including the treatment of skin inflammation, there is a great effect possible.

본 발명을 충분히 이해하기 위해서 본 발명의 바람직한 실시예를 첨부 도면을 참조하여 설명한다. 본 발명의 실시예는 여러 가지 형태로 변형될 수 있으며, 본 발명의 범위가 아래에서 상세히 설명하는 실시예로 한정되는 것으로 해석되어서는 안 된다. 본 실시예는 당업계에서 평균적인 지식을 가진 자에게 본 발명을 보다 완전하게 설명하기 위하여 제공 되는 것이다. 또한, 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 공지 기능 및 구성에 대한 상세한 기술은 생략된다.In order to fully understand the present invention, preferred embodiments of the present invention will be described with reference to the accompanying drawings. Embodiment of the present invention may be modified in various forms, the scope of the invention should not be construed as limited to the embodiments described in detail below. This embodiment is provided to more completely explain the present invention to those skilled in the art. In addition, detailed descriptions of well-known functions and configurations that are determined to unnecessarily obscure the subject matter of the present invention are omitted.

이하, 본 발명의 바람직한 실시예를 설명함으로써, 본 발명의 발모촉진용 조성물과 그 제조방법을 상세히 설명한다.Hereinafter, by describing a preferred embodiment of the present invention, the composition for promoting hair growth of the present invention and its manufacturing method will be described in detail.

본 발명의 발모촉진용 조성물은, 홍삼 10~15중량부, 석창포 5~10중량부, 백하수오 5~10중량부, 다시마 5~10중량부, 감초 10~15중량부, 황련 10~15중량부, 지골피 5~15중량부, 원지 5~15중량부, 고삼 5~15중량부, 유근피 10~12중량부를 각각 분쇄한 후 혼합하여 얻어지는 제1 혼합물과, 상기 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 6 내지 10배를 혼합하여 교반시킨 후, 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제 2~3중량부, 펩티아제 2~3중량부, 리파제2~3 중량부를 투입하여 4~5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시켜 얻어지는 제2 혼합물과, 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후 얻어지는 제3 혼합물 및 상기 제3 혼합물을 감압농축기에 투입한 후, 90~120℃로 가열하여 농축 시켜 30브릭스(brix) 이상 도달될 때까지 농축시켜 얻어지는 제4 혼합물을 제조하는 공정을 통하여 제조되는 것이다. The hair growth promoting composition of the present invention, 10-15 parts by weight of red ginseng, 5-10 parts by weight of Seokchangpo, 5-10 parts by weight of white sewage, 5-10 parts by weight of kelp, 10-15 parts by weight of licorice, 10-15 weight of yellow lotus 5-15 parts by weight, 5-15 parts by weight of raw paper, 5-15 parts by weight of red ginseng, and 10-12 parts by weight of dried root skin, respectively, after crushing and mixing the first mixture and the total weight of the first mixture. After stirring by mixing 10 to 10 times distilled water of 80 ° C to 100 ° C, and extracting the extract of the first mixture through an extractor, 2-3 parts by weight of amylase, 2-3 parts by weight of peptase , 2 to 3 parts by weight of lipase, fermented for 4 to 5 hours, heated to 100 ° C. to remove enzyme activity, cooled to room temperature and fermented again to obtain a second mixture and a fat component and phenol in the second mixture. Activated carbon to remove components or tannins and remove inactive polymer carbohydrates and microorganisms The third mixture obtained after passing through a filtering system equipped with a filter and the third mixture is put into a vacuum condenser, and then heated to 90 ~ 120 ℃ concentrated to reach a concentration of 30 brix (brix) or more 4 is prepared through the process of preparing a mixture.

상기와 같이 제조되는 조성물은 샴푸, 린스, 토닉 등의 화장품으로, 또는 의약품 또는 의약부외품에 함유시켜 사용할 수 있는 것이다.The composition prepared as described above may be used in cosmetics such as shampoo, rinse, tonic, or in a medicine or quasi-drug.

이하, 상기와 같이 생성되는 조성물의 제조방법에 대해 설명하기로 한다. Hereinafter, a method of preparing the composition produced as described above will be described.

홍삼 10~15중량부, 석창포 5~10중량부, 백하수오 5~10중량부, 다시마 5~10중량부, 감초 10~15중량부, 황련 10~15중량부, 지골피 5~15중량부, 원지 5~15중량부, 고삼 5~15중량부, 유근피 10~12중량부를 각각 분쇄한 후 혼합하여 얻어지는 제1 혼합물 제조단계(S11)와, 상기 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 6 내지 10배를 혼합하여 교반시킨 후, 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제 2~3중량부, 펩티아제 2~3중량부, 리파제2~3 중량부를 투입하여 4~5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시켜 얻어지는 제2 혼합물 제조단계(S12)와, 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후 얻어지는 제3 혼합물 제조단계(S13) 및 상기 제3 혼합물을 감압농축기에 투입한 후, 90~120℃로 가열하여 농축 시켜 30브릭스(brix) 이상 도달될 때까지 농축하여 얻어지는 제4 혼합물 제조단계(S14)를 거쳐 조성물이 완성되는 것이다.Red ginseng 10-15 parts by weight, 5-10 parts by weight of Seokchangpo, 5-10 parts by weight of Baek Sewao, 5-10 parts by weight of kelp, 10-15 parts by weight of licorice, 10-15 parts by weight of yellow lotus, 5-15 parts by weight of phalanges, 5 to 15 parts by weight of raw paper, 5 to 15 parts by weight of red ginseng, and 10 to 12 parts by weight of dried root skin, respectively, after the first mixture is obtained by mixing (S11) and the total weight of the first mixture is 80 ° C. to 100 parts 6 to 10 times of distilled water was mixed and stirred, and then extracted through an extractor in order to extract the extract of the first mixture, followed by 2-3 parts by weight of amylase, 2-3 parts by weight of peptase, and 2 ~ lipase. After adding 3 parts by weight to fermentation for 4 to 5 hours, and heated to 100 ℃ to remove the activity of the enzyme and then cooled at room temperature to obtain a second mixture prepared step (S12) and the second component in the fat component, Activated carbon filter to remove phenol or tannins and remove inert polymer carbohydrates and microorganisms After passing through the filtering system is provided with a third mixture manufacturing step (S13) and the third mixture is put into a vacuum concentrator, and heated to 90 ~ 120 ℃ concentrated until reaching 30 brix (brix) or more The composition is completed through the fourth mixture preparation step (S14) obtained by concentrating.

상기한 바와 같이, 제4 혼합물 제조단계를 거쳐 제조되는 조성물은 샴푸, 린스, 토닉 등의 화장품으로, 또는 의약품 또는 의약부외품에 함유시켜 사용할 수 있는 것이다.As described above, the composition prepared through the fourth mixture manufacturing step may be used as a cosmetic such as shampoo, rinse, tonic, or in a medicine or quasi-drug.

이하, 본 발명에 따른 발모촉진용 조성물을 제조하는 실시예 및 첨부되는 도면을 통하여 더욱 상세히 설명한다. 그러나 이들 실시예는 본 발명을 예시하기 위한 것이며, 본 발명이 이들 실시예에 의해 한정되는 것은 아니다. Hereinafter, an embodiment for preparing a composition for promoting hair growth according to the present invention will be described in more detail with reference to the accompanying drawings. However, these examples are for illustrating the present invention, and the present invention is not limited by these examples.

<실시예><Examples>

홍삼 10중량부, 석창포 5중량부, 백하수오 5중량부, 다시마 5중량부, 감초 10중량부, 황련 10중량부, 지골피 5중량부, 원지 5중량부, 고삼 5중량부, 유근피 10중량부를 각각 분쇄한 후 혼합하여 제1 혼합물을 제조하고, 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 7배를 혼합하여 교반시킨 후, 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제, 펩티아제, 리파제 2중량부를 투입하여 5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시키고, 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후, 상기 혼합물을 감압농축기에 투입한 후, 100℃로 가열하여 농축 시켜 30브릭스(brix)로 도달될 때까지 농축시켜 얻어지는 조성물을 제조한다. 10 parts by weight of red ginseng, 5 parts by weight of Seokchangpo, 5 parts by weight of Baek Shou, 5 parts by weight of kelp, 10 parts by weight of licorice, 10 parts by weight of rye, 5 parts by weight of phalanges, 5 parts by weight of raw paper, 5 parts by weight of red ginseng, 10 parts by weight of root The mixture was pulverized and mixed to prepare a first mixture. The mixture was stirred by mixing 7 times distilled water of 80 ° C. to 100 ° C. with a total weight of the first mixture, and then extracting the extract of the first mixture through an extractor. After extraction, 2 parts by weight of amylase, peptase, and lipase were added and fermented for 5 hours, and then heated to 100 ° C. to remove the activity of the enzyme, and then cooled again at room temperature to ferment again. After removing the components or tannins, and passing through a filtering system equipped with an activated carbon filter to remove inactive polymer carbohydrates and microorganisms, the mixture was introduced into a vacuum concentrator, and then heated to 100 ° C and concentrated. To obtain a composition obtained by concentrating until reaching 30 brix.

<실험예>Experimental Example

상기와 같은 생성되는 발모촉진 조성물을 검증하기 위하여 다음과 같이 효능실험을 수행하였다.Efficacy experiment was performed as follows to verify the hair growth promoting composition produced as described above.

- 실험동물-Experimental animals

mouse(C57BL-6) 6주령 수컷 35마리를 이용하여 1주일간 사육조건에 적응시킨 후 실험에 사용하였다. 실험 기간까지 실험동물의 유지 및 관리는 독립된 동물실험실에서 최적의 조건을 유지하여 사육하였다.35 mice (C57BL-6) 6-week-old were used in the experiment after adapting to breeding conditions for 1 week. The maintenance and management of the experimental animals until the experimental period was maintained under optimal conditions in the independent animal laboratory.

1. 시료투여 1. Sample administration

실험은 대조군, 경피 도포군 2개 군으로 각 16, 19 마리씩 총 35마리를 사용하였다. 경피 도포방법은 홍삼 및 생약재 유래 발모촉진 기능을 지닌 조성물을 스프레이로 일정량 분무하여 피부에 도포하였고 대조군은 같은 스트레스를 주기 위하여 증류수를 스프레이로 일정량 도포하였다.In the experiment, a total of 35 rats, 16 and 19 rats, were used in two groups, a control group and a transdermal application group. Transdermal coating method was applied to the skin by spraying a certain amount of red ginseng and herbal medicine-derived hair growth promoting function with a spray, and the control group was applied with a certain amount of distilled water in order to give the same stress.

2. 체모성장비교 2. Hair growth equipment bridge

실험 전 등쪽 체모를 도 1에 도시된 바와 같이 animal clipper로 짧게 제거하여 제모 하였다. 모든 실험동물의 발모를 일정하게 억제시키기 위하여 1% 테스토 스테론(in ethanol)을 솜에 적셔서 제모 부위에 1주간 도포하였다. 테스토스테론 경피 도포 후 홍삼 및 생약 재 유래 발모촉진 기능을 지닌 조성물이 함유된 액체시료를 도포하기 시작하였다. 성장한 체모의 길이는 시료 투여 후 49일째 되는 날 육안으로 판별하여 체모성장 지수를 측정하여 수치화 하였다(표1 참조). 이외에 도 1 내지 도 2를 참조하여 육안으로 구별케 하였다.Before the experiment, the dorsal hair was removed by short hair removal with an animal clipper as shown in FIG. 1. In order to constantly suppress hair growth of all experimental animals, 1% testosterone (in ethanol) was soaked in cotton and applied to the hair removal site for 1 week. After the testosterone transdermal application, a liquid sample containing red ginseng and herbal hair-derived hair growth promoting composition was started. The length of the grown hair was visually determined on the 49th day after sample administration and quantified by measuring the hair growth index (see Table 1). In addition, with reference to FIGS. 1 to 2 were visually distinguished.

(표1)(Table 1)

발모지수Hair Growth Index 00 1One 22 33 44 성장없음No growth 약간의
발모
Slightly
Hair growth
1/3정도
발모
1/3
Hair growth
2/3이상
발모
2/3 or more
Hair growth
완전
발모
very
Hair growth

- 발모촉진 조성물의 효능 실험결과(완전 발모율) --Efficacy test result of hair growth promoting composition (complete hair growth rate)-

발모지수/실험군(마리수)Hair Growth Index / Experiment Group 00 1One 22 33 44 평균Average 완전
발모율
very
Hair growth rate
정상 대조군 (16)Normal control (16) 22 77 22 22 33 1.811.81 18.8%18.8% 경피 도포군 (19)Transdermal Applicator (19) 00 1One 1One 66 1111 3.423.42 57.9%57.9% 발 모 효 과Hair growth effect 89%89%

도 2에 도시된 바와 같이, CHBL-6 mouse를 이용한 실험에서 완전 발모된 마리수가 4배가량 증가하는 결과를 보였고 발모 지수를 비교한 결과 발모효과가 89%가량 증가하는 것으로 분석되어 홍삼 및 생약에서 추출한 조성물의 발모 촉진효과가 상당히 있는 것으로 판단된다.As shown in Figure 2, in the experiment using CHBL-6 mouse showed that the number of full-grown horses increased by about four times, and the hair growth effect was analyzed to increase by 89% as compared to the hair growth index in red ginseng and herbal medicine It is thought that the hair growth promoting effect of the extracted composition is significant.

이상에서 설명된 본 발명의 발모촉진용 조성물과 그 제조방법의 실시예는 예시적인 것에 불과하며, 본 발명이 속한 기술분야의 통상의 지식을 가진 자라면 이로부터 다양한 변형 및 균등한 타 실시예가 가능하다는 점을 잘 알 수 있을 것이다. 그러므로 본 발명은 상기의 상세한 설명에서 언급되는 형태로만 한정되는 것은 아님을 잘 이해할 수 있을 것이다. 따라서 본 발명의 진정한 기술적 보호 범위는 첨부된 특허청구범위의 기술적 사상에 의해 정해져야 할 것이다. 또한, 본 발명은 첨부된 청구범위에 의해 정의되는 본 발명의 정신과 그 범위 내에 있는 모든 변형물과 균등물 및 대체물을 포함하는 것으로 이해되어야 한다.Examples of the composition for promoting hair growth of the present invention described above and a method for manufacturing the same are merely exemplary, and those skilled in the art to which the present invention pertains may various modifications and other equivalent embodiments therefrom. You can see that. Therefore, it will be understood that the present invention is not limited to the forms mentioned in the above detailed description. Therefore, the true technical protection scope of the present invention will be defined by the technical spirit of the appended claims. It is also to be understood that the present invention includes all modifications, equivalents, and substitutes within the spirit and scope of the invention as defined by the appended claims.

발모촉진용 조성물과 그 제조방법은, 탈모로 인해 고생하는 사람들에게 널리 이용가능한 것이다.The hair growth promoting composition and its manufacturing method are widely available to those who suffer from hair loss.

도 1은 본 발명의 발모촉진용 조성물을 도포 하지 않은 쥐의 사진을 나타낸 모습이다.1 is a view showing a photograph of a rat not applied to the hair growth promoting composition of the present invention.

도 2는 본 발명의 발모촉진용 조성물을 도포한 쥐의 사진을 나타낸 모습이다.Figure 2 is a view showing a photograph of a rat coated with the composition for promoting hair growth of the present invention.

Claims (7)

삭제delete 삭제delete 삭제delete 홍삼 10~15중량부, 석창포 5~10중량부, 백하수오 5~10중량부, 다시마 5~10중량부, 감초 10~15중량부, 황련 10~15중량부, 지골피 5~15중량부, 원지 5~15중량부, 고삼 5~15중량부, 유근피 10~12중량부를 각각 분쇄한 후 혼합하여 얻어지는 제1 혼합물 제조단계(S11);Red ginseng 10-15 parts by weight, 5-10 parts by weight of Seokchangpo, 5-10 parts by weight of Baek Sewao, 5-10 parts by weight of kelp, 10-15 parts by weight of licorice, 10-15 parts by weight of yellow lotus, 5-15 parts by weight of phalanges, 5 to 15 parts by weight of raw paper, 5 to 15 parts by weight of red ginseng, and 10 to 12 parts by weight of dried root skin, each of which is obtained by pulverizing and mixing the first mixture (S11); 상기 제1 혼합물의 총 중량부에 80℃~100℃의 증류수를 6 내지 10배를 혼합하여 교반시킨 후, 상기 제1 혼합물의 엑기스를 추출하기 위하여 추출기를 통하여 추출시킨 후, 아밀라아제 2~3중량부, 펩티아제 2~3중량부, 리파제2~3중량부를 투입하여 4~5시간 발효시킨 후, 100℃로 가열하여 효소의 활성을 제거한 후 실온에서 냉각하여 다시 발효시켜 얻어지는 제2 혼합물 제조단계(S12);After stirring by mixing 6 to 10 times the distilled water of 80 ℃ ~ 100 ℃ to the total weight of the first mixture, and extracted through an extractor to extract the extract of the first mixture, amylase 2-3 weight 2 parts to 3 parts by weight of peptase and 2 parts to 3 parts by weight of lipase were fermented for 4 to 5 hours, and then heated to 100 ° C. to remove the activity of the enzyme, followed by cooling at room temperature to ferment again to prepare a second mixture. Step S12; 상기 제2 혼합물에 지방성분, 페놀성분 또는 탄닌성분을 제거하고, 미활성 고분자 탄수화물과 미생물을 제거하기 위하여 활성탄소 필터가 구비되는 필터링 시스템을 통과시킨 후 얻어지는 제3 혼합물 제조단계(S13); 및A third mixture preparation step (S13) obtained after removing a fat component, a phenol component or a tannin component to the second mixture, and passing through a filtering system having an activated carbon filter to remove inactive polymer carbohydrates and microorganisms; And 상기 제3 혼합물을 감압농축기에 투입한 후, 90~120℃로 가열하여 농축시켜 30브릭스(brix) 이상 도달될 때까지 농축하여 얻어지는 제4 혼합물 제조단계(S14)를 포함하는 것을 특징으로 하는 발모촉진용 조성물 제조방법.Injecting the third mixture into a vacuum concentrator, heated to 90 ~ 120 ℃ concentrated to reach a brix 30 or more (brix) to obtain a hair growth comprising a fourth mixture obtained step (S14) obtained Method for producing a composition for promotion. 제4 항에 있어서,5. The method of claim 4, 상기 제4 혼합물 제조단계를 거쳐 발모촉진 효능을 목적으로 제조되는 샴푸, 린스 또는 토닉에 이용하는 것을 특징으로 하는 발모촉진용 조성물 제조방법.Hair growth promoting composition manufacturing method, characterized in that used in the shampoo, rinse or tonic prepared for the purpose of promoting hair growth through the fourth mixture manufacturing step. 제4 항에 있어서, 5. The method of claim 4, 상기 제4 혼합물 제조단계를 거쳐 발모촉진 효능을 목적으로 제조되는 의약품 또는 의약부외품으로 이용하는 것을 특징으로 하는 발모촉진용 조성물 제조방법.The method for producing a composition for promoting hair growth, characterized in that used as a drug or quasi-drug manufactured for the purpose of promoting hair growth through the fourth mixture manufacturing step. 삭제delete
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KR101434005B1 (en) * 2011-11-03 2014-08-25 주식회사 피비에스 Composition for coating scalp or hair for promoting hair restore by using rice fermentation solution
KR101580216B1 (en) * 2014-05-12 2015-12-24 정승열 Protect and improve the scalp hair with shampoo containing composition and manufacturing method of that.
KR102213447B1 (en) * 2019-03-26 2021-02-05 위샘결 Management method for hairloss and scalp care
KR102109547B1 (en) * 2019-10-31 2020-05-26 (주)루데아 Hair care cosmetic composition included carbonated water and manufacturing method thereof
CN116870074B (en) * 2023-08-14 2024-05-17 江苏春申堂药业有限公司 Chinese medicinal liniment for preventing hair loss and promoting hair growth, and its preparation method

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KR101189605B1 (en) * 2012-06-28 2012-10-11 홍상근 White pleuropterus multiflorus and phlomis umbrosa extract for promoting insulin-like growth factor secretion and bone framework growth, and method for producing the same

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