KR100898960B1 - A soap composition for atopic dermatitis containing fermented extract of Xanthium strumarium L. and preparation method thereof - Google Patents

Abstract

The present invention relates to a soap and a method for producing a soap, and relates to a soap composition and a method for producing a fermented broccoli having an excellent effect on atopic dermatitis by adding the fermented broccoli in the production of soap.

The soap composition according to the present invention has little skin irritation, has excellent skin moisturizing power, and shows an excellent effect on relief of symptoms when applied to atopic dermatitis patients.

Soap, Dogweed, Charcoal, Skin, Atopy

Description

A soap composition for atopic dermatitis containing fermented extract of Xanthium strumarium L. and preparation method

The present invention relates to a soap and a method for producing a soap, and relates to a soap composition and a method for producing a fermented broccoli having an excellent effect on atopic dermatitis by adding the fermented broccoli in the production of soap.

Atopic skin is a type of skin inflammation characterized by erythema, edema, severe pruritis, exudation and crusting. The acute phase forms blisters in the epidermis, while the chronic phase develops scaling and thickening of the skin. It is well known that genetic factors of atopic dermatitis are involved and have a family history of atopic dermatitis, asthma and allergic rhinitis in more than 50% of the patient family. Clinical observations show that foods such as eggs, milk and flour are important allergens in young children, while indoor dust, pollen, mold and dandruff in hairy animals are the major causes in large children.

To date, atopic dermatitis has been treated with immunotherapy and pharmacotherapy, but there are no special treatments. If the symptoms are severe, steroids (adrenal corticosteroids) have been used, but they are effective only for short-term clinical symptoms. Most of the effects are induced. Long-term topical administration of steroids leads to a decrease in adrenal function, resulting in side effects caused by various corticosteroids, which is inappropriate for continued use. Since there is no appropriate treatment for atopic dermatitis patients, in many cases they rely on constitution improvement, folk remedies and herbal treatment. Therefore, the development of products that can alleviate the symptoms of patients with atopic dermatitis gradually increasing due to environmental changes and industrialization.

Soap with less skin irritation is made by using vegetable materials to mix fats and oils in proper amounts, dissolve by heating, and add sodium hydroxide to induce saponification reaction. By-products in the lower layer are removed and dried in vacuo to prepare a soap. Antioxidants, moisturizers, fragrances, etc. may be added to the prepared soaps.

On the other hand, Korean Patent No. 634816 discloses a herbal cleanser comprising a medicinal herb, sodium hydrogen carbonate, tri-sugar and fermentation agent for fermenting them and a thickener as wine, honey and stabilizing material. In addition, jade, wood vinegar, charcoal, etc. have already been used in the manufacture of other functional soaps, but since the effects on atopic dermatitis are not high, there is an increasing demand for a soap composition having a clear effect of atopic dermatitis.

The present inventors tried to find a better raw material in order to overcome the problems of conventional atopic dermatitis soap, and by adding the fermentation broth prepared by grinding the fermented mixed with sugar without drying dry sprouts or mature docomari, and then pulverized Soap has been found to have excellent skin moisturizing properties and significantly relieve the symptoms of atopic dermatitis.

Accordingly, it is an object of the present invention to provide a soap composition excellent in skin moisturizing power and amelioration effect of atopic dermatitis and a method for producing the same.

The present invention relates to a soap composition containing a docked horse fermented broth and a method for preparing the same, and more particularly, to a soap composition and a method for preparing the same, which are contained in a soap base of a vegetable oil or fat component. to provide.

The soap composition according to the present invention has a more excellent moisturizing effect when using rapeseed oil as a vegetable oil-based component of the soap base, and has a better effect on atopic dermatitis when pine charcoal powder having excellent antibacterial activity is added to the fermented broccoli. .

In addition, the fermented broccoli fermentation broth, the leaves, stems, roots or a mixture thereof is added to ferment at room temperature and then fermented at room temperature, it is preferable to use that prepared by grinding in a mixer or grinder as it is, before adding sugar to the leaves, stems It further comprises the step of aging the root or a mixture thereof for 10 to 30 hours at 60 to 70 ℃ shows a better effect on the relief of the symptoms of atopic dermatitis.

Hereinafter, the present invention will be described in more detail.

At this time, if there is no other definition in the technical terms and scientific terms used, it has a meaning commonly understood by those of ordinary skill in the art.

In addition, repeated description of the same technical configuration and operation as in the prior art will be omitted.

The present invention provides a soap composition prepared by mixing the fermented broccoli liquid with a soap base of vegetable oil and fat and a method for producing the same. Soap composition according to the present invention has excellent skin moisturizing power, and when applied to atopic skin patients, atopic dermatitis is remarkably alleviated.

Conventional soaps (cosmetic soaps, cosmetic soaps, etc.) are alkali metal soaps and fatty acids obtained from vegetable oils such as palm oil, sugar oil, soybean oil, castor oil, olive oil, and anti-coated oils, and fatty acids and sodium or potassium obtained from animal fats such as tallow, lard, solstice and fish oil. Is used alone or by mixing neutralized mixed alkali metal salts together to produce a soap, and the same vegetable oils and alkaline metal salts are commonly referred to as soap base (soap base).

The soap base according to the present invention produces a soap base by mixing and neutralizing vegetable oils and alkali metal salts in order to further eliminate irritation to the skin and to prevent skin dryness and itching. The vegetable oil for preparing the soap base is preferably olive oil, castor oil, grape seed oil, rapeseed oil and the like, and the use of rapeseed oil is more preferable because it has a high effect on skin moisturization and suppression of itching.

Dokmari (xanthium strumarium) is an annual herb of compositae, is about 1m high and has hairs with leaves. The leaves are regenerated, the plague is long, and 5 ~ 10cm long. Flowers bloom in August-September, flowers are yellow with cones at the ends of branches and stems. There are female flowers and male flowers. The head flower of the male flower is round and hangs at the end. There is a projection. The muzzle is a hook-like projection, elliptical, about 1cm long. There are two achenes (瘦果). The fruit matures in September, and the achene has a hook like an outer surface that adheres well to the object. In addition, young shoots are eaten and fruit (spear) is used for pain relief, jongjong (丁 腫), jinchang (金 瘡), Chungpok (蟲 毒), water species, water drainage, hemorrhoids, tonsillitis, paralysis It was used to treat rabies, eczema, sweating, syphilis, arthritis, detoxification, diuresis, postpartum pain, toothache, nominal, nag, and headache. Mainly, antiseptic plasters and antiseptic plasters were used to treat eczema, Taesun, sedimentary disease, boils, poduraji, smallpox, and marine dermatitis.

The fermented broccoli according to the present invention is a fermentation broth obtained by fermenting sprouts, leaves, stems, roots, or mixtures thereof, and fermented at room temperature after mixing sugar with the sprouts, leaves, stems, roots, or mixtures thereof. It is preferable to prepare a fermentation broth containing finely pulverized dokomari components by grinding with a mixer or a grinder. The amount of the sugar is preferably 50 to 150 parts by weight of sugar based on 100 parts by weight of the sprouts, leaves, stems, roots or mixtures thereof, which may not be well fermented when the amount of sugar is less than 50 parts by weight, If the amount exceeds 150 parts by weight, the effect of the fermentation broth is no longer increased, so it may be economically disadvantageous, and since the sugar component is not dissolved, it may be difficult to prepare a liquid uniform fermentation broth. It is more preferable that the grinding is carried out after the fermentation is more uniform and finely pulverized than the grinding component before the fermentation. The sugar may be any unrefined sugar, or refined sugars such as white sugar, yellow white sugar and brown sugar (samon sugar). In addition, the buds may use both buds or mature dogs, but the moisturizing effect and the atopic inflammation relieving effect are more excellent when the buds are used.

In addition, when preparing the fermented broccoli fermentation broth contained in the soap composition according to the present invention, if the sprout, leaves, stems, roots or mixtures thereof are pre-treated at 60 to 70 ℃ for 10 to 30 hours before mixing with the subsequent The fermentation is better in the step and accordingly the activity of the fermented broccoli is further improved, resulting in an excellent effect of reducing the atopic inflammation of the soap composition. In the pretreatment step, the bleeding piglet must be processed in the temperature range and in the time range, and thus, the fermentation broth is ripened while containing the appropriate moisture, thereby further increasing the efficacy of the fermentation broth prepared in the sugar fermentation process.

It is preferable that the content of the dog bream fermentation broth contained in the soap composition according to the present invention is 1 to 10 parts by weight, and more preferably 3 to 5 parts by weight based on 100 parts by weight of the vegetable oil. If the content of the fermented broccoli is less than 1 part by weight, the effect of improving atopic dermatitis is insignificant. If the content is more than 10 parts by weight, the increase in the effect of atopic dermatitis is insignificant. This is because it is not easy to manufacture.

The soap composition according to the present invention may further contain pine charcoal powder, and the pine charcoal powder may have a remarkable effect on atopic dermatitis relief and antimicrobial activity as compared to that used alone by synergistic action with a fermentation broccoli.

In general, it is known that charcoal has the ability to adsorb harmful substances. In the present invention, the use of charcoal powder is to remove harmful chemicals present in the skin, and in particular, the use of pine charcoal powder is very easy to prepare into fine particles as compared to the oak charcoal powder, and it is added with a fermented broccoli. This is because it is more effective in relieving symptoms of atopic dermatitis.

The content of pine charcoal added to the soap composition according to the present invention is preferably 0.05 to 5 parts by weight, more preferably 0.1 to 1 part by weight based on 100 parts by weight of vegetable oil. If the content is less than 0.05 parts by weight, the effect of the combined use with the Dokomari fermentation broth does not appear well, and if the content is more than 5 parts by weight, the increase of the effect may be insignificant and may be economically disadvantageous. Aesthetically not good because.

The present invention is a method for producing a soap composition containing a fermented broccoli fermentation broth may be prepared by first preparing a soap base of the vegetable fat and oil and then mixing it with a fermented broccoli fermentation broth, or adding a dokomari fermentation broth to an aqueous sodium hydroxide solution when preparing the soap base It may then be prepared by mixing with vegetable oils and fats. A more preferable method is a method in which a vegetable oil and pine charcoal powder are added and mixed with a mixed solution obtained by mixing a fermented broccoli with an aqueous sodium hydroxide solution and then poured into a mold to cure. In the case of preparing the soap base first and then mixing the dokomari fermentation broth, there may be a problem that the dokomari fermentation broth is not easily mixed evenly with the soap or hardened properly.

As described above, the soap composition according to the present invention uses a soap base of vegetable fat and oil, and contains dokmari fermentation broth and additional pine charcoal powder, which has little skin irritation, excellent skin moisturizing power, and relieves symptoms when applied to atopic dermatitis patients. Excellent effect.

The present invention will be described in more detail with reference to the following Examples. However, the following examples are only examples of the present invention, and the claims of the present invention are not limited thereto.

Production Example 1 Preparation of Tokomari Fermentation Broth

After harvesting the grown-up skewered dog, wash it with running water about five times, remove the water by applying it to the stem, and cut leaves, stems, and roots to the size of 1 cm or less, and add 100 parts by weight of brown sugar to 100 parts by weight of The mixture was fermented at room temperature for 20 days. This was put in a blender and ground to prepare a liquid dokomari fermentation broth with uniform and finely ground docomari leaves, stems and roots.

Production Example 2 Preparation of Tokomari Fermentation Broth

To prepare a fermented broccoli fermentation broth in the same manner as in Preparation Example 1, the process of further aged for 10 hours in a thermostat maintained at 65 degrees before the shredded dork is mixed with sugar.

Preparation Example 3 Preparation of Dokomari Fermentation Broth

A fermentation broth was prepared in the same manner as in Preparation Example 1, except that the shoots having the number of leaves of about 5 instead of the mature docomari were used.

[Comparative Production Example] Production of powder Xanthium strumarium

After harvesting the grown-up macaw, the roots were washed about 5 times in running water, and then drained by the water, and dried at room temperature until the mass became 10% of the mass before drying. The dried macaw was chopped and pulverized to prepare a macaw powder.

[Examples 1 to 4] Preparation of Atopic Skin Soap

Table 1 shows the content of ingredients added to soap production with 100 parts by weight of rapeseed oil. In the method of preparing a soap, when using a dokomari fermentation broth, purified water and sodium hydroxide were mixed first to prepare a sodium hydroxide solution, and then a dokomari fermentation broth was added to the sodium hydroxide solution and mixed to prepare a mixed solution. The remaining ingredients were added to the mixed solution, mixed well, poured into a mold, and then cured by keeping at 30 ° C for 24 hours.

[Comparative Examples 1 and 2]

Soap was prepared in the same manner as in Example 1 by adding only docomari powder or pine charcoal powder without using the dokomari fermentation broth. In the comparative example without using the dokomari fermentation broth shown in Table 1, the oil and the remaining components of the soybean hydroxide solution The mixture was added and mixed well, and then cured in the same manner as in Example.

TABLE 1

[Test Example]

For the soaps prepared in Examples 1 to 4 and Comparative Examples 1 and 2 (1) cleaning power (2) moisturizing power after use (3) to examine the alleviation effect of atopic symptoms 10 patients 60 with atopic dermatitis Each group is divided into six groups, and the soap of Example 1 is in group 1, the soap of Example 2 is in group 2, the soap of example 3 is in group 3, the soap of example 4 is in group 4, the soap of comparative example 1 is in group 5, Group 6 was given a soap of Comparative Example 2 to be used more than once a day and to evaluate the effect after 10 days. At this time, the evaluation was performed according to the criteria of very good (5 points), excellent (4 points), moderate (3 points), bad (2 points), very bad (1 point), and the results were averaged to the following table. 2 is shown.

TABLE 2

As can be seen from the results of the above table, it can be seen that the soap of the example has an excellent effect on relieving power, moisturizing power, and atopic symptoms compared to the soap of the comparative example. It can be seen that the soaps of Examples 2 to 4, which contain docomari fermentation broth and pine charcoal powder, have very good effects, and thus, when the dokomari fermentation broth and pine charcoal powder are used in combination, the effect of moisturizing and atopic symptoms is more effective. It can be seen that. In particular, Examples 2 and 4 were the best in terms of washing power, moisturizing power and atopic symptoms.

Claims (7)

50 to 150 parts by weight of sugar is mixed with 100 parts by weight of sprouts, leaves, stems, roots, or mixtures of the dried dogs, which are dried, and then mixed with fermentation broth prepared by grinding, sodium hydroxide solution and pine charcoal powder. Soap prepared by the method of molding and curing after adding the rapeseed oil to the mixed solution. delete The method of claim 1, The dokomari fermentation broth is soap, characterized in that further comprising the step of maturing doukmari sprouts, leaves, stems, roots or mixtures thereof at 60 to 70 ℃ for 10 to 30 hours. delete delete The method according to claim 1 or 3, The dokomari fermentation broth is 1 to 10 parts by weight based on 100 parts by weight of rapeseed oil, the pine charcoal is characterized in that using 0.05 to 5 parts by weight based on 100 parts by weight of rapeseed oil. delete