KR100835874B1 - 요실금 치료용의 치환된 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물의 용도 - Google Patents

요실금 치료용의 치환된 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물의 용도 Download PDF

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Publication number
KR100835874B1
KR100835874B1 KR1020037007316A KR20037007316A KR100835874B1 KR 100835874 B1 KR100835874 B1 KR 100835874B1 KR 1020037007316 A KR1020037007316 A KR 1020037007316A KR 20037007316 A KR20037007316 A KR 20037007316A KR 100835874 B1 KR100835874 B1 KR 100835874B1
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KR
South Korea
Prior art keywords
dimethylaminomethyl
formula
incontinence
urinary
alkyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020037007316A
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English (en)
Korean (ko)
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KR20030055335A (ko
Inventor
크리스토프토마스
프리데리히스엘마
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그뤼넨탈 게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020037007316A 2000-11-30 2001-11-28 요실금 치료용의 치환된 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물의 용도 Expired - Fee Related KR100835874B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10059413.1 2000-11-30
DE10059413A DE10059413A1 (de) 2000-11-30 2000-11-30 Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
PCT/EP2001/013917 WO2002043714A2 (de) 2000-11-30 2001-11-28 Verwendung von substituierten 6-dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur therapie der harninkontinenz

Publications (2)

Publication Number Publication Date
KR20030055335A KR20030055335A (ko) 2003-07-02
KR100835874B1 true KR100835874B1 (ko) 2008-06-09

Family

ID=7665211

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020037007316A Expired - Fee Related KR100835874B1 (ko) 2000-11-30 2001-11-28 요실금 치료용의 치환된 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물의 용도

Country Status (25)

Country Link
US (2) US20040029878A1 (https=)
EP (1) EP1353660B1 (https=)
JP (1) JP4284065B2 (https=)
KR (1) KR100835874B1 (https=)
CN (1) CN1518444B (https=)
AT (1) ATE315387T1 (https=)
AU (2) AU2002223688B2 (https=)
BR (1) BR0115881A (https=)
CA (1) CA2430282C (https=)
CY (1) CY1105142T1 (https=)
CZ (1) CZ299343B6 (https=)
DE (2) DE10059413A1 (https=)
DK (1) DK1353660T3 (https=)
EC (1) ECSP034632A (https=)
ES (1) ES2256338T3 (https=)
HU (1) HU227927B1 (https=)
IL (2) IL156140A0 (https=)
MX (1) MXPA03004801A (https=)
NO (1) NO333963B1 (https=)
NZ (1) NZ538924A (https=)
PL (1) PL203093B1 (https=)
RU (1) RU2279875C2 (https=)
SK (1) SK287536B6 (https=)
WO (1) WO2002043714A2 (https=)
ZA (1) ZA200304999B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
US20110060053A1 (en) * 2002-09-09 2011-03-10 Gruenenthal Gmbh Crystalline Modifications of 6-Dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol
DE10333835A1 (de) * 2003-07-24 2005-03-10 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
AR062420A1 (es) * 2006-08-28 2008-11-05 Schering Corp Proceso e intermediarios para la sintesis de derivados e intermediarios de (3- alquil-5- piperidin -1-il-3,3a- dihidro- pirazolo [1,5-a] pirimidin -7-il) amino
DE102007022790A1 (de) 2007-05-11 2008-11-20 Grünenthal GmbH Axomadol zur Schmerzbehandlung bei Arthrose

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733936A (en) * 1995-07-11 1998-03-31 Gruenenthal Gmbh 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
EP1005861A1 (en) * 1997-04-11 2000-06-07 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371720A (en) * 1980-09-19 1983-02-01 Pfizer Inc. 2-Hydroxy-4-(substituted) phenyl cycloalkanes and derivatives
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
CN1054850C (zh) * 1993-07-30 2000-07-26 德尔塔药物公司 用于治疗的哌嗪化合物
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
PE20010623A1 (es) * 1999-10-05 2001-07-07 Gruenenthal Chemie Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
DE10004926A1 (de) * 2000-02-04 2001-08-09 Gruenenthal Gmbh Verfahren zur enzymatischen Racematspaltung von Aminomethyl-Aryl-Cyclohexanol-Derivaten
US6326404B1 (en) * 2000-02-21 2001-12-04 Gruenenthal Gmbh Use of O-desmethyl-N-mono-desmethyl-tramadol
DE10059411A1 (de) * 2000-11-30 2002-06-13 Gruenenthal Gmbh Verwendung von 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733936A (en) * 1995-07-11 1998-03-31 Gruenenthal Gmbh 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
EP1005861A1 (en) * 1997-04-11 2000-06-07 Nippon Shinyaku Co., Ltd. Remedies for frequent urination and urinary incontinence

Also Published As

Publication number Publication date
CN1518444B (zh) 2011-12-28
HK1061355A1 (en) 2004-09-17
HUP0303268A3 (en) 2007-03-28
CA2430282C (en) 2011-04-12
US20040029878A1 (en) 2004-02-12
US7361690B2 (en) 2008-04-22
HU227927B1 (hu) 2012-06-28
SK287536B6 (sk) 2011-01-04
WO2002043714A3 (de) 2003-08-14
NO20032411D0 (no) 2003-05-27
RU2279875C2 (ru) 2006-07-20
IL156140A0 (en) 2003-12-23
PL365517A1 (en) 2005-01-10
NO333963B1 (no) 2013-10-28
AU2002223688B2 (en) 2006-06-01
PL203093B1 (pl) 2009-08-31
DK1353660T3 (da) 2006-03-06
EP1353660A2 (de) 2003-10-22
CN1518444A (zh) 2004-08-04
RU2003117705A (ru) 2005-01-27
JP4284065B2 (ja) 2009-06-24
WO2002043714A2 (de) 2002-06-06
CZ299343B6 (cs) 2008-06-25
NO20032411L (no) 2003-07-17
ATE315387T1 (de) 2006-02-15
BR0115881A (pt) 2004-01-20
IL156140A (en) 2009-02-11
DE10059413A1 (de) 2002-06-20
ECSP034632A (es) 2003-07-25
CY1105142T1 (el) 2009-11-04
HUP0303268A2 (hu) 2004-01-28
ZA200304999B (en) 2004-08-12
US20050065120A1 (en) 2005-03-24
DE50108711D1 (de) 2006-04-06
CZ20031390A3 (cs) 2003-08-13
ES2256338T3 (es) 2006-07-16
SK5952003A3 (en) 2003-09-11
MXPA03004801A (es) 2003-09-10
KR20030055335A (ko) 2003-07-02
NZ538924A (en) 2006-09-29
JP2004524280A (ja) 2004-08-12
EP1353660B1 (de) 2006-01-11
CA2430282A1 (en) 2002-06-06
AU2368802A (en) 2002-06-11

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KR100835874B1 (ko) 요실금 치료용의 치환된 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물의 용도
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