KR101014074B1 - 기관지확장제 튜로부테롤의 경피투여를 위한 튜로부테롤 염산염을 함유하는 경피 치료 시스템 - Google Patents

기관지확장제 튜로부테롤의 경피투여를 위한 튜로부테롤 염산염을 함유하는 경피 치료 시스템 Download PDF

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Publication number
KR101014074B1
KR101014074B1 KR1020027004866A KR20027004866A KR101014074B1 KR 101014074 B1 KR101014074 B1 KR 101014074B1 KR 1020027004866 A KR1020027004866 A KR 1020027004866A KR 20027004866 A KR20027004866 A KR 20027004866A KR 101014074 B1 KR101014074 B1 KR 101014074B1
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South Korea
Prior art keywords
tulobuterol
transdermal therapeutic
therapeutic system
matrix
layer
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Expired - Fee Related
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KR1020027004866A
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English (en)
Korean (ko)
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KR20020047240A (ko
Inventor
스테판 브락트
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에르테에스 로만 테라피-시스테메 아게
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Publication of KR20020047240A publication Critical patent/KR20020047240A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020027004866A 1999-10-16 2002-04-16 기관지확장제 튜로부테롤의 경피투여를 위한 튜로부테롤 염산염을 함유하는 경피 치료 시스템 Expired - Fee Related KR101014074B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19950066A DE19950066A1 (de) 1999-10-16 1999-10-16 Transdermales therapeutisches System mit einem Gehalt an Tulobuterol-hydrochlorid zur Verabreichung des Bronchodilatators Tulobuterol über die Haut
DE19950066.5 1999-10-16

Publications (2)

Publication Number Publication Date
KR20020047240A KR20020047240A (ko) 2002-06-21
KR101014074B1 true KR101014074B1 (ko) 2011-02-14

Family

ID=7925993

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027004866A Expired - Fee Related KR101014074B1 (ko) 1999-10-16 2002-04-16 기관지확장제 튜로부테롤의 경피투여를 위한 튜로부테롤 염산염을 함유하는 경피 치료 시스템

Country Status (12)

Country Link
US (1) US7056528B1 (https=)
EP (1) EP1220662B1 (https=)
JP (2) JP4874486B2 (https=)
KR (1) KR101014074B1 (https=)
AR (1) AR026040A1 (https=)
AT (1) ATE299019T1 (https=)
AU (1) AU7662400A (https=)
CA (1) CA2387143C (https=)
DE (2) DE19950066A1 (https=)
ES (1) ES2245648T3 (https=)
PT (1) PT1220662E (https=)
WO (1) WO2001028531A1 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100469995B1 (ko) * 2002-05-20 2005-02-05 안국약품 주식회사 천식치료제를 함유한 매트릭스형 패취
WO2004112770A1 (ja) * 2003-06-20 2004-12-29 Teikoku Seiyaku Co., Ltd. ツロブテロール含有貼付剤
DE10340152B4 (de) 2003-09-01 2006-05-04 BÖCO Böddecker & Co. GmbH & Co. KG Schloß mit einer Drehfalle und einer Sperrklinke
CA2542778C (en) * 2003-10-28 2012-05-29 Noven Pharmaceuticals, Inc. Transdermal drug delivery composition
CN1297257C (zh) * 2004-01-02 2007-01-31 上海现代药物制剂工程研究中心有限公司 含有妥洛特罗的压敏胶，透皮贴剂及制备方法和应用
WO2006051818A1 (ja) * 2004-11-10 2006-05-18 Hisamitsu Pharmaceutical Co., Inc. 外用製剤及び貼付剤
EP1806151B1 (en) * 2004-11-10 2012-05-23 Hisamitsu Pharmaceutical Co., Inc. Drug for external use and adhesive patch
US8080560B2 (en) * 2004-12-17 2011-12-20 3M Innovative Properties Company Immune response modifier formulations containing oleic acid and methods
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
CA3172541C (en) * 2009-06-05 2026-04-14 Durr Systems, Inc. Improved infrared float bar
JP5766475B2 (ja) * 2010-03-30 2015-08-19 日東電工株式会社 貼付製剤およびその製造方法
EP2688561B1 (en) * 2011-03-24 2018-08-22 Teikoku Pharma USA, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
JP5941466B2 (ja) * 2011-07-21 2016-06-29 帝國製薬株式会社 水性貼付剤
CN102552221B (zh) * 2012-01-11 2013-09-04 中国人民解放军军事医学科学院微生物流行病研究所 一种妥洛特罗贴剂及其制备方法
NZ628481A (en) * 2012-01-11 2016-11-25 Adelaide Res & Innovation Pty Stabilising and analysing fatty acids in a biological sample stored on solid media
AU2013338243B2 (en) 2012-11-02 2016-09-29 Teikoku Seiyaku Co., Ltd. Propynylaminoindan transdermal compositions
US9962349B2 (en) 2014-10-17 2018-05-08 Fidia Farmaceutici S.P.A. Dermal therapeutic system with high adhesivity
EP3395336A1 (en) 2017-04-28 2018-10-31 Nitto Denko Corporation Transdermal absorption preparation
CN109541065B (zh) * 2018-12-04 2019-10-01 山东大学 一种妥洛特罗贴剂的分析方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990062986A (ko) * 1997-12-12 1999-07-26 가마이 고로 경피 흡수형 제제

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
AU578275B2 (en) * 1984-03-01 1988-10-20 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Pharmaceutical compositions
JPH0725669B2 (ja) 1988-12-23 1995-03-22 日東電工株式会社 経皮投与用医薬製剤
DE4002281A1 (de) * 1990-01-26 1991-08-01 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit dem wirkstoff tulobuterol
IT1251469B (it) 1991-07-15 1995-05-15 Zambon Spa Sistema terapeutico transdermale per la somministrazione di farmaci ad attivita' broncodilatante.
EP0593807A1 (en) * 1992-10-22 1994-04-27 LTS Lohmann Therapie-Systeme GmbH & Co. KG Patch for transdermal administration of volatile pharmaceutically active ingredients of chemically basic nature and a process for preparation
ES2180546T3 (es) * 1992-07-23 2003-02-16 Hisamitsu Pharmaceutical Co Composicion basica administrable percutaneamente y composicion de farmaco preparada a partir de ella.
JP2753800B2 (ja) * 1994-04-14 1998-05-20 日東電工株式会社 経皮吸収型製剤
JP3466305B2 (ja) * 1994-12-12 2003-11-10 久光製薬株式会社 溶解剤および該溶解剤を含有する外用製剤
EP0943330A4 (en) * 1996-10-04 2001-08-16 Saitama Daiichi Seiyaku Kabush BAND AID
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
IT1294748B1 (it) * 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
KR19990062986A (ko) * 1997-12-12 1999-07-26 가마이 고로 경피 흡수형 제제

Also Published As

Publication number Publication date
JP4874486B2 (ja) 2012-02-15
WO2001028531A1 (de) 2001-04-26
AU7662400A (en) 2001-04-30
AR026040A1 (es) 2002-12-26
DE19950066A1 (de) 2001-04-26
EP1220662B1 (de) 2005-07-06
JP2003528037A (ja) 2003-09-24
PT1220662E (pt) 2005-10-31
KR20020047240A (ko) 2002-06-21
EP1220662A1 (de) 2002-07-10
US7056528B1 (en) 2006-06-06
CA2387143C (en) 2009-06-02
DE50010679D1 (de) 2005-08-11
ES2245648T3 (es) 2006-01-16
JP2011252003A (ja) 2011-12-15
ATE299019T1 (de) 2005-07-15
CA2387143A1 (en) 2001-04-26

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