KR100946603B1 - 제라닐기 함유 화합물 - Google Patents
제라닐기 함유 화합물 Download PDFInfo
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- KR100946603B1 KR100946603B1 KR1020097005493A KR20097005493A KR100946603B1 KR 100946603 B1 KR100946603 B1 KR 100946603B1 KR 1020097005493 A KR1020097005493 A KR 1020097005493A KR 20097005493 A KR20097005493 A KR 20097005493A KR 100946603 B1 KR100946603 B1 KR 100946603B1
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- South Korea
- Prior art keywords
- acid
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- geranyl
- amide
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- 0 CC(C)=CCCC(C)=CCNC(*C(C(O*)=O)OC(*)=O)=O Chemical compound CC(C)=CCCC(C)=CCNC(*C(C(O*)=O)OC(*)=O)=O 0.000 description 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/05—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/49—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/74—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/02—Thiols having mercapto groups bound to acyclic carbon atoms
- C07C321/08—Thiols having mercapto groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
- C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/033—Uronic acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Abstract
Description
피험물질 | 항종양 효과 | 독 성 | 종합 평가 | |
체중 감소 | 사망률 | |||
N-라제닐구론산아미드 | ++ | +/- | - | ++ |
N-제라닐갈락투론산아미드 | +++ | +/- | +/- | |
N-갈락토실제라닐산아미드 | +++ | + | - | +++ |
N-푸코오스제라닐산아미드 | ++ | +/- | - | +++ |
피험물질 | 항종양 효과 | 독 성 | 종합 평가 | |
체중 감소 | 사망률 | |||
N,N-디제라닐말산디아미드 | + | + | - | ++ |
N,N-디제라닐푸마르산디아미드 | ++ | +/- | - | ++ |
N-제라닐-4-피루보아미노벤조산아미드 | ++ | - | - | +++ |
N-제라노일티로신 | ++ | +/- | - | ++ |
티로신제라닐아미드 | + | +/- | - | + |
N-아세틸티로신제라닐아미드 | + | +/- | - | + |
피험물질 | 항종양 효과 | 독 성 | 종합 평가 | |
체중 감소 | 사망률 | |||
N-글루코실메발론산아미드 | ++ | +/- | - | +++ |
Claims (3)
- 제 1 항에 기재된 식 (Ⅰ-2) 의 제라닐기 함유 화합물을 유효성분으로서 함유하는 항종양제.
- 활성 유효량의 제 1 항에 기재된 식 (Ⅰ-2)의 제라닐기 함유 화합물 및 제약학적으로 허용할 수 있는 담체 또는 희석제를 함유하여 이루어지는 암 치료용 제약학적 조성물.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002004131 | 2002-01-11 | ||
JP2002004123A JP4010814B2 (ja) | 2002-01-11 | 2002-01-11 | メバロン酸誘導体 |
JP2002004136A JP4109453B2 (ja) | 2002-01-11 | 2002-01-11 | ゲラニル基含有アミド誘導体 |
JPJP-P-2002-004123 | 2002-01-11 | ||
JPJP-P-2002-004131 | 2002-01-11 | ||
JPJP-P-2002-004136 | 2002-01-11 | ||
JPJP-P-2002-283644 | 2002-09-27 | ||
JP2002283644A JP3989808B2 (ja) | 2002-01-11 | 2002-09-27 | ゲラニル−糖誘導体 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020047010776A Division KR100908595B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20090036149A KR20090036149A (ko) | 2009-04-13 |
KR100946603B1 true KR100946603B1 (ko) | 2010-03-09 |
Family
ID=27482764
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020097005493A KR100946603B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
KR1020097005494A KR100946602B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
KR1020097005495A KR100900179B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
KR1020047010776A KR100908595B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020097005494A KR100946602B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
KR1020097005495A KR100900179B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
KR1020047010776A KR100908595B1 (ko) | 2002-01-11 | 2002-12-26 | 제라닐기 함유 화합물 |
Country Status (12)
Country | Link |
---|---|
US (4) | US7125852B2 (ko) |
EP (4) | EP2404894B1 (ko) |
KR (4) | KR100946603B1 (ko) |
CN (1) | CN1307148C (ko) |
AT (1) | ATE519733T1 (ko) |
AU (1) | AU2002361126C1 (ko) |
BR (1) | BRPI0215485B8 (ko) |
CA (4) | CA2706832C (ko) |
MX (1) | MXPA04006636A (ko) |
TW (1) | TWI230162B (ko) |
WO (1) | WO2003059866A1 (ko) |
ZA (1) | ZA200404877B (ko) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
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AU2008272854B2 (en) * | 2007-07-03 | 2014-03-13 | Children's Hospital & Research Center At Oakland | Inhibitors of polysialic acid de-N-acetylase and methods for using the same |
AU2009221765B2 (en) * | 2008-03-05 | 2015-05-07 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
US8198327B2 (en) | 2008-04-09 | 2012-06-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Fatty acid amides and uses thereof |
DE102008042421A1 (de) | 2008-09-26 | 2010-04-01 | Symrise Gmbh & Co. Kg | Geranylaminderivate der Oxalsäure |
GB0902849D0 (en) * | 2009-02-19 | 2009-04-08 | Givaudan Sa | Organic compounds |
WO2013149031A2 (en) | 2012-03-30 | 2013-10-03 | Givaudan S.A. | Powder flavour composition |
WO2013149019A1 (en) | 2012-03-30 | 2013-10-03 | Givaudan S.A. | N-acylated methionine derivatives as food flavouring compounds |
US10201175B2 (en) | 2012-03-30 | 2019-02-12 | Givaudan Sa | N-acylated 1-aminocycloalkyl carboxylic acids as food flavouring compounds |
SG11201405342TA (en) | 2012-03-30 | 2014-10-30 | Givaudan Sa | N-acyl proline derivatives as food flavouring compounds |
BR112014023016B1 (pt) | 2012-03-30 | 2020-10-27 | Givaudan Sa | composição de sabor e composição comestível |
JP6224072B2 (ja) | 2012-03-30 | 2017-11-01 | ジボダン エス エー | フレーバープロフィール食用組成物の改良のためのn−アシル−アミノ酸誘導体 |
KR102045591B1 (ko) | 2012-03-30 | 2019-12-02 | 지보당 에스아 | 식품 향미 화합물로서의 감마 아미노-부티르산 및 베타 알라닌의 n-아실 유도체 |
WO2013157926A1 (en) * | 2012-04-19 | 2013-10-24 | Nyken Holding B.V. | Geranyl geranyl acetone analogs and uses thereof |
WO2015050534A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
GB201317424D0 (en) | 2013-10-02 | 2013-11-13 | Givaudan Sa | Improvements in or relating to organic compounds |
CN105636457B (zh) | 2013-10-02 | 2020-03-10 | 奇华顿股份有限公司 | 具有味道改进特性的有机化合物 |
WO2015050536A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | N-acylated 2-aminoisobutyric acid compounds and flavour compositions containing them |
WO2015050537A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
WO2015050538A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
WO2015050535A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
EP3057444B1 (en) | 2013-10-02 | 2017-12-06 | Givaudan SA | Organic compounds having taste-modifying properties |
CN106999469A (zh) * | 2014-11-12 | 2017-08-01 | 维索利斯有限公司 | 由甲羟戊酸内酯和衍生物制备的聚合物 |
US9889120B2 (en) | 2016-01-14 | 2018-02-13 | Vicus Therapeutics, Llc | Combination drug therapies for cancer and methods of making and using them |
EP4192441A1 (en) * | 2020-08-06 | 2023-06-14 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Oleylcysteineamide or derivatives thereof and their use in therapy |
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2002
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04331983A (ja) * | 1991-05-08 | 1992-11-19 | Hitachi Ltd | 表示装置 |
Non-Patent Citations (1)
Title |
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三橋 博 등, 天然物化學 개정 제4판, p.33, 1983 |
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